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Faiz Ur Rahman,You-Rim Kim,Su Jin Kim,Ho-Young Lee,Hyoung-Chin Kim,Ki-Hoan Nam 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7
Topoisomerases are crucial for solving DNA topological problems by making transient single-strand DNA or double-strand DNA nick. Topoisomerase IIIβ (Top3β) a member of topoisomerase family of enzymes and a major topoisomerase with dual-activity associated with neurodevelopment and mental dysfunction. The aim of this study was to examine the brain connectivities associated with behavioral alteration of Top3β mutant mice. We generated Top3β mutant (Top3β-/-) mice and determined behavioral characteristics of the mutant mice using an animal phenotype analysis platform which included open field test, grip strength, light-dark box, rota-rod, forced swim, Y-maze, fear conditioning and acoustic startle/prepulse inhibition analysis. Brain functional connectivity was also analyzed by PET/CT with [18F] fluorodeoxyglucose technique. Top3β-/- mice shows decreased anxiety/depression-like behaviors and circadian activity in several tests. Altered neuromuscular functions was also observed in Top3β deficient mice. Notably, the expression of Top3β was recognized clearly in the central nervous system, suggesting its role in controlling behavioral phenotype in mice. The functional brain imaging analysis revealed that several brain regions associated with neurodevelopmental and psychiatric disorders of mutant Top3β mice. The Top3β mutation induced significant changes in mouse behavior, which might be mediated by alterations in connectivity of its brain regions. These findings could provide a useful guide of brain disorders specific to Top3β mutation.
Faiz Ahmed,Mohammad Mahbubur Rahman,Sabuj Chandra Sutradhar,Nasrin Siraj Lopa,류태욱,윤수진,최인환,김재웅,Yongcheng Jin,김환기 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.78 No.-
This research demonstrates the synthesis of an imidazolium functionalized imide based electrolyte salt,lithium (fluorosulfonyl)((3-(1-methyl-1H-imidazol-3-ium-3-yl)propyl)sulfonyl)imide) bis(trifluorosulfonyl)imide (LiFSMIPTFSI) for the development of lithium-ion battery (LIB). The LiFSMIPTFSI electrolytewith a mix-solvent of ethylene carbonate (EC) and dimethyl sulfoxide (DMSO) (75:25 v/v) shows highelectrochemical oxidative stability (up to 5.3 V vs. Li/Li+), good Li+ conductivity (ca. 6.10 mS/cm at 30 C)and transference number (ca. 0.55), and low viscosity, which concurrently provide a specific capacity ofca. 141 mAhg 1 at 0.1 C with a full LIB structure of LiFePO4/LiFSMIPTFSI/graphite. The electrochemicalperformance of this electrolyte is enhancing additionally by adding conventional imide salts (lithium bis(fluoro-sulfonyl)imide (LiFSI) and lithium bis(trifluoromethylsulfonyl)imide (LiTFSI)) (20% each) asadditives with the specific capacity of ca. 160 and 150 mAhg 1, respectively, at 0.1 C. This is mainly due tothe additional enhancement of Li+ conductivity and transference number of the LiFSMIPTFSI electrolyteinduce by the additives. The LiFSMIPTFSI electrolyte with LiFSI additive based LIB shows the maximumcapacity retention of ca. 95.50% among the electrolytes after 500 charge-discharge cycles, along with highcoulombic efficiency (98.50%).
Faiz Majeed,Dania Batool,Jonghoon Kim 전력전자학회 2021 전력전자학술대회 논문집 Vol.2021 No.11
The existing energy resources offer a huge amount of potential to threaten the survival of planet Earth. To overcome such disasters as climate change, solar energy offers a solution. In this regard, many types of research have been done to produce cost-effective and efficient solar energy. There are lot of factors on which efficiency of solar panel depends, finding the maximum power point angle is one of those factors and the presented work is also related to it. This paper proposes a system that is intelligent enough to find the angle of the solar panel where maximum energy is produced. The maximum energy producing angle is measured on only one solar panel, the information of the maximum energy producing angle is shared with the whole system and all the solar panels are moved accordingly. This paper proposes to use the proportional integral differential controller to move the solar panels to maximize energy producing angle. This design helps in saving computational load from all solar panels and in the production of maximum energy.
Robust H∞ State Feedback Control of NCSs with Poisson Noise and Successive Packet Dropouts
Faiz Rasool,Sing Kiong Nguang 제어·로봇·시스템학회 2015 International Journal of Control, Automation, and Vol.13 No.1
This paper examines various constraints of networked control systems (NCSs) such as network- induced random delays, successive packet dropouts and Poisson noise. Time delays are represented as modes of Markov chain and successive packet dropouts are modeled using Poisson probability distribution. For each delay-mode, a separate Poisson distribution is used with the help of an indicator function. Poisson noise is incorporated in the design to cater sudden network link failures and power shutdowns. After modeling these constraints, a stability criterion is proposed by using Lyapunov- Krasovskii functional. On the basis of the stability criteria, sufficient conditions for the existence of a robust H∞ state feedback controller are given in terms of bilinear matrix inequalities (BMIs). Later, BMIs are converted into quasi-convex linear matrix inequalities (LMIs) and are solved by using a cone complementarity linearizing algorithm. The effectiveness of the proposed scheme is elaborated with the help of two simulation examples. Moreover, the effects of successive packet dropouts and Poisson noise on H∞ performance are analyzed.
Faiz Hafeez Azhar,Zawati Harun,Siti Salwa Alias,Muhamad Zaini Yunos,Siti Aida Ibrahim,Tijjani Abdullahi,Azlinnorazia Ahmad,Mohd Hafiz Dzarfan Othman 한국고분자학회 2020 Macromolecular Research Vol.28 No.6
The photocatalytic polymer mixed matrix membrane (MMM) has been widely used for the separation and purification process. The objective of this study is to investigate the effect of structural TiO2 (synthetic TiO2 (ST), flower-like TiO2-100 (FLT-100), and flower-like TiO2-600 (FLT-600)) based on the total surface area for the efficient self-cleaning antifouling property. The asymmetric MMMs were fabricated using the phase inversion process with a different type of structural TiO2 as additive. As a result, the addition of synthesized FLT, especially FLT-100, has influenced the hydrophilicity and surface roughness of the MMM. From the powder analysis, FLT-100 exhibits the highest total surface area with 37.25 m2/g and strongly affects the self-cleaning antifouling performance of the MMM. This membrane produced the highest self-cleaning efficiency (68.8%) compared to FLT-600 (58%) and ST (39.8%) after UV exposure, thus, indicates in a better self-cleaning antifouling property that offers the potential to be considered for commercialization in reducing the maintenance cost by using both physical and chemical cleaning method that becomes a problem in membrane technologies.
Behaviour of Carbon and Basalt Fibres Reinforced Fly Ash Geopolymer at Elevated Temperatures
Faiz Shaikh,Sharany Haque 한국콘크리트학회 2018 International Journal of Concrete Structures and M Vol.12 No.4
This paper presents the behaviour of potassium activators synthesized fly ash geopolymer containing carbon and basalt fibre at ambient and elevated temperature. Six series of fly ash based geopolymer were cast where carbon and basalt fibre were added as 0.5, 1 and 1.5% by weight of fly ash. One extra control series without any fibre was also cast. Each series of samples were tested at ambient temperature and also heated at 200, 400, 600 and 800℃ and thus a total of 35 series of samples were tested in this study. The result shows that the geopolymer containing 1 wt% basalt and 1 wt% carbon fibre exhibited better compressive strength, lower volumetric shrinkage and mass loss than other fibre contents. Among two fibres composites, the carbon fibre geopolymer exhibited better performance than its basalt fibre counterpart regardless of temperature. The microstructure of carbon fibre reinforced geopolymer composite is more compact containing fewer pores/voids than its basalt based counterpart at elevated temperatures. The results also support the fact that carbon fibre is better than basalt fibre at elevated temperature and showed better bonding with geopolymer at elevated temperature.