http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
승삼선,유신오,노경호 三陟大學校 産業科學技術硏究所 2002 産業科學技術硏究論文集 Vol.7 No.1
In this study, open type wind tunnel has been restructured instead air blower. its designed and fabricated part are diffuser. settling chamber with screen, contraction or nozzle, and test section. Also inverter enable to control variable speeds. And basic experiments have been performed to check the flow characteristics for restructured open type wind tunnel. In these procedures, we have got some conclusion. the control of contraction is valid for X = 0.40 considering Morel's and Fang's suggestion. it is confirmed that the two pressure coefficients for avoiding separation is satisfied with Fang's result. Distribution of uniform velocity in test section are stabilized above 95~99%.
진행성 위암에 대한 1차 요법으로 Docetaxel과 Cisplatin 복합화학요법의 효과와 안정성에 대한 연구
김경중 ( Gyung Jung Kim ),이세동 ( Sehe Dong Lee ),박종원 ( Jong Won Park ),신철호 ( Cheol Ho Sin ),황승재 ( Seung Jae Hwang ),남승현 ( Seung Hyun Nam ),김봉석 ( Bong Seog Kim ) 대한내과학회 2007 대한내과학회지 Vol.72 No.6
본 연구에서는 수술 후 재발한 진행성 또는 절제 불가능한 전이성 위암을 가진 42명의 환자를 대상으로 1차 항암요법으로 docetaxel과 cisplatin을 투여하여 높은 반응률과 감내할만한 부작용을 확인할 수 있었다. 향후 많은 환자를 대상으로 한 전향적 연구와 표적치료제를 포함한 병용치료에 대한 연구가 필요할 것으로 판단된다. Background: To evaluate the activity and safety of docetaxel and cisplatin for advanced gastric cancer as a first-line chemotherapy treatment. Methods: Between December 2001 and February 2006, forty-two patients with recurrent or metastatic gastric cancer were enrolled. Docetaxel (75 mg/m2) was administered as a 1-hour intravenous infusion on day 1 and cisplatin (60 mg/m2) was also administered as a 30-minute intravenous infusion on day 1 every three weeks until disease progression or severe toxicity was detected. The response was assessed every 2 cycles. The toxicities were evaluated for every course of chemotherapy according to NCI toxicity criteria. Results: The median age of the patients was 66 (range, 33~77) years. Among the forty-two patients, 38 were male. Twenty-seven patients had an Eastern Cooperative Oncology Group performance score of 0 or 1 and fifteen patients had a score of 2. All patients had adenocarcinoma. Thirty-three of the forty-two patients were assessable for response. Partial responses were observed in 14 patients. The overall response rate was 42.4% (95% C.I., 25.259.6%) and the median response duration was 5.7 (range, 1.4~17.2) months. The median overall survival of all patients was 8.1 (range, 1.2~47.0) months. During a total of 170 cycles, granulocytopenia worse than National Cancer Institute toxicity grade 3 occurred in 7.6% of the patients, thrombocytopenia in 0.6% and anemia in 3.5%, respectively. No deaths resulting from toxicity were observed. Non-hematologic toxicities were minor and were easily controlled. Conclusion: Combination chemotherapy with docetaxel and cisplatin has a tolerable efficacy with acceptable toxicities in patients with advanced gastric cancer as a first-line treatment. (Korean J Med 72:593-599, 2007)