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      • Polyethylene glycol 용액(Colyte^(R))을 복용한 후 발생한 Boerhaave 증후군 1예

        이관행,기승석,김인숙,김민정,박인호,장세중,하지수,김응수 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

        Spontaneous esophageal rupture (Boerhaave's syndrome) is a rare case that require early diagnosis and treatment because of its high mortality. The oral administration of osmotically balanced polyethylene-glycol-based electrolyte preparation is a commonly prescribed preparation for cleansing in patients undergoing colonoscopy. Nausea, vomiting and abdominal pain are frequently seen, but serious adverse reactions are rare. Esophageal rupture secondary to severe vomiting, which occurred during colonoscopy preparation using polyethylene gIycoI(PEG) electrolyte solution is extremely rare and only few cases have been published in the literature. We report a case of spontaneous esophageal rupture after routine administration of the PEG before colonoscopy. 대장 정결을목적으로 PEG 사용 후 아주 드물게 발생하는 Boerhaave 증후군 1예를 경험하였기에 보고하는 바이다.

      • ENHANCED HUMUS FORMATION IN A SUBSTRATE- CONTROLLED COMPOSTING REACTOR

        황은주,김준수,전관수 대구대학교 환경기술연구소 2004 미래환경기술 Vol.1 No.1

        A substrate-amended fed-batch composting of food waste was investigated and its effect on humus formation and cellulose decomposition were studied. Various substrates were added to the reactor in fed-batch mode while no additional feed was introduced into the other reactor for comparison. Active composting was prolonged by the amendment of substrate. Cellulose composition changed from initial value of 33.4% to 32.6% in conventional batch composting. Cellulose decreased to 30.2% in the substrate-amended, fed-batch composting. It decreased further to 24.2% when the amount of substrate amendment increased in the fed-batch composting. Humus formation was enhanced in the substrate-amended composting. Humic substances were produced more in the fed-batch composting (7.47% and 8.76%) as compared to conventional batch composting (7.12%). About 5% to 23% increase in humic substance was achieved in the fed-batch composting. It was confirmed that the substrate-amended, fed-batch composting improved the degradation of cellulose and the formation of humus.

      • Landsat TM data로부터 수질인자 추출을 위한 상대적 대기 보정 방법

        김응남,양인태,최윤관 江原大學校 産業技術硏究所 1998 産業技術硏究 Vol.18 No.-

        Recently there are a lot of studies to use a satelite image data in order to investigate a simultaneous change of a wide range area as a lake . However, many cases of a water quality research occur as problem when we try to extracty the water quality factros from the stelite image data, because of the atmosphere scattering exert as bad influence on a result of analysis. In this study, and attempt was made to select the relative atmospheric correction method for the water quality factors extraction from the satelite image data. And also, the time -series analysis of the water quality factors extraction from the satelite image data. And also, the time-series analysis of the water quality factors was performed by using the multi-temporal image data.

      • KCI등재후보

        아조(Azo)화합물 열분해특성

        김관응 한국산업안전학회 2002 한국안전학회지 Vol.17 No.2

        This study was investigated the thermal decomposition characteristics of azo type sponge blowing agent azodicarbonamide(ADCA) using differential scanning calorimeter(DSC). The experimental results showed that the exothermic onset temperatures(T。) for ADCA were about 201~206℃ and evolution heats(Q) were about 144~150㎈/g. The exothermic onset temperatures(T。), exothermic maximum temperature(T_m) and exothermic final temperature(T_r) were decreased by decreasing particle size of ADCA and evolution heats(Q) were increased with it. T。 and Q for 6.1~7.2?? ADCA were increased by increasing heating rate at constant sample weight and activation energy was about 37.29㎉/㏖. A positive gas pressure was employed in the elucidation of the decomposition behavior of ADCA because it sublimes during linear heating at atmospheric pressure. T。 and Q of ADCA tended to increase with a pressure in air or nitrogen. In the case of azo dye, experimental results showed that T。 were about 280~420℃ and Q were about 2~3㎈/g.

      • 가용성 폴리피롤의 합성 및 특성분석

        장관식,박종주,오응주,서정선 명지대학교 자연과학연구소 1996 자연과학논문집 Vol.13 No.-

        Dodecylbenzenesulfonate와 naphthalenesulfonic acid를 음이온도판트로 사용하고 산화제로 (NH₄)₂S₂O??을 사용하여 상온에서 가용성 폴리피롤을 화학적으로 합성하였다. 제조된 폴리피롤을 여러가지 유기용매(m-cresol, 콜로포름, NMP, DMSO등)에 녹여 free standing film을 제조하였다. 폴리피롤 free standing film은 실온에서 10??∼6S/cm의 전기전도도와 15∼20MPa의 인장강도를 나타내었다. 클로로포름, m-cresol용매에서 제조한 폴리피롤 용액은 UV-Vis./NIR 스펙트라의 측정결과 근적외선영역에서의 free carrier tail 현상을 보여주었고, 폴리피롤 free standing film은 매끈한 표면을 형성하였으며 TGA 측정결과 450℃ 부근에서의 고분자의 분해에 기인되는 중량감소를 나타내었다. 제조된 폴리피롤은 PMMA 등의 고분자와의 우수한 혼합특성을 나타내었다. Doped polypyrroles with anionic dopants, dodecylbenzenesulfonate and naphthalenesulfonic acid which are soluble in various organic solvents are chemically synthesized by oxidative polymerization of pyrrole with ammonium persulfate as a oxidant. Free standing films prepared from several solvents(m-cresol, chloroform, NMP, DMSO etc.) show electrical conductivities of 10??∼6S/cm and tensile strength of 15∼20MPa. Polypyrrole solution prepared from m-cresol and chloroform shows free carrier tail in the near IR region which is attributed to the delocalization of charge carriers and free standing films prepared from these solvents shows smooth surface morphology and the weight loss due to the degradation of polymer chain around 450oC. Polypyrrole solutions prepared from m-cresol and chloroform show high degree of miscibility with PMMA and good film forming property.

      • SCOPUSSCIEKCI등재

        폐쇄성 수면 무호흡증 환자에 있어서 하악 재위치 장치 장착과 체위에 따른 상기도 구조와 근활성도의 변화에 관한 EMG 및 두부방사선학적 연구

        박영철,배응권,이정권,이종석,김태관 대한치과교정학회 1998 대한치과교정학회지 Vol.28 No.4

        폐쇄성 수면 무호흡증(obstructive sleep apnea, 이하 OSA로 표시)은 수면 도중 계속 반복 되어 일어나는 상기도 폐쇄로 인하여 무호흡증을 나타내는 장애(disorder)이다. 근래의 연구에 의하면 상기도 구조의 해부학적 요인뿐 아니라 생리적 요인도 무호흡 발생에 기여한다고 하였으며 또한 이설근이 상기도 유지에 중요한 역할을 한다고 하였다. OSA의 치료를 위해 다양한 술식이 시행되었으며 하악 재위치 장치를 통한 치료 역시 양호한 결과를 나타낸다고 하였다. 그러나 하악 재위치 장치 장착에 따른 구조적 생리적 작용기전에 대한 연구는 미비한 상태이다. 이에 본 저자는 연세대학교 치과대학병원 교정과에 내원한 OSA 환자 26명(남 17명, 여 9명)과 일반 정상 성인 20명(남 10명 여 10명)을 대상으로 앙와위에서 장치 장착 전후의 두부방사선사진을 채득하여 장치에 따른 상기도의 구조 변화를 연구하고 두군 사이의 장치 장착에 따른 효과를 비교하였으며, 또한 OSA 환자 14명(남자 10명 여 4명)을 대상으로 체위 변화와 장치장착에 따른 이설근 근전도 변화를 연구하여 다음과 같은 결론을 얻었다. 1. 상기도 구조에 대한 두부계측학적 측정치 중 연구개의 길이, 연구개 최대 두께와 SPAS, MAS, VAL, H-H1. MP-H에서 정상군과 OSA군 사이의 통계적 유의차를 보였으며, IAS와 EAS는 두 군간에 통계적 유의차를 보이지 않았다. 2. 정상군과 OSA군 모두에서 장치 장착에 따라 후두개가 전방 이동하면서 후두개 수준(epiglottis level)의 기도 폭경은 증가하였고 연구개의 최대 두께가 변하였으며 설골은 전방 이동하였으나 두 군 모두 IAS에서는 다양한 반응을 나타내었다. 장치 장착에 따른 상기도 구조에 대한 효과는 두 군 사이에 서로 차이을 나타내었다. 3. 체위 변화에 따라 앙와위에서 이설근 근전도가 증가하는 경향을 나타내었으나 통계적 유의차는 없었으며, 직립위와 앙와위 모두에서 하악 재위치 장치 장착시에 통계적으로 유의하게 이설근 근전도가 증가하였다. 하악 재위치 장치는 상기도의 해부학적 구조뿐 아니라 상기도 영향을 미치는 것으로 생각되며 장치에 대한 반응은 정상군과 OSA군 사이에 차이를 나타내었고, 두 군은 상기도 생리에 있어서도 서로 다르다고 사료된다. Obstructive sleep apnea (OSA)is a disorder characterized by repetitive episode of upper airway collapse during sleep. Recent studies showed that not only the anatomic factors but the physiologic factors of the upper airway also have effects on the occurrence of apnea and that the genioglossus muscle also plays in important role in the maintenance of the upper airway. A variety of therapies were performed to treat OSA, and among them the use of mandibular repositioning appliances showed reasonable results. But there is still a lack of research on the structural and physiological mechanism upon the use of mandibular repositioning appliances. The author selected 26(male 17, female 9) OSA patients that came to the Yonsei University Dental Hospital, Department of Orthodontics, and 20 normal adults (male 10, female 10) and took cephalometric radiographs of them in a supine position before and after the palcement of the mandibular repositioning appliance to see the structural changes of the upper airway and compare the therapeutic effects between the two groups. We also studied the waking genioglossus muscle activity in OSA patients and investigated the difference in the electromyogram of the genioglosssus muscle upon the change in body posture and the use of mandibular repositioning appliance. Following results were obtained. 1. Among the cephalometric measurements of the upper airway structure, the length of the soft palate, maximum thickness of the soft palate and SPAS, MAS, VAL, H-HI, MP-H showed statistically significant differences between the normal and OSA groups, but the IAS and EAS showed no statistically significant differences between the two groups. 2. In both the normal and OSA groups, as the epiglottis moved forward on wearing the mandibular repositioning appliance, the epiglottis level of the upper airway increased and the maximum thickness of the soft palate changed and the hyoid bone also moved forward, but the IAS in both groups showed various results and the effect of the mandibular repositioning appliance on the structure of the upper airway was different in the two groups. 3. Upon changing the position, the electromyogram of the genioglossus muscle showed a increasing tendency but there was no statistically significant differences, and when the mandibular repositioning appliance were worn there was a statistically significant increase in the electromyogram of the genioglossus muscle in both the upright and supine positions. The mandibular repositioning appliances not only have an effect on the anatomical structure of the upper airway but also on the physiology of the upper airway. There are different responses to the use of mandibular repositioning appliance between the normal and OSA groups therefore it could be considered to have the different physiology of the upper airway between the two groups.

      • 기억에 미치는 대뇌변연계의 기능적 역할 : 에탄올 급성 투여 흰쥐의 행동 및 신경화학적 변화 Behavioral and Neurochemical Alterations Following Acute Administration of Ethanol in Rats

        이순철,유관희,김응배 충남대학교 약학대학 의약품개발연구소 1995 藥學論文集 Vol.11 No.-

        Behavioral and neurochemical effects of ethanol were assessed in rats after acute administration. Ethanol, 1-5g/㎏, inhibited the memory and rotarod performance, but significantly increased the spontaneous locomotor activity. Ethanol, 1-5g/㎏, did not affect the striatal dopaminergic neuronal activity and cortical noradrenergic neuronal activity. Ethanol, 1g/㎏, decreased the contents of DA(46.7%), DOPAC(66.7%) and HVA(79.2%) in frontal cortex, but increased the contents of DA(125%), DOPAC(116.7%) and HVA(l40%) in hippocampus. Ethanol, 2-5g/㎏, significantly increased the dopaminergic neuronal activity in frontal cortex, while it remarkably decreased the monoaminergic neuronal activity in hippocampus. These results suggest that the activity of cotical dopaminergic neuron play an important role in modulation of the motot activity induced by low does of ethanol, and that the activity of cotical and hippocampal catecholaminergic neurons could be responsible for the control of memory induced by higher does of ethanol.

      • KCI등재

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