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Encinas-Basurto David,Eedara Basanth Babu,Mansour Heidi M. 한국약제학회 2024 Journal of Pharmaceutical Investigation Vol.54 No.2
Background Pulmonary drug delivery is an efficient way to deliver drugs directly to the site of action i.e., lungs or to the blood circulation with minimum systemic effects. Recent emergence of coronavirus disease-2019 (COVID-19) and expeditious development of nanoparticle-based vaccines have recently reignited considerable interest in designing inhalable nanoparticle-based drug delivery systems as next-generation respiratory therapeutics. Area covered In this review, dry powder inhaler (DPI) formulations based on polymeric nanoparticles have been reviewed. It comprehensively describes various biodegradable and biocompatible synthetic (e.g. polylactic-glycolic acid, polyethylene glycol, polyethylenimine, and polycaprolactone) and natural (e.g. alginate, chitosan, dextran, hyaluronic acid, and gelatin) polymers used in formulating nanoparticle-based dry powder inhalers. This review covers the most recent drugs encapsulated in synthetic-based and natural-based biocompatible nanocarriers used in DPIs, providing latest approaches for treating various respiratory and pulmonary disorders. Expert Opinion DPIs comprised of biocompatible biodegradable polymeric nanocarriers exhibited favorable particle properties and aerodynamic properties. In addition, these polymeric nanocarriers are chemically versatile in being either synthetic or natural. This chemical versatility enables versatility in the various types of drugs that can be incorporated into DPIs provided that the needed particle properties and aerodynamic properties are maintained.
Jose de Jesus Encinas-Arzate,Josafat Marina Ezquerra-Brauer,Victor Manuel Ocaño-Higuera,Benjamin Ramirez-Wong,Lorena Armenta-Villegas,Wilfrido Torres-Arreaola,Enrique Marquez-Rios 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.2
Myofibrillar protein are the principally responsibleof gelling properties in fishery resource, hence, during proteinconcentrate or isolated proteins preparation, sarcoplasmicprotein are discarded; however, myofibrillar protein cansupport low levels of sarcoplasmic proteins without affectingthe gelling property. Therefore, the aim of this study was togradually remove sarcoplasmic proteins from giant squidmantle by means of different ionic strengths (I). Solutionsof NaCl with different ionic strengths (I=0.0, 0.1, and 0.3)were used to obtain 3 protein concentrates. The electrophoreticprofile in SDS-PAGE showed differences in protein removalwith a high solubility of mantle proteins. The texture profileanalysis showed that hardness increased in mantle proteinwashed with higher I. The total reactive sulfhydryls showedsignificant changes (p<0.05) detecting major formation ofS-S bonds with protein removal at an I of 0.3. Differentialscanning calorimetry showed a minor denaturation temperatureof the actomyosin complex when protein removal wasperformed with an I of 0.3. The present study indicates thatremoval of sarcoplasmic protein as a function of I results inbetter quality gels.
STRONG PRESERVERS OF SYMMETRIC ARCTIC RANK OF NONNEGATIVE REAL MATRICES
Beasley, LeRoy B.,Encinas, Luis Hernandez,Song, Seok-Zun Korean Mathematical Society 2019 대한수학회지 Vol.56 No.6
A rank 1 matrix has a factorization as $uv^t$ for vectors u and v of some orders. The arctic rank of a rank 1 matrix is the half number of nonzero entries in u and v. A matrix of rank k can be expressed as the sum of k rank 1 matrices, a rank 1 decomposition. The arctic rank of a matrix A of rank k is the minimum of the sums of arctic ranks of the rank 1 matrices over all rank 1 decomposition of A. In this paper we obtain characterizations of the linear operators that strongly preserve the symmetric arctic ranks of symmetric matrices over nonnegative reals.
Strong preservers of symmetric arctic rank of nonnegative real matrices
비어슬리,Luis Hernandez Encinas,송석준 대한수학회 2019 대한수학회지 Vol.56 No.6
A rank $1$ matrix has a factorization as ${\bf u}{\bf v}^t$ for vectors ${\bf u}$ and ${\bf v}$ of some orders. The arctic rank of a rank $1$ matrix is the half number of nonzero entries in ${\bf u}$ and ${\bf v}$. A matrix of rank $k$ can be expressed as the sum of $k$ rank $1$ matrices, a rank $1$ decomposition. The arctic rank of a matrix $A$ of rank $k$ is the minimum of the sums of arctic ranks of the rank $1$ matrices over all rank $1$ decomposition of $A$. In this paper we obtain characterizations of the linear operators that strongly preserve the symmetric arctic ranks of symmetric matrices over nonnegative reals.
EXTREME PRESERVERS OF MAXIMAL COLUMN RANK INEQUALITIES OF MATRIX MULTIPLICATIONS OVER SEMIRINGS
송석준,박권룡,L. Hernandez Encinas 대한수학회 2010 대한수학회지 Vol.47 No.1
We characterize linear operators that preserve sets of matrix ordered pairs which satisfy extreme cases with respect to maximal column rank inequalities of matrix multiplications over semirings.
속보 : 위성사진과 지리정보체계(GIS)에 의한 브라질 서부농장지역의 토지이용구분과 인공조림계획에 관한 연구 -Mato Grosso do Sul 주의 장가다 및 쟈마이카 농장
우종춘 ( Jong Choon Woo ),죠세이마나엔시나스 ( Jose Imana Encinas ) 大韓遠隔探査學會 2000 大韓遠隔探査學會誌 Vol.16 No.3
본 연구에서는 브라질 서부의 Mato Grosso do Sul 주에 위치하는 장가다. 쟈마이카 두 개의 농장에 유칼리나무 인공조림블록단지를 위한 식재계획을 세워 보았다. 우선 위성사진을 분석하고 GIS에 의해서 현상태대로의 토지이용구분 빛 산림식생구분을 하였고 이것을 기초로 하여 조림가능지역을 계산하였다. 그리고 농장주인의 요구에 따라 조림가능지역에 대한 식재계획을 3차년도까지 수립하였다. 두 개의 농장 총면적은 5,301ha이며 조림가능면적은 3,913ha로서 전체면적의 74%에 해당하는 것으로 추정되었다. 그리고 나머지 26%에 해당하는 1,388ha의 면적은 산림법상 영구보존시켜야 할 산림식생 면적으로 추정되었다. 토양손실을 최소화하기 위해서 등고선에 따라 구획한 조림블록은 1년차에 27개 블록으로 총 1,308.8ha에 이르고, 2년차에도 27개 블록에 l,327.4ha, 그리모 3년차에는 30개 블록에 1,276.5ha의 면적으로 구획되었다. In this study tree plantation planning for the plantation blocks of Eucalyptus species was constructed in order to apply to the two farms Jamaica and Jamaica, where are located in the western district of the state Mato Grosso do Sul in Brazil. At first the satellite photo was analyzed for the land use classification and the forest ecosystem was classified with GIS technique, and then on the basis of this result the planting available area was accounted for the two farms. According to the request of the land owner the planting planning was established for the planting available area for 3 years. The total area for the two farms is 5,301ha, and the planting available area is estimated to be 3,913ha(74%). The rest area is 1,388ha(26%), and should be classified to the permanent legal reserve forest area. In order to minimize the soil loss and the erosion, the planting blocks were divided according to the parallel to the contour line: for the first planning year the plantation area was divided to the 27 blocks and the total area was 1,308.8ha, for the second planning year the area also divided to 27 blocks(1,327.4ha) and for the third planning year 30 blocks divided(1276.5).
NONNEGATIVE INTEGRAL MATRICES HAVING GENERALIZED INVERSES
Kang, Kyung-Tae,Beasley, LeRoy B.,Encinas, Luis Hernandez,Song, Seok-Zun Korean Mathematical Society 2014 대한수학회논문집 Vol.29 No.2
For an $m{\times}n$ nonnegative integral matrix A, a generalized inverse of A is an $n{\times}m$ nonnegative integral matrix G satisfying AGA = A. In this paper, we characterize nonnegative integral matrices having generalized inverses using the structure of nonnegative integral idempotent matrices. We also define a space decomposition of a nonnegative integral matrix, and prove that a nonnegative integral matrix has a generalized inverse if and only if it has a space decomposition. Using this decomposition, we characterize nonnegative integral matrices having reflexive generalized inverses. And we obtain conditions to have various types of generalized inverses.