노인 되기와 성찰의 시간들 : 박완서, 최일남, 김원일 소설을 중심으로

오혜진 남서울대학교 2010 남서울대학교 논문집 Vol.16 No.2

Now, our society become 'an aged society' and then the problem of old men's life are quiet serious. At the literature, there are a few works that represents dementia nd family conflicts but there are few works the old men say their viewpoint. Around 2000th. Park-wan-seou, Choi-il-nam and Kim-won-il, they are so-called 'old men', write old men's novels. Three novelists say the age of old at the other point. Park-wan-seou try to tell just a human, better than the old men, and solve the problem family conflict. She grow old herself, recognizes her ages. Choi-il-nam express at the problems of old men's daily life and the death, always lightly. It is very interesting and fresh old men's novel style. Kim-won-il's novels are different two the works. He shows the last time four old men life. Four persons had stormy career each other. Sometimes they tried to live only theirselves, sometimes help other people, make a mistakes. Kim-won-il asks the readers what is a true life or false life. Three writers acquire a special meaning that we should be an old man and die. Key words : Park-wan-seou, Choi-il-nam, Kim-won-il, old men's novel, the death, what is a true life or false life.

δ-catenin overexpression promotes angiogenic potential of CWR22Rv-1 prostate cancer cells via HIF-1α and VEGF

He, Y.,Kim, H.,Ryu, T.,Kang, Y.,Kim, J.A.,Kim, B.H.,Lee, J.H.,Kang, K.,Lu, Q.,Kim, K. North-Holland Pub ; Elsevier Science Ltd 2013 FEBS letters Vol.587 No.2

This study revealed that CWR22Rv-1 cells overexpressing δ-catenin display bigger tumor formation and higher angiogenic potentials than their matched control cells in the CAM assay. In addition, δ-catenin overexpression in CWR22Rv-1 cells results in increased hypoxia-inducible factor 1-alpha (HIF-1α and vascular endothelial growth factor (VEGF) expression. Furthermore, δ-catenin overexpression was found to enhance nuclear distribution of both β-catenin and HIF-1α in hypoxic condition, which is diminished by knockdown of δ-catenin. Our current study adds novel evidence regarding contribution of δ-catenin to the progression of prostate cancer.

이주를 경험한 남녀의 서사를 통해 본 친밀한 관계성의 변화

이혜진 이화여자대학교 한국여성연구소 : 이화여자대학교 한국여성연구원 2013 여성학논집 Vol.30 No.2

This study investigates how migration experiences have affected to gender consciousness and intimate relationship between South Koreans in Japan Migrant workers have experienced the change of intimate relationship with their cross-border move(migration). In particular, they have given the meaning of the place as not the foreign one but making relationship as their daily lives through a long-term life in the foreign country. The status of ‘illegal stay’ acts as an element which makes difficult coming and going to their hometowns and family so that they have experienced the change of intimacy in the spiral of the relationship unconsciously or consciously. It is the intimate relation area where is overlapped of sexuality, gender consciousness and a family norm that remarkably appear realistic society, ritual and conflict between their body and mind. Therefore, focusing on the relations between migration experience and intimacy, this research reveals that the relations between ‘illegal stay’ status and intimate relationship are formulated within the limited social network, lead to work opportunity and income stability in itself and function as mechanism of maintaining their life as migrants. 본 연구는 이주 경험자의 젠더의식 및 친밀한 관계성에 이주 경험이 어떤 변화를 발생시켰는지를 고찰하고자 한다. 국경을 넘는 이동을 계기로 이주자들은 친밀한 관계성의 변용을 경험하게 되는데, 특히 장기간에 걸친 타향(他鄕)에서의 생활은 그곳이 이미 타향이 아니라, 자신의 일상의 현실로서 새로운 관계성을 형성하게 된다. 이주자들은 의식적이든, 무의식적이든 그 관계성에 휘말려, 어쩔 수 없이 자신의 친밀권(親密圈)의 변용을 경험하게 된다. 또한, 섹슈얼리티와 젠더의식, 가족규범이 중첩하는 친밀한 관계성의 영역을 분석하여 자신이 실제로 존재하고 있는 현실 사회와 그들의 삶을 관장하는 의식 및 몸의 경합이 이주자들의 삶에서 어떻게 드러나고 있는지 살펴본다. 따라서 본 연구는 이주경험과 친밀한 관계성의 관계에 주목하여, 이주자가 가진‘불법’적 지위와 친밀한 관계성의 성격은, 그들이 가질 수 있는 극히 제한된 사회적 연결망 속에서 형성되고, 친밀한 관계성 자체가 일자리 및 소득의 확보와 연결되며, 이주자로서의 전면적인 삶을 유지할 수 있는 기제로 작용하고 있음을 밝혔다.

신체장애인의 우울발달궤적 예측요인 : 한국복지패널을 이용하여

조혜정,서인균 한국장애인고용촉진공단 고용개발원 2012 장애와 고용 Vol.22 No.1

본 연구의 목적은 성인 신체장애인의 우울발달궤적과 그 예측요인을 파악하는 것이다. 연구를 위해 한국복지패널(Korea Welfare Panel Study)에서 제공한 1차년도에서 4차년도 자료를 활용하였으며, 가구원이 만 19세에서 65세 미만에 해당되는 사람 중 신체장애인 총 610명을 대상으로 분석하였다. 잠재성장모형으로 분석한 결과 첫째, 신체장애인의 우울발달궤적은 선형모형으로 변화하였고, 매년 감소하는 추세로 나타났다. 둘째, 우울발달궤적의 예측요인을 분석한 결과, 우울의 초기값에는 성별, 연령, 근로유무, 빈곤, 장애수준, 문제음주, 자아존중감, 가족관계 만족도가 영향을 미쳤고, 변화율에는 문제음주, 자아존중감만이 영향을 미치는 것으로 나타났다. 이러한 연구결과들을 바탕으로 신체장애인의 정신건강 향상을 위한 실천적, 정책적 함의에 대해 논의하였다. The purpose of this study was to examine the predictors of depression trajectory among physical disabilities. This study examines the predictors of depression trajectory using latent growth curve modeling involving individuals aged between 19 years old and 64 years old who participated in the Korea Welfare Panel Study(N=610). The findings of the study were as follows:: First, the depression trajectory of physical disabilities was decreased depression symptoms each year as linear model. Second, the demographic variables and partial of psychosocial variables(ie. problem drinking, self-esteem, family relationship) were significantly associated with the levels of depressive symptoms at wave 1. And the variables on the rate of depressive symptoms change were problem drinking and self-esteem. Based upon these findings we suggest to develop an integrated psychosocial intervention for mental health promotion about physical disabilities. The implications and limitations of these findings were discussed, and directions for future studies were also proposed.

입지 유형에 따른 맥락적 형태 표현에 관한 연구 : 1980년대 이후 일본 지역 테마 전시관 입면을 중심으로 Focused on the Elevations of Theme Museums Established on Provincial Area in Japan since 1980's

박혜경,김정재 대한건축학회 2003 대한건축학회논문집 Vol.19 No.12

This study is to analyze the trends of the formal expression of contextual attitudes about the local theme museums in Japan. Architectural design by the contextual codes has been considered as an appropriate way to build up the regional identity in these days. After a theoretical study on 'Context', a statistical analysis was processed about the correlations between the types of the locations and the types of forms related with the elevation. At the last stage of the study, the specific methods for expression were studied. The contextual attitudes of continuity characterized into two concepts like continuity and resemblance. As the result of the research, the contextual forms appeared strong with such location types as beaches or plains comparing to mountains or downtown. On the other hand, the conditions of mountains or downtown tend to make the form complicated and divided for adjustment to the context of surroundings. The various expression methods like unifying with the land, applying the configuration of the ground to the shape of the building, using the clear or reflective materials and dividing the mass were researched as helping continuity and resemblance between building and landscape.

Methoprene 처리에 따른 매미나방(Lymantria dispar L.) 유충의 중장상피와 혈림프단백질 함량

박혜숙,이경로 建國大學校基礎科學硏究所 1991 理學論集 Vol.16 No.-

매미나방(Lymantria dispar L.) 유충에 JH mimics인 methoprene을 처리하여 형태학적·생리학적 영향을 조사한 결과는 다음과 같다. 중장상피의 형태학적인 변화는 대조군과 처리군 유충의 원주세포(columnar cell)와 배상세포(goblet cell)에서 관찰하였다. 처리군의 원주세포는 지질성 과립수가 현저하게 증가하였고 핵은 커지고 조면소포체(rough endoplasmic reticulum)는 원형으로 팽대되였다. 세포표면의 미세융모(microvilli)는 거의 영향을 받지 않았다. 미토콘드리아가 내재된 배상세포의 세포질 돌출부는 거의 해체되고 세포질성의 많은 조각(또는 swirled membrane bodies)들이 배상세포의 내강(goblet cavity)으로 배출되었다. 생리학적인 변화는 대조군과 처리군에서 혈림프단백질 함량을 측정하여 비교하였다. 혈림프단백질의 함량 변화는 대조군과 처리군에서 암·수 모두 유사한 양상을 나타내었다. 그러나 전반적인 함량의 변화는 처리군이 대조군에서 보다 낮은 경향을 나타냈다. 또한 methoprene을 처리한 유충은 그 유충기간이 정상 발생군보다 연장되었으며 7령의 수컷이 유도되었다. The morphological and physiological effects of the juvenile hormone mimics, methoprene on the larvae of Lymantria dispar were investigated. Morphological changes were observed in the columnar and goblet cells in the mid gut of the treated Lymantria dispar larvae. In the columnar cells, the amount of lipid droplets were extremely increased and the nucleus was enlarged and the endoplasmic reticulum assumed the vaculoe-like configuration. Microvilli on the cell surface, however, were mostly preserved intact. In the goblet cells, the mitochondria-filled cytoplasmic projections were completely disorganized and the numerous fragments(or swirled membrane bodies) of plasma membrane were discharged into the goblet cavity. The protein concentrations of hemolymph of the normal and treated larvae were measured to determine the physiological effects of methoprene. The similar pattern of changes in protein concentrations of hemolymph was observed throughout the developments of the male and female larvae of two groups. The overall protein concentration of the treated larvae was lower than that of the normal larvae. It was found that the methoprene prolonged the larval stage and induced the male 7th instar larvae.

심근 경색증 환자의 죽상경화증 위험요인별 질병관련 지식과 건강행위 이행

정혜선 성인간호학회 2001 성인간호학회지 Vol.13 No.4

Purpose: This study purposed to examine the disease-related knowledge level and compliance with mood health behavior in patients with myocardial infarction according to the atherosclerotic risk factors . Method: The subjects consisted of 72 patients with myocardial infarction and the data were collected by interviewing the subjects with questionnaires and reviewing their medical records from September. 15. 1999 to July 31, 2000. Data were analyzed using the SAS program. Results: 1) With regard to atherosclerotic risk factors: of the subjects, 91.7% lacked regular exercise, followed by smoking (61.1%). 2) The average knowledge score of the patients was 19.7 and the average compliance score was 53.9. 3) There were no significant differences in the total knowledge scores according to the patients' atherosclerotic risk factors. 4) Non-diabetics were significantly higher in knowledge scores on domain of risk factors than the diabetics. 5) The overweight patients were significantly higher in knowledge score on domain of nature of disease than the normal-weight patients. 6) The total compliance stores of the non-smokers were significantly higher than those of the smokers. 7) The total compliance scores of the patients who do regular exercise were significantly higher than those of the patients who forgo regular exercise. 8) The non-smokers were significantly higher in compliance scores on domain of diet than the smokers. 9) The diabetic patients were significantly higher in compliance scores on domain of smoking cessation than the non-diabetics. 10) Patients who do regular exercise were significantly higher in compliance scores on other domains than the patients who forgo regular exercise. Conclusion : According to the above findings, it can be concluded that intensive nursing care and education should be provided to patients who have atherosclerotic risk factors such as smoking. hypertension, diabetes mellitus, lack of exercise, over weight, or hypercholesterolemia to increase disease related knowledge level and to improve compliance with good health behavior.

PPAR-γ작용약에 관한 3D-QSAR 연구

이혜선,박경래 충남대학교 약학대학 의약품개발연구소 2005 藥學論文集 Vol.20 No.-

The 3D-QSAR analysis with N-(2-benzophenyl)-L-tyrosine derivatives was conducted by Comparative Molecular Field Analysis(CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA). Two models yield the leave-one-out cross-validated correlation coefficient q² values of 0.62 and 0.56, and the conventional correlation coefficient r² values of 0.92 and 0.86, respectively. The achievement of higher q² and r² values of CoMFA model indicates the significance of correlation of steric and electrostatic fields with biological activities. The contour maps obtained from both CoMFA and CoMSIA studies were interpreted with respect to the binding site of the receptor. The quality of CoMSIA model is slightly lower than that of CoMFA in terms of q² and r² values. The models obtained from the present study can be useful for the development of new compounds with a more improved activity.

복숭아(Prunus persica) 葯培養에 依한 Callus 誘起

申熙錫 충남대학교 농업과학연구소 1977 農業技術硏究報告 Vol.4 No.2

In order to establish the effective method of producing calluses of Prunus persica, anthers were cultured on Nitsch's medium supplemented with combinations of several growth regulators. Anthers of tetrad stage were preserved in the refrigerator at 4℃ for 50∼50 days. Calluses were embeded on the Murashige and Skoog's medium supplemented with multiplicate and differentiate the calluses. Changes of anther color, callus formation, and proliferation of haploid callus were observed under the different medium conditions. The results obtained were summarized as fellows: 1) The cultured anthers were turned dark brown 2∼6days after were explanted anthers into the medium. 2) The anthers which were not changed in color were observed more frequently in the medium not added the growth regulators. 3) Calluses were induced from anthers which were turned dark brown and liberated from the anther slit. 4) BA. was very effective to induce calluses and to form the chlorophyll. The medium supplied with BA 0.5ppm were best to induced calluses. 5) The best medium supplied with BA 0.5ppm+IAA or 2.4-D were best to proliferation of calluses. 6) The medium was adjusted to pH 4.5 and supplied with 250mg/ℓ of CaCl_2·2H_2O were induced calluses from anthers.

축우사료의 에너지가 측정을 위한 in vitro방법의 검정

김효근 건국대학교 1991 대학원 학술논문집 Vol.34 No.-

This experiments were conducted to test the equations of Gas Test to predict in vivo metabolisable and net enengy values for ruminant feedstuffs. The feedstuffs for experiment were 20 compounds and 19 forages. The results obtained are as follows ; 1.The prediction error(PE%) of equations to evaluate ME valus of compound was 0.92∼1.35%, and PE% of equations for NEI was 1.10∼1.71% 2.For forages, PE% of ME equations was 0.98∼1.39% and that of NEI equations was 1.25∼1.72%