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        Robotic single site versus robotic multiport hysterectomy in early endometrial cancer: a case control study

        Giacomo Corrado,Giuseppe Cutillo,Emanuela Mancini,Ermelinda Baiocco,Lodovico Patrizi,Maria Saltari,Anna di Luca Sidozzi,Isabella Sperduti,Giulia Pomati,Enrico Vizza 대한부인종양학회 2016 Journal of Gynecologic Oncology Vol.27 No.4

        Objective: To compare surgical outcomes and cost of robotic single-site hysterectomy (RSSH) versus robotic multiport hysterectomy (RMPH) in early stage endometrial cancer. Methods: This is a retrospective case-control study, comparing perioperative outcomes and costs of RSSH and RMPH in early stage endometrial cancer patients. RSSH were matched 1:2 according to age, body mass index, comorbidity, the International Federation of Gynecology and Obstetric (FIGO) stage, type of radical surgery, histologic type, and grading. Mean hospital cost per discharge was calculated summarizing the cost of daily hospital room charges, operating room, cost of supplies and length of hospital stay. Results: A total of 23 women who underwent RSSH were matched with 46 historic controls treated by RMPH in the same institute, with the same surgical team. No significant differences were found in terms of age, histologic type, stage, and grading. Operative time was similar: 102.5 minutes in RMPH and 110 in RSSH (p=0.889). Blood loss was lower in RSSH than in RMPH (respectively, 50 mL vs. 100 mL, p=0.001). Hospital stay was 3 days in RMPH and 2 days in RSSH (p=0.001). No intraoperative complications occurred in both groups. Early postoperative complications were 2.2% in RMPH and 4.3% in RSSH. Overall cost was higher in RMPH than in RSSH (respectively, $7,772.15 vs. $5,181.06). Conclusion: Our retrospective study suggests the safety and feasibility of RSSH for staging early endometrial cancer without major differences from the RMPH in terms of surgical outcomes, but with lower hospital costs. Certainly, further studies are eagerly warranted to confirm our findings.

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        Effect of alginate coating on the physico-chemical and microbial quality of pansies (Viola 3 wittrockiana) during storage

        Luana Fernandes,Susana Casal,Jose´ A. Pereira,Ermelinda L. Pereira,Jorge A. Saraiva,Elsa Ramalhosa 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.4

        Edible flowers, such as pansies, are becoming more popular, but they are highly perishable. So, postharvest technologies are needed, being edible coatings a good alternative. Thus, the aim of this study was to evaluate the effect of alginate coating on physico-chemical and microbiological quality of pansies during cold storage (4 C for 0, 7, 14, 21 days). Coated pansies maintained good appearance until 14 days of storage, 7 days more than uncoated ones. Flavonoids, hydrolysable tannins and monomeric anthocyanins, as well antioxidant activity, were higher in coated pansies when compared to uncoated ones, on all assayed storage times. Furthermore, after 14 days of storage, uncoated pansies presented microorganism counts higher than coated, namely yeasts and moulds, suggesting an effective barrier protection of the alginate coating treatment. In summary, alginate coating has potential for extending shelf-life and improving physico-chemical and microbiological quality of pansies.

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        Robotic single site radical hysterectomy plus pelvic lymphadenectomy in gynecological cancers

        Enrico Vizza,Benito Chiofalo,Giuseppe Cutillo,Emanuela Mancini,Ermelinda Baiocco,Ashanti Zampa,Arabella Bufalo,Giacomo Corrado 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.1

        Objective: To evaluate the feasibility and the safety of robotic single-site radical hysterectomy (RSSRH) plus pelvic lymphadenectomy (PL) in endometrial or cervical cancer. Methods: Patients with endometrial cancer (EC) International Federation of Gynecology and Obstetrics (FIGO) stage II, early cervical cancer (ECC) FIGO stage IB1 or locally advanced cervical cancer (LACC) FIGO stage IB2–IIB with clinical response ≥50% after neo-adjuvant chemotherapy (NACT) were enrolled in a prospective cohort trial. All cases were performed using the da Vinci Si Surgical Single Site System®. Results: Between April 2014 and November 2016, twenty patients were included in our pilot study. Three and 17 patients underwent type B1 or C1 RSSRH plus PL, respectively. The median age of patients was 46 years (range, 36–68 years) and the median body mass index was 23.5 kg/m2 (range, 19.1–36.3 kg/m2). The median total operative time was 190 minutes (range, 90–310 minutes). The median blood loss was 75 mL (range, 20–700 mL) and the median number of pelvic lymph nodes removed was 16 (range, 5–27). No laparoscopic/laparotomic conversions were reported and the median time to discharge was 6 days (range, 4–16 days). No intra-operative complications occurred while 4 (20%) post-operative complications were reported: one pelvic abscess, one lymphorrea, one bowel perforation, and one vaginal dehiscence. Conclusion: RSSRH plus PL is technically feasible in patients affected by gynecological cancer.

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