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      • 저수준 문자 영상의 인식에 관한 연구

        공용해,김명숙,최인석 순천향대학교 부설 산업기술연구소 1999 순천향 산업기술연구소논문집 Vol.5 No.2

        Low quality character images include a lot of variousness and noises, so the use of a single classifier is difficult to achieve a high recognition performance. For this, we experimented various feature extraction methods suitable for low quality images and constructed a classifier-pair that uses two complementary features. The experimental result using this classifier-pair was very effective for the recognition of low quality character images.

      • KCI등재

        기초간호자연과학의 병태생리학, 병원미생물, 약물의 기전과 효과 내용별 필요도에 대한 연구

        최명애,변영순,서영숙,황애란,김희승,홍해숙,박미정,최스미,이경숙,서화숙,신기수 대한기초간호자연과학회 2000 Journal of korean biological nursing science Vol.2 No.1

        The purpose of this study was to define the content of the requisite knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs needed for clinical knowledge for nursing practice. Contents of knowledge on pathological physiology, clinical microbiology, and mechanisms and effects of drugs were constructed from syllabus of basic nursing subjects in 4 colleges of nursing, and textbooks. The degree of need of 72 items was measured with a 4 point scale. The subjects of this study were college-graduated 136 nurses from seven university hospitals in Seoul and three in Chonnam Province, Kyungbook Province, and Inchon. They have been working at internal medicine ward, surgical ward, intensive care unit, obstetrics and gynecology ward, pediatrics ward, opthalmology ward, ear, nose, and throat ward, emergency room, rehabilitation ward, cancer ward, and hospice ward. The results were as follows : 1. The highest scored items of the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs necessary for nursing practice were side effects of drugs, anticoagulants, mechanisms of drugs, antihypertensive drugs, tolerance and addiction of drugs, interactions among drugs, hospital infection in the order of importance. The lowest scored item was structure of microrganisms. 2. The highest order of need according to unit was repair in tissue injury unit, definition·etiology·classification of inflammation in inflammation unit, trasplantation and immunologic response in alterations in immunity unit, thrombus and thrombosis in disorders of cardiovascular function unit, gene disorders in genetic disorders unit, hospital infection in infection unit, virus in microrganisms unit, side reactions of drugs in introduction unit, anticonvulsants in drugs for central nervous system unit, local anesthesia in anesthesia unit, anticoagulants in drugs for cardiovascular system unit, anti-inflammatory drugs in antibiotics unit, anti-ulcer drugs in drugs for digestive system unit, and bronchodilators in drugs for respiratory system unit. 3. The common content of the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs needed for all clinical areas in nursing were side effects of drugs, anticoagulants, interactions among drugs, and hospital infection. However, the degree of need of each pathological physiology, clinical microbiology, and mechanisms and effects of drugs was different depending on clinical areas. 4. Significant differences in the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs necessary for nursing practice such as tissue changes due to injurious stimuli, degenerative changes of tissue, alterations in metabolism of carbohydrates, ischemia, hyperemia and congestion, hospital infection, structure of microorganism, classification of microorganism, bacteria, virus, antidepressants, antipsychotic drugs, antiemetic drugs, antiparkinsonism drugs, antianxiety drugs, antibiotics, tuberculostatics, antiviral drugs, antifungal drugs, parasiticides, antiulcer drugs, antidiarrheais, and anti constipation drugs were shown according to the work area. 5. Significant differences in the knowledge of pathophysiology, clinical microbiology, and mechanisms and effects of drugs necessary for nursing practice such as transplantation and immunologic response, alterations in the metabolism of uric acid, structure of microorganism, classification of microorganism, immunosuppresants, drugs for congestive heart failure were demonstrated according to the duration of work. Based on these findings, all the 72 items constructed by Korean Academic Society of Basic Nursing Science should be included as contents of the knowledge of pathophysiology, clinical microbiology. and mechanisms and effects of drugs

      • Polarimeter를 이용한 Unnatural Amino Acid 유도체의 선광도 측정

        박명숙,박해선,권순경 德成女子大學校 藥學硏究所 2001 藥學論文誌 Vol.12 No.1

        For the development of new COX-2 inhibitor, novel unnatural amino acids, key intermediates were synthesized through induction an arylsulfonyl group to 1-position, an aralkyl group to 4-position of 4-hydroxy L-proline. The 4-aralkyloxy-1-(4-tosyl)-L-prolines 5a-d were synthesized through N-tosylation, esterification, O-alkyl-(or aryl)ation, base-hydrolysis (deprotection of carboxylic acid) from 4-hydroxy-L-proline. The optical activity of unnatural amino acids were studied how the specific rotation was related with their structure. The optical rotation of unnatural amino acids were determined by polarimeter.

      • COX-2 Inhibitors를 위한 새로운 1,2-치환된 피롤리딘 유도체의 합성

        박명숙,신혜순 德成女子大學校 藥學硏究所 2000 藥學論文誌 Vol.11 No.1

        For the development of new COX-2 inhibitor, novel compounds were synthesized through induction an arylsulfony group to 1-position, an arylcarboxamidyl group to 2-position and an aralkyl group to 4-position of L-proline. The 4-aralkyloxy-1-(4-methylphenylsulfonyl)-L-prolines 5a-d were synthesized through N-tosylation, esterification, O-alkyl-(or aryl)ation, base-hydrolysis (deprotection of carboxylic acid) from 4-hydroxy-L-proline. Final 4-aralkyloxy-1-(4-methylphenylsulfonyl)-2-phenylcarboxamidyl-L-prolines 6a-d were synthesized through the condensation of aniline with 5a-d using DCC.

      • 과학 데이터 처리를 위한 질의어 표현

        이혜명,주해종,이시현 건국대학교 1997 대학원 학술논문집 Vol.44 No.-

        The multimedia dafabase system, which provides functionalities of storing, managing and querying the multimedia data, becomes the essential system software to support various newly emerging multimedia application such as speech, online hand-written character, electrocardiogram (ECG). Above all, particular processes are needed for manipulating scientific data, a kind of multimedia data, because data are massive and their sequent order must be kept. In this paper, it is proposed that a convenient user's query language, called SDQL(Scientific Data Query Language), to store scientific data into database. And SDQL is based on standard SQL-like syntax.

      • KCI등재

        스테로이드 치료 후 회복기의 규칙적인 운동이 쥐의 스테로이드 유발성 위축 뒷다리근에 미치는 영향

        최명애,변영순,황애란,김희승,홍해숙,최스미,서화숙,이경숙,박미정,신기수,안경주,이윤경,임지회 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.1

        This study was conducted to determine whether low intensity regular exercise following steroid treatment could attenuate steroid-induced muscle atrophy. Thirty-eight Sprague-Dawley rats weighing 165~175g were divided into six groups;control group(C), dexamethasone administration group(D), sedentary after normal saline administration group(C+Se), exercise after normal saline administration group(C+Ex), sedentary group after dexamethasone administration(D+Se), exercise group after dexamethasone administration(D+Ex). Either dexamethasone(5mg/kg) or normal saline was injected for 7days accordingly. Exercise was started at 10m/min on the 10?grade treadmill and gradually increased up to 15m/min by the 7th day for 60minutes/day(20min×3). The data were analyzed by Kruskal-Wallis test and Mann-Whitney U test using the SPSS WIN 9.0 program. Body weight, muscle weight and myofibrillar protein content of both plantaris and gastrocnemius, Type I, II muscle fiber cross-sectional area of plantaris, and Type II muscle fiber cross-sectional area of gastrocnemis in D group were significantly lower than those of C group(p<.05) respectively. Hindlimb muscle weight, myofibrillar protein content of both plantaris and gastrocnemius, Type I muscle fiber cross-sectional area of soleus and Type I, II muscle fiber cross-sectional area of plantaris in D+Ex group tended to increase compared to those of D+Se group. Myofibrillar protein content of both plantaris and gastrocnemius, Type I muscle fiber cross-sectional area of plantaris in D+Ex group tended to increase compared to those of C+Se group. Based on these results, it is suggested that regular low-intensity exercise during recovery period after steroid treatment might facilitate the recovery from steroid-induced muscle atrophy.

      • 조세경쟁이 지역경제의 성장과 분배에 미치는 효과분석

        지해명 한국산학경영학회 2003 산학경영연구 Vol.16 No.-

        현재 지방자치단체가 지방세를 탄력적으로 운용할 수 있도록 재정적 인센티브를 부여하자는 안이 대두되고 있다. 그렇지만 지방세의 변화가 지역경제의 순환구조를 왜곡할 수 있으며, 또한 지방자치단체간 조세경쟁 촉발 가능성이 있다는 이유로 그 제도의 실행이 순조롭지 않은 상황이다. CGE 모형의 의태분석 결과를 보면 지역에서 지방세 인하경쟁이 나타나면 공공부문의 비중이 작은 지역에서는 지역경제가 성장하는 한편 공공부문의 비중이 큰 지역은 경제침체가 초래된다. 따라서 지역간 경제력 격차가 확대되며, 학력별 소득분배를 악화시키게 된다. 조세인상 경쟁이 나타나면 지역간 경제력 격차의 축소 및 학력별 소득분배의 개선 가능성은 존재하지만 전반적인 경제침체가 초래된다. 이러한 분석에 근거하면 지자체의 입장도 설득력이 있으므로 정부는 이러한 폐해가 나타날 수 있다는 가능성을 수용해야 할 것이다. 따라서 국세권 일부의 지방이양 등 정책조합을 통하여 상충관계를 극복할 수 있는 방안을 마련해야 할 것인바. 간접세는 직접세 위주의 지방세보다 생산 부문에 유의한 효과를 주므로 지방자치단체가 경제성장에 탄력적으로 대응할 수 있는 수단이기 때문이다. The Korean government issues the policy that regional government mat change the regional tax rates for economic growth. On the ground that change in regional tax rate incurs the disturbance in regional economy and entails tax competition, regional government does not accept the proposal. The CGE simulation result shows that tax competition reveals the trade-off relation between efficiency, balanced national development, and equity. Thereby, the stance of regional government can be justified by the results. Therefore central government has to grope for some reconcile means that efficiency and equity can be harmonized. The proposal can be justified by the analyses.

      • KCI등재

        대학생들의 우울장애에 관한 연구 : 유병율, 위험요인, 자살행동 및 기능장애

        노명선,전홍진,이해우,이효정,한성구,함봉진 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5

        Objectives : The purpose of this study was to investigate the prevalence and correlates of major and minor depressive disorders in college students. Methods : A cross-sectional study was completed on a sample of 906 students (507 men and 399 women) with the self-administered form of Korean version of Mini International Neuropsychiatric Interview (K-MINI). Results : Estimated 12-month prevalence of major depressive disorder was 4.2% in men and 9.5% in women, and that of minor depressive disorder was 15.4% in men and 23.2% in women. The factors, 'female gender' and 'age of 20-21', were significantly associated with major depressive disorder. 'Poor adaptation to school' was significantly associated with major depressive disorder both in men and women, but 'poor interpersonal relationship' and 'history of school withdrawal' were associated only in men. Idea of self-injury and suicidal behaviors (suicidal ideation, plan and attempt) were significantly associated with major depressive disorder in women, but were not associated with minor depressive disorder. Conclusion : Major and minor depressive disorders are highly prevalent in the college students. Major depressive disorder was more associated with dysfunctions and suicidal behaviors than minor depressive disorder. Campus-based mental health service is needed for the high-risk students.

      • 당뇨병 환아의 당뇨캠프 프로그램 종료후 시간경과에 따른 우울,자기효능감,자기존중감의 변화

        최명애,유주화,한경자,안혜영 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.13 No.1

        The purpose of this study was to explore the effect of diabetic camp program on depression, self-efficacy and self-esteem of the juvenile diabetic patients who had participated diabetic camp program at Seoul and Kyung In area from August 5 to August 9, 1995. It was compared the change of depression, self efficacy and self-esteem right after participating the program, 6 and 12 month. Nursing staffs explained them how to respond to the questionnaire of depression, self-efficacy and self-esteem. The questionnaire of depression, self-efficacy and self-esteem was especially developed by both dibetes mellitus nurse specialist and pediatric nursing progessors for this study. Elementary school students are asked to response yes or no questionnarie. We asked the 5 lidert scale questionnaire for the both middle and high school students. Paired t-test was used to compare the difference right after the diabetic camp program, 6 and 12 month. Depression decreased right after participating the program, while self-esteem increased significantly following the program in elementary school students. And after the camp, there was o change in depression and self-esteem scores 6 and 12 month. There was no change in self-esteem and self-efficacy right after the camp, 6 and 12 month in middle and high school students. The result suggests that diabetic camp program could be the effective way to decrease depression and to increase self-efficacy and self-esteem, which has continued effect of diabetic camp program on depression, self-efficacy and self-esteem after 6 and 12 onth of the diabetic camp.

      • 학교차가 중·고등 학생의 학업성적 결정에 미치는 영향

        이해명 단국대학교 1999 論文集 Vol.34 No.-

        The object of this research is to examine the effect of 'school difference' on school attainment and the degree of the effects if the relationship between two factors is proved to be positive. The research was undertaken by following process: 1) investigating the effect of school difference on the entire target population: 2) examining how the school difference affect academic achievement and determine effects of different educational variables on academic achievement: 3) studying the degree of effects of school difference on individual school attainment. The target population for this research was 1735 students from 16 middle schools and 1619 students from 25 high schools respectively. For analysing the data collected from geographically well represented schools. I used co-efficency, F-test and regresional analysis as main analytical tools. The research results shows that there is no meaningful relationship between middle school student academic achievement and school difference. The degree of effect of above mentioned two factors was neglgible. Furthermore, for middle school students the school difference has no significant effect on the determinant structure of school attainment. Neverthless, this was not the case for the high school student. There was meaningful relationship between high school student academic achievement and school difference. The degree of positive relationship between academic achievement and school difference went up to 10%. For high school student, the school difference have accompanied with extra teaching for the positive shool attainment. In sum, the school difference had the significant effect on the determinant structure of high school student academic achievement The research has important implication for the equalization policy of the government: the equalization policy can be rationalised for he middle school student but not for the high school student considering its impact on school attainment. Knowing that the school difference has significant effect on the determinant structure of high school student academic student, the universal application of 'equalization policy' to the all secondary schools will may lead to the unexpected structural inefficiency of our education system.

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