인터넷시대의 공공도서관

Freedman, Maurice J. 한국도서관협회 2006 圖協會報 Vol.47 No.9

인터넷시대에서 공공도서관은 도태할 것인가. 아니면 새로운 황금기를 맞이할 것인가? 이에 대해 적절한 대답과 사례를 제공하는 글이 있어 이번 호에 게재한다. 이 글은 지난 8월17일 부산광역시립시민도서관에서 열린 2006서울세계도서관정보대회 개최 기념 세미나에서 발표된 내용을 번역한 것이다. 강연자 프리드만 박사(Dr. Mourice J. Freedman)는 미국 도서관협회(ALA)의 회장과 미국 뉴욕 웨스트체스터 카운티의 도서관장을 역임하였다. 이 글의 원문은 미국 국무성에서 펴내는 전자저널(2006년 3월호)에 실려 있다.(http://usinfo.state.gov/journals/itgic/0306/ijge/freedman.htm)

Perspectives on the Future of the Family Planning Program of Taiwan

Freedman, Ronald,Freedman, Deborah The Population Association of Korea 1993 한국인구학 Vol.16 No.1

Does Recombinant Human Bone Morphogenic Protein 2 Affect Perioperative Blood Loss after Lumbar and Thoracic Spinal Fusion?

Brett Freedman,Bayard Carlson,William Robinson,Mohamad Bydon,Michael Yaszemski,Paul Huddleston,Brett Freedman 대한척추외과학회 2018 Asian Spine Journal Vol.12 No.5

Study Design: Retrospective cohort design. Purpose: This study aimed to determine whether recombinant human bone morphogenic protein 2 (rhBMP-2) reduces total perioperative blood loss during lumbar and thoracic fusion. Overview of Literature: Previous studies on rhBMP-2 versus iliac crest bone grafting in thoracic and lumbar fusions have yielded mixed results regarding reductions in blood loss and have largely neglected the postoperative period when analyzing total blood loss. Additionally, these studies have been limited by heterogeneity and sample size. Methods: We analyzed the blood loss patterns of 617 consecutive adult patients undergoing lumbar and/or thoracic fusions requiring subfascial drain placement at a single institution from January 2009 to December 2016. Patients were divided into BMP and non-BMP cohorts, and a propensity score analysis was conducted to account for the differences between cohorts. Results: At a per-level fused basis, the BMP group exhibited a significant reduction in the intraoperative (66.1 mL per-level fused basis; 95% confidence interval [CI], 127.9 to 4.25 mL; p =0.036) and total perioperative blood loss (100.7 mL per-level fused basis; 95% CI, 200.9 to 0.5 mL; p =0.049). However, no significant differences were observed in an analysis when not controlling for the number of levels or when examining the postoperative drain output. Conclusion: RhBMP-2 appears to reduce both intraoperative and total blood loss during lumbar and thoracic fusions on a per-level fused basis. This total reduction in blood loss was achieved via intraoperative effects because RhBMP-2 had no significant effect on the postoperative drain output.

Perspectives on the Future of the Family Planning Program of Taiwan

Ronald Freedman,Deborah Freedman 한국인구학회 1993 한국인구학 Vol.16 No.1

1. The future service tasks of the family planning program will be primarily in the social welfare rather than in the demographic arenas. There are still important things to be done in maintaining and improving the quality of family planning services. The emphasis in general is ikely to be on the quality rather than on the quantity of population. 2. Taiwan could take the lead in developing and testing service models, including both the private and public sectors, for countries with mature programs, low fertility, and strong private sectors. 3. Taiwan's fertility is likely to be within a ow fertility range, e.g., 1.6 to 2.4, for some time to come, like other developed countries. if Values within this range inevitably mean substantial aging of the population, creating probems with respect to care for the elderly and the supply of entry-level labor force members. 4. While our preference is for the replacement-level fertility that is inevitable in the long run, we are skeptical that deliberate fine-tuning of the fertility level within the low-fertility range s possible on the basis of present knowledge and especially in a free society. Policies to deal with the consequences of low fertility are likely to be more important than attempts to increase fertility. However, it is important that Taiwan should have a program of research on factors affecting fertility within the low-level range that characterizes developed countries. 5. While the family planning program is relevant, the policy issues arising from the consequences of low fertility will mainly be the responsibility of other agencies working together. 6. Finally, we have suggested, for serious consideration, possible organizational changes. These involve : a. shifting some service functions to the private sector; b. integrating other governmental family planning services with maternal and child health services; c. elevating the research functions of the Provincial Institute of Family Planning to a national-level, broadbased Institute for Research on Population and Health.

Treating Angina : Choosing the Most Appropriate Therapy

Freedman, Ben Medical Publications Korea 1988 Medical Progress Vol.10 No.3

Detection of Long and Short DNA Using Nanopores with Graphitic Polyhedral Edges

Freedman, Kevin J.,Ahn, Chi Won,Kim, Min Jun American Chemical Society 2013 ACS NANO Vol.7 No.6

<P>Graphene is a unique material with a thickness as low as a single atom, high in-plane conductivity and a robust lattice that is self-supporting over large length scales. Schematically, graphene is an ideal solid-state material for tuning the properties of a nanopore because self-supported sheets, ranging from single to multiple atomic layers, can create pores with near-arbitrary dimensions which can provide exquisite control of the electric field drop within the pore. In this study, we characterize the drilling kinetics of nanopores using a thermionic electron source and various electron beam fluxes to minimize secondary hole formation. Once established, we investigated the use of multilayer graphene to create highly tailored nanostructures including nanopores with graphite polyhedral crystals formed around the nanopore edge. Finally, we report on the translocation of double stranded and single stranded DNA through such graphene pores and show that the single stranded DNA translocates much slower allowing detection of extremely short fragments (25 nucleotides in length). Our findings suggest that the kinetic and controllable properties of graphene nanopores under sculpting conditions can be used to further enhance the detection of DNA analytes.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-6/nn4003665/production/images/medium/nn-2013-003665_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn4003665'>ACS Electronic Supporting Info</A></P>

Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study.

Freedman, Barry I,Bowden, Donald W,Ziegler, Julie T,Langefeld, Carl D,Lehtinen, Allison B,Rudock, Megan E,Lenchik, Leon,Hruska, Keith A,Register, Thomas C,Carr, J Jeffrey Mary Ann Liebert, Inc 2009 Journal of bone and mineral research Vol.24 No.10

<P>Inverse relationships have been observed between BMD and vascular calcification (VC), suggesting an underlying metabolic pathway linking these processes. Bone morphogenetic proteins (BMPs) are potential candidate genes that may mediate this relationship. Four single nucleotide polymorphisms (SNPs) in the BMP2 gene, 2 SNPs in BMP4, and 16 SNPs in BMP7 were tested for association with measures of VC using CT (coronary and carotid arteries, abdominal aorta), and BMD was measured using DXA (lumbar spine, hip, and distal radius) and quantitative CT (QCT; thoracic and lumbar spine) in 920 European Americans from 374 Diabetes Heart Study families: 762 with type 2 diabetes. Variance components quantitative trait locus association analysis was computed using SOLAR software, and a bivariate principal component analysis (PCA) assessed for genetic relationships between BMD and VC. Association was observed between several measures of BMD and BMP7 rs17404303 (thoracic spine QCT p = 0.03; lumbar spine QCT p = 0.02; hip DXA p = 0.06, dominant models). In addition, 6 of 16 BMP7 SNPs showed significant and opposing effects on the bivariate PCA for VC and BMD (two-sided exact test, p = 0.0143). Polymorphisms in BMP7 are associated with inverse relationships between bone mineralization and VC in the coronary, carotid, and abdominal aorta in a diabetes-enriched cohort of European Americans.</P>

Psychiatry

Freedman, Daniel X.,Stahl, Stephen M. MediMedia Korea 1993 JAMA-Korea Vol.8 No.12

Digoxin-Calcium Antagonist Interactions

Freedman, S.B. Medical Publications Korea 1986 Medical Progress Vol.8 No.7

Nam Joo-Hong 著, America's Commitment to South Korea, Cambridge University Press, 1986

Lawrence Freedman(서평자) 한국국제정치학회 1986 國際政治論叢 Vol.26 No.2