La question du genre et des TNIC au prisme du dialogue de la sociologie et de la sémiotique

Hélène Bourdeloie,Véronique Julliard 고려대학교 응용문화연구소 2013 에피스테메 Vol.0 No.9

This contribution studies the seniors’ practices in relation with Digital Information and Communication Technologies (DICT) and gendered identities that are built through these practices. We make the hypothesis that Sex is a determining factor and that Gender structures practices as well as representations. The authors congujate sociological and semiotic approaches upon two fields: firstly, two groups of persons over 60 years, which one has followed a training to DICT, secondly, the Social Networking Service (SNS) Quintonic. The study reveals that beyond gender divisions, the seniors’ practices make sense in the system of Gender-which distributes centers of interests between men and women-, participating in the construction of gendered identities. Furthermore, the SNS, because of their expressive dimensions, allow gender norms’ interpretations. These interpretations question gendered identities. Cette contribution étudie les pratiques des seniors liées aux technologies numériques de l’information et de la communication (TNIC) et les identités de genre qui s’élaborent via ces pratiques, l’hypothèse étant que le sexe est là un facteur déterminant et que le genre structure tant les pratiques que les représentations. Les auteures font ici dialoguer des approches sociologique et sémiotique sur deux terrains : deux groupes de seniors âgés de 60 ans, dont l’un a suivi une formation aux TNIC, et le réseau socionumérique (RSN) Quintonic. Il ressort de l’étude qu’au-delà de leur sexuation, les pratiques des seniors prennent sens dans le système du genre-qui distribue les centres d’intérêt entre les sexes-, et participent à la construction des identités de genre. Par ailleurs, certaines TNIC, telles qu’un RSN, de par leurs dimensions éditoriale et expressive, donnent lieu à des interprétations des normes de genre, interprétations susceptibles de redessiner les identités de genre traditionelles.

Pollen/Fruit Syndrome: Clinical Relevance of the Cypress Pollen Allergenic Gibberellin-Regulated Protein

Hélène Sénéchal,Sanaz Keykhosravi,Rémy Couderc,Marie-Ange Selva,Youcef Shahali,Tomoyasu Aizawa,Jean-Marc Busnel,Rihane Arif,Inna Mercier,Nhan Pham-Thi,Denis-André Charpin,Pascal Poncet 대한천식알레르기학회 2019 Allergy, Asthma & Immunology Research Vol.11 No.1

A pollen/food-associated syndrome (PFAS) has been described between peach and cypress pollen. Cross-reactive allergens were characterized which belong to the Gibberellin-regulated protein (GRP) family, BP14 in cypress pollen and Pru p 7 in peach. GRP are small cationic protein with anti-microbial properties. A patient suffering from a peach/cypress syndrome was explored clinically and biologically using 2 types of immunoglobulin E (IgE) multiarray microchip, immunoblots and a basophil activation test to assess the clinical relevance of various extracts and purified allergens from fruits or cypress pollen. In addition to PR10 sensitization, the patient showed specific IgE to Pru p 7, BP14 and allergen from pomegranate. These last 3 allergens and allergenic sources are able to induce ex vivo basophil activation characterized by the monitoring of the expression of CD63 and CD203c, both cell surface markers correlated with a basophil mediator release. Up to 100% of cells expressed CD203c at 50 ng/mL of BP14 protein. In contrast, snakin-1, a GRP from potato sharing 82% sequence identity with Pru p 7 did not activate patient's basophils. These results strongly suggest that, like Pru p 7, BP14 is a clinically relevant allergenic GRP from pollen. Allergen members of this newly described protein family are good candidates for PFAS where no cross-reactive allergens have been characterized.

Role of Rapid Drink Challenge During Esophageal High-resolution Manometry in Predicting Outcome of Peroral Endoscopic Myotomy in Patients With Achalasia

( Hélène Foisy ),( Mathieu Pioche ),( Edouard Chabrun ),( Thierry Ponchon ),( Frank Zerbib ),( Jérôme Rivory ),( François Mion ),( Sabine Roman ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2020 Journal of Neurogastroenterology and Motility (JNM Vol.26 No.2

Background/Aims Peroral endoscopy myotomy (POEM) is effective to treat achalasia. We aim to determine POEM effect on esophageal function and search for predictive factors of response to POEM and co-occurrence of gastroesophageal reflux disease (GERD). Methods A total of 64 untreated achalasia patients who underwent high-resolution manometry (HRM) before and 3 months after POEM were retrospectively included. Response to treatment was defined as an Eckardt score < 3. Reflux symptoms and patient’s satisfaction were evaluated. Data were compared using paired t test, Chi-square test or log rank test. Results The 2-year success rate in response to POEM was 90%. All responders reported being satisfied while only 33% of non-responders did (P < 0.001) and 64% of patients with reflux symptoms were satisfied versus 96% of those without (P = 0.009). On HRM, the integrated relaxation pressure and the contractile pattern changed significantly after POEM but were not predictive of response. Between pre and post POEM HRM, a decrease in maximal esophageal pressurization during rapid drink challenge (RDC) was associated with a better response rate than an increase of pressurization (91% vs 50%, P = 0.004). As evidenced by pH monitoring performed after POEM, GERD was pathological or borderline in 50% of patients (18/36) while only 19% (11/59) reported clinically significant reflux symptoms. On post POEM HRM, maximal esophageal pressurization during RDC was lower in patients with pathological or borderline GERD compared to those without (P = 0.054). Conclusions Esophageal HRM parameters changed significantly after POEM. Maximal esophageal pressurization during RDC may be useful to predict outcome. (J Neurogastroenterol Motil 2020;26:204-214)

Systematic Early Urinary Catheter Removal Integrated in the Full Enhanced Recovery After Surgery (ERAS) Protocol After Laparoscopic Mid to Lower Rectal Cancer Excision: A Feasibility Study

Hélène Meillat,Cloé Magallon,Clément Brun,Cécile de Chaisemartin,Laurence Moureau-Zabotto,Julien Bonnet,Marion Faucher,Bernard Lelong 대한대장항문학회 2021 Annals of Coloproctolgy Vol.37 No.4

Purpose: Enhanced Recovery After Surgery (ERAS) programs advocate early urinary catheter removal after rectal cancer surgery; however, the optimal duration remains unclear. This study assessed the feasibility of the early urinary catheter removal protocol after rectal cancer surgery within an ERAS pathway and identified predictive factors for failure of this strategy.Methods: Between March 2017 and October 2018, all unselected and consecutive patients who underwent rectal cancer resection and benefited from our ERAS program were included. Urinary complications (infection and retention) were prospectively recorded. Success was defined as catheter removal on postoperative day (POD) 3 without urinary complications.Results: Of 135 patients (male, 63.7%; neoadjuvant chemoradiation, 57.0%; urology history, 17.8%), 120 had early urinary catheter removal with no complications (success rate, 88.9%), 8 did not have urinary catheter removal on POD 3 due to clinical judgment or prescription error, 5 experienced a urinary tract infection, and 2 had acute urinary retention. Obesity (odds ratio [OR], 0.16; P = 0.003), American Society of Anesthesiologists physical status classification > II (OR, 0.28; P = 0.048), antiaggregant platelet medication (OR, 0.12; P < 0.001), absence of anastomosis (OR, 0.1; P = 0.003), and prolonged operative time (OR, 0.21; P = 0.020) were predictive factors for failure. Conversely, optimal compliance with the ERAS program (OR, 7.68; P < 0.001), postoperative nonsteroidal anti-inflammatory drug use (OR, 21.71; P < 0.001), and balanced intravenous fluid therapy (OR, 7.87; P = 0.001) were associated with increased strategy success.Conclusion: Withdrawal of the urinary catheter on POD 3 was successfully achieved after laparoscopic rectal resection and can be safely implemented in the ERAS program.

Evaluation of sFlt-1/PlGF Ratio for Predicting and Improving Clinical Management of Pre-eclampsia: Experience in a Specialized Perinatal Care Center

Hélène Caillon,Cécile Tardif,Erwan Dumontet,Norbert Winer,Damien Masson 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.2

Background: Management of pregnant women at high risk of pre-eclampsia (PE) requires frequent monitoring, with referral to specialized perinatal care centers. Reliable tests are necessary to improve prediction of PE and related complications and to assess disease severity and progression. An imbalance in two biomarkers, soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF), is involved in PE pathogenesis. The sFlt-1 to PlGF ratio is increased in pregnant women before the onset of PE. An elevated ratio is highly predictive of PE, whereas the diagnosis of PE can be ruled out within one week for low ratios. The main objective of this study was to assess whether a low sFlt-1/PlGF ratio, below a cutoff of 38, can predict the absence of PE within one week.

A combinatorial constraint satisfaction problem dichotomy classification conjecture

Neš,etř,il, Jaroslav,Siggers, Mark H.,Zá,dori, Lá,szló Elsevier 2010 European journal of combinatorics : Journal europ& Vol.31 No.1

<P><B>Abstract</B></P><P>We further generalise a construction–the <I>fibre construction</I>–that was developed in an earlier paper of the first two authors. The extension in this paper gives a polynomial-time reduction of CSP(H) for any relational system H to CSP(P) for any relational system P that meets a certain technical partition condition, that of being <SUB>K3</SUB>-<I>partitionable</I>.</P><P>Moreover, we define an equivalent condition on P, that of being <I>block projective</I>, and using this show that our construction proves NP-completeness for exactly those CSPs that are conjectured to be NP-complete by the CSP dichotomy classification conjecture made by Bulatov, Jeavons and Krohkin, and by Larose and Zádori. We thus provide two new combinatorial versions of the CSP dichotomy classification conjecture.</P><P>As with our previous version of the fibre construction, we are able to address restricted versions of the dichotomy conjecture. In particular, we reduce the Feder–Hell–Huang conjecture to the CSP dichotomy classification conjecture, and we prove the Kostochka–Nešetřil–Smolíková conjecture. Although these results were proved independently by Jonsson et al. and Kun respectively, we give different, shorter, proofs.</P>

Interpreting luxury and fashion across Anthropocene pandemics

Cristini Hélène,Woodside Arch G. 한국마케팅과학회 2023 Journal of Global Fashion Marketing Vol.14 No.1

Pandemics afflict human beings across millennia. Pandemics arise in different historical periods reflecting particular cultural ethos. Pandemics are time markers that take place in different paradigms. People’s movements and economic processes encompassing the luxury industry trigger pandemics. This study presents several paradigms as unique processes of pandemics associating with respective luxury behaviors. This study’s objectives include questioning economic models and examines how Anthropocene historical eras are transformable for better or worse.

Impact of functional inorganic nanotubes f‑INTs‑WS2 on hemolysis, platelet function and coagulation

Julie Laloy,Hélène Haguet,Lutfiye Alpan,Daniel Raichman,Jean‑Michel Dogné,Jean‑Paul Lellouche 나노기술연구협의회 2018 Nano Convergence Vol.5 No.31

Inorganic transition metal dichalcogenide nanostructures are interesting for several biomedical applications such as coating for medical devices (e.g. endodontic files, catheter stents) and reinforcement of scaffolds for tissue engineering. However, their impact on human blood is unknown. A unique nanomaterial surface-engineering chemical methodology was used to fabricate functional polyacidic polyCOOH inorganic nanotubes of tungsten disulfide towards covalent binding of any desired molecule/organic species via chemical activation/reactivity of this former polyCOOH shell. The impact of these nanotubes on hemolysis, platelet aggregation and blood coagulation has been assessed using spectrophotometric measurement, light transmission aggregometry and thrombin generation assays. The functionalized nanotubes do not induce hemolysis but decrease platelet aggregation and induce coagulation through intrinsic pathway activation. The functional nanotubes were found to be more thrombogenic than the non-functional ones, suggesting lower hemocompatibility and increased thrombotic risk with functionalized tungsten disulfide nanotubes. These functionalized nanotubes should be used with caution in blood-contacting devices.

Machine tool architecture selection at the preliminary design stage: application to hard material machining

Montassar Lajili,Hélène Chanal,Belhassen Chedli Bouzgarrou 한국CDE학회 2020 Journal of computational design and engineering Vol.7 No.5

The preliminary design stage ensures to evaluate machine tool performances according to the simulation of reduced models. Performance criteria are defined regarding the attempted machining process requirements. In our case, we study the problem of machine tool design for hard metal cutting, where a high level of stiffness is required. In this context, this paper’s aim is to introduce a new methodology of machine tool architectures modeling, optimization, and selection with regards to their stiffness and dynamic performances at the preliminary design stage. However, this type of study requires a quantitative evaluation of performance indicators. Studied machine tool structures are modelled with simplified shape parts. The dimensions of these parts are defined as design variables. Afterward, for each considered architecture, parametric design optimization is performed to minimize its mass under the constraint of a minimal attempted stiffness all over the workspace. This approach allowed restricting the total number of machine tool architectures to be detailed further and analyzed more accurately. In a first time, the paper includes an illustration of the developed methodology through an example of machine tool architecture evaluation and optimization. In a second time, the method is used to compare different kinds of machine tool architectures regarding their ability to be light for an attempted stiffness.

Proposal for a New Score: Hemorrhoidal Bleeding Score

Nadia Fathallah,Hélène Beaussier,Gilles Chatellier,Jean Meyer,Marc Sapoval,Nadia Moussa,Vincent de Parades 대한대장항문학회 2021 Annals of Coloproctolgy Vol.37 No.5

Purpose: We conducted a prospective study to evaluate a new hemorrhoidal bleeding score (HBS).Methods: All consecutive patients who had consulted between May 1, 2016 and June 30, 2017 for bleeding hemorrhoidal disease were prospectively assessed at a proctological department. The study was conducted in 2 stages. The first stage assessed the validity of the score on a prospective patient cohort. A second stage assessed the interobserver reproducibility of the score on another prospective cohort.Results: One hundred consecutive patients were studied (57 males; mean age, 49.70 years). A positive association between HBS and surgery indication was found (P<0.001). A cut-off value of the score of 5 (≤5 vs. >5) separated patients from surgical to medical-instrumental treatment with a sensitivity and specificity of 75.00% and 81.25%, respectively. In the multivariate analysis, only HBS was significantly associated with the operative decision (odds ratio, 12.22). Prolapse was no longer significantly associated with the surgical indication. After a mean follow-up after treatment of 7 months, HBS improved statistically significantly (P<0.0001). For the reproducibility of the score, an additional 30 consecutive patients (13 males; mean age, 53.14 years) were enrolled with an excellent agreement between 2 proctologists (kappa=0.983).Conclusion: HBS is sensitive, specific, and reproducible. It can assess the severity of hemorrhoidal bleeding. It can discriminate between the most severe surgery-indicated patients and does so in a more efficient way than the Goligher prolapse score. It also allows quantifying the extent of change in hemorrhoidal bleeding after treatment.