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      • 원발성 연수 출혈증 1예

        하현욱,한정호,이정석,송은향,김우정,김두응,최진영 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

        Pure primary medullary hemorrhage is a rare condition, which is characterized by ipsilateral hypoglossal nerve palsy and contralateral hemiparesis. The hemorrhage usually extended to medial and ventral medulla, these two characteristic signs distinguished from the classical presentation of Wallenberg's lateral medullary syndrome. A 53-years-old man was admitted with sudden onset left sides weakness and vertigo. Neurologic examination showed dysarthria, mild dysphagia, Horner syndrome of right side, spontaneous horizontal jerking nystagmus to left side and right deviation of tongue at protrusion. Pain and temperature sensation of left trunk, left extremity and right face were decreased. Brain CT scan and brain MRI revealed focal hemorrhage in the right medulla. We report a case of pure primary medullary hemorrhage with undetermined etiology.

      • 효모에 의한 알콜발효에서 Inoculum의 농도, pH 및 물의 종류의 영향

        김승욱,김은영 수원대학교 산업기술연구소 1991 산업기술연구소논문집 Vol.6 No.-

        The effect of inoculum level, pH and various water on ethanol fermentation by Saccharomyces W1 was investigated. One loop, 5%(v/v), 10%(v/v), 15%(v/v) and 20% (v/v) of inoculum were tested to find a proper inoculum level. It was found to be one loopful of yeast cell. For the pH range between 3.0 and 7.5, the optimum for ethanol production was found to be pH 5.5. The effect of various water on ethanol production was studied. Ethanol concentrations produced by using tap water of Seoul and Suwon, and ground water of Suwon University were fairly similar. However, in the case of distilled water, ethanol concentrations produced were slightly lower than others tested.

      • 수포독성 처치용 외용제 제제설계를 위한 약물의 검색

        김동욱,박은석,지상철 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

        Abstract-The effects of various drugs on the alleviation of the symptoms of chemical burns were evaluated in mice to formulate topical antiblister preparations. After a chemical burn was induced on the mouse dorsal skin with 2-chloroethylethyl sulfide, the drug was applied on the disease site. The effectiveness of the drug was evaluated by determining blister size, necrosis score of skin and appearance of the chemical burns induced. It showed that steroids and aminoglycoside antibiotics had a tendency to protect skin cell, and antihistamines decreased the size of chemical burns. While oleaginous base resulted in deleterious effect, hydrophilic base didn't show a significant difference on the alleviation of the chemical burn symptoms compared to the control.

      • 분만시 지속적 또는 간헐적 투여에 의한 경막외 제통의 비교

        박욱,이은찬,배상철,강규식,곽수달 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        Background : Continuous epidural infusion of the mixed solution of local anesthetic (bupivacaine) and lipid-soluble opioid (fentanyl) has known as a more useful method than intermittent epidural injection for relief of pain during labor. The purpose of this study was to compare a clinical usefulness between continuous infusion and intermittent injection with epidural analgesia during labor. Methods: One hundred healthy parturients were divided into two groups as follows: Continuous epidural group (C-group); 50 parturients received epidural analgesia continuously with 0.167% bupivacaine and 0.000167% fentanyl in the speed of 10 ml h-1 at cervical dilatation (3-5 cm) and then injected 0.25% bupivacaine 5 ml additionally at complaints of severe labor pain. Intermittent epidural group (I-group); 50 parturients received inermittently 0.167% bupivacaine and 0.00083% fentanyl in the initial dose of 12 ml at cervical dilatation (3-5 cm) and then additionally used the same dose at severe labor pain. Result: There were no statistically significant differences in the clinical states of maternoneonate, pain free score, degree of motor block, mode of delivery, cause of Cesarean section, neonatal Apgar score and incidence of side effects between groups(Table 1.2.3.7.8). The total dose of bupivacaine and fentanyl, the duration of lst and 2nd delivery stages and the frequency of top up injection for incomplete relief of pain during labor appeared significant differences in statistics between groups (Table 4.5.6). Conclusion: It was similar to the effectiveness of maternal epidural analgesia during labor between groups by means of continuous or intermittent injection.

      • 심실전도장애환자에서 위상각 분석의 의의

        전은석,곽병수,이강욱,박종훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        It is known that the normal His-Purkinje system provides for nearly synchronous activation of the right and left ventricles. When this His-Purkinje conduction is abnormal, the resulting sequence of the both ventricular contraction should be changed. These abnormal mechanical consequences resulting from abnormal conduction system have been difficult to demonstrate because these are very rapid and complex. We evaluate the phase angle analysis using radionuclide gated blood pool scan(GBP) as a quantitative method which can determine the asynchronous contraction of left ventricule in patients with complete left bundle branch block(C-LBBB, 20 cases) and complete right bundle branch block(C-RBBB, 15 cases). The results as follows : 1) The ejection fractions, peak ejection rates, in GBP were significantly decraesed in patients with C-LBBB compared with controls(10 cases, 70± 4.2 vs 44± 13.9%, 3.51± 0.62 vs 2.48± 0.98, p<0.05 by t-test respectively). The peak filling rates were also decreased in patients with C-LBBB(3.38± 0.92 vs 1.76± 0.71, 1A.05). 2) In the phase angle analysis, the standard deviations and the width of half maximum of phase angle were significantly increased in patients with C-LBBB(8.6± 1.8 vs 20.6± 18.1, 16.0± 3.9 vs 22.5± 9.2, p<0.05 by t-test respectively). And the ranges of phase angle were also increased in C-LBBB(51.3± 5.4 vs 95.7± 31.7, p<0.05). 3) But there were no significant differences in GBP and phase angle analysis between patients with C-RBBB and controls. As the results above, it can be concluded that the phase angle analysis can provide an accurate noninvasive method to detect the asynchronous contraction in patients with abnormal intraventricular electrical activation.

      • 일개 지역에서 b형 헤모필루스 인플루엔자 뇌수막염 예방접종을 하게 되는 경로

        사은주,이동욱,성낙진,박기흠 東國大學校醫學硏究所 2007 東國醫學 Vol.14 No.1

        We aimed to investigate people's recognition of immunization for Haemophilus influenza type b(Hib) meningitis, their knowledge of the vaccination as an option, the resources for parents, and the effective measures of promoting vaccination rate. From April 20th to May lOth, 2006, we assessed children who visited either a public health center or an university hospital for scheduled vaccination. We analyzed their general characteristics, vaccination rate for Hib, and resources for parents by using the self-written questionnaires. Furhermore, ingestigator rechecked the questionnaire by one-on-one interview. Among the collected self-written questionnaires, the adequately answered cases for the study were conducted by 95 parents from public health center group and 95 from university medical center group. 77 children (81.1%) received vaccination at public health center and 79 children (81.4%) at university medical center. 133 parents (69.3%) had the knowledge of Hib vaccination and as an optional injection, 52 parents (27.1%) knew about the vaccination but without the immunization awareness as an option, and 7 parents (3.6%) did not even know the Hib vaccination itself. Out of 156 children who underwent the vaccination, most parents of 87 (56%) obtained the resources on Hib vaccination from their baby check booklets. Despite the fact that the Hib immunization is an optional vaccine, almost all of people still seek for the Hib vaccination. The good use of baby check booklets would be a significant tool for immunization awareness. 5세이하 소아들의 보호자들이 b형 헤모필루스 인플루엔자 뇌수막염(이하 Hib) 예방접종에 관해 알고 있는지, 이 접종이 선별접종임을 알고 있는지, 또 어떤 경로로 접종하고 있는지를 조사하여 접종률을 올릴 수 있는 방안을 모색해 보고자 이 조사를 시행하였다. 이 연구는 2006년 4월 20일부터 5월 10일까지 서로 인접한 일개시의 보건소 및 대학병원에서 기본접종을 위해 내원한 15개월 이상의 소아들을 대상으로 조사하였다. 미리 구성한 자기기입식 설문지를 이용하여 일반적 특성, Hib 예방접종의 접종률 및 접종경로 등을 조사하였다. 이후에 조사자가 설문지 내용을 1:1 면담으로 다시 확인하였다. 그 결과 Hib 예방 접종을 시행한 경우는 보건소에서 조사한 95명 중 77명(81.1%),대학병원에서 조사한 97명 중 79명(81.4%)이었다. Hib 예방접종이 선별접종임을 아는 경우는 133명(69.3%)이었으며 Hib 예방접종은 알고 있지만 선별접종임을 모르는 경우가 52명(27.1%), Hib 예방접종 자체를 모르는 경우는 7명(3.6%)이었다. Hib 예방접종을 시행한 156명 중 Hib 예방접종을 알게 된 경위가 아기수첩을 보고 알게 된 사람이 87명(56%)으로 가장 많았다. Hib 예방접종이 선별접종임에도 불구하고 대다수에서 접종을 하고 있으며 아기수첩의 적절한 활용이 예방접종률을 높이는데 중요한 수단이 될 수 있다.

      • 6차와 개편된 7차 교육과정 중학교 과학 교과서 생물영역에 대한 비교 분석

        장은영,조현욱,김종홍 順天大學校 師範大學 附屬 科學敎育硏究所 2002 科學과 敎育 Vol.10 No.-

        The purpose of this study is to compare and analyze the biology area of the 6th and the revised 7th curriculum in the middle school The 6th curriculum emphasized the research activities. It also gave emphasis on the biological materials in our surroundings, field studies, open questions and various applications and the participation in scientific events, while the new curriculum points on the ability to group either between classes or within classes. In―depth and supplementary differentiated curriculum in the 7th curriculum makes "level―based differentiated curriculum" possible and stresses the synthetic research activities, which deal with fundamental notions and the research processes. Looking into the degree of emphasis for each scientific area, the new textbooks have 12 chapters, but the old textbooks have 4 chapters. The allotment of each scientific area is almost same in the new textbooks, through matter (22.7%) takes up less pages than other areas. In the old textbooks, the number of pages allotted for biological subjects is 28.4% and takes up more pages than other areas. The content dealing with biological area comprises 67.5 pages of the new textbooks and 77 pages of the old textbook. The items analyzing constituents for the research activities appear in the new textbooks. These constituents are planning observing and assuming, investigating, reading and building ideas. The common experiments in both textbooks are 22 in the new textbooks, and 11 in the old textbooks.

      • 효모의 고정화를 위한 Alginate Fiber의 개발

        金承昱,金銀英 수원대학교 산업기술연구소 1993 산업기술연구소논문집 Vol.8 No.-

        Stabilities of Ca-alginate fiber and ACP(Alginate+Celite R-634+Pectin) gel fiber containing various concentrations of alginate were tested. The results showed that the stability of ACP gel fiber containing 5% alginate(5% ACP gel fiber) was better than that of other fibers tested, considering the degree of release of yeast from gel fiber. SEM observation proved the above results, and ethanol concentration obtained by 5% ACP gel fiber was higher than that of others.

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