Interleukin-2가 호산구 생존에 미치는 영향과 기전에 관한 연구

김효석 ( Hyo Seok Kim ),이영목 ( Young Mok Lee ),최영수 ( Young Soo Choi ),김경호 ( Kyung Ho Kim ),임건일 ( Geon Il Im ),문승혁 ( Jeong Sung Whan ),정성환 ( Moon Seung Hyug ),김현태 ( Hyeon Tae Kim ),어수택 ( Uh Soo Taek ),김용훈 대한결핵 및 호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.3

Model Checking for Binary Response Data : Beetle Mortality Example

하일도,조건호,최명희 慶山大學校 1997 論文集 Vol.15 No.1

본 논문은 통계패키지 GENSTAT macro에 근거한 K-system(1996)에서 제공해주는 모형검토를 활용하여, Bliss(1935)에 의해 소개된 딱정벌레 사망율자료(Beetle mortality data)에 대한 적절한 모형을 찾는 방법을 연구한다.

경제적 자동화투자를 위한 결정요인의 평가

유일근 弘益大學校 科學技術硏究所 1995 科學技術硏究論文集 Vol.6 No.-

The factory automation is considered so far as a beneficial investment to run a company. However, it is not always true. For the analysis for this problem, the factors which have important effects to make the costs and benefits in the investment of facility automation were collected and investigated. And the method of their quantitative and qualitative analyses for monetary evaluation is proposed. The monetary conversion process in this paper would make it possible to calculate the approximate value of both losses an gains which are derived from the FA investment. It would help not overestimate the advantages and underestimate the risk from the automation investment.

遲延이 許用된 設備增設의 經濟的 硏究

兪日根 弘益大學校 1990 弘大論叢 Vol.22 No.2

When growth in demand for goods or services takes place, it tends to be continuous, while the growth in total facility capacity tends to be available only in discrete steps. This paper deals the problem how to determine the size of the addition(Economic package) or the frequency of addition(Economic interval) that maximizes profit when total facility capacity should be expanded in discrete steps according to the growth of demand. Here, small and frequent additions have advantages to avoid idle capital and large units tend to have smaller initial costs. To determine the economic interval and package, the possibilities of the delay of facility addition below the demand size and the penalty of it are added in the consideration and analysis. This consideration results in different economic interval and size in the minimization of total costs of operation.

일반화된 지수생존모형의 추정

하일도,조건호 慶山大學校 基礎科學硏究所 1999 基礎科學 Vol.3 No.-

일반화된 지수생존모형(peneralized exponetial survival model)을 고려하여 이 모형의 모수를 추정하는 수정된 FS(modified Fisher scoring)방법을 제안한다. 이를 위해 우도방정식(likelihood equations)을 유도하고 초기추정치(initial estimate)를 포함한 추정알고리즘(estimating algorithm)을 개발한다. We consider generalized exponetial survival model and propose a modified Fisher scring method which estimates the model parameters. Also, the fitting algorithm including an initial estimate is developed.

제2형 당뇨병 환자에서 체내 총항산화능 측정의 의의

윤여일,윤석기,김선규,김용현,남일송,차건영,황의원,김영선 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: The diabetic patients are at significantly increased risk of developing vascular disease. It's etiology may involve oxidative damage by free radiacals and protection againse such damage can be offered by antioxidants. We investigated that oxidative stress as assessed by measurement of total antioxidant status may play a role in development of diabetes mellitus. Method: We measured total antioxiant status using merchandised kit, glycated hemeglobin(HbA1c) in 46 type 2 diabetes mellitus patients and 50 healthy matched control subjects. Result: The total antioxidant status(TAS) was 2.10(±0.04) mmol/L in uncontrolled type 2 DM patients, 2.60(±0.03) in controlled type 2 DM patients and 2.70(±0.16) in healthy control subjects. TAS was significantly lower(P<0.05) in uncontrolled type 2 DM patients, but no significant association between in controlled type 2 DM patients and healthy control subjects. The TAS was 2.00(±0.17) mmol/L in complicated type 2 DM patients and 2.10(±0.29) uncomplicated type 2 DM patients. There was no significant associations between complicated type 2 DM patients and uncomplicated type 2 DM patients. Conclusion: Poor glycemic control is associated with reduced TAS in type 2 DM patients. TAS was thought indirect index that predict glycemic control of type 2 DM patients.

지수분포를 따르는 가속수명자료의 적률추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 적률추정량에 기초한 불편추정량(unbaised estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

폐혈관상이 유지된 선천성 낭성 선종양 기형

배일헌,한기석,차상훈,김성진,박길선,이건국,홍장수 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

선천성 낭성 선종양 기형은 태생 16주 이후 말단세기관지의 형성이 중단되어 미성숙기관지들과 중배엽성분들이 과도하게 증식하여 발생하는 드문 선천성 폐질환이다. CT소견은 낭종의 크기 숫자, 내용물 등에 따라 다양하나, 병변내에 정상적인 폐혈관이 보인 예는 전세계적으로 보고된 적이 없었다. 저자들은 역동적 흉부 CT상 균일한 저음영의 병변내에 정상 폐혈관상이 유지된 선천성 낭성 선종양 기형 1예를 경험하였기에 보고한다. Congenital cystic adenomatoid malformation(CCAM) is a rare pulmonary disease that is thought to be developed by abnormal proliferation of immature alveoli and other mesenchymal component from the abrupt halting of the terminal alveoli formation after 16 weeks of gestation. On CT scan, there are no consistencies regarding to size, numbers, and its contents but no cases were reported in past showing normal pulmonary vascularities. We reports a case of CCAM that showed normal pulmonary vascularities within the hypodense lesions on a dynamic chest CT

지수분포를 따르는 가속수명자료의 최우추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 최우추정량(Maximun Likelihood estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

기술자산평가를 위한 점수산정법의 개발

유일근,신정태 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-

Since the technology is one of the most important factors for national and cooperate competition, the development of new and profitable technologies is highly emphasized. Then the question occurs for the new technology as how much it would be profitable and valuable. To solve such a problem the Point assessment system(PAS) is developed in this paper. The PAS would provide sales price and mortgage value for technology assets. For this purpose, this paper include the analysis of existing PA methodologies throughout the world to find the differences and features to make new and improved assessment factors. In order to enhance objectivity of qualitative characteristics of technology, PAS suggests 10 factors for assessment. The 10 factors were divided into three groups that consist of technology feature, technology environment and economic environment. Various pointing questionnaires are provided for each 10 assessment factor in order to calculate the total grade and value of the given technology.