http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Woo, Je Moon,Shin, Da-Yong,Lee, Sung Ju,Joe, Yeonsoo,Zheng, Min,Yim, Jin Ho,Callaway, Zak,Chung, Hun Taeg Molecular Vision 2012 Molecular vision Vol.18 No.-
<P><B>Purpose</B></P><P>To determine whether curcumin induces expression of the defensive enzyme heme oxygenase-1 (HO-1) and protects cells against oxidative stress in cultured human retinal pigment epithelial cells.</P><P><B>Methods</B></P><P>Effective concentrations and toxicities of curcumin were determined after 3 h of curcumin treatment with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Confluent human retinal pigment epithelium cell lines (ARPE-19) were preincubated with curcumin and oxidatively challenged with H<SUB>2</SUB>O<SUB>2</SUB>. HO-1 expression was determined with western blot analysis. To confirm the protective role of HO-1 in oxidative stress, small interfering RNA (siRNA) against HO-1 or inhibitor of HO-1 was treated with curcumin in retinal pigment epithelium cells. Intracellular levels of reactive oxygen species (ROS) were measured with flow cytometry and confocal microscopy. Apoptosis was evaluated with Annexin V-fluoroscein isothiocyanate staining.</P><P><B>Results</B></P><P>Curcumin had little cytotoxicity at concentrations less than 30 μM, and HO-1 expression was the highest at the 15 μM concentration. At this concentration, curcumin also increased the cytoprotective effect against the oxidative stress of H<SUB>2</SUB>O<SUB>2</SUB> through the reduction of ROS levels in human retinal pigment epithelial cells. Curcumin’s effect on the reduction of ROS was mediated by the increase in HO-1 expression.</P><P><B>Conclusions</B></P><P>Curcumin upregulated the oxidative stress defense enzyme HO-1 and may protect human retinal pigment epithelial cells against oxidative stress by reducing ROS levels.</P>
Ho-166 부착풍선도자를 이용한 방사선 조사의 돼지 관상동맥 스텐트 재협착 예방 효과
김원 ( Kim Won ),정명호 ( Jeong Myeong Ho ),박옥영 ( Park Og Yeong ),정우곤 ( Jeong U Gon ),박우석 ( Park U Seog ),김주한 ( Kim Ju Han ),안영근 ( An Yeong Geun ),조정관 ( Jo Jeong Gwan ),박종춘 ( Park Jong Chun ),강정채 ( Kang Je 한국지질동맥경화학회 ( 구 한국지질학회 ) 2002 韓國脂質學會誌 Vol.12 No.1
배경 : 국내에서 개발된 방사선 동위원소 Holmium-166 (166Ho)은 주로 베타선을 방출하며, 166Ho을 부착한 풍선도자를 이용하여 돼지 관상동맥 재협착 모형에서 풍선확장술 후 신생내막 증식을 전신적 부작용 없이 안전하고 효과적으로 억제하였음을 보고한 바 있다. 본 연구에서는 돼지 관상동맥 스텐트 재협착 모형에서 스텐트 시술 후 신생내막 증식에 의한 재협착 병변을 166Ho 부착 풍선도자를 이용하여 치료하여 그 효과를 관찰하고자 하였다. 방법
Park, Chan-Je,Jeon, Kyung-A,Kwon, Ho-Beom 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.3
본 연구의 목적은 근관내 약제로 사용되는 수산화칼슘의 제거방법이 근관충전 후 치근단 미세누출에 미치는 영향을 알아보기 위함이다. 70개의 발거된 단근치를 엔진구동형 ProFile로 근관형성한 후 수용성 수산화칼슘 제제를 1주일간 적용하고 두 군으로 나누어 각기 다른 방법으로 제거하였다. A군은 NaOCI로 근관세정만을 시행하였으며, B군은 근관형성 시 사용된 file보다 한 단계 큰 크기의 ProFile을 사용하여 근관을 재형성한 후 NaOCI로 세척하였다. 근관충전 후 전기화학적 방법으로 24일 동안 치근단 누출을 측정, 비교하였다. 본 연구의 결과 수산화 칼슘 제거를 위한 두가지 방법은 근관충전후 치근단 미세누출에 있어서 차이가 없음을 알 수 있었다. This study evaluated the effect of two different calcium hydroxide (Ca(OH)_(2)) paste removal techniques on the apical leakage of canals obturated with gutta percha cones and sealer after removing a Ca(OH)_(2) dressing using an electrochemical method. Seventy extracted single-rooted teeth were instrumented on with Profile rotary files under NaOCI irrigation. Fifty-eight canals were filled with calcium hydroxide paste, which was then removed using one of the following two techniques. In group A, calcium hydroxide was removed using only NaOCI irrigation, and in group B, the canals were re-prepared with a Profile rotary files-one size larger than the previous instrument and were irrigated with NaOCI. In both groups, the root surfaces were coated twice with nail varnish from CEJ to an area 4㎜ away from the apex after canal obturation. Apical leakage was measured using an electrochemical method for 24 days. All the specimens showed leakddffqage that increased markedly in the first three days. There was no significant difference between the two groups (p > 0.05). The effect of two calcium hydroxide paste removal techniques on the apical leakage was not different during a short period.
조제호,신인선 한국수학교육학회 1998 初等 數學敎育 Vol.2 No.2
We examined two kinds of problem posing, 'problem making' and 'problem modifying' to find which one is more effective for improving mathematical problem solving ability according to the student's learning-levels and sexes. The results showed that 'problem making' is more effective for high and middle-level groups than 'problem modifying'. There was no big difference according to the sexes. These facts implies that making a problem when a situation was presented is more effective to develop problem solving ability than modifying a problem: modifying some conditions and contents of given problem.
Chinese hamster 난소세포에서 수용성 니켈에 의해 특징적으로 발현되는 유전인자들의 빠른 분석에 관한 연구
성근제,이상한,우기민,송호연,조만희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2
니켈에 의한 암 발생기전 및 세포 독성기전을 이해하고 니켈에 의해 발현에 변화를 보이는 유전자들을 검출하기 위하여 니켈이 포함된 배지에서 배양된 Chinese hamster난소 세포부터 mRNA differential display 분석을 시행하였다. 본 연구에서는 동위원소나 DNA염기서열 분석용 젤을 사용하는 기존의 방법 대신에 훨씬 빠르고, 다루기 쉽고 안전성을 지닌 변형된 기법을 개발하여 적용하였다. 니켈에 의해 발현에 변화를 보이는 cDNA fragments들을 10% polyacrylamide mini젤상에서 분리 및 클로닝한 다음, DNA염기 서열 분석과 GenBank Blast search 프로그램을 이용하여 상동성 조사를 하였다. Reverse Northern blot을 이용하여 발현에 변화가 있는 cDNA들을 재확인한 결과, 검사된 19 cDNAs 들중 총 9종에서 발현의 변화를 보였으며, 이 중 3종은 니켈에 반응하여 발현에 증가를 보였고, 반면에 6종은 발현이 감소하였다.
장주호,김수한,정신,김재휴,강삼석,이제혁 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.4
The authors report clinical results of twenty-three traumatic thoracolumbar burst fractures treated by internal fixation with Kaneda device after anterior decompression during recent three years. Thoracolumbar injuries made up 28.9% of total spinal injuries and the burst fractures treated by anterior decompression and stabilization with Kaneda device constituted 19.0% of all spinal injuries. The burst fractures occurred most frequently at the age of twenties and thirties. The main causes of injury were fall and vehicle accident. Superior end-plate fracture type was most common according to the types of burst fracture. The first and the second lumbar vertebrae were frequently involved. No patient showed neurological deterioration after surgery. Conus medullaris lesions in burst fractures of the thoracolumbar junction have a high potentiality for functional recovery because the lesions are not due to discontinuity or severe crush injury but due to simple compression by bony fragments. The Kaneda device offered enough stability to enable early ambulation with good alignment and solid fusion.
간질발작을 주 증상으로 하는 회백질 이소증을 동반한 Schizencephaly 1례
신석호,양일권,김제헌 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.4
We experienced a case of schizencephaly with heterotopic gray matter that was only manifested a seizure attack. The clinical manifestation of this patient was only seizure without mental retardation, which was controlled by anticonvulsants. The term schizencephaly was introduced by Yakovlev and Wadsworth in 1946 to describe bilatral, nearly symmetrical and full-thickness clefts, which were characterized by an infolding of cortical gray matter along the clefts. The most widely accepted theory for the pathogenesis of this anomaly is the failure of formation of a segment of the germinal matrix or segmental failure of neuronal migration. Heterotopic gray matter is frequently found within and near the cleft. Patients who have these condition present clinically with seizures and developmental delay, and abnormal motor skills are noted in the more severly affected cases. Recognition is important for planning proper treatment and for genetic counseling.
(128, 122) Extended Reed-Solomon Codec 구현
김제환,이찬호 崇實大學校 1999 論文集 Vol.29 No.1
A (128, 122) extended Reed-Solomon cosec is designed based on 'Digital Video Transmission for Cable Television' of SCTE. The decoder is designed using a transform decoding method, and Berlekamp-Massey algorithm is used to compute the error-locator polynomial. The decoder is composed of syndrome calculation unit, a frequency domain error vector calculation unit, and a inverse Fourier transform unit. The codec is implemented in a CPLD chip and the encoded and decoded words are measured and verified to be correct.