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        Large Steel Tank Fails and Rockets to Height of 30 meters - Rupture Disc Installed Incorrectly

        Hedlund, Frank H.,Selig, Robert S.,Kragh, Eva K. Occupational Safety and Health Research Institute 2016 Safety and health at work Vol.7 No.2

        At a brewery, the base plate-to-shell weld seam of a $90-m^3$ vertical cylindrical steel tank failed catastrophically. The 4 ton tank "took off" like a rocket leaving its contents behind, and landed on a van, crushing it. The top of the tank reached a height of 30 m. The internal overpressure responsible for the failure was an estimated 60 kPa. A rupture disc rated at < 50 kPa provided overpressure protection and thus prevented the tank from being covered by the European Pressure Equipment Directive. This safeguard failed and it was later discovered that the rupture disc had been installed upside down. The organizational root cause of this incident may be a fundamental lack of appreciation of the hazards of large volumes of low-pressure compressed air or gas. A contributing factor may be that the standard piping and instrumentation diagram (P&ID) symbol for a rupture disc may confuse and lead to incorrect installation. Compressed air systems are ubiquitous. The medium is not toxic or flammable. Such systems however, when operated at "slight overpressure" can store a great deal of energy and thus constitute a hazard that ought to be addressed by safety managers.

      • KCI등재

        Large Steel Tank Fails and Rockets to Height of 30 meters − Rupture Disc Installed Incorrectly

        Frank H. Hedlund,Robert S. Selig,Eva K. Kragh 한국산업안전보건공단 산업안전보건연구원 2016 Safety and health at work Vol.7 No.2

        At a brewery, the base plate-to-shell weld seam of a 90-m3 vertical cylindrical steel tank failed catastrophically. The 4 ton tank “took off” like a rocket leaving its contents behind, and landed on a van, crushing it. The top of the tank reached a height of 30 m. The internal overpressure responsible for the failure was an estimated 60 kPa. A rupture disc rated at < 50 kPa provided overpressure protection and thus prevented the tank from being covered by the European Pressure Equipment Directive. This safeguard failed and it was later discovered that the rupture disc had been installed upside down. The organizational root cause of this incident may be a fundamental lack of appreciation of the hazards of large volumes of low-pressure compressed air or gas. A contributing factor may be that the standard piping and instrumentation diagram (P&ID) symbol for a rupture disc may confuse and lead to incorrect installation. Compressed air systems are ubiquitous. The medium is not toxic or flammable. Such systems however, when operated at “slight overpressure” can store a great deal of energy and thus constitute a hazard that ought to be addressed by safety managers.

      • KCI등재

        A Typology of Esport Players

        David P. Hedlund 글로벌지식마케팅경영학회 2023 Journal of Global Sport Management Vol.8 No.2

        In recent years, esports have grown from a small number of local gaming activities undertaken by a few recreational participants to a multi-billion dollar industry with professional leagues, franchises, teams and players. While the industry has grown, our collective understanding of some of the most fundamental questions such as who plays esports and why, have received scant attention from academics. In an effort to further understand, profile and categorize players, the purpose of this research is to create a typology of esports players and to cross-validate previous research findings. Using hierarchical and k-clustering techniques, six psychographic factors (socialization, positive affect, competition, fantasy/escape, coping, pass/waste time) and additional demo-graphic and behavioral characteristics are used to create a typology of esports players. Based on a large, diverse and inter-national sample of respondents (n¼1165), five types of players, including (1) Competitive, (2) Casual, (3) Casual-Social, (4) Casual-Fun, and (5) Casual-Competitive esports players, are identified. In-depth examination and discussion of the five types of players are provided. The implications of this research suggest the importance of considering demographic, psychographic and behavioral characteristics when attempting to identify, understand and classify different types of esports players.

      • KCI등재

        Immune responses against autologous tumor and human papilloma virus in lymph nodes from patients with penile cancer

        Lu Zhang,A. Ali Zirakzadeh,Jesper Rosvall,Mats Hedlund,Ping Sheng Hu,Katrine Riklund,Amir Sherif,Ola Winqvist 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.1

        Purpose: Nearly half of penile cancers are related to human papillomavirus (HPV) infection. Investigations of tumor- and HPV-specific T cell reactivity in regional lymph nodes (LNs) from patients with penile cancer are warranted. Materials and Methods: In this study, single-cell suspensions from LNs and peripheral blood from 11 patients with penile cancer were stained with antibodies for lymphocyte markers and analyzed by fluorescence-activated cell sorting (FACS). DNA was extracted from the tumor tissue and HPV status was investigated by PCR. Results: T-cell reactivity against autologous tumor-extract and against the HPV-vaccine Gardasil® was tested by flow-cytometric assay of specific cell-mediated immune response in activated whole blood (FASCIA). CD4+/CD8+ ratios were significantly lower in HPV positive LNs (p<0.05). Immune responses to tumor extract assessed by blast transformation and expansion in vitro, of either CD4+ or CD8+ T-cells, were found in 9 of 13 LNs (69%). 5 of 6 tested patients demonstrated T cell recognition of tumor-associated antigen(s). In HPV-positive patients, dose-dependent T cell responses against L1 (late) HPV proteins (Gardasil vaccine) were demonstrated. Conclusions: LN-derived T cells from patients with penile cancer recognize tumor antigen(s) and in HPV-positive cases, there is a response against L1 (late) HPV proteins, being constituents of the Gardasil vaccine.

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