Results of Surgical Treatment of Liver Alveococcosis with Main Vessels Budding

( Edir Surov ),( Bakhadyr Bebezov ),( Tilek Umetaliev ),( Nurlan Mama Shev ),( Erlan Murzaliev ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: To improve the results of surgical treatment of liver alveococcosis with the budding of the main vessels Methods: We analyzed the results of surgical treatment of 77 patients diagnosed with liver alveococcosis with the budding of its main vessels: the inferior vena cava, portal vein and / or its branches, hepatic veins. All patients were hospitalized in the National Hospital under Ministry of Health of The Republic of Kyrgyzstan named after I.K Akhunbayev. The observation period was from 2009 to 2017. There were 27 men (35%), women - 50 (65%) out of 77 patients. The age range of the patients was from 15 to 65 years; the average age of the patients was 34.8 ± 1.4 years. 73 (94.8%) patients were at the able-bodied age. All patients were divided into three groups depending on the vascular injury: the first group - patients with liver alveococcosis with injury of the vena cava inferior - 42 (54.5%), the second group - with injury of the portal vein and / or its branches - 28 (36.3%), the third group - with injury of the hepatic veins - 7 (9.2%). Results: The resection of the liver was performed in 32 patients; there were marginal resection of the vena cava inferior in 7 cases, with resection and prothesis of the vena cava inferior and left hepatic vein in one cases. Surgical treatment had curative character in 8 cases, which was 19%. The were 24 cases of liver resection in the second group including marginal resection of portal vein in 2 cases and circular resection of the portal vein with the imposition of the porto-porto anastomosis “end-to-end” in 3 cases. Surgical treatment had curative character in 19 cases, which was 70%. There were 1 case with resection of the left and middle hepatic veins, 2 case with resection of the middle of the hepatic vein and 2 case with resection of the mouth of the right hepatic vein included in the third group of patients with injury of the proper hepatic veins. Surgical treatment had curative character in 6 cases which was 86%. Conclusions: It is possible to perform a radical operation due to combined intervention on vessels and / or inferior vena cava in 48.1% of patients despite the growth of LIP and portal vein. Liver recovery with resection and / or reconstruction of the main vessels is an alternative to liver transplantation.

PTBD in the Treatment of Patients with Alveococcus of the Liver, Complicated by Mechanical Jaundice

( Edir Surov ) 대한간학회 2021 춘·추계 학술대회 (KASL) Vol.2021 No.1

Liver Alveococcosis, ICV, Surgical Treatment

( Bahadyr Bebezov ),( Edir Surov ),( Tilek Umetaliev ),( Nurlan Mamashev ),( Erlan Murzaliev ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: On the territory of Kyrgyzstan to endemic regions are Alai and Chon-Alai region of Osh oblast, At-Bashy and Kochkor region of Naryn oblast. The percentage of complicated forms of liver alveococcosis according to different authors varies from 34% to 80%. Methods: From April 2009 to August 2016 on the treatment in the clinic named after I.K. Ahunbaeva National Hospital were 290 patients with liver alveococcosis. In 42 (14.4%) patients alveococcosis sprout in the NIP. Men were 11 (26.2%), women - 31 (73.8%). The average age of patients was 33,8 ± 1,9 years. According to the classification PNM patients were distributed as follows: P4N0M0 - 24, P4N0M1 - 2 (with metastases in the lungs), P4N1M0 - 15 patients, P4N1M1 - 1. Results: Completed operations: · Expanded right hemihepatectomy - 11 (with resection and prosthetic IVC and left hepatic vein resection and reconstruction of portal vein resection and reconstruction of the extrahepatic bile duct external drainage of the bile duct 1, a wedge resection of the NIP - 2, palliative - 8,) · right hemihepatectomy - 10 (with edge resection of IVC -3, palliative- 6;) · expanded left hemihepatectomy -2 (palliative); · atypical resections - 5 (AR S3, S5, S7 and S4 from the edge resection of IVC -1 palliative -4); · cytoreductive resection - 2; · S1 resection with wedge resection of the NIP - 1; · removal of alveolar node S4 liver (left plate on NIP) -1; · opening and drainage of alveolar cyst -3; · Exploratory laparotomy - 7. Submitted forty-two liver resections: 8 (19.9%) of radical liver re section and palliative operations - 34 (80.1%). Palliative operated patients received albendazole for the standard scheme Conclusions: Although a circular lesion of the inferior vena cava alveococcosis liver, possible radical resection liver resection and grafting lesion IVC and portal vein.

Results of Extensive Resections with Focal Liver Lesions

( Bakhadyr Bebezov ),( Edir Surov ),( Nurlan Mamashev ),( Tilek Umetaliev ),( Erlan Murzaliev ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: To evaluate the results of extensive liver resections with focal lesions of the liver. Methods: There were 445 patients with focal liver damage in the National Hospital named after Akhunbayev from April 2009 to December 2017. The main part of patients was patients with alveococcosis of the liver - 358 patients; metastases of colorectal cancer - 34 patients; hepatocellular carcinoma - 25 cases; hemangiomas - 23, cholangiocellular carcinoma - 3 cases of observations and 2 cases with fibronodular hyperplasia. 393 patients had surgical treatment from 445 totally, which was 88.3%. There were 193 patients with extensive liver resections, which was -49.1%. The men were 67 (34.7%), women 126 (65.3%). The age range of patients was from 14 to 73 years, the average age of patients was 44 ± 2.3 years. Results: Performed surgical resections: right hemihepatectomy was in 88 cases, which was 45.6%, resection of extrahepatic bile ducts in 3 cases, with portal vein resection in 3 cases and with resection of vena cava inferior in 7 cases. Left hemihepatectomy was performed in 37 cases, 2 patients with resection of extrahepatic ducts. Extra right hemihepatectomy was performed in 46 patients, resection of extrahepatic bile ducts in 4 cases, portal vein resection in 3 cases and vena cava inferior resection in 3 cases, Extra left hemihepatectomy was performed in 22 cases, resection of extrahepatic bile ducts in 2 cases. It should be emphasized that the expanded hemihepatectomies come up to 35.2%! Conclusions: The main reason of development of massive bleeding at extensive liver resections is mainly due to damage of hepatic veins in the caval gates or inferior vena cava. It’s preferred to perform extensive liver resection by a collar way, which allows reducing peroperative blood loss.

Immediate Results of Surgical Treatment of Metastasis of Colorectal Cancer of the Treatment

( Erlan Murzaliev ),( Bebezov Bakhadyr ),( Edir Surov ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Evaluation of the results of surgical treatment of CRC metastasis in the liver. Methods: The results of treatment of 34 patients with metastases of colorectal cancer in the liver from 2010 to 2017 are analyzed. There were 19 men (55.8%), women-15 (44.1%). The average age of the patients was 37 ± 85 yearsold.There localization of metastasis are in the left lobe - 5 patients, right lobe - 24 patients and bilobate liver damage - 6 patients. According to the international mTNM classification IwatsukiS.C. with et al. 1986 metastasis of colorectal cancer in the liver patients were distributed as follows: mT2N0M0 (stage II) - 19, mT3N0M0 (III stage) - 10, mT4N0M0 (IVA stage) - 4 patients, mT4N1M1 (IVB stage) -1. Results: The following types of liver resection were performed: PGEGE-17, LGGE-2, atypical resections-2, bisegmentectomy -8, trisegmentectomy-3, LLE-1, explorative laparotomy-1. The average loss of blood was 798 ± 256ml., мinimal 200 ml. . 6 patients had hepatic insufficiency in the postoperative session, received conservative therapy; All patients received adjuvant chemotherapy according to the XELOX scheme, FOLFOX. Postoperative mortality was 2.9% (1 patient). Results: The following types of liver resection were performed: PGEGE-17, LGGE-2, atypical resections-2, bisegmentectomy -8, trisegmentectomy-3, LLE-1, explorative laparotomy-1. The average loss of blood was 798 ± 256ml., мinimal 200 ml. . 6 patients had hepatic insufficiency in the postoperative session, received conservative therapy; All patients received adjuvant chemotherapy according to the XELOX scheme, FOLFOX. Postoperative mortality was 2.9% (1 patient). Conclusions: The tactic of surgical treatment of metastatic liver cancer should be active, liver resection can be performed in patients with sufficient functional reserve of the organ.Performance of anatomic resections of the liver is more preferable. The closest results of treatment of this category of patients justify the proposed treatment tactics.

Bacterial Structure and Characterization of Plant Growth Promoting and Oil Degrading Bacteria from the Rhizospheres of Mangrove Plants

Flávia Lima do Carmo,Henrique Fragoso dos Santos,Edir Ferreira Martins,Jan Dirk van Elsas,Alexandre Soares Rosado,Raquel Silva Peixoto 한국미생물학회 2011 The journal of microbiology Vol.49 No.4

Most oil from oceanic spills converges on coastal ecosystems, such as mangrove forests, which are threatened with worldwide disappearance. Particular bacteria that inhabit the rhizosphere of local plant species can stimulate plant development through various mechanisms; it would be advantageous if these would also be capable of degrading oil. Such bacteria may be important in the preservation or recuperation of mangrove forests impacted by oil spills. This study aimed to compare the bacterial structure, isolate and evaluate bacteria able to degrade oil and stimulate plant growth, from the rhizospheres of three mangrove plant species. These features are particularly important taking into account recent policies for mangrove bioremediation,implying that oil degradation as well as plant maintenance and health are key targets. Fifty-seven morphotypes were isolated from the mangrove rhizospheres on Bushnell-Haas (BH) medium supplemented with oil as the sole carbon source and tested for plant growth promotion. Of this strains, 60% potentially fixed nitrogen, 16% showed antimicrobial activity, 84% produced siderophores, 51% had the capacity to solubilize phosphate, and 33% produced the indole acetic acid hormone. Using gas chromatography, we evaluated the oil-degrading potential of ten selected strains that had different morphologies and showed Plant Growth Promoting Rhizobacteria (PGPR) features. The ten tested strains showed a promising degradation profile for at least one compound present in the oil. Among degrader strains, 46% had promising PGPR potential, having at least three of the above capacities. These strains might be used as a consortium,allowing the concomitant degradation of oil and stimulation of mangrove plant survival and maintenance.