동결 건조기의 최적 운전 기법

裵信徹,李近熙 단국대학교 1993 論文集 Vol.27 No.-

The problem of operating a freeze dryer to obtain a fixed final moisture content in minimum time is formulated as an optimal control problem. The energy radated from the heat plate, and total pressure in drying chamber are considered as control variables. Constraints are placed on the system state variables by the scorch point of the dried product and the melting point of the frozen interface. The optimum control policy at the beginning of the run, when neither of the two temperature constraints is active, has been establishen through a theoritical analysis under pseudo-steady state assumptions. For certain cases the nature of the overall optimum control policy has been found. The numerical solution of the steady and nonsteady state problem indicates that if a control policy is optimum for the steady state problem, then this control policy is also optimum for the nonsteady state problem.

다중 중합효소 연쇄반응을 이용한 소의 Johne병 진단 기법 확립

김종배,송혜원,김근희,김홍,신광순,김두 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.1

반추수에서 발생하는 Johne병의 조기 진단 방법을 제시하고 이 질병의 원인체와 미생물학적 특징이 유사한 M. bovis, M. avium 등의 mycobacteria감염증을 감별 진단하는 방법을 개발하기 위하여 Mycobacterium 균속의 표준균주를 사용하여 중합효소 연쇄반응을 확립하였다. Johne병으로 의심되는 소의 혈액과 유즙을 채취하여 분리한 단핵구 및 거식세포로부터 genomic DNA를 추출하였다. 각 시료로부터 추출한 DNA를 template로 이용하여 Mycobacterium spp.에 특이적인 16S rDNA primer set를 이용한 PCR을 수행하여 시료내의 mycobacterial DNA 보유 여부를 확인하였다. 한편 mycobacteria 양성으로 확인된 시료는 M. avium complex 균종에 특이한 16S rDNA 염기서열을 기초로하여 제작한 primer set와 M. paratuberculosis 의 IS900 sequence에 특이한 primer set를 이용하여 duplex PCR을 수행하여 Johne병 원인체의 보균 여부를 조사하였으며, 이 결과를 oligonucleotide probe를 사용한 Southern blot hybridization을 통하여 다시 확인하였다. 이와 같은 duplex PCR 기법을 실제 축산 현장에서 수집한 유즙과 말초혈액으로부터 분리한 단핵구 및 거식세포 시료에 적용한 결과 본 연구에서 확립한 duplex PCR기법 유용성을 확인할 수 있었다. Diagnosis of Bovine Johne's Disease Using Multiplex Polymerase Chain Reactions In order to improve the early diagnosis of Johne's disease in ruminants, duplex polymerase chain reaction system for the detection of the etiologic agent of M. paratuberculosis and for the differentiation of other mycobacterial animal pathogens, such as M. bovis and M. avium, was applied. Genomic DNAs were purified from peripheral blood monocytes or milk macrophages and were used as templates in the duplex PCR. Detection of Mycobacterium spp. in the specimen was carried out by PCR using primer set specific to the mycobacterial 16S rDNA. And then, mycobacterial DNA-positive specimens were further differentiated with duplex PCR system which was composed of primer sets specific to 16S rDNA of M. avium complex and IS900 gene of M. paratuberculosis. The results were re-confirmed by Southern blot hybridization with oligonucleotide specific to the internal sequence of IS900 PCR amplicons. The applicability of this duplex PCR system was evaluated with DNAs extracted from clinical specimens of peripheral blood monocytes and milk macrophages. In summary, the duplex PCR amplification system described in this experiment is promising molecular technique for the early diagnosis of Johne's disease in ruminants.

중량저항운동이 중년 여성의 면역글로블린에 미치는 영향

이배익,박영수,권만근 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

The purpose of this study was to investigate the effect of 12weeks' resistance training on Immunoglobulin in middle aged women. The subjects of this study employed 20 healthy middle aged women in Pu-san city. The study was conducted two (control group, experimental group) by two (pre-test, post-test) factorial design with data analyzed using ANCOVA. The result of this study was not significantly different in IgA, IgD, IgE, IgG, IgM between control group and training group. Therefore moderate weight traning was not change in Immunoglobulin. the following study is profoundly considerated not only immunoglobulin but also mitogen

재발성 다발연골염 1례

이배혁,고의경,왕수건,전경명 釜算慶南耳鼻咽喉科學會 1994 임상이비인후과 Vol.5 No.1

에틸렌 시아노히드린에 의한 실크의 화학적 개질

이근숙,배도규 경북대학교 농업과학기술연구소 2008 慶北大農學誌 Vol.26 No.-

Pad-dry-cure 방식으로 ethylene cyanohydrin을 이용하여 견직물을 acrylonitrile화 시킬때 건조 시간, curing 온도 및 시간, ethylene cyanohydrin처리 농도, ZnCl₂처리 농도 등 조건 변화에 따른 변화와 반응양식을 규명하고자 하였다. 가공된 견직물의 FT-IR과 DSC 분석을 통하여 다음과 같은 결과를 얻었다. Curing을 150 ℃에서 2분, ethylene cyano hydrin 처리농도 5%, ZnCl₂처리농도 0.1%, 건조 온도를 80 ℃로 하여 건조 시간 경과에 따른 견직물의 FT-IR 분석 결과, 건조 시간 경과에 따라 -0H(3,450cm^(-1)) 특성 peak가 전부 장파장 쪽으로 shift 되어 나타 났고, random coil에 의 한 amide peak(1,663cm^(-1))는 단파장 쪽으로 shift되어 β-sheet peak(1,635cm^(-1))와 중복되어 나타났다. 건조를 8℃에서 3분, curing을 110℃에서 2.5분, ZnCl₂농도를 0.1%로 하여 eylene cyanohydhn처리 농도에 따른 가공 견직물의 FT-IR 분석에서 -OH(3,450cm^(-1))특성 peak에서 변화가 나타나 견직물의 -OH기가 반응에 관여하고 있는 것을 알 수 있었다. 위와 같은 조건으로 가공된 견직물의 DSC 분석에서 eylene cyanohydnn처리에 의해 견직물의 열분해 온도는 무처리의 311'C에서 대략 320 "C로 상승하는 것으로 나타났다. 건조를 80'C에서 3분, curing을 110'C에서 2.5분, ethylene cyanohydrin 처리농도 5%로 하여 ZnCl₂처리 농도에 따른 가공 견직물의 FT-IR 분석에서는 촉매 처리농도 0.8%일 경 우를 제외하고는 -OH(3,450cm^(-1))특성 peak에서 대부분 무처리와 비슷한 결과를 보여주고 있으나, 0.8%의 경우에는peak에 큰 변화를 나타냈다. 같은 조건에서 가공된 견직물의 DSC 분석에서, ethylene cyanohydhn 처리에 의해 견직물의 열분해 온도는 촉매농도와는 관계없이 무처리(311'C)에 비해 가공 견직물(대략 320'C)의 열분해 온도가 상승점을 알 수 있었다. 건조를 80 "C에서 70초, eylene cyanohydrm처 리 농도 5%, ZnCl₂처리농도 0.8%, Curing시간을 2.5분으로 하고 curing 온도를 각각 110, 120, 130, 140, 150, 160 ℃로 변화시켜 가공한 견직물의 FT-IR의 분석 결과, curing 온도 110, 150, 160℃에서 -OH특성 peak의 변화가 크게 나타났다. 같은 조건으로 가공한 견직물의 DSC분석에서는 ethylene cyanohydrin 처리에 의한 견직물의 열분해 온도는 curing 온도에 상관없이 미처리구(311℃)에 비해 전부 열분해 온도(대략 320℃)가 상승함을 알 수 있었다. In this paper, when the silk fabric was modified by ethylene cyanohydrine, the reaction mechanism between both was studied at various treatment conditions such as curing temperatures and times, ethylene cyanohydrin concentrations and ZnCl₂concentrations. Through the FT-IR and DSC analyses of the treated silk fabrics, we found the results as follows : It was observed in FT-IR analysis of the treated silk fabrics that the -OH characteristic peak(3,450 cm^(-1))position and shape were all changed when drying and curing treatment conditions were at 80℃ for 3 minute and 110℃ for 2.5 minute, and the concentration of the ZnCl₂ was 0.1%. It indicated that the -OH group of the silk participated in the reaction between the silk fabric and ethylene cyanohydrin . From the DSC analysis, it was found that the pyrolysis temperatures of the treated silk fabrics by ethylene cyanohydrin which was processed in the same condition, were all increased from 311℃ to ab. 320 ℃. From the FT-IR analyses of the silk fabrics treated by ethylene cyanohydrin at the various concentrations of ZnCl₂, it was found that the -OH characteristic peaks(3,450 cm^(-1)) were similar to the nontreated one except that of the fabric treated at the ZnCl₂conconcentration of 0.8% when drying and curing treatment conditions were at 80℃ for 3minute and 110℃ for 2.5 minute, and the concentration of the ethylene cyanohydrin was 5%. In the case of the ZnCl₂ concentration of 0.8% soultion, a lot of change were observed in peak. From the DSC analysis of the treated silk fabrics which was processed in the same condition, it was showed that the pyrolysis temperatures of treated silk fabric were all increased from 311℃ to ab. 320℃, which was no relation with the concentration of ZnCl₂.

<李娃傳>의 분석심리학적 연구

허근배 한국인문과학회 2006 人文學論叢 Vol.5 No.2

This thesis is on analyzing The Biography of LiWa<李娃傳> through Analytical Psychology and looking for deep meaning about it. C.G.Jung, the originator of Analytical Psychology, believed that the final aim of living is Self-actualization for combining one's consciousness and unconsciousness. This work shows how the main character LiWa(李娃) and ZhengSeng(鄭生), accomplishes Self-actualization. In this novel, the ego(自我) and the persona(面) in four persons' characters have appeared well. both XingYangGong(滎陽公) and JiMu'(枝姥) persona has suggested the conflict factor which a man-and-woman hero has to experience from the contents of the novel spread out. although LiWa is a partner about aristocrats with the status of a singing and dancing girl(枝妓) even if and saved much money, she gets married, she bears a child, and wants to raise. ZhengSeng(鄭生) got a lot of expectation of father. but he thinks that he will escape from the figure of the ego which is in sight externally. If feminine Animus realizes anything, it helps to a crucial inner companion so as to have courage, objectivity, manly tempers such as spiritual wisdom. perfect from feminine tempers a man is recognized about relation through integrations of Anima better, and to be inner is the same as what can create. The Biography of LiWa is a work expressed mental consciousness brazier humanitarianism of man and woman main character. if we look into center trouble of a novel, firstly an obstacle to stop up the accomplishment of affection is not the class or government authority, and be re-water LiWa or JiMu can know wicked thing. There is creative intention of The Biography of LiWa to a humanity recovery and faithfulness of LiWa when we see through this. Therefore, The Biography of LiWa is a story LiWa recovering humanity through consciousness anger, and there to be a focus by status rise through a trouble of monistic contradiction and polarity of the human existence.

급속 열처리시킨 n-GaAs에서 Photoreflectance 연구

김인수,배인호,최재두,김근형 嶺南大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.17 No.-

The characteristics of rapid thermal annealed n-GaAs(100) is analyzed by the photoreflectance(PR) measurement. The Si highly doped n-GaAs was observed the FKO signals. The bandgap(E?) and surface electric field(E?) of as-grown sample were 1.423 eV and 2.65×10? V/cm, respectively. In the rapid thermal annealed samples, E? was increased and then decreased by increasing anealing temperature, and it was increased again at 800 ℃. These results could be explained by decreasing of the non-radiative recombination on samples. For the time dependence of the rapid thermal annealing, the amplitude of the PR signal was maximum at 20 sec, and E? was increased by 10.7 times than that of as-grown sample.

동국대학교 부속병원에서 진단된 암환자의 특성

김두희,임현술,배근량 동국대학교 의학연구소 1999 東國醫學 Vol.6 No.-

국 문 초 록동국대학교 의과대학 부속 경주병원과 포항병원에서 1996년 1월 1일부터 1997년 12월 31일까지 2년간 암으로 진단 받아 보건복지부 한국중앙암등록본부에 보고하였던 경주병원 암환자 426명(남자 256명, 여자 170명)과 포항병원 암환자 196명(남자 112명, 여자 84명), 총 622명(남자 368명, 여자 254명)을 대상으로 암의 일반적인 특성을 파악하고 전국 암등록자료와 비교 분석하였다. 연구 방법은 암등록 조사보고서를 검토하여 대상자 선정을 한 후 암 환자의 일반적 특성을 조사하였다.암 환자의 평균 연령은 남자는 61.6±14.6세이었고 여자는 59.7±16.2세이었다. 연령 분포는 남녀 모두 70대 이상이 가장 많았고, 60대, 50대, 40대의 순이었다. 거주 지역별 분포는 양 병원 모두 지역 환자가 90% 이상을 차지하였으며 외부에서 환자의 유입이 거의 없었다. 원발부위의 병원별 분포는 여자에서는 차이가 없었으나 남자에서는 경주병원에서 폐암과 방광암이 유의하게 많았다(p<0.05). 전국 암등록자료와 비교하면 남자에서는 폐암과 방광암의 빈도가 높았으나 여자에서는 전국 암등록자료와 유사한 분포를 보였다. 원발부위별 성별 평균연령은 남자에서 위암 62.3±12.2세, 폐암 67.8±8.3세, 간암 56.6±12.5세, 대장암 56.0±15.0세, 방광암 68.0±10.8세, 여자에서 위암 63.4±13.2세, 자궁경부암 50.2±16.0세, 대장암 62.2±13.0세, 간암 63.6±14.4세, 유방암 49.0±9.2세로 남자에서는 간암과 대장암이 여자에서는 자궁경부암과 유방암의 평균 연령이 낮았다. 암 진단방법에 병원간 차이는 발견할 수 없었으나 성별 조직학적 검사 실시율이 남자는 74.5%, 여자는 83.1%로 여자의 실시율이 높았으며, 전국 암등록자료의 남자 79.3 %, 여자 86.8%에 비하여 낮았다. 암환자의 치료방법은 병원별 차이는 없었으나, 성별로는 여자에서 수술 실시율이 유의하게 높았다(p<0.01). 원발부위별로는 수술 실시율이 전국 암등록자료와 비교하였을 때 위암, 대장암, 폐암의 수술 실시율은 낮은 반면, 방광암, 자궁경부암, 유방암의 수술 실시율은 다소 높았다.본 조사는 2년간의 자료를 분석하였으므로 암의 특성에 관한 연도별 변화를 보기에는 어려움이 있었다. 앞으로 매년 자료를 수집하여 계속적으로 분석을 시도하는 노력이 필요하다고 생각한다.AbstractThis study was performed to evaluate the characteristics on 662 cases of cancer registered (male 368 cases, female 254 cases) in two Dongguk University Hospitals from January 1, 1996 to December 31, 1997. We obtained the reports of cancer registries in two hospitals and compared them with annual report of the Central Cancer Registry Center in Korea. The results obtained were as follows.The mean age of cases of cancer was 61.6±14.6 years in male, 59.7±16.2 years in female. The most frequent age group in the order of relative frequency was 70 and above, followed by 60∼69, 50∼59, and 40∼49 years of age in both sex groups. The most frequent places of residence was Kyongju or Pohang city(above 90%).In male, the primary sites of cancer in the order of relative frequency was stomach (28.0%), followed by lung (20.7%), liver (13.9%), urinary bladder (6.3%) and colorectum (6.3%). In female, the primary sites of cancer in the order of relative frequency was stomach (26.0%), followed by uterine cervix (11.8%), colorectum (10.2%), liver (7.1%) and breast (6.3%). The mean age of primary site of cancer was stomach 62.3±12.2 years, lung 67.8±8.3 years, liver 56.6±12.5 years, colorectum 56.0±15.0 years and urinary bladder 68.0±10.8 years in male. In female, The mean age of primary site of cancer was stomach 63.4±13.2 years, uterine cervix 50.2±16.0 years, colorectum 62.2±13.0 years, liver 63.6±14.4 years and breast 49.0±9.2 years. The relative frequency of cases diagnosed by the pathologic examination were higher in female (83.1%) than in male (74.5%)(p<0.05). The positive rate of operation were higher in female (52.8%) than in male (31.0%)(p<0.01). There were no difference of diagnostic and treatment methods between hospitals.

대구경 현장타설말뚝에 대한 수평재하시험 및 말뚝 깊이별 수평변위분포에 대한 연구

이민희,황근배,정성민,최용규 경성대학교 공학기술연구소 2003 공학기술연구지 Vol.S2 No.1

Most of pile foundations are a condition of fixed head on pile, but lateral loading test of pile have performed to free head on generally This study performed field lateral loading test accompanying lateral displacement by depth of pile for two cases(fixed head and free head) and analyzed lateral behavior of large drilled shaft. Further more compared theoretical equation with result of lateral loading test.

인체 Calbindin-D9k 항체 제작과 종특이적 활성

이근우, 홍의주, 이근식, Vu-Hoang Dang, 정의배 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

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