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홍윤철,임현술,하은희,정규철,조희숙,박혜숙,이용애 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4
Health Risk Appraisal(HRA) is usually defined as a process by which we expect of individual's chances of death or acquiring specific diseases within a defined period of time. The concept of worksite as an area of health maintenance and promotion is newly developing. Our movement for health promotion of employees has been increasingly known in the worksite. The aim of this study is to develop health risk appraisal tools about health promotion at the worksite for employees. We performed this study by two steps; one step was to develop a HRA questionnaire of worksites in Korea, another was to evaluate the reliability of the questionnaire. For developing HRA questionnaire, we reviewed scientific examples at first, and then weighted the score by delphi. To evaluate the reliability of developed questionnaire, we carried out survey by test-retest method. A total of 131 employees completed HRA questionnaire on two times. The results are as follows. The total score of health risk in unhealthy workers was higher than that of healthy workers. The range of test-retest reliability of responses to the questionnaire was 0.57-0.94. Therefore it seems that this questionnaire was very suitable to assess the health behavior of workers. In conclusion, the developed HRA questionnaire can be used as a tool for evaluating health behavior and for providing health counseling materials.
유윤종,류제천,임희대 忠南大學校 産業技術硏究所 2003 산업기술연구논문집 Vol.18 No.2
In this study, 1/8 model tests were carried out to understand the properties of the deep foundation and reinforced deep foundation. Also, carried out tests, divided into weathered rock and soft rock. The results of this study are summarized as follows; When piles is reinforced, reinforcing effect of soft rock is 1l-l2% and weathered rock is 233%. In the side load tests of weathered rock, reinforced effect was 223%. From the comparative study, the reinforced piles have enough reinforcing effect. Though some difference existed by foundations, reinforcing effect is reliable. Therefore reinforced deep foundation is profitable in the configuration of the earth.
건강증진학교 모형개발 : Based on Health Center of University 대형 보건소 활동을 중심으로
하은희,조희숙,윤영옥,강명근 韓國學校保健學會 2001 韓國學校保健學會誌 Vol.14 No.1
Objectives: The purpose of this study is to develop a health-promoting program centered on the university-health center and to provide a developed program for students and faculties. Methods: A survey was conducted of 719 female students and 238 faculties concerning their health-promoting programs. Based on the results of the survey, we developed programs that could be applied to students and faculties. After operating the programs, we developed further models by evaluating the effectiveness and satisfaction. Conclusions: We selected a comprehensive health-promoting program that included weight control, preventive inoculation, sex education and control of disease based on repsective needs. We also applied programs developed through collaboration with other departments from September 1998 to August, 1999. Users of the preventive inoculation-program increased by one point five during the year. Also, participants were generally satisfied with the weight control program and succeeded in reducing weight We hope that we can set up this program and expand it by developing various other projects in Korea. Key Words: Modeling, Health-Promoting School, Health Center of University
정규철,이용애,홍윤철,조희숙,박혜숙,임현술,하은희 이화여자대학교 환경문제연구소 1998 이화환경연구 Vol.2 No.-
Health Risk Appraisal(HRA) is usually defined as a process by which we expect of individual's chances of acquiring specific diseases within a defined period of time. The concept of worksite as an area of health maintenance and promotion is newly developing. Our movement for health promotion of employees has been increasingly known in the worksite. The aim of this study is to develop health risk appraisal tools about health promotion at the worksite for employees. We performed this study by two steps: one step was to develop a HRA questionnaire of worksites in Korea, another was to evaluate the reliability of the questionnaire. For developing HRA questionnaire, we reviewed scientific examples at first, and then weighted the score by delphi. To evaluate the reliability of developed questionnaire, we carried out survey by test-retest method. A total of 131 employees completed HRA questionnaire on two times. The results are as follows. The total score of health risk in unhealthy workers was higher than that of healthy workers. The range of test-retest reliability of responses to the questionnaire was 0.57-0.94. Therefore it seems that this questionnaire was very suitable to assess the health behavior of workers. In conclusion, the developed HRA questionnaire can be used as a tool for evaluating health behavior and for providing health counseling materials.
좌측 전대뇌동맥 영역의 뇌경색 후 발생한 초피질성 혼합 실어증 1예
심미섭,이연수,김은희,이인숙,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.1
We present a case of transcortical mixed aphasia (TMA) presumably caused by left anterior cerebral artery infarction. A 53-year-old, right-handed woman suddenly developed speech disturbance and abnormal behavior. Her spontaneous speech was remarkably reduced to almost mutistic state and objective naming, comprehension, reading and writing were severely impaired. However, repetition of phonemes and sentences were fully preserved. She showed echolalia and completion phenomenon, which prompted us to make a diagnosis of TMA. Although the lesion was confined to extrasylvian area on MRI, SPECT demonstrated diminished blood flow left perisylvian cortices suggestive of functional isolation of speech area. In spite of her echolalic repetition, she couldn't repeat affective prosody, presumably, because of the left anterior corpus callosal lesion. Treatment with bromocriptine, a dopamine agonist helped her recovery of behavioral changes, namely abulia or akinetic mutism consisitent with mesial frontal syndrome.
Yun, Cheol-Heui,Son, Chang Gue,Chung, Dae Kyun,Han, Seung Hyun 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.24 No.-
Chlorophyllin (CHL) is a chlorophyll derivative with anticarcinogen and antioxidant activities. Despite clinical importance of CHL as a potential therapeutics for treating cancer patients, little is known about the immunological properties of CHL. In the present study, we investigated the effect of CHL on the activation of murine splenocytes stimulated with lipopolysaccharide (LPS). RT-PCR analysis showed that LPS-activated IFN-γ expression gradually declined by CHL treatment in a dose dependent manner while mRNA production of TNF-α, IL-2, and FasL was not changed. CHL also suppressed IL-12 production (p70, a heterodimer of p40 and p35) and the mRNA expression of IL-12 p40 and IL-12 receptors (both IL-12Rβ1 and IL-12Rβ2), which are involved in the induction of IFN-γ expression. Furthemore, an electrophoretic mobility shift assay showed that CHL inhibited DNA binding activity of NF-кB, STAT-3, and STAT-4 to their cognate DNA recognition motifs, all of which contribute to the IL-12-induced IFN-γ transcription. Exogenous addition of recombinant IL-12 abrogated the inhibitory effect of CHL on IFN-γ and its mRNA expression in LPS-activated splenocytes. Collectively, these results show that CHL inhibits IFN-γ production by LPS-stimulated splenic mononuclear cells due to down-regulation of IL-12 production. © 2005 Published by Elsevier B.V.