Multi-mode Kernel Weight-based Object Tracking

Eun-Sub Kim(김은섭),Yong-Goo Kim(김용구),Yoo-Joo Choi(최유주) 한국컴퓨터그래픽스학회 2015 컴퓨터그래픽스학회논문지 Vol.21 No.4

최근, 감시시스템, 게임, 영화 등 다양한 분야에서 영상을 이용한 실시간 객체 추적의 필요성이 높아짐에 따라, 커널기반 mean-shift 추적 기법에 대한 관심이 높아지고 있다. 커널 기반 mean-shift 객체 추적에 있어서 주요한 몇 가지 문제점들 중, 첫 번째로 추적 목표 객체에 대한 부분 가림 혹은 전체 가림 상황에서의 객체 추적의 문제를 들 수 있다. 본 논문에서는 멀티모드 지역적 커널 가중치를 적용함으로써 부분 가림 상황에서도 안정적으로 객체를 추적할 수 있는 실시간 mean-shift 추적 기법을 제안한다. 제안기법에서는 단일 커널을 사용하는 대신 여러 개의 서브 커널들로 구성된 커널을 사용하고, 각 서브 커널의 위치에 따른 지역적 커널 가중치를 적용한다. 기존의 멀티모드 커널 기반의 방법과 비교한 실험을 통하여 본 제안 방법이 보다 안정적으로 객체를 추적할 수 있음을 보였다. As the needs of real-time visual object tracking are increasing in various kinds of application fields such as surveillance, entertainment, etc., kernel-based mean-shift tracking has received more interests. One of major issues in kernel-based mean-shift tracking is to be robust under partial or full occlusion status. This paper presents a real-time mean-shift tracking which is robust in partial occlusion by applying multi-mode local kernel weight. In the proposed method, a kernel is divided into multiple sub-kernels and each sub-kernel has a kernel weight to be determined according to the location of the sub-kernel. The experimental results show that the proposed method is more stable than the previous methods with multi-mode kernels in partial occlusion circumstance.

Sodium butyrate has context-dependent actions on dipeptidyl peptidase-4 and other metabolic parameters

Lee, Eun-Sol,Lee, Dong-Sung,Pandeya, Prakash Raj,Kim, Youn-Chul,Kang, Dae-Gil,Lee, Ho-Sub,Oh, Byung-Chul,Lee, Dae Ho The Korean Society of Pharmacology 2017 The Korean Journal of Physiology & Pharmacology Vol.21 No.5

Sodium butyrate (SB) has various metabolic actions. However, its effect on dipeptidyl peptidase 4 (DPP-4) needs to be studied further. We aimed to evaluate the metabolic actions of SB, considering its physiologically relevant concentration. We evaluated the effect of SB on regulation of DPP-4 and its other metabolic actions, both in vitro (HepG2 cells and mouse mesangial cells) and in vivo (high fat diet [HFD]-induced obese mice). Ten-week HFD-induced obese C57BL/6J mice were subjected to SB treatment by adding SB to HFD which was maintained for an additional 16 weeks. In HepG2 cells, SB suppressed DPP-4 activity and expression at sub-molar concentrations, whereas it increased DPP-4 activity at a concentration of $1,000{\mu}M$. In HFD-induced obese mice, SB decreased blood glucose, serum levels of insulin and $IL-1{\beta}$, and DPP-4 activity, and suppressed the increase in body weight. On the contrary, various tissues including liver, kidney, and peripheral blood cells showed variable responses of DPP-4 to SB. Especially in the kidney, although DPP-4 activity was decreased by SB in HFD-induced obese mice, it caused an increase in mRNA expression of $TNF-{\alpha}$, IL-6, and $IL-1{\beta}$. The pro-inflammatory actions of SB in the kidney of HFD-induced obese mice were recapitulated by cultured mesangial cell experiments, in which SB stimulated the secretion of several cytokines from cells. Our results showed that SB has differential actions according to its treatment dose and the type of cells and tissues. Thus, further studies are required to evaluate its therapeutic relevance in metabolic diseases including diabetes and obesity.

Acute and Sub-chronic Oral Toxicity Study of Ammonium Persulfate in Spraque-Dawley Rats

Yong Soon Kim,Min Won Baek,Jae Hyuck Sung,Hyun Youl Ryu,Jin Sik Kim,Hyun Sun Cho,Byung Gil Choi,Min Sub Song,Moon Yong Song,Eun Ju Baik,Young Kuk Choi,Jong Kyu Kim,Il Je Yu,Kyung Seuk Song 한국독성학회 2009 Toxicological Research Vol.25 No.3

The toxicity test of ammonium persulfate was conducted to ensure of its potential toxic effects according to the single-dose acute oral toxicity study (OECD Guideline 423) and 90-day repeated dose sub-chronic oral toxicity study guideline (OECD Guideline 408) for establishing national chemical management system, and matching in the Globally Harmonized Classification System (GHS) category. In acute oral toxicity study, pasty stool, perineal contamination and temporary body weight decrease were observed after dosing 1st and 2nd challenge (300 ㎎/㎏ body weight). All test animals were dead within 6 hours after dosing at 3rd challenge (2000 ㎎/㎏ body weight). Therefore, the GHS class of test substance is considered class 4. In sub-chronic toxicity study, body weight changes, food consumptions, hematological, biochemical and pathological examination did not show any noticeable and significant differences between the administered (5, 20, 80 ㎎/㎏ body weight) and control (vehicle only) group animals. Based on these results, the no observed adverse effect level (NOAEL) is considered above 80 mg/kg body weight.

Acute and Sub-chronic Oral Toxicity Study of Ammonium Persulfate in Spraque-Dawley Rats

Kim, Yong-Soon,Baek, Min-Won,Sung, Jae-Hyuck,Ryu, Hyun-Youl,Kim, Jin-Sik,Cho, Hyun-Sun,Choi, Byung-Gil,Song, Min-Sub,Song, Moon-Yong,Baik, Eun-Ju,Choi, Young-Kuk,Kim, Jong-Kyu,Yu, Il-Je,Song, Kyung-Se Korean Society of ToxicologyKorea Environmental Mu 2009 Toxicological Research Vol.26 No.3

The toxicity test of ammonium persulfate was conducted to ensure of its potential toxic effects according to the single-dose acute oral toxicity study (OECD Guideline 423) and 90-day repeated dose sub-chronic oral toxicity study guideline (OECD Guideline 408) for establishing national chemical management system, and matching in the Globally Harmonized Classification System (GHS) category. In acute oral toxicity study, pasty stool, perineal contamination and temporary body weight decrease were observed after dosing 1st and 2nd challenge (300 mg/kg body weight). All test animals were dead within 6 hours after dosing at 3rd challenge (2000 mg/kg body weight). Therefore, the GHS class of test substance is considered class 4. In sub-chronic toxicity study, body weight changes, food consumptions, hematological, biochemical and pathological examination did not show any noticeable and significant differences between the administered (5, 20, 80 mg/kg body weight) and control (vehicle only) group animals. Based on these results, the no observed adverse effect level (NOAEL) is considered above 80 mg/kg body weight.

Anti-Cancer Effect of Ginsenoside F₂ against Glioblastoma Multiforme in Xenograft Model in SD Rats

Shin, Ji-Yon,Lee, Jung-Min,Shin, Heon-Sub,Park, Sang-Yong,Yang, Jung-Eun,KimCho, So-Mi,Yi, Tae-Hoo The Korean Society of Ginseng 2012 Journal of Ginseng Research Vol.36 No.1

The glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. Despite combination treatments of radiation and chemotherapy, the survival periods are very short. Therefore, this study was conducted to assess the potential of ginsenoside $F_2$ (F2) to treat GBM. In in vitro experiments with glioblastoma cells U373MG, F2 showed the cytotoxic effect with $IC_{50}$ of 50 ${\mu}g/mL$ through apoptosis, confirmed by DNA condensation and fragmentation. The cell population of cell cycle sub-G1 as indicative of apoptosis was also increased. In xenograft model in SD rats, F2 at dosage of 35 mg/kg weight was intravenously injected every two days. This reduced the tumor growth in magnetic resonance imaging images. The immunohistochemistry revealed that the anticancer activity might be mediated through inhibition of proliferation judged by Ki67 and apoptosis induced by activation of caspase-3 and -8. And the lowered expression of CD31 showed the reduction in blood vessel densities. The expression of matrix metalloproteinase-9 for invasion of cancer was also inhibited. The cell populations with cancer stem cell markers of CD133 and nestin were reduced. The results of this study suggested that F2 could be a new potential chemotherapeutic drug for GBM treatment by inhibiting the growth and invasion of cancer.

Characterization of OsJAC1 which is responding to different types of ionizing radiation

In jung Jung,Jung Eun Hwang,Sung Min Han,Hong-Il Choi,Soon-Jae Kwon,Jin-Baek Kim,Si-Yong Kang,Dong Sub Kim 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

Ionizing radiation affects gene expression from plant genomes. To monitor the genome-wide transcriptional changes induced by three types of ionizing radiation, we used the rice RNA sequencing to identify genes that are up- or down-regulated by gamma rays (GAs), proton (PRs) and ion beams (IBs). The Oryza sativa jacalin-like lectin domain containing proteins (OsJAC1) gene was highly induced by GAs, PRs and IBs. OsJAC1 was selected based on the expression patterns of a genome-wide dataset of RNA sequencing. Many jacalin-related lectin genes have been shown to be associated with disease resistance, biotic and abiotic stress signaling. Therefore, we studied its expression pattern in response to different abiotic stress and phytohormone treatments. The expression patterns of OsJAC1 under two different abiotic stress conditions (salt and heat stress) and phytohormones (salicylic acid and methyl jasmonate) were examined. The transcripts of OsJAC1 were significantly induced in response to abiotic stress conditions, including salt and heat treatments. In addition, it was induced in response to the salicylic acid and methyl jasmonate treatments, respectively. To investigate the sub-cellular localization of OsJAC1, the gene was expressed as a fusion protein tagged with GFP, in tobacco leaf epidermis and examined under confocal microscope. The OsJAC1 was clearly localized at the nucleus. These results provide critical insights into the molecular functions of the rice jacalin-like lectin domain containing proteins as receptors of external signals.

국내 바이오에탄올 혼합연료유 도입을 위한 실증평가연구

임의순(Yim, Eui-Soon),민경일(Min, Kyung-Il),전철환(Jeon, Cheol-Hwan),이돈민(Lee, Don-Min),김종렬(Kim, Jong-Ryeol),김승수(Kim, Seung-Soo),장은정(Jang, Eun-Jung),박천규(Park, Cheon-Kyu),정충섭(Jung, Chung-Sub),김재곤(Kim, Jae-Kon),임 한국신재생에너지학회 2007 한국신재생에너지학회 학술대회논문집 Vol.2007 No.11

국제 원유가의 지속적인 상승에 따라 화석연료 고갈을 대비한 대체에너지 빛 온실가스배출감소를 위하여 바이오연료의 사용 및 상용보급은 전세계적인 추세이다. 우리나라의 경우 바이오디젤은 2002년부터 시범보급사업(Demonstration & dissemination)을 거쳐 2006년 7월부터 전국주유소를 통하여 경유 중에 바이오디젤 0.5%를 혼합한 BDO.5를 수송용 연료로 도입하여 아시아 최초로 상용보급화를 시행하고 있다. 또한 휘발유 중 바이오에탄올 혼합 연료유 도입을 위한 실증평가연구를 2006년 8월부터 2008년 7월까지 수행중이다. 자동차용 휘발유의 옥탄가 향상을 위해 함산소 기재로 사용되는 MTBE(Methyl Tertiary Butyl Ether)를 바이오에탄올로 대체한 바이오에탄올 혼합연료유는 수분 혼입에 의한 상 분리(Phase separation)와 금속에 대한 부식성 문제를 야기 시킬 수 있다. 바이오에탄올을 서브옥탄가솔린(Sub-octane gasoline)에 혼합하여 상 분리 모사실험, 금속류 부식시험, 고무류 침지실험 등 다양한 품질특성평가를 수행하였으며, 이런 결과들을 바탕으로 국내실정에 알맞은 최적의 혼합량(E3, E5)을 도출하였다. 또한 전국에 4개 시범주유소를 운영하여 바이오에탄올 혼합 연료유의 유통 및 보급을 통해 최적의 유통인프라(Distribution infrastructure) 보완 및 구축 방안을 도출 하고자 한다.

국내 바이오에탄올 혼합연료유 도입을 위한 실증평가연구

임의순(Yim, Eui-Soon),민경일(Min, Kyung-Il),전철환(Jeon, Cheol-Hwan),이돈민(Lee, Don-Min),김종렬(Kim, Jong-Ryeol),김승수(Kim, Seung-Soo),장은정(Jang, Eun-Jung),박찬규(Park, Cheon-Kyu),정충섭(Jung, Chung-Sub),김재곤(Kim, Jae-Kon),임 한국신재생에너지학회 2007 신재생에너지 Vol.3 No.4

국제 원유가의 지속적인 상승에 따라 화석연료 고갈을 대비한 대체에너지 및 온실가스배출 감소를 위하여 바이오연료의 시용 및 상용보급은 전세계적인 추세이다. 우리나라의 경우 바이오디젤은 2002년부터 시범보급사업(Demonstration & disseminatio을 거쳐 2000년 7월부터 전국주유소를 통하여 경유 중에 바이오디젤 0.5%를 혼합한 BD0.5를 수송용 연료로 도입하여 아시아 최초로 상용보급화를 시행하고 있다. 또한 휘발유 중 바이오에탄올 혼합 연료유 도입을 위한 실증평가연구를 2006년 8월부터 2008년 7월까지 수행중이다. 자동차용 휘발유의 옥탄가 향상을 위해 함산소 기재로 사용되는 MTBE(Methyl Tertiary Butyl Ether)를 바이오에탄올로 대체한 바이오에탄올 혼합연료유는 수분 혼입에 의한 상 분리(Phase separation)와 금속에 대한 부식성 문제를 야기 시킬 수 있다. 바이오에탄올을 서브옥란가솔린(Sub-octane gasoline)에 혼합하여 상 분리 모사실험, 금속류 부식시험, 고무류 침지실험 등 다양한 품질특성평가를 수행하였으며, 이런 결과들을 바탕으로 국내실정에 알맞은 최적의 혼합량(E3, E5)을 도출하였다. 또한 전국에 4개 시범주유소를 운영하여 바이오에탄올 혼합 연료유의 유통 및 보급을 통해 최적의 유통인프라(Distribution infrastructure) 보완 및 구축 방안을 도출 하고자 한다.

일부 직업인의 건강증진생활양식에 영향을 미치는 요인 연구

이은경,안병상,유택수,김성천,정재열,박용신,장두섭,송용선,이기남,Lee Eun-Kyoung,An Byung-Sang,Yu Taek-Su,Kim Seoung-Cheon,Jeung Jea-Yeal,Park Young-Shin,Jahng Doo-Sub,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2000 대한예방한의학회지 Vol.4 No.2

The current industrial health service is shifting to health improvement business with 1st primary prevention-focused service from secondary and tertiary prevention-focused business, and Oriental medicine can provide such primary prevention-focused service due to the characteristics of its science. In particular, the advanced concept of health improvement can match the science of health care of Oriental medicine. Notably, what is most important in health improvement is our lifestyle, This does not underestimate the socio-environmental factors, which have lessened their importance due to modernism. The approach of Oriental medicine weighs more individuals' lifestyle and health care through self-cultivation. This matches the new model of advanced health business. Oriental medicine is less systemized than Western medicine, but it can provide ample contents that enhance health. If we conceive health-improvement program based on the advantages provided by these two medical systems, this will influence workers to the benefit of their health. Also, health Program needs to define factors that determine individual lives, and to provide information and technologies essential to our lives. The Oriental medicine approach puts more stress on a subject's capabilities than it does on the effect his surrounding environment can have. This needs to be supported theoretically by not only defining the relations between an individual's health state and his lifestyle, but also identifying the degree to which an individual in the industrial work place practices health improvement lifestyle . This is the first step toward initiating health-improvement business . In order to do this, this researcher conducted a survey by taking random samplings from workers, and can draw the following conclusions from it. 1 The sampled group is categorized into', by sender, female 6.6%, and male 93.4%, with males dominant; by marriage status , unmarried 43.9% and married 55.6%, with both similar percentage, and, by age, below 30, 48.4%, between 30 and 39, 27.4%, between 40 and 49, 18.2%, and over 50, 6.0%. The group further is categorized into; by education, middle school or under 1.7%, high school 30.5%, and junior college or higher 65.8% with high school and higher dominant: and by income, below 1.7 million won 24.2%, below 2.4 million won 14.8%, and above 2.4 million 6.3% Still, the group by job is categorized into collegians with 23.9%, office worker with 10.3%, and professionals with 65.8% , and this group does not include workers engaged in production that are needed for this research, but mostly office workers . 2. The subjects selected for this survey show their degree of practicing health-improvement lifestyle at an average of 2.63, health management pattern at 2.64, and health-related awareness at 2.62 The sub-divisions of health-improvement lifestyle show social emotion (2.87), food (2.66). favorite food (2.59), and leisure activities (2.52), in this order for higher points. It further shows health awareness (2.47) and safety awareness (2.40), lower points than those in health management pattern . 3. In the area of using leisure time for health-improvement, males, older people, married, and people with higher income earn higher marks. And, in the area of food management, the older and married earn higher marks . In the area of favorite food management, females, lower-income bracket, and lower-educated show higher degree of practice , while in the area of social emotion management, the older. married, and higher-income bracket show higher marks. In addition, in the area of health awareness, the older, married, and people with higher-income show higher degree of practice. 4. To look at correlation by overall and divisional health-improvement practice degree , this researcher has analyzed the data using Person's correlation coefficient. The lifestyle shows significant correlation with its six sub-divisions, and use of leisure time, food, and health awareness al

Cu(Ⅱ)이온과 Poly(vinyl alcohol)간에 생성되는 고분자-금속 착물의 열역학적 거동에 관한 연구

전은덕, 한정호, 조태섭 영남대학교 기초과학연구소 2000 基礎科學硏究 Vol.20 No.-

The dissociation constants for poly(vinyl alcohol) (PVA) at a constant ionic strength of μ=0.1(KCl) were measured by potentiometric titration at various temperatures. The formation constants for the Cu(II)-PVA complex at the same condition were also measured in this study. From the temperature dependence of those dissociation and formation constants, various thermodynamic parameters such as ΔG, ΔH, ΔS were determined. From the thermodynamic parameters, it was concluded that the dissociation of a proton from PVA is unfavorable with a negative entropy and positive enthalpy. In contrast, the complex formation was a spontaneous and exothermic process with favorable entropy.