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石鍾聲,朴蕙瓊,李承薰 최신의학사 1975 最新醫學 Vol.18 No.5
The role of Pseudomonas aeruginosa in human diseases has received increasing attention in recent years. There is considerable evidence that intestinal Gram negative bacillary infections are occuring with greater frequency. Among these bacilli, Ps. "aeruginosa is so notoriously resistant to many antibiotics that it occupies an almost unique position. 903 strains of Ps. aeruginosa were isolated from various clinical materials at Seoul National University Hospital during the period of January 1st, 1970 and December 31. 1974 and clinico-bacteriological studies were made. The results were summarized as follow. 1. Clinical materials, from which Ps. aeruginosa were isolated, were Pus 448, Urine 151, Sputum 142, Throat swab 34, Blood 33, Bile 20, Bronchial aspiration 10, Pleural fluid 8, Stool 8, Spinal fluid 4, Vaginal discharge 2, Bone irrigation 2 and Ascitic fluid 1, respectively. 2. The clinical departments and the percentage of strain numbers from various materials submitted from the departments: General surgery 30. 0%, Internal medicine 26. 1%, Urology 13.6%, Orthopedic surgery &4%, Chest surgery 6.5%, Pediatrics 4.2%, Neuro surgery 3.4%, Obstetrics and Gynecology 3.0%, E.N.T. 2.6% and other departments 2.2%, respectively. 3. The cases of mixed infection with Ps. aeruginosa in a clinical materials were 23.6%. 4. The bacterial species and number of strains isolated with Ps. aeruginosa were klebsiella aerogenes 61, Coagulase positive staphylococcus 51, Escherichia coli 35, a-hemolytic streptococcus 18, Alcaligenes faecalis 16, Coagulase negative staphylooccus 11, Proteus mirabilis 10, Paracolon bacilli 9, respectively. 5. The percentage of resistant straims of Ps. aeruginosa to various antibiotics were as follow: Gentamycin 6.6%, Colimycin 33. 1%, Streptomycin 7& 1%, Kanamycin 94.2%, Chloramphenicol 94.4 %, Oxytetracyclin 94.9%, Lincomycin 9&4%, Penicillin 99.9%, Ampicillin 99.9%, and Cloxacillin 100%.
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Polytertrafluoroethylene의 직경에 따른 신생내피의 조직학적 변화에 대한 실험적 연구
박해일,이광석 고려대학교 의과대학 1998 고려대 의대 잡지 Vol.35 No.2
In synthetic arterial grafts the regeneration and proliferation on the inner surface of graft is a part of the normal healing process. However, there are controversies in the source of these cells and the pattern of proliferation. Many investigators have suggested that endothelium might be derived from arterial sources at the ends of grafts, capillaries growing through the graft matrix from the outside, and endothelial cells can circulate in the blood and settle onto the luminal surface. The purpose of this study was to investigate the patency rates and the histologic findings of neoendothelialization according to the diameter of polytetrafluoroethylene(PTFE) which is the most widely used for synthetic graft. Ten mongrel dogs, weighing 20 to 25kg, were used for this study. Under the operating microscope, all grafts were implanted in both femoral arteries of dogs by interrupted end-to-end microanastomosis. They were divided into two groups according to the diameter of implanted PTFE. Each group comprised five dogs. The lengths of implanted PTFE were 20mm in both groups. All implanted grafts were 25㎛ in fibril length and 0.39mm in wall thickness. The internal diameter of graft in group Ⅰ was 3mm and that of graft in group Ⅱ was 5mm. Two grafts of one dog per group were harvested at 1, 2, 4, 8, and 12 weeks after implantation respectively. All PTFE grafts were observed for patency rates and the histologic findings with light microscope and scanning electron microscope. The results obtained were as follows : 1. The patency rate was higher when the diameter of implanted PTFE was larger than that of recipient vessel, and the patency rate in grafts without infection was higer than that in grafts with infection. 2. Light microscopically, in group Ⅰ, a few cells of neointima is noted at the end of the inner surface of PTFE at 1 week after implantation and the histologic findings could not be observed due to occlusion of grafts at 2, 4, 8, and 12 weeks after implantation. In group Ⅱ, the neointimal lining is advanced across the anastomosis at 1 week after implantation and the histologic findings could not be observed due to occlusion of grafts at 2 and 8 weeks after implantation. At 4 weeks after implantation, neointimal lining was more advanced to the midportion of implanted PTFE. At 12 weeks after implantation, the entire inner surface of implanted PTFE was lined completely by neointima and subintimal tissue. 3. Scanning electron microscopically, in group Ⅰ, the inner surface of implanted PTFE was lined by amorphous fibrin layer at anastomosis site at 1 week after implantationin and the histologic findings could not be observed due to occlusion of grafts at 2, 4, 8, and 12 weeks after implantation. The histologic findings of group Ⅱ were similar to those of group Ⅰ at 1 week after implantation and could not be observed due to occlusion of graft at 2 weeks after implantation. At 4 weeks after implantation, flat layer like normal endothelium was noted at anastomosis site. At 8 weeks after implantation, flat neointima was noted in the midportion of implanted PTFE. However, the inner surface of implanted PTFE was still noted at 12 weeks after implantation. 4. Neoendothelium was noted only in the patent cases with neointimal covering of the inner surface of PTFE. In conclusion, at 1 week after implantation neoendothelium started to grow from both anastomoses and at 8 weeks neoendothelium was formed in the entire inner surface of implanted PTFE. Because PTFE is not elastic like normal vessel, PTFE with larger diameter than that of recipient vessel is recommended as the grafts fot implantation.
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工業敎育大學 工業化學敎育科의 敎科課程 改善에 관한 硏究
송해영,홍원표,맹기석,윤석호,노재성,강용 충남대학교 공업교육연구소 1983 論文集 Vol.6 No.2(A)
The methods for the improvements of curriculum of the Department of Industrial Chemistry Education were examined in some detail discussing the following items; 1) Comparison and analysis of the new curriculum with the old of the Department of Chemical Industry in technical high school. 2) Examination of the current curriculum of the Department of Industrial Chemistry Education in Industrial Education College. 3) Suggestion of the improved curriculum suitable for the students in the Department of Industrial Chemistry Education.
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衣服 構成에 관한 硏究(Ⅰ) : Dress Design의 기초 Basic thneory of dress design
朴惠淑 공주대학교 사범대학 과학교육연구소 1970 과학교육연구 Vol.3 No.1
Design of modern dress is making much progress and transfiguration on a mission of beautification and practical utilization of clothing habits, dress design, a synthetic art of sense and technic, should have dynamic expressions based on personal movements, ands. many difficult problems come up in dress designing. such being the case, thereseorcher came to have the necessity that he should analyse and study basicprinciples of dress design in a theoretical viewpoint uninfluenced by fashion and comes to the conclusion as fonows. 1) Design can be practised by everyone can make creation with deeper study on basie knowledge of the princiole of design. 2) A designer, whose basic principle is to find out the whereabouts of beauty, showd try to discover and make study of beauty in the surrounding nature and develop it. 3) The three requisites for dress design are color, form and stuff, and the synthetie harmony of the tree requisites should match with the body. 4) Silhouette with well-matched design should be furnished with not only visual beauty but also functional convenience for wearing.
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조해용,정석영,김명한,조창용,이제훈,서정 한국레이저가공학회 2001 한국레이저가공학회지 Vol.4 No.1
Simulation on the electron beam welding of Al 2219 alloy was carried out by using commercial FEM code MARC, which encounters moving heat sources. Due to axisymmetry of geometry, a half of the cylinder was simulated. A coupled thermo-mechanical analysis was carried out and subroutine for heat flux was substituted in the program. The material properties such as specific heat, heat transfer coefficient and thermal expansion coefficient were given as a function of temperature and the latent heat associated with a given temperature range is considered. As a result, the proper beam power is 60kVX60mA and welding speed is 1~1.5 m/min. The residual stress in the heat-affected zone as well as the fusion zone does not increase. It is necessary to use jigs for preventing distortion of cylinder and improving weld quality.
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조석현,박해근 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1
The influence of environmental temperature on the acid base balance of frog(Rana Temporaria Chosenica) blood was investigated at 25℃ all the year round. pH of blood was measured by means of Artrup method and Sigaard- Anderson's nomogram using pH meter(Corning) and tonometer. Buffer value, actual bicarbonate concentration and OH^-/H^+ ratio were calculatedd by the measure buffer line, pH and CO2 gas tension which was used(low CO_2 was 4-5% and high C0_2 was 8-9% balanced with 0_2). Results obtained are as follows: 1. Buffer line was shift to the upper and-right side during winter season and the differences was statistically significant. 2. Buffer value was higher during winter season than summer value and the difference was significan (p<0.001). 3. The actual blood pH was 7.42±0.01 in September and 7.78±0.03 in January. Generally the pH was higher during winter season than that of summer. The difference between two seasons was statistically significant(p<0.05). 4. The blood PCO_2 value has a seasonal changes with low PC0_2 during winter season and the differences were statistically significant. 5. The plasma bicarbonate concentration was 17.00±1.07mM/L in September and the value were decreased with cold weather of 12.33±1.29mM/L in January. Seasonal changes were significantly different(p<0.05). It is concluded from this findings that the acid-base changes of blood in frog were related to the temperature of living habitat and the corresponding changes in the tissue energy store and buffers.
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