자궁내 태아사망의 임상적 고찰

이권해,이정재,조현철,이석민,이임순,이해혁,김권대,이순곤,남계현 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Objective: This study was designed to evaluate diagnosis and complication, prognosis during clinical study of cases of intrauterine fetal death. Methods and materials: This is a clinical study of 56 cases of the intrauterine fetal death among 8064 deliveries at Seoul Sunchunhyang university hospital during 5 years from January, 1994 to December, 1998. Results: The incidence was 0.7%. The age distribution of mothers was 18 - 44 years and was highest in the 25 - 29 years range(46.4%). The parity was the most highest in the nulliparous group(51.8%). The most common gestational weeks was 20 - 28 weeks gestational period(46.4%), and most common presentation was cephalic(73.5%). The most common weights of the intrauterine fetal death was from 5,00gm to 1,000g(48.2%). The mode of the most common delivery was the induction of delivery(57.2%). The etiologic factors were: unknown(42.9%), preeclampsia(17.9%), chorioamnionitis(14.3%), congenital anomaly(12.5%), abruptio placenta(7.1%), cord complication(3.6%), placenta previa, death of one for twin. There were 2 cases of maternal complication(DIC, Uterine atony). Conclusion : Intrauterine fetal death should be diagnosised early and treated properly to reduce risk of the maternal complication.

인식 정당성의 의무론적 이해에 대한 비판과 대안

이해완(Lee, Hae-Wan) 서울대학교 철학사상연구소 2013 철학사상 Vol.50 No.-

이 글은 ‘인식 정당성’을 의무론적으로 이해하려는 이병덕과 임일환의 최근 논의를 비판적으로 검토한다. 잘 알려진 대로, 인식적 의무의 준수가 진리연관적이지 않다는 점과 믿음의 생성과 소멸을 의지적으로 통제할 수 없다는 점은 의무론적 이해에 대한 두 개의 주요한 반론이다. 이 글에서는 의무와 진리연관성을 직접 연결시키려는 듯 보이는 이병덕의 시도와 약한 인식적 의무를 주장하는 임일환의 입장이 모두 여전히 이 반론들을 극복하지 못하고 있음이 논증될 것이다. 보다 근본적인 차원에서 인식 정당성에 관한 소위 ‘포기할 수 없는 직관’으로 알려진 것의 근원들을 재검토해 본다면, 지식의 규범성이 반드시 의무 개념과 연계되어 이해되어야 할 필요는 없다는 점이 드러날 수 있을 것이다. 그로부터 출발하여 필자는 인식정당성에 대한 새로운 이해의 한 방향을 제안한다. 필자의 견해로는 믿음은 그 생성의 국면과 유지의 국면을 구별할 수 있는데, 진리연관성의 확보와 우연성의 배제를 위해 이 두 국면이 모두 평가될 필요가 있고, 이 두 국면에서 모두 좋은 믿음이 되는 것이 지식을 위해 필요하다. 믿음의 생성 국면은 기존의 정당화에 대한 신빙성 이론의 제안과 유사하게 평가될 수 있으며 그 결과 진리연관성을 확보할 수 있게 된다. 한편 유지 국면의 적절성을 외재론적으로 평가하는 것을 통해, 의무론적 이해의 옹호자들이 지식의 규범성과 관련하여 가지고 있는 통찰은 존중하되 그것이 ‘인식적 의무’와 같은 개념에 의존하지 않으면서도 설명될 수 있는 방법을 모색하고자 한다. 이 작업이 외재론적 틀 내에서 내재론의 착안점을 수용할 수 있는 이론의 가능성을 타진해 보는 시도가 될 수 있었으면 한다. This paper critically reviews two recently proposed, duty-based understandings on epistemic justification, one by Beong-Deok Lee and the other by Il-Hwan Rim. Having difficulty in securing truthconduciveness has been the major weakness of such deontological conceptions of justification. The fact that beliefs are formed involuntarily also casts a serious doubt on the concepts of epistemic duty. I argue that, unfortunately, those two new suggestions by Lee and by Rim still cannot live up to their billings by being susceptible to these already known attacks. Lee’s attempt to directly connect duty to truth-conduciveness fails, and Rim’s dependence on the concept of weak epistemic duty cannot circumvent the criticism of involuntarism, as he has intended. On the basis of this review, I propose a new way to understand epistemic justification. It is my contention that the concept of epistemic justification may be so technical that it is not guided by the intuition of justification (as there is none) but rather constructed artificially in accordance with what we think is needed for a true belief to become knowledge. What we need is truth conduciveness and, if a true belief is acquired by chance and/or maintained by chance, ways to get rid of relevant accidentality are involved. Thus I think that a belief should be evaluated as being good in the phase of both its acquisition and its maintenance in order to see if it qualifies as knowledge. A good belief in its acquisition phase may well be a belief produced by a reliable beliefforming process so that we can secure the truth-conduciveness. I suggest that a good belief in the maintenance phase can also be evaluated in an externalist’s perspective so that we can eliminate the involvement of a kind of accidentality, which in turn is a way to capture what deontologists want to hold as being epistemically important. The difference is that my proposal does not rely on the problematic conceptof epistemic duty.

조산의 예측 지표로서의 fetal fibronectin의 유용성

정집광,이해혁,이정재,이석민,이순곤,남계현,이임순,이권해 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Objective: The purpose of this study was to evaluate clinical efficacy of fetal fibronectin as a marker to predictor of preterm labor. Materials & Methods: The study group consisted of sixty-eight healthy pregnant women, at gestational age between 24 and 36 weeks, who visited our department with vaginal discharge from April, 1995 to December, 1997. For comparison, we divided all of the pregnant women into two groups by the result of ROM-Check^®, positive groups(N=21) and negative groups(N=47). When preterm labor appeared, 50mg of ritodrine hydrochloride(Yutopar^®) mixed I liter of 5% dextrose solution was administered slowly intravenously. Results: 1) The gestational age at delivery and the interval time from admission to delivery in the positive groups were significantly shorter than those of the negative groups(p<0.05). 2) The positive groups had significantly lower birth weight and Apgar scores than the negative groups(p<0.05). 3) Among the negative groups, in case of tocolytics administration, the interval time from admission to delivery significantly delayed more than that time in case of no tocolytics administration(p<0.05). Conclusions: The detection of the fetal fibronectin in vaginal discharge had a useful method as a predictor of preterm labor. Tocolytics was more effective in the negative groups than in the positive groups.

폐경기 여성에서 1년간 호르몬 대치 요법이 혈청 지질에 미치는 영향

이해혁,남계현,김승형,이임순,이권해,최승도 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Cardiovascular disease is one of the most common cause of death in postmenopausal women. After the onset of menopause, the risk of cardiovascular disease is increased. Several risk factors of cardiovascular disease are well known to us. Among the risk factors, the changes of lipid profiles are roles for cardiovascular disease. Estrogen appears to protect the development of cardiovascular disease, by several mechanism. Especially the protective effect is believed to be mediated by the changes of lipid profiles. Decreased high-density lipoprotein (HDL)-cholesterol and increased low density lipoprotein (LDL)-cholesterol are important factors for development of cardiovascular disease. The purpose of this study was to evaluate the effect of hormone replacement therapy on the lipid profiles to include total cholesterol (TC), high density lipoprotein(HDL)-cholesterol, low density lipoprotein(LDL)-cholesterol, and triglycerides. We measured lipid profiles in 31 postmenopausal women and gave each conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 5mg, day 1-12) for 12months. The levels of serum TC, LDL-cholesterol, and triglycerides were decreased significantly (p<0.05) and HDL-cholesterol was increased significantly (p<0.05) after 12months of hormone replacement therapy. These data suggest that hormone replacement therapy appears to protect agianst the development of cardiovascular disease by the changes of lipid profiles.

자궁경부 임신

이해혁,이권해 한국의학사 2000 診斷과治療 Vol.20 No.2

플라즈마 소결 PZT 세라믹스의 유전특성

이형직,송두규,권혁병,정해경,윤상옥,이형복,이홍림 국립7개대학공동논문집간행위원회 2003 공업기술연구 Vol.3 No.-

소결첨가제나 바인더를 넣지않고 만든 무첨가 PZT 분말 성형체를 플라즈마 소결-로 열처리 후의 미세조직의 변화, PbO의 거동 그리고 이에 따른 유전특성을 로소결한 경우와 비교하여 다음과 같은 결과를 얻었다. 플라즈마 소결-로 열처리로 만든 PZT 시편이 로 소결 시편과 비교하여 입성장이 크게 일어나지 않은 미세조직을 나타내었으며, 또한 균일한 Pb, Zr, Ti 성분분포를 보였다. 유전특성에 있어서는 1kHz에서 20%정도의 유전율의 향상을 얻을 수 있었으며 유전소실 또한 40%정도 낮출 수 있었다. 상기의 결과는 DC 플라즈마 소결법의 특징인 소결초기의 급속가열 효과와 PbO의 증발 억제 효과에 의한 것으로 고려된다. PZT powder compacts without additives and binder were processed by plasma sintering-furnace annealing. Microstructures, PbO behaviour and dielectric properties were investigated, and compared to the specimen obtained by furnace sintering. The specimen prepared by plasma sintering-furnace annealing showed more not only fine microstructures but also homogeneous pb, Zr, Ti composition distribution, and revealed 20% higher dielectric constant as well as 40% lower dielectric loss (measured at 1kHz). Above results might be considered to be caused by rapid heating effects, high temperature sintering effects and preventing effects of PbO evaporation characterized by dc plasma sintering.

In Vitro Fertilization and Embryo Cleavage in Canine Oocytes

Hae }ung Kim,Sang Ryeul Lee,Sin Hae Park,Sung Hyun Kim,Bong Soo Kim,Dong Hun Yoo,Sin Hae Park,Mi Jung Shin,Jae Wook Kim,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2006 Reproductive & developmental biology Vol.30 No.2

톨루엔을 포함한 유기용제의 직업적 폭로로 인한 신경내분비계 영향

이채언,이종태,정의화,손혜숙,문덕환,전진호,강정학,이창희,김휘동,김종한,정귀옥 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

Long term occupational exposure to solvent mixtures may cause adverse effects to the central nervous system with neurobehavioral symptoms. And some organic slovents have been suggested to cause impairment of tuberoinfundibular dopaminergic activity and neurochemical mechanisms controlling pituitary secretion. For the purpose of assessing neuroendocrine effects in occupational solvents exposure, hormonal study settings (shoes-manufacturing industry & fishing products industry) and compared with nonexposed controls(33 men, 85 women). Male workers exposed to solvent mixtures had significantly lower plasma level of follicle-stimulating hormone(FSH) than nonexposed male controls. While female workers exposed to solvent mixtures had significantly lower plasma levels of growth hormone(GH), and thyroid-stimulating hormone(TSH) than nonexposed female controls. The results of significant decrease in plasma concentrations of pituitary hormones(FSH, GH, and TSH) in workers exposed solvent mixtures indicate that occupational exposure to solvent mixtures may induce neuroendocrine effects through an effect on hypothalamic pituitary axis.

微量合金鋼의 機械的特質 向上에 미치는 析出物의 影響

李相允,李相雄,李熙太 동아대학교 공과대학 부설 한국자원개발연구소 1987 硏究報告 Vol.11 No.2

This study has been performed to investigate into various tensile properties of Fe-1.32% Si-0.34% C steel either quenched and tempered or isothermal-transformed after austenitizing at temperatures in the range of which both ferrite and austenite are present. The results obtained from the experiment are as follows; 1) The ductility is considerably improved by the addition of Si due to the fact that ferrite solution-strengthened and the formation of precipitates in ferrite is retarded. 2) Tensile test has shown that tensile properties of specimens isothermal-transformation treated are more improved as compared to the quenching and tempering treatment. 3) The saving of heat treatment energy and the reduction of manufacturing time can be achieved by simplifying heat treatment cycles to obtain better tensile properties than those generally obtainable from dual phase steels.

실측과 CFD을 통한 해인사 경내 및 판전에 대한 기류분포 특성의 조사

임종연(Lim Jong-Yeonn),송두삼(Song Doo-Sam),이상해(Lee Sang-Hae) 한국건축친환경설비학회 2007 한국건축친환경설비학회 논문집 Vol.1 No.3

Hae-In temple is located in Gaya Mountains, Hapcheon-gun, Korea and a thousand years old monastery. Tripitaka Koreana has been preserved during 750 years as good condition in Hae-In temple. The preservation technology is summarized as the passive design methods harmonized with the nature perfectly. Haein temple have dealt with a flow fields in the storage hall. In this study, an indoor and outdoor flow fields in the precincts of Haein temple were analysed with field measurement and numerical simulation. On the basis of the field measurement results, the restoration cases such as rearrangement of Tripitaka Koreana and relocation of the rear fence of Biro-Jean were analyzed with CFD.