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Ferdinando N. Almeida,Mercedes Vazquez-Anon,Jeffery Escobar 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.7
Objective: The objective of this study was to evaluate increasing doses of a novel microbial phytase (Cibenza Phytaverse, Novus International, St. Charles, MO, USA) on standardized total tract digestibility (STTD) of P in canola meal (CM), corn, corn-derived distiller's dried grains with solubles (DDGS), rice bran (RB), sorghum, soybean meal (SBM), sunflower meal (SFM), and wheat. Methods: Two cohorts of 36 pigs each (initial body weight = 78.5±3.7 kg) were randomly assigned to 2 rooms, each housing 36 pigs, and then allotted to 6 diets with 6 replicates per diet in a randomized complete block design. Test ingredient was the only dietary source of P and diets contained 6 concentrations of phytase (0, 125, 250, 500, 1,000, or 2,000 phytase units [FTU]/kg) with 0.4% of TiO2 as a digestibility marker. Feeding schedule for each ingredient was 5 d acclimation, 5 d fecal collection, and 4 d washout. The STTD of P increased (linear or exponential p≤0.001) with the inclusion of phytase for all ingredients. Results: Basal STTD of P was 37.6% for CM, 37.6% for corn, 68.6% for DDGS, 10.3% for RB, 41.2% for sorghum, 36.7% for SBM, 26.2% for SFM, and 55.1% for wheat. The efficiency of this novel phytase to hydrolyze phytate is best described with a broken-line model for corn, an exponential model for CM, RB, SBM, SFM, and wheat, and a linear model for DDGS and sorghum. Based on best-fit model the phytase dose (FTU/kg) needed for highest STTD of P (%), respectively, was 735 for 64.3% in CM, 550 for 69.4% in corn, 160 for 55.5% in SBM, 1,219 for 57.8% in SFM, and 881 for 64.0% in wheat, whereas a maximum response was not obtained for sorghum, DDGS and RB within the evaluated phytase range of 0 to 2,000 FTU/kg. These differences in the phytase concentration needed to maximize the STTD of P clearly indicate that the enzyme does not have the same hydrolysis efficiency among the evaluated ingredients. Conclusion: Variations in enzyme efficacy to release P from phytate in various feedstuffs need to be taken into consideration when determining the matrix value for phytase in a mixed diet, which likely depends on the type and inclusion concentration of ingredients used in mixed diets for pigs. The use of a fixed P matrix value across different diet types for a given phytase concentration is discouraged as it may result in inaccurate diet formulation.
Matteo Cameli,Ferdinando Loiacono,Stefania Sparla,Marco Solari,Elisabetta Iardino,Giulia Elena Mandoli,Sonia Bernazzali,Massimo Maccherini,Sergio Mondillo 한국심초음파학회 2017 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.25 No.2
In patients with end-stage left ventricular (LV) heart failure who receive LV assist device (LVAD) implantation, right ventricular (RV) failure represents a possible critical complication that heavily affects morbidity and mortality. Several clinical, laboratory, hemodynamic, and echocardiographic variables have been found to be associated with RV failure occurrence after surgery. Different models and risk scores have been proposed, with poor results. No accordance has ever been reached about RV pre-operative evaluation, and time has come to introduce a standardized systematic protocol for LVAD suitability assessment according to RV function. We analyzed imaging parameters associated with LVAD implantation-related RV failure, in order to identify the minimum number for pre-operative reliable prediction of post-operative RV failure. A few echocardiographic parameters have been identified as the most reliable, or promising, and reproducible tools in this field: free-wall RV longitudinal strain, RV fractional area change, RV sphericity index, and RV ejection fraction with 3D-echocardiography. We propose the Systematic LVAD Implant Eligibility with Non-invasive Assessment protocol–the SIENA protocol–as a new and simple way of pre-operative evaluation of patients candidates to LVAD implantation.
A CFD approach to rubble mound breakwater design
Fabio Dentale,Ferdinando Reale,Angela Di Leo,Eugenio Pugliese Carratelli 대한조선학회 2018 International Journal of Naval Architecture and Oc Vol.10 No.5
The paper provides some developments of a numerical approach (“Numerical Calculation of Flow Within Armour Units”, FWAU) to the design of rubble mound breakwaters. The hydrodynamics of wave induced flow within the interstices of concrete blocks is simulated by making use of advanced, but well tested, CFD techniques to integrate RANS equations. While computationally very heavy, FWAU is gaining ground, due to its obvious advantages over the “porous media”, i.e. the possibility of accounting for the highly non stationary effects, the reduced need of ad hoc calibration of filtration parameters and also e in perspective e the evaluation of hydrodynamic forces on single blocks. FWAU however is a complex technique, and in order to turn it into a practical design tool, a number of difficulties have to be overcome. The paper presents recent results about this validation, as well as insight into fluid dynamical aspects.
A CFD approach to rubble mound breakwater design
Dentale, Fabio,Reale, Ferdinando,Di Leo, Angela,Carratelli, Eugenio Pugliese The Society of Naval Architects of Korea 2018 International Journal of Naval Architecture and Oc Vol.10 No.5
The paper provides some developments of a numerical approach ("Numerical Calculation of Flow Within Armour Units", FWAU) to the design of rubble mound breakwaters. The hydrodynamics of wave induced flow within the interstices of concrete blocks is simulated by making use of advanced, but well tested, CFD techniques to integrate RANS equations. While computationally very heavy, FWAU is gaining ground, due to its obvious advantages over the "porous media", i.e. the possibility of accounting for the highly non stationary effects, the reduced need of ad hoc calibration of filtration parameters and also - in perspective - the evaluation of hydrodynamic forces on single blocks. FWAU however is a complex technique, and in order to turn it into a practical design tool, a number of difficulties have to be overcome. The paper presents recent results about this validation, as well as insight into fluid dynamical aspects.
Francesco Grigioni,Antonio Russo,Ferdinando Pasquale,Elena Biagini,Francesco Barberini,Marinella Ferlito,Ornella Leone,Claudio Rapezzi 한국심초음파학회 2015 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.23 No.3
Knowledge of mitral regurgitation (MR) is essential for any care provider, and not only for those directly involved in the managementof cardiovascular diseases. This happens because MR is the most frequent valvular lesion in North America and the secondmost common form of valve disease requiring surgery in Europe. Furthermore, due to the ageing of the general population and thereduced mortality from acute cardiovascular events, the prevalence of MR is expected to increase further. Doppler echocardiographyis essential both for the diagnosis and the clinical management of MR. In the present article, we sought to provide a practicalstep-by-step approach to help either performing a Doppler echocardiography or interpreting its findings in light of contemporaryknowledge on organic (but not only) MR.
Experimental Characterisation of a Biologically Inspired 3D Steering Needle
Christopher Burrows,Riccardo Secoli,Ferdinando Rodriguez y Baena 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
Percutaneous intervention is a popular minimally invasive surgical technique, as it offers many potential advantages for the patient. Research efforts to date have focussed on improving the accuracy and applicability of this procedure through robotic control, in particular with the application of needle steering systems. Previously, we demonstrated two-dimensional (2D) steering within gelatine, with a prototype of a novel biologically inspired multi-segment needle, the STING. Then, a novel ‘programmable bevel’ concept, where the steering angle of the needle is a function of the offset between segments, was used to control the trajectory taken within the steering plane. This paper presents our first attempt to demonstrate controllable three-dimensional (3D) steering with a new four-segment prototype of the STING. We show that an approximately linear relationship exists between segment offset and curvature of the tip path for a single leading segment, as well as for two segments which are moved forward of the others by an equal amount. This characterisation is then demonstrated with 3D open loop experiments, which show that the established behaviour is applicable for controlled 3D steering along eight principal directions.