Rifampin으로 예방적 항결핵요법 후 Etanercept를 사용 중인 류마티스 관절염 환자에서 발생한 결핵 1예

이혜원,이태화,김근태 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Tuberculosis infection is a rare but important side effect of anti-tumor necrosis factor agents that are widely used in the treatment of rheumatoid arthritis. A 63-year-old woman with rheumatoid arthritis who had been treated with etanercept visited the hospital because of polyarthralgia and right neck pain. Before use of etanercept, she was treated for latent tuberculosis. When the patient came to the hospital, she had no respiratory symptoms. But, we found abnormal findings in regularly follow-up chest x-ray. She was diagnosed as reactivation of latent tuberculosis by bronchoscopy. After stopping the etanercept, she has been treated with anti-tuberculosis agents, disease modifying anti-rheumatic drugs, and intra-articular steroid injection. We report here on this unusual case along with a review of the relevant literature

포괄적인 정보시스템 성과평가모형에 관한 연구

안봉근,주기중,권해익 한국경영과학회 2004 經營 科學 Vol.21 No.2

Measuring performance of corporate information system has become one of the core issues in that development of the information system requires substantial amount of investments and the system works as a crucial leverage to enhance competitive edge. Most of the previous researches for performance of the information system have narrow and limited focus on such as the effect of user satisfaction and productivity. This paper suggests a model to measures the comprehensive performance which is classified as user scope (user involvement and satisfaction), operational scope (task productivity, task innovation, customer satisfaction, management control) and efficiency scope (financial performance), and to represent the relationship among the scopes by the path analysis model. Followings are conclusions from statistical hypothesis test of the model: (ⅰ) user involvement through user satisfaction has positive effect on all the performances in the operational scope, (ⅱ) task innovation and customer satisfaction in the operational scope has statistically significant impact on financial performance but task productivity and management control do not. This conclusion indicates that task productivity and management control has the long term effect in nature, and evaluation of the information system has managerial implication when it is measured in comprehensive performance which includes internal operational performances as well as financial performance.

LAN에서 메세지 traffic 유형에 따른 성능 평가

임해진,신근하 三陟大學校 2001 論文集 Vol.34 No.1

Existing campus backbone networks will be replaced by Gigabit ethernet network which is able to handle various types of traffic and satisfying the needs of a large number of applications. For design of the Gigabit Ethernet, it is important to analysis exactly the characteristics of various type of traffic in current campus LAN networks. In this paper, We generalized campus communication networks which use a simulation techniques of QoS evaluation for remote traffic services and compare with the various backbone networks.

포플라 Callus의 배양환경에 따른 Anthocyanin 생합성

방혜진,이승우,최근원,정인식,설일환 경희대학교 생명자원과학연구원 1997 遺傳工學論文集 Vol.9 No.-

Studies were carried out to investigate the effects of various cultural and environmental conditions on callus growth and anthocyanin biosynthesis of the callus derived from the leaf discs of the Populus hybrid (Populus nigra × Populus maximowiczii cv. Yanghwangchul). Even though the largest amount of anthocyanin was obtained from the calli grown in the vessels illuminated with white fluorescent light, no significant differences in callus growth could be obtained among other vessels illuminated with different light qualities, i.e., red, yellow, blue, green and dark. Callus growth and anthocyanin biosynthesis were promoted by long-day conditions (16-hour photoperiod or longer). The calli grown in Schenk & Hildebrandt (SH) medium continuously (SH→SH) showed the best growth whereas the highest amount of anthocyanin biosynthesis was obtained in the calli grown in SH→SH or SH→White media.

Escherichia coli 패혈증 환자에 합병된 대칭적 하지 말단 괴사증 1예

남해성,유진홍,권순석,민준기,조현선,박민경,심병주,남유정,이지인,김진수,길욱현,조근종,신완식 대한감염학회 2005 감염과 화학요법 Vol.37 No.6

We have encountered a rare case of symmetrical peripheral gangrene complicating Escherichia coli sepsis in a 47-years-old male. He was successfully treated with antibiotics, anticoagulants, and vasodilator. To our knowledge, this is the first report on symmetrical peripheral gangrene complicating E. coli sepsis in Korea.

중학생의 사이버음란물 접촉과 정신건강

두근혜,홍해숙 경북대학교 간호과학연구소 2004 경북간호과학지 Vol.8 No.1

This study has been conducted to find out the connection between the current situation of middle school students` access to cyber pornography and their mental health by using the questionnaire with 71 questions targeted 707 male and female students from the middle school located in G city from the 3rd to the 16th of March in 2003. The collected data has been statistically processed by SPSS 10.0. The results of this study were as follows: 57.0% of the respondents has been exposed to pornography and it happened most frequently by accident while they were searching for information on the internet and the frequency of the exposure to pornography was the highest among the first grade students in the middle school. They watched pornography less than 30 minutes mostly at one time and the highest frequency of their access to it was "almost not", and 81.3% of the respondents watched in their houses. Most interviewers responded that they watched it because of their sexual curiosity and they normally watched it alone. The average mental health age of the respondents was 1.03. And seeing this result in detail by category, the imperative concept was the highest with the score of 1.67. The status of the mental health according to the access to cyber pornography showed a significant result(p<0.05) by exposure age, exposure time, exposure frequency, exposure motive, and who they watch with, but this result was not affected by how they became to watch. With the results above, I believe that the development of various prevention programs is necessary because cyber pornography affects mental health of middle school students.

지속적 런닝과 간헐적 런닝이 중년여성이 신체 구성과 혈청지질 및 지단백에 미치는 영향

서해근 대한스포츠의학회 2003 대한스포츠의학회지 Vol.21 No.1

The purpose of this study was to examine the changes of body composition, serum lipids and lipoproteins before & after continuous running(n=7) and intermittent running(n=7) training for 12 weeks on the middle-aged woman. The training based on all the subjects was practiced with the exercise intensity of 70% HRmax, and then, with 5 times a week, on running was also practiced without the rest during 30 minutes in the CRT group while the other was practiced with the repetitions of 3 times, during a continuous 10 minutes especially with the resting time of 10 minutes in the IRT group. The results are as follows: 1) Weight and BMI in the CRT and IRT groups were found to have the significant decrease of similar levels after training as the change of body composition, and then %fat and body fat were also found to have a very significant decrease, but to be more effective in the CRT group than in the IRT group. 2) TC and LDL-C in the CRT and IRT groups were found to have the significant decrease of similar levels. and then HDL-C was found to have the significant increase of similar levels after training as the change of serum lipid and lipoprotein. 3) Apo A-I in the CRT and IRT groups was found to have a significant increase after training as the change of apolipoprotein, and then Apo B was found to have a significant decrease but to be more effective in the CRT group than in the IRT group. As the above results, the continuous and intermittent running training in middle-aged woman, is found to have a positive effect in the improvement of the body composition and the metabolism of serum lipid and lipoprotein.

유아용 체력검사도구 개발을 위한 기초연구

최중근,황해익 부산대학교 영유아보육연구소 2002 영유아보육연구 Vol.8 No.-

The purpose of this study was to present materials on the development of physical assessment for young children when early childhood education facilities like kindergartens and nursery schools conduct physical exams. The following were the process and main findings of the study: First, the level of necessity for the development of physical assessment for young children was examined with kindergarten teachers the subjects. The subjects were 50 teachers from private and public kindergartens in city U. For the question "the necessity for the development of physical assessment", "very necessary" and "necessary" accounted for 83% of the respondents, which meant most teachers share the necessity and demand the development and popularization of the physical assessment. Second, the selection of exam items and their suitability were examined with experts the subjects. Among the 37 experts were 6 professors of early childhood education departments, 6 professors of physical education departments, 5 presenters in the academic journals of the associations related with young children' physical education, 10 trainers with over 3 years' experience in young children' physical education, and 10 kindergarten teachers with over 10 years' experience and the selection of exam items associated with the factors of young children' physical exam and their suitability were examined. The exam items selected by the experts were flexibility-trunk flexion sitting position test, speed-20-meter dash, balance-stork standing, body composition-body mass index(BMI), agility-zigzag run, muscular strength and muscular endurance-extended arm hanging, and power-standing broad and long jump. As for the suitability of the selected items, more than 70% of the experts replied "very suitable" and "suitable." Third, the trial plan of "physical assessment for children" chosen by the experts was applied on 78 infants attending S kindergarten in city U : 15 full 3-year-olds, 33 full 4-year-olds, and 30 full 5-year-olds. The "physical assessment for young children" turned out to be suitable in general. Fourth, "the application outline of convenient physical assessment for young children" and "the record card of convenient physical assessment for young children" were presented for the convenience of the field use by analyzing the results from the field test. As the teachers in the field required, convenient physical assessment for young children should be developed and popularized and the development of young children' physical strength needs to be promoted by devising evaluation criteria of the national level.

하악골에서 발생한 골아 세포종을 닮은 골육종의 치험 1례

이성근,정인교,박혜련 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.3

Typical osteoblastoma is generally considered to be a rare benign primary bone tumor that is seen primarily in children and young adults and curable by complete excision. However, the recurrence, aggressive behavior, or malignant transformation of this lesion was reported in some cases. It is reported that the malignant or aggressive osteoblatoma is really osteoblastoma-like osteosarcoma. Therefore, although this lesion is diagnosed as benign histologically. the operator must observe the postoperative course carefully. This article is to report a case of osteoblastoma-like osteosarcoma occurred in the mandible of 22 years old male patient with literature review.

확률순위 방법에 의한 다특성치 최적화 설계

안봉근,권해익 啓明專門大學 産業開發硏究所 2000 啓明硏究論叢 Vol.18 No.1

품질개선을 위한 파라미터 설계(parameter design)는 제품설계 단계에 있어서 제품의 특성치에 영향을 미치는 설계변수를 발견하고, 품질특성치가 목표치에 접근하도록 설계변수의 값을 최적화시키는 파라미터 값을 결정하는 것이다. 본 연구는 품질특성치가 여러 개인 다특성치에 대한 파라미터 설계시 품질특성치에 영향을 미치는 설계변수의 최적조건을 결정하는 기존의 방법의 문제점을 파악하여 이러한 문제점을 해결할 수 있는 대안의 하나로서 확률순위 방법을 적용하였다. 특성치간 상충현상이 발생하는 A사의 시뮬레이션 자료를 사용하여, 실증 분석하였으며, 논문에서 제안한 모형을 활용하여 최적설계변수의 수준을 결정하였다. The parameter design for quality improvement is the design for identifying the design variables with impact on the product characteristics in the product design process and for determining the parameter values optimizing the values of design variables for the quality characteristics which are approached the goal. The study grasps the problems of the previous methods determining the optimal condition of the design variables with impact on the product characteristics in the case of parameter design of the individual multi-variate characteristics. As an alternative to solution of such problems, the study suggests stochastic ordering method. The empirical analysis in the study uses simulation data of A company where there exists the conflict among the characteristics and determines the level of optimal design variables by applying suggested model in this study.