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      • 건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

        박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

        Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

      • Ni-Zn 페라이트의 透磁率과 磁氣抵抗에 미치는 添加物의 影響

        강재덕,최희태,서강수,신용진 明知大學校 産業技術硏究所 1990 産業技術硏究所論文集 Vol.9 No.-

        This paper is studied on the effects of additive of permeability and magnetic reluctance of Ni-Zn ferrites. Ni-Zn ferrites was composed of 20mo1% NiO, 30mo1% ZnO, 50mo1% Fe₂O₃, and 0.0025n1o1%, 0.005mo1%, 0.01 mol% ??, Bi₂O₃, ?? were used as minor additive Sintering was carried oui at 1100℃. As results from the experiments, the initial permeability was proportional inversely to magnetic reluctance. It was observed that the better magnetic properties of initial permeability anti magnetic reluctance could be achieved by the additive ??.

      • 일차배양된 설치류 호흡기 상피세포로부터의 점액소 분비에 대한 수종 약물의 영향

        이충재,석정호,이재흔,허강민,박지선,배소현,노삼길,박상철 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

        1. PKC activator인 PMA는 일차배양 HTSE세포로부터의 뮤신분비를 0.1μM 농도에서 30%, 1μM 농도에서 80% 가량 증가시켰다. 2. 식물 유래 성분으로, flavonoid의 일종인 TFR은 일치배양 HTSE 세포로부터의 뮤신분비를 10μM 농도에서 50%, 100μM 농도에서 80% 가량 증가시켰다. 3. 양이온성 폴리펩티드인 PLL 및 PLA는 일차 배양 HTSE 세포로부터의 뮤신분비를 0.01 - 10μM 농도에서 용량의존적으로 감소시켰다. 4. 결론적으로, 본 연구에서 얻어진 결과들은 새로운 거담제 및 점액용해제나 단백분해 효소제가 아닌 호흡기 류신의 생성/분비를 조절해 줄 수 있는 신개념의 약물을 개발함에 있어 극히 일부분이나마 단서를 제공하고 있다고 하루 수 있을 것이다. In the present study, we tried to investigate whether phorbol myristate acetate(PMA), trihydroxymethoxy-flavanone rutinoside(TFR) and cationic polypeptides significantly affect mucin release(secretion) from cultured hamster tracheal surface epithelial cells. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with 3H-glucosamine for 24 hr and chased for 30 min in the presence of each agent to assess the effect on 3H-mucin release. The results were as follows : (1) Both PMA and TFR significantly increased mucin release from cultured HTSE cells ; (2) Cationic polypeptides including po1y-L-lysine(PLL, mw 7,500) and poly-L-arginine(PLA, mw 10,800) significantly inhibited mucin release from cultured HTSE cells, in a dose-dependent manner. This finding suggests us that PMA and TFR be further studied for the possible use as mild expectorants and cationic polypeptides might function as a regulator for hyper-secretion of mucus, both by direct acting on airway mucin-secreting cells, during the treatment of chronic airway diseases.

      • 재생간의 성장과정에 따른 ^3H-ouabain의 결합에 관한 연구

        이재흔,허강민 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

        To study the changes of Na, K-ATPase in the regenerating liver cell prepared the sinusoidal and canalicular membrane from normal and regenerating rat liver after partial hepatectomy, and Na, K-ATPase activity and ^3H-ouabain binding were measured. 1. In the control liver, Na, K-ATPase activity of sinusoidal membrane was 23.8μmole Pi/mg protein/hr and that of canalicular was 7.0 μmole Pi/mg protein/hr. But the numbers of ^3H-ouabain binding sites were almost same in both membranes. 2. In the regenerated liver for 3 days, the activity of Na, K-ATPase of sinusoidal membrane was decreased about 50% as compared to that of control liver. 5 days after partial hepatectomy, the activity of Na, K-ATPase was restored. 3. Ouabain concentration for the inhibition of Na, K-ATPase activity(IC_50) of sinusoidal membrane in the regenerated and control liver were 5.0 X 10 exp(-5)M and 3.8 X 10 exp(-5)M respectively. 4. In the ouabain binding experiment of sinusoidal membrane, there were little difference in Kd values between both group, but B_max in the regenerated liver was decreased about 50% compared to that of control liver. From the above results, it is suggested that the decreased Na, K-ATPase activity in the sinusoidal membrane during regeneration is due to the decreased numbers of ouabain binding sites, and Na, K-ATPase is distributed in canalicular membrane as well as sinusoidal membrane.

      • KCI등재

        조식과의 대비적 관점에서의 최영경 문학 연구

        전재강 한국어문학회 2004 語文學 Vol.0 No.85

        Choi, Young-kyung was known as one of Jo, Sik's best students. He played an important role as Jo, Sik's successor in his life style, literature, literary criticism, Chinese poetry, and prose. The purpose of this study is to analyze Choi, Young-kyung's literature in comparison with the literature of Jo, Sik, in the hope of understanding Choi, Young-kyung's literature and the whole Jo, Sik school of literature more deeply. First, this study compares Choi, Young-kyung's and Jo, Sik's literary criticism. Choi, Young-kyung adopted his teacher's style of literary criticism, in which The Principle must be expressed in an literature and The Principle itself must be regarded as of more importance than the literary expression(as opposed to the viewpoint of an earlier group of Confucian scholars). But his literary criticism differed from his teacher's in regard to the specific contents of The Principle which could be expressed in literature and the level of importance ascribed to it. His view of how The Principle of Confucianism must be expressed in literature differed from his teacher's belief that several kinds of ideologies -for example, Confucianism, Buddhism, and Taoism-could be expressed in literature at the same time. And in the level of balance between The Principle and its expression, Choi, Young-kyung insisted that The Principle itself must be regarded as of more importance than the literary expression comparing to his teacher's. Next, this study looks at the contents of Chinese poetry in respect to its ideology and its themes of resigning from and remaining in office. Choi, Young-kyung succeeded his teacher by expressing Confucianism as the main element in his Chinese poetry. But his poetry differed from his teacher's in that, while Choi, Young-kyung only delineated Confucianism, his teacher also expressed other ideologies in his poetry. In his poetry, Choi, Young-kyung agrees with his teacher's belief that resigning from office is important, but differs from his teacher in this regard in his specific actions. While Choi, Young-kyung was cultivating his nature while resigning from office according to Confucianism only, his teacher also related (as well as Confucianism) Buddhism and Taoist transcendence to this. These distinctions stemmed from what Choi, Young-kyung learned from his teacher's spirit of propriety, which was based on Confucianism. Third, this study looks at the rhetorical devices of Chinese prose. In his Chinese prose, Choi, Young-kyung inherited his teacher's simple rhetorical devices, such as example, direct description, narration, explanation by definition, syllogism, cause and effect, etc. In his prose, however, he did not use his teacher's highly rhetorical devices, such as indirect criticism, reconstruction of ancient history, ironic construction, and climax. He believed that important ideas could be transmitted to the readers logically, exactly and without misunderstanding, by using simple rhetorical devices, while his teacher's intention, in his prose, was to move the reader's mind and transmit a message to them emotionally through the use of highly rhetorical devices. Lastly, the characteristic faces of Choi, Young-kyung's literary criticism, Chinese poetry, and prose, as discussed in the main discourse, are shown to be very important in respect to literature, ideology, and history. As his literature is representative of literature concerning people resigning from office, and he is more inflexible than his teacher's generation in ideology, Choi, Young-kyung's action in his life and literature is meant to realize his teacher - Jo, Sik's practical lessons from within Jo, Sik's school. More remains to be looked at. Literary criticism, Chinese poetry, and prose must be studied more deeply. More comparative study between Choi, Young-kyung and other students of Jo, sik's school is also needed in order to ascertain what students of this generation have in common.

      • KCI등재

        김인후의 문예 의식과 그 시조문학의 성격

        전재강 한국어문학회 2004 語文學 Vol.0 No.83

        In-hoo Kim was very famous in Korea as a neo-confucian scholar and poet during the Chosun dynasty. He composed many Chinese poems. In addition, he wrote three Korean poems, these are referred to as Sijo. In order to understand his Sijo, I first analysed his literary criticisms. Formally he thought literature should be useful for teaching people Confucianism. But in reality he showed a different literary attitude while composing his poetry, expressing his passion which stemmed from daily life in a complicated world. Thru expressing his mental agony he obtained a measure of peacefulness and happiness. Emotionally he thought literature should be useful for solving psychological problems. These two different literary criticisms are harmonized into one higher form of literary criticism. According to his high lebel literary criticism, expressing mental agony and solving psychological problems can be the same as teaching people Confucianism. He wrote about 1,600 Chinese poems throughout his life. These Chinese poems can be classified into four groups expressing different themes. In the first group, the ontology of traditional Confucianism was represented. The method of learning Confucianism was dealt with in second group. The general emotions of human beings were the topic of group three and finally, the fourth group described the scenery. In-hoo Kim's Sijo can be classified into the third category of man's general emotions. His resolution to overcome agony in his daily life and his intention to be devoted to nature are described in his Sijo. These can not be described in Chinese poems and Korean poems because his emotions violate the tone of traditional moderation. By comparing his Sijo with those of his teachers, students and friends, I came to understand his poetry more precisely. In-hoo Kim took nature, for example mountains and rivers, as subject matter in his Sijo just like those of his contemporaries but expressed his passion by using nature as subject matter differently than the others. This is evident in his teacher Song Soon's expression of peaceful mind and his friend Lee Hwang's neo-confucian thinking.

      • KCI등재

        만성 요통근로자의 능동적 운동프로그램 효과

        허진강,송재철,노영만,박동식,양영애,김윤신 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.1

        목적: 본 연구는 만성 요통근로자의 세 가지 능동적 운동프로그램 효과에 관한 연구로서 능동적 운동이 요추의 안정성 향상에 미치는 영향을 알아보고자 시도되었다. 방법: 3개월 이상 만성요통을 호소하는 64명의 근로자대상으로 무작위로 일반적인 물리치료그룹, 요추 운동그룹, 흉추 운동그룹, 세 그룹으로 나누었다. 능동적 운동 프로그램은 주 3회, 6개월 동안 실시하였으며, 통증강도, Oswestry 장애지수, 양손을 머리위로 최대한 올려 높이 측정, 요추부 경사각도를 평가하였다. 모든 대상자들은 연구 전, 연구 후 2주, 3개월, 6개월을 같은 측정방법으로 재평가하였다. 결과: 통증강도는 세 그룹 간에 통계적으로 유의한 차이가 없었다. Oswestry 장애지수는 연구 후 6개월에서 세 그룹 간의 유의한 차이가 있었으며, 요추운동그룹과 흉추운동그룹이 일반적인 물리치료그룹에 비하여 유의하게 감소하였다(p<0.05). 양손을 머리위로 최대한 올려 높이측정은 연구 후 3개월과 6개월에서 세 그룹 간에 유의한 차이가 있었으며, 연구 후 6개월에서는 흉추운동그룹이 일반적인 물리치료그룹과 요추운동그룹에 비하여 유의하게 증가하였다(p<0.05). 요추부 경사각도는 연구 후 2주와 3개월, 6개월에서 세 그룹 간에 유의한 차이가 있었으며, 연구 후 6개월에서는 흉추운동그룹이 일반적인 물리치료그룹과 요추운동그룹에 비하여 유의하게 감소하였다(p<0.05). 결론: 3개월 이상 만성 요통을 호소하는 근로자 대상으로 흉추의 운동성 증가를 위한 운동프로그램을 적용하여 흉추의 운동성을 증가시킨 결과에서 보면, 2주 시행하였을 때 요추의 신전 운동프로그램 보다 요추의 안정성 향상에 효과적이며, 6개월 시행하였을 때만, 요추의 심부근 근력강화 운동프로그램보다 요추의 안정성 향상에 효과적이었다. Oswestry 장애지수는 요추의 심부근 근력강화 운동프로그램과 동일하게 감소하였고, 통증강도는 세 그룹 모두 2주 시행하였을 때 감소하는 것으로 나타났다. Objective: To examine the relative efficacy of three active exercise programs for work-related, chronic low back pain, and to observe to what extent the programs affected the mechanical stability of the lumbar region. Methods: The subjects were 64 employees who were randomly divided into three groups to match the three active exercise programs which were performed 3 times a week for 6 months. All subjects were assessed with the same measurements at a pre-study examination, and then were reassessed at 2 weeks, 3 months and 6 months after the study. Results: The pain intensity didn' t show any significant difference among the three groups. However, the Oswestry Disability Index showed significant differences among the three groups at 6 months and the lumbar and thoracic exercise groups showed significant decreases compared to the general physiotherapy group (p<0.05). Maximal stretching with both hands in the overhead direction showed a significant difference among the three groups at 3 months and 6 months, and the thoracic exercise group at 6 months showed a significant increase in overhead stretching compared to the lumbar exercise and general physiotherapy groups (p<0.05). The lumbar region angle of inclination showed significant differences among the three groups at 2 weeks, 3 months and 6 months, with the thoracic exercise group being decreased significantly more than the lumbar exercise and general physiotherapy groups at 6 months (p<0.05). Conclusions: Exercise aimed at increasing thoracic mobility has an effect on lumbar stability. Furthermore, it is far more effective for lumbar stabilization than general physiotherapy and deep muscle strengthening lumbar exercise.

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