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Gweon, Hyun-Soo,Sung, Hee-Ja,Lee, Dae-Hee The Korean Nutrition Society 2010 Nutrition Research and Practice Vol. No.
The precise effects of protein intake on fractional synthesis rate (FSR) of muscle protein are still under debate. The sample size of these studies was small and the conclusions in young and elderly subjects were inconsistent. To assess the effect of dietary protein intake on the FSR level, we conducted a meta-analysis of controlled protein intake trials. Random-effects models were used to calculate the weighted mean differences (WMDs). Ten studies were included and effects of short-term protein intake were evaluated. In an overall pooled estimate, protein intake significantly increased the FSR (20 trials, 368 participants; WMD: 0.025%/h; 95%CI: 0.019-0.031; P < 0.0001). Meta-regression analysis suggested that the protein dose was positively related to the effect size (regression coefficient = 0.108%/h; 95%CI: 0.035, 0.182; P = 0.009). A subgroup analysis indicated that protein intake significantly increased FSR when the protein dose was ${\leq}$ 0.80 g/kg BW (16 trials, 308 participants; WMD: 0.027%/h; 95%CI: 0.019-0.031; P < 0.0001), but did not affect FSR when the protein dose was > 0.80 g/kg BW (4 trials, 60 participants; WMD: 0.016%/h; 95%CI: 0.004-0.029; P = 0.98). In conclusion, this study is the first integrated results showing that a short-term protein intake is effective at improving the FSR of muscle protein in the healthy elderly as well as young subjects. This beneficial effect seems to be dose-dependent when the dose levels of protein range from 0.08 to 0.80 g/kg BW.
Escherichia coli deactivation study controlling the atmospheric pressure plasma discharge conditions
Gweon, B.,Kim, D.B.,Moon, S.Y.,Choe, W. Elsevier 2009 CURRENT APPLIED PHYSICS Vol.9 No.3
Bio-applications of plasma have been widely studied in recent years. However, considering the high interests, the inactivation mechanisms of micro-organisms by plasma have not been clearly explained. The goal of this study was to find the sterilization mechanisms and define the major sterilization factors with the atmospheric pressure radio-frequency helium glow discharge. For the sterilization target the Escherichia coli was used. To begin with the sterilization study, the plasma characteristics were investigated by means of electrical and optical diagnostics. Especially, the gas temperature was controlled under 50<SUP>o</SUP>C by keeping the input power less than 70W to eliminate the thermal effects. Contribution of the UV irradiation from the plasma was studied and it turned out to be negligible. On the other hand, it was found that the sterilization was more effective up to 40% with only 0.15% oxygen addition to the helium supply gas. It indicates that the inactivation process was dominantly controlled by oxygen radicals, rather than heat or UV photons.
Gweon, Tae-Geun,Kim, Sang Woo,Noh, Yong-Sun,Hwang, Seawon,Kim, Na-Young,Lee, Yoonbum,Lee, Soon-Wook,Lee, Sung Won,Lee, Jong Yul,Lim, Chul-Hyun,Hun Kim, Hyung,Kim, Jin Su,Kyung Cho, Yu,Myung Park, Jae Wolters Kluwer Health 2015 Medicine Vol.94 No.13
<P><B>Abstract</B></P><P>For afternoon colonoscopy, same-day administration of sodium picosulfate, magnesium oxide, and citric acid (PM/Ca) is recommended. However, few studies have evaluated the bowel-cleansing efficacy and safety of this regimen. The aim of this study was to compare the bowel-cleansing efficacy, side effects, and patient's tolerability of a same-day split administration of PM/Ca with polyethylene glycol (PEG) for afternoon colonoscopy.</P><P>Patients were randomly assigned to a PM/Ca group or a PEG group. The PM/Ca group consumed 1 sachet of PM/Ca at 06:00 and 1 sachet of PM/Ca 4 hours before the colonoscopy. They also took 2 tablets of bisacodyl before sleep on the night before. The PEG group consumed 2 L of PEG at 06:00 and 2 L of PEG 4 hours before the colonoscopy. All subjects were instructed to finish the bowel cleanser or fluid at least 2 hours before colonoscopy. All colonoscopic examinations were performed in the afternoon on the same day. The bowel-cleansing efficacy was scored using 2 scales: the Ottawa Bowel Preparation Scale (OBPS) and the Aronchick scale. Ease of using the bowel cleanser was rated from 1 (very easy) to 5 (very difficult).</P><P>Two hundred nine patients underwent colonoscopy. The bowel-cleansing scores by OBPS did not differ between groups (5.0 vs 4.9, <I>P</I> = 0.63). Ease of using the bowel cleanser was superior in the PM/Ca group (<I>P</I> < 0.01).</P><P>The cleansing efficacy of PM/Ca administered on the day of colonoscopy is comparable to that of PEG. Patients prefer PM/Ca.</P>
Prolongation of Neuromuscular Block of Succinylcholine Chloride by Ketamine in Rabbits
Gweon, Kyeong Deog,Chung, Woon Hyok CATHOLIC MEDICAL CENTER 1980 Bulletin of the Clinical Research Institute Vol.8 No.1
The effect of ketamine on the muscle relaxation produced by succinylcholine chloride was studied. The cause of prolongation of neuromuscular block of succinylcholine chloride by ketamine was discussed. The clinical dose of S.C.C. should be carefully adjusted, if ketamine would be administered.
Gweon, Hye Mi,Cho, Nariya,Seo, Mirinae,Chu, A Jung,Moon, Woo Kyung Springer International 2014 EUROPEAN RADIOLOGY Vol.24 No.8
<P>To investigate whether kinetic features via magnetic resonance (MR)-computer-aided evaluation (CAE) can improve the positive predictive value (PPV) of morphological descriptors for suspicious lesions at screening breast MRI.</P>
Gweon,Seong-Cheol 啓明大學 産業經營硏究所 1976 經營經濟 Vol.7 No.1
A few illustrations of multinational corporation could be found seventy-five or one hundred years ago, but the flowering of their particular form of enterprise did not occur until, after World War II, the increasing trend of foreign trade was revealed (see Table I-1).
Gweon, Tae-Geun,Kim, Jinsu,Lim, Chul-Hyun,Park, Jae Myung,Lee, Dong-Gun,Lee, In Seok,Cho, Young-Seok,Kim, Sang Woo,Choi, Myung-Gyu Hindawi Publishing Corporation 2016 Gastroenterology Research and Practice Vol.2016 No.-
<P><I>Background and Aims</I>. Fecal microbiota transplantation (FMT) is a highly effective treatment option for refractory<I> Clostridium difficile</I> infection (CDI). FMT may be challenging in patients with a low performance status, because of their poor medical condition. The aims of this study were to describe our experience treating patients in poor medical condition with refractory or severe complicated CDI using FMT via the upper GI tract route.<I> Methods</I>. This study was a retrospective review of seven elderly patients with refractory or severe complicated CDI and a poor medical condition who were treated with FMT through the upper GI tract route from May 2012 through August 2013. The outcomes studied included the cure rate of CDI and adverse events.<I> Results</I>. Of these seven patients who received FMT via the upper GI tract route, all patients were cured. During the 11-month follow-up period, CDI recurrence was observed in two patients; rescue FMT was performed in these patients, which led to a full cure. Vomiting was observed in two patients.<I> Conclusions</I>. FMT via the upper gastrointestinal tract route may be effective for the treatment of refractory or severe complicated CDI in patients with a low performance status. Physicians should be aware of adverse events, especially vomiting.</P>