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Aortopulmonary Fistula Presenting without an Endoleak after Thoracic Endovascular Aortic Repair
Giacomo Sica,Gaetano Rea,Giorgio Bocchini,Romilda Lombardi,Massimo Muto,Tullio Valente 대한흉부외과학회 2017 Journal of Chest Surgery (J Chest Surg) Vol.50 No.4
Herein, we report the case of a 60-year-old man, a smoker with a history of arterial hypertension and diabetes mellitus. After computed tomography (CT) for an episode of hemoptysis, the patient underwent elective thoracic endovascular aortic repair (TEVAR) because of a degenerative aneurysm of the descending thoracic aorta. The area of perianeurysmal pulmonary atelectasis reported on the CT scan was not considered. Three months later, he developed an aortopulmonary fistula without endoleaks. Although TEVAR is a relatively safe procedure, no detail should be overlooked in the preoperative evaluation in order to avoid life-threatening complications. Further, the effectiveness and modality of prolonged antibiotic prophylaxis and/or preoperative respiratory physiotherapy should be assessed in such cases.
How Did Maritime Piracy Affect Trade in Southeast Asia?
Giacomo Morabito,Bruno S. Sergi 동아시아연구원 2018 Journal of East Asian Studies Vol.18 No.2
Over the past 30 years, Southeast Asia has experienced rapid growth in intra-regional economic activity, but despite the remarkable diminution in the frequency and intensity of military conflict and crises, it has not been free of interstate disputes, such as maritime disputes. However, the struggle against maritime crime activities such as maritime piracy is a priority for all countries of the region, as well as one of the unavoidable prerequisites for the achievement of the regional economic security. This research note focuses on the impact of maritime piracy on the Southeast Asian countries’ trade. Bilateral trade flows among the Southeast Asian countries over the 1994 to 2013 period are used to estimate an augmented gravity model that includes various measures of maritime crime activities. The purpose is to find the evidence to indicate how maritime piracy has affected the volume of intra-regional trade.
Giacomo Corrado,Giuseppe Cutillo,Emanuela Mancini,Ermelinda Baiocco,Lodovico Patrizi,Maria Saltari,Anna di Luca Sidozzi,Isabella Sperduti,Giulia Pomati,Enrico Vizza 대한부인종양학회 2016 Journal of Gynecologic Oncology Vol.27 No.4
Objective: To compare surgical outcomes and cost of robotic single-site hysterectomy (RSSH) versus robotic multiport hysterectomy (RMPH) in early stage endometrial cancer. Methods: This is a retrospective case-control study, comparing perioperative outcomes and costs of RSSH and RMPH in early stage endometrial cancer patients. RSSH were matched 1:2 according to age, body mass index, comorbidity, the International Federation of Gynecology and Obstetric (FIGO) stage, type of radical surgery, histologic type, and grading. Mean hospital cost per discharge was calculated summarizing the cost of daily hospital room charges, operating room, cost of supplies and length of hospital stay. Results: A total of 23 women who underwent RSSH were matched with 46 historic controls treated by RMPH in the same institute, with the same surgical team. No significant differences were found in terms of age, histologic type, stage, and grading. Operative time was similar: 102.5 minutes in RMPH and 110 in RSSH (p=0.889). Blood loss was lower in RSSH than in RMPH (respectively, 50 mL vs. 100 mL, p=0.001). Hospital stay was 3 days in RMPH and 2 days in RSSH (p=0.001). No intraoperative complications occurred in both groups. Early postoperative complications were 2.2% in RMPH and 4.3% in RSSH. Overall cost was higher in RMPH than in RSSH (respectively, $7,772.15 vs. $5,181.06). Conclusion: Our retrospective study suggests the safety and feasibility of RSSH for staging early endometrial cancer without major differences from the RMPH in terms of surgical outcomes, but with lower hospital costs. Certainly, further studies are eagerly warranted to confirm our findings.
Giacomo Emanuele Maria Rizzo,Giuseppina Ferro,Giovanna Rizzo,Giovanni Di Carlo,Alessandro Cantone,Gaetano Giuseppe Di Vita,Carmelo Sciumè 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.2
Iatrogenic perforations are severe complications of gastrointestinal endoscopy; therefore, their management should be adequatelyplanned. A 77-year-old man with a history of diverticulosis underwent a colonoscopy for anemia. During the procedure, aniatrogenic perforation occurred suddenly in the sigmoid colon, near a severe angle among the numerous diverticula. Through-thescopeclips were immediately applied to treat it and close mucosal edges. Laboratory tests showed increased levels of inflammationand infection, and although there were no complaints of abdominal pain, the patient had an extremely distended abdomen. Amultidisciplinary board began management based on a conservative approach. Pneumoperitoneum was treated with computedtomography-assisted drainage. After 72 hours, his intestinal canalization and laboratory tests were normal. Though this adverseevent is rare, a multidisciplinary board should be promptly gathered upon occurrence, even if the patient appears clinically stable, toconsider a conservative approach and avoid surgical treatment.
Giacomo Gistri,Matteo Corciolani,Stefano Pace 한국마케팅과학회 2018 Journal of Global Fashion Marketing Vol.9 No.3
An organizational crisis is an event perceived by managers and stakeholders as highly salient, unexpected, and potentially disruptive; it can also threaten an organization’s goals and have profound implications for its relationships with stakeholders. In this article, we consider an actual crisis that recently struck an important brand in the fashion sector – Moncler. The crisis endured by Moncler was complex, involving several aspects of its activity. Notably, our study was conducted at the beginning of November 2014, in the 2 weeks after the crisis event. In particular, to collect data on consumers’ reactions to Moncler crisis, we created a questionnaire and ran a web survey through Survey Monkey. Then, through a moderated mediation model, we show that the impact of brand identification on the attitude toward the company and purchase intention is significantly mediated by anger for high levels of personal crisis relevance (PCR) and by sympathy for average and low PCR levels. These results are in accordance with some research concerning the role of emotions, which can perform different functions; the function of emotions such as anger and sympathy is to support the individual’s commitment and relate to moral decisions and judgements.
Giacomo Garibotto,Pasquale Esposito,Daniela Picciotto,Daniela Verzola 대한신장학회 2019 Kidney Research and Clinical Practice Vol.38 No.4
Both myostatin (MSTN) and activin A, two peptide members of the transforming growth factor (TGF)-β super family, have been suggested to play major roles in complications of chronic kidney disease (CKD), including vascular and bone disease. Both MSTN and activin A share many similarities in terms of structure, signaling pathway, and functions with TGF-β, and have been initially studied as players in muscle cachexia in CKD and several other chronic diseases [1]. However, the last few years have witnessed a paradigm shift with respect to our understanding of the effects of MSTN/activin signaling in organs distant from muscle. There is ever-increasing evidence that the MSTN/activin pathway impacts the heart, arterial vessels, insulin sensitivity and vascular remodeling [2]. In addition, recent observations strongly suggest that activin A signaling plays a major role in the progression of kidney disease and CKD/mineral bone disorder (MBD) [2]. These “off target” actions of MSTN and activin A might contribute substantially to the pathophysiology of wasting, inflammation, vascular damage, and possibly progressive renal dysfunction in CKD
Giacomo, Claudia Di,Acquaviva, Rosaria,Sorrenti, Valeria,Vanella, Angelo,Grasso, Salvatore,Barcellona, Maria Luisa,Galvano, Fabio,Vanella, Luca,Renis, Marcella The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.1
Aerobic exercise increases free radical production as a consequence of enhanced oxygen consumption. If free radical formation exceeds antioxidant capacity, lipids, proteins, and DNA may be oxidized. Oxidative stress is widely recognized as a factor in many degenerative human diseases. The role of dietary antioxidants in protection against disease is a topic of continuing interest. In fact, there is epidemiological evidence correlating a higher intake of nutrients possessing antioxidant abilities with a lower incidence of various human diseases. This study was directed at investigating whether changes in plasma antioxidant capacity and oxidative stress markers occur in voluntary wheel runners, before and after oral supplementation with lycopene and isoflavones. For this purpose, plasma antioxidant capacity and oxidative stress markers were assessed in long distance runners at the end of a 60-minute run. Comparisons were made between runners before and after 60 days of supplementation with lycopene and isoflavones. DNA damage in blood cells of the same samples was also evaluated by comet assay. This investigation shows that oral supplementation with lycopene and soy-derived isoflavones significantly reduced lipid peroxidation and enhanced plasma nonproteic antioxidant defense.
Giacomo Cappon,Martina Vettoretti,Giovanni Sparacino,Andrea Facchinetti 대한당뇨병학회 2019 Diabetes and Metabolism Journal Vol.43 No.4
By providing blood glucose (BG) concentration measurements in an almost continuous-time fashion for several consecutive days, wearable minimally-invasive continuous glucose monitoring (CGM) sensors are revolutionizing diabetes management, and are becoming an increasingly adopted technology especially for diabetic individuals requiring insulin administrations. Indeed, by providing glucose real-time insights of BG dynamics and trend, and being equipped with visual and acoustic alarms for hypoand hyperglycemia, CGM devices have been proved to improve safety and effectiveness of diabetes therapy, reduce hypoglycemia incidence and duration, and decrease glycemic variability. Furthermore, the real-time availability of BG values has been stimulating the realization of new tools to provide patients with decision support to improve insulin dosage tuning and infusion. The aim of this paper is to offer an overview of current literature and future possible developments regarding CGM technologies and applications. In particular, first, we outline the technological evolution of CGM devices through the last 20 years. Then, we discuss about the current use of CGM sensors from patients affected by diabetes, and, we report some works proving the beneficial impact provided by the adoption of CGM. Finally, we review some recent advanced applications for diabetes treatment based on CGM sensors.