여성 관상동맥질환자의 동기요인이 건강행위에 미치는 영향 요인

이혜영,정경옥,김금자 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Background: Misconceptions exist that coronary artery disease(CAD) is a male dominant disease, although the leading cause of death due to heart disease in women increased 7.1% from 2001 to 2004 in Korea. Lack of motivational factors to health behavior change places women at risk for subsequent CAD events. Purpose: The purpose of this study was to investigate motivational factors to health behaviors for women with coronary artery disease. Methods: Structured questionnaires survey was carried out on a convenience sample of 81 adult women in a cammunity setting. The subjects were recruited for an interview at outpatient clinic in hospitals. The data were analyzed using descriptive statistics, Pearson correlation coefficient and stepwise multiple regressions. Results; There were significant correlations between motivational factors and health behaviors(r=.664). Stepwise multiple regression revealed that 57% of variance in health behaviors was explained by self-efficacy and perceived benefits among four motivation variables(F=54.438 p<.01). However, there were no significant predicting factors of perceived barriers and emotional salience among motivational factors to health behaviors. Self-efficacy contributed the greatest amount of variance in health behaviors(β=.585), followed by perceived benefits(β=.226). Conclusions: The results of the study indicate that self-efficacy was very important in predicting health behaviors for women with coronary artery disease. Thus it would be necessary to include motivational factors in designing rehabilitation program to practice and adherence health behaviors for women with coronary artery disease.

지역별 보건소 이용의 만족도에 관한 연구 : 경북지역을 중심으로

이혜영,정경옥,김금자 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Purpose: The purpose of this study was to investigate the satisfaction and utilization and awareness of health center and satisfaction's affecting factors. Methods: The subjects consisted of 292 adult at three health centers on middle size cities in Gyeong San Buk-Do. Data was collected from August 2006 to June 2007 using structured questionnaires. One-way ANOVA were used to test satisfaction of health centers, utilization and awareness of health center and Kruskal-Wallis and Scheffe's test were used to test recommendation of health center and Post Hoc multiple comparison by using SPSS 14.0 for windows. Results: The satisfaction of health centers for community dwellers was related to age, educational level and family income and the difference of satisfaction of health centers were in comfortable surroundings, satisfaction of facilities, generosity of staff members and full explanation. The utilization and awareness of health center were differ from community areas. Conclusions: Further studies need to be done to investigate additional effects of satisfaction of health centers for community dwellers and to investigate nursing approaches for community dwellers to improve their satisfaction of health centers.

스프렌딜 지속정(펠로디핀 5㎎)에 대한 스타핀 지속정의 생물학적동등성

조혜영,강현아,이석,백승희,박은자,최후균,문재동,이용복 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.4

Felodipine is a calcium antagonist that lowers blood pressure by reducing peripheral resistance by means of a direct, selective action on smooth muscle in arterial resistance vessels. Furthermore, it have been approved for the effective in angina pectoris and cardiac failure. The purpose of the present study was to evaluate the bioequivalence of two felodipine extended release (ER) tablets, Splendil (YuHan Corporation) and Stapin (Hana Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). THe felodipine release from the two felodipine formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method at pH 6.5 buffer solution. Twenty six healthy male subjects, 22.73±1.78 years in age and 66.66±7.28 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After two tablets containing 5 ㎎ as felodipine were orally administered, blood sample was taken at predetermined time intervals and the concentrations of felodipine in serum were determined using column-switching HPLC method with UV detector. The dissolution profiles of two formulations were similar at pH 6.5 buffer solution. Besides, the pharmacokinetic parameters such as AUG_(t), C_(max) and T_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t) and C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Splendil were 2.53%, 1.32% and 18.32% for AUC_(t), C_(max) and T_(mzx), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.86)∼log(1.20) and long(0.89)∼long(1.23) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating Stapin ER tablet and Splendil ER tablet are bioequivalent.

리스페달 정(리스페리돈 2㎎)에 대한 리스펜 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,박찬호,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two risperidone tablets, Risperdal (Janssen Korea Co., Ltd) and Rispen (Myung In Pharm. Co., Ltd), according to the guidelines of Korea Food and Drug Administration (KFDA). The risperione release from the two risperidone formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with various of dissolution media (pH 1.2, 4.0, 6.8 butter solution and water). Twenty four healthy male subjects, 23.33±2.10 years in age and 69.24±8.05 kg in body weight, were divided into two groups and a randomized 2×2 crossover study was employed. After one tablet containing 2 ㎎ as risperidone was orally administered, blood was taken at predetermined time intervals and the concentration of risperidone in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Risperdal were 0.20, -1.29 and -11.09% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.90)∼log(1.03) and log(0.84)∼log(1.09) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Rispen tablet and Risperdal tablet were bioequivalent.

아마릴 정(글리메피리드 2㎎)에 대한 글리메드 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,김세미,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two glimepiride tables, Amaryl^(?)(Handok/Aventis Pharm. Co., Ltd.) and Glimed (Kuhn Ⅱ Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The glimepiride release from the two glimepiride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solution, water and blend of PSB 80 into each dissolution medium). Twenty six healthy male subjects, 22.65±2.19 years in age and 66.55±8.85 kg in body weight, were divided into two groups and randomized 2×2 cross-over study was employed. After one tablet containing 2 ㎎ as glimepiride was orally administered, blood was taken at predetermined time intervals and the concentrations of glimepiride in serum were determined using HPLC method with UV detctor. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Amaryl were -3.70, -8.28 and 0.61% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25)(e.g., log(0.84)∼log(1.04) and log(0.82)∼log(1.03) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Glimed tablet and Amaryl tablet were bioequivalent.

비유피-4 정(염산프로피베린 20㎎)에 대한 건일염산프로피베린 정의 생물학적동등성

조혜영,박은자,강현아,백승희,김세미,박찬호,오인준,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

The purpose of the present study was to evaluate the bioequivalence of two propiverine hydrochloride tablets. BUP-4 (Jeil Pharm. Co., Ltd.) and Kuhnil Propiverine Hydrochloride (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The propiverine release from the two propiverine hydrochloride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solutions, water and blend of polysorbate 80 into pH 6.8). Twenty six healthy male subjects, 23.73 ± 2.79 years in age and 67.04 ± 7.93 kg in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 20 mg as propiverine hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of propiverine in serum were determined using HPLC method with UV detector. The dis-solution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC" C _(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC, C_(max), and untransformed T_(max). The results showed that the differences between two formulations based on the BUP-4 were 0.17%, 7.98% and 4.55% for AUC,, C_(max), and respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically trans-formed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.88)-log(l .12) and log(0.90)-log(l.15) for AUC, and _(max), respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kuhnil Propiverine Hydrochloride tablet was bioequivalent to BUP-4 tablet.

체육 학부생의 진로선택과 취업준비

전혜자 順天鄕大學校 學生生活硏究所 1997 學生生活硏究 Vol.6 No.-

The purpose of this study was to analyze the planning of the course and the preparation of the job for the freshmen, sophomores, and juniors in Soonchunhyang University, and to obtain the fundamental data for guiding the job based on the survey. The subjects were 163 students(male: 99, female: 64) who were attending the division of physical education. For analyzing the data, the frequency and percentage were used. The results were as follows; (a) The subject appropriately selected their majors and the degree of their satisfaction on the campus life was high, and (b) they had difficulties to choose their jobs.

수술 후 Diazepam에 의해 Sedation된 환자에서 Naloxone이 환기능에 미치는 영향에 관한 연구

김혜자 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.2

One group, in 6 matte and 4 female undergoing the general anesthesia, naloxone (0.8mg) was bolus injected at immediate postoperative period. The respiratory rate, tidal volume, minute ventilation and arterial blood gases were measured at 15 minute after naloxone on the ventilation. The injection of naloxone resulted in following changes; 1. Respiratory rate was significantly decreased (P<O. 0 1). 2. Arterial carbon dioxide tension was decreased remarkably. The remarkable decrease of respiratory rate and slightly increase minute ventilation following naloxone injection was considered to decrease arterial carbon dioxide tension significantly. In the study, it is concluded that the administration of naloxone may be one of the ways to improve the postoperative ventilating impairment often complicated by hypoxemia.

8주간 유산소운동이 혈중전해질 농도와 혈중pH에 미치는 영향

현송자,석혜경,김귀백 東亞大學校附設스포츠科學硏究所 2001 스포츠科學硏究論文集 Vol.19 No.-

The purpose of this study is to analyze the electrolyte such as blood ph, Na^(+), K^(+), Ca^(2+), Mg^(2+), etc on the each stage of pre-exercise, post-exercise, each 5 minute-recovery, 10 minute-recovery & 30 minute- recovery after exercise. For this experiment, 14 male students at the department of athletics in B Information Technology college in Busan was classified into each 7 exercise group and 7 non-exercise group, and after training them on the intensity of 60%HRmax of each subject 3 period a week for 8 consecutive weeks, the experiment was carried out with the same condition as training manner in treadmill. The results of this study are as follows. 1. Change of Blood Ph Through Aerobic Exercise In exercise group and non-exercise group, there was no particular change in Blood Ph between rest before training & the rest after 8 week- training according to t test. In case of exercise group, after 8 week-training blood ph value was significantly decreased, and at the 30minute-recovery after exercise, ph value was recovered to the degree of rest (p<.001). In case of non-exercise group, blood ph indicated significant change as the similar tendency showed in exercise group, at 10 minute-recovery after exercise, blood ph was recovered to the degree of rest. (p<.001). The change of ph by period between exercise group and non-exercise group was not significantly different. 2. Change of Blood Electrolyte Through Aerobic Exercise 1) Change of blood Na+ through aerobic exercise In exercise group and non-exercise group, the change of Na^(+) between the rest before training and the rest after training was not significantly different according to the result of t test. In case of exercise group, after performing 8 week-training, Na^(+) value was significantly increased, and at 10 minute-recovery after exercise, Na^(+) value began to recover into the value in rest, and after 30 minute-recovery after exercise, Na^(+) value was recovered into the degree of rest (p<.05). In case of the change of Na^(+) in non exercise group, after exercise, Na' value was significantly increased in comparison with rest period, and at 5 minutes after exercise, it was recovered into the degree of rest. (p<.01). The change of Na^(+) by period between exercise group and non-exercise group was not significantly different. 2) Change of Blood K^(+) through aerobic exercise In exercise group and non-exercise group, the change of K^(+) in rest before training and the rest after training was indicated that there was no significant difference according to t test. In case of exercise group, after 8 week training, K^(+) value was significantly increased, and at 5 minute-recovery after exercise, K^(+) value was recovered into the value in rest (p<.05). K^(+) in non-exercise group was not significantly changed. 3) Change of blood Ca^(+) through aerobic exercise In case of exercise group, the change of Ca^(+) in rest before training and the rest after training was not significantly different according to the result of t test. In case of non-exercise group, the change of Ca^(+) in rest before training and the rest after training was significantly different according to the result of t test (p<.05). In case of exercise group, after 8 week-training, Ca^(+) value was significantly increased, and at 5 minute- ecovery after exercise, Ca^(+) value began to recover into the degree of rest, and after 30 minute-recovery after exercise, Ca^(+) value was recovered to the degree of rest (p<.01). In case of the change of Ca^(+) in non-exercise group, after training, Ca^(+) value was significantly increased in comparison with rest period, and at 30 minute-recovery after exercise, Ca^(+) value was recovered into the degree of rest. (p<.001). In case of the change of Ca^(+) by period between exercise group and non-exercise group, after exercise and at 5 minutes recovery after exercise, the change of Ca^(+) in non-exercise group is higher than that of exercise group (p<.01). 4) Change of blood Mgt^(2+) through aerobic exercise In exercise group and non-exercise group, the change of Mg^(2+) between rest before training and the rest after training was not significantly different according to the result of t test. In both cases of exercise group and non-exercise group, after 8 week- raining, the change of Mg^(2+) was not significantly different. The change of Mg^(2+) by period between exercise group and non-exercise group, after exercise, the change of Mg^(2+) of non-exercise group was higher than that of exercise group (p<.01). 3. Correlation Between Blood Ph and Electolyte Through Aerobic Exercise In performance of 8 week aerobic training, the result of correlation analysis between blood ph and electrolyte in pre-exercise, post-exercise, each 5 minute, 10 minutes, 30 minutes-recovery after exercise showed that in case of Na^(+), K^(+), Mg^(2+) did not have significant correlation, but in case of Ca^(2+), it showed significant negative correlation in pre-exercise and at 10 minute- recovery after exercise. (p<.05).

Sons and Lever와 Feminism

姜惠子 배화여자대학 1985 培花論叢 Vol.4 No.-

Lawrence's works have been a focus for the discussion of sexual relationships and roles. In discussing Lawrence we must, sooner or later, tackle the issue of "Lawrence and feminism". From the very first Murry attacked Lawrence's feminism in Son of Woman. Anais Nin praised for Lawrence's sensitive portrayals of femininity in her An Unprofessional Study. Murry and Nin's criticism predict much subsequent feminist criticism including Simone de Beauvoir's The Second Sex and Kate Millett's Sexual Politics. Feminist criticism is still in its infancy, but the documentation of women's history is well established and can help to provide a new basis for literary analysis. Lawrence's literary career spanned one of the most important periods in that history. In Sons and Lovers he describes the "Advanced Women" of those periods through Mrs. Morel, Miriam, and Clara. These three female characters should not be stereotyped as we have often seen in Lawrence criticisms, such as Mrs, Morel-destructive woman, Miriam-spiritual lover, and Clara-possessive, sensual lover. Feminist criticism re-examine female characters, female ideals, and female themes. In this study an attempt is made to examine Paul's self-sustaining ego and mother-obsession. Mrs. Morel, Miriam and Clara are re-examined as women who exist in Paul's orbit and support the son of a coal miner to rise above the circumstances of his birth and become a great artist.