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      • KCI등재

        A comparison of liveweight gain of lambs weaned early onto a herb-clover mixed sward and weaned conventionally onto a ryegrass-clover pasture and herb-clover mixed sward

        W.E.M.L.J. Ekanayake,R.A. Corner-Thomas,L. M. Cranston,P.R. Kenyon,S.T. Morris 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.2

        Objective: The aim of the present study was to identify the impact of early weaning of lambs at approximately seven weeks of age onto a herb-clover mix on the liveweight gain of lambs and their dams. Methods: In 2015, twin-born lambs that weighed a minimum of 16 kg (n = 134) were randomly allocated to one of three treatments: i) Early-weaned (58 days after the midpoint of lambing) onto an unrestricted allowance (>1,200 kg dry matter/ha) of herb-clover mix (HerbEW); ii) Lambs+dams unweaned onto an unrestricted allowance of herb-clover mix until conventional weaning (95 days after the midpoint of lambing) (HerbCW); iii) Lambs+ dams unweaned onto an unrestricted allowance of grass-clover pasture until conventional weaning (GrassCW). In 2016, twin-born lambs that weighed a minimum of 16 kg (n = 170) were randomly allocated to one of four treatments: i), ii), iii) (similar to 2015) and iv) Lambs+ dams unweaned onto a restricted allowance (<1,200 kg dry matter/ha) of grass-clover pasture until conventional weaning (93 days after the midpoint of lambing) (Restricted-GrassCW). Results: In 2015, liveweight gain from L58 to L95 of HerbCW and GrassCW lambs did not differ (p>0.05), but were greater than HerbEW lambs. In 2016, HerbCW lambs had greater (p<0.05) liveweight gains from L51 to L93 than GrassCW followed by HerbEW and Restricted-GrassCW lambs. In 2015, liveweight gain from L58 to L95 of HerbEW ewes were greater than both GrassCW and HerbCW ewes while in 2016, liveweight gain of from L51 to L93 GrassCW and HerbCW ewes did not differ (p>0.05) but were greater (p<0.05) than those of HerbEW and Restricted-GrassCW ewes. Conclusion: These results indicate that when grass-clover pasture supply can be maintained at unrestricted intake level, there may be no benefit of weaning lambs early. However, at restricted pasture conditions lambs can achieve greater liveweight gains when weaned early onto a herb-clover mix.

      • 脫脂乳의 褐變化 抑制物質이 乳酸菌增殖과 酸生成에 미치는 影響 : 1. Inhibitors의 褐變化 抑制效果와 細菌數의 變化 1. Estimations of Bacterial population and Inhibition of Browning in skim milk

        이을희,강군중,오석두 진주산업대학교 1987 論文集 Vol.25 No.-

        抑制物質의 非酸素的 갈變化反應抑制效과와 L-cysteine의 添加가 세균 증식에 미치는 영향을 조사하여 다음과 같은 결론을 얻었다. 1. L-cysteine과 H_20_2는 첨가 수준이 높을수록 갈변화 억제효과가 크게 나타났다. 2. Glutamic acid는 억제효과가 거의 없었다. 3. 250˚F(15min)살균의 경우는 L-cysteine이, 240˚F(30min) 및 230˚F(60min)에서는 H_20_2가 억제효과가 큰것으로 나타났다. 4. L-cysteine(0.04%, w/v)첨가시 Str. feacalis의 증식속도는 무첨가구에 비해 다소 빠른 것으로 나타났고 L. acidophilus의 경우는 13시간 까지 뚜렷한효과가 없었다. Effect of inhibitors on nonenzymatic browning reaction and L-cysteine added in the autoclaved skim milk on the growth of lactic acid bacteria were studied, and the results were as follows: 1. Glutamic acid failed to inhibit browning of milk, whereas L-cysteine and H_2O_2(Hydrogen peroxide) were inhibitory to browning as the concentrations of them increase. 2. The inhibitory effect of L-cysteine was increased in the autoclaved in the condition of 250˚F for 15 minutes, whereas that of H_2O_2 was increased in the condition of 240˚F for minutes and 230˚F for 60 minutes. 3. The growth rate of Str. feacalis in the medium added L-cysteine(0.04%, w/v) was found to be a little more faster than that in the blank. In the case of L. acidophilus, there was not clear effect until 13 hours' fermentation.

      • SCISCIESCOPUS

        Interaction of silver(I) and copper(I) with an O<sub>2</sub>S<sub>2</sub>-macrocycle - A comparative structural study

        Kim, S.,Lee, E.,Lee, S.Y.,Lee, S.S.,Lindoy, L.F. Elsevier Sequoia [etc.] 2014 Inorganica chimica acta Vol.417 No.-

        The 14-membered O<SUB>2</SUB>S<SUB>2</SUB>-macrocycle L reacts with AgPF<SUB>6</SUB> in acetonitrile/dichloromethane (1:1) to yield the cyclic, double S-Ag-S bridged complex, [Ag<SUB>2</SUB>L<SUB>2</SUB>(CH<SUB>3</SUB>CN)<SUB>4</SUB>](PF<SUB>6</SUB>)<SUB>2</SUB> (2), in which each Ag(I) is bound to two exo-oriented S donors arising from different macrocycles to form a 12-membered, di-Ag metallacycle. Two PF<SUB>6</SUB><SUP>-</SUP> ions form weak intramolecular contacts [Ag...F, 2.925(2)A] between the Ag centres in a bridging bidentate fashion. The coordination sphere of each Ag is completed by two weakly bound acetonitrile molecules. The respective macrocyclic ligands are arranged trans to the mean plane through the metallacycle. When the above synthetic procedure was repeated employing methanol/dichloromethane (1:1) as solvent, a complex of type [Ag<SUB>2</SUB>L<SUB>2</SUB>](PF<SUB>6</SUB>)<SUB>2</SUB> (3) was obtained whose structure incorporates a similar 12-membered metallacycle but with the respective macrocyclic rings now oriented towards the same side of the metallacyclic plane. The reaction of L with AgCF<SUB>3</SUB>SO<SUB>3</SUB> yields [Ag<SUB>2</SUB>L<SUB>2</SUB>(CF<SUB>3</SUB>SO<SUB>3</SUB>)<SUB>2</SUB>].2CH<SUB>3</SUB>CN (4) whose structure resembles that of [Ag<SUB>2</SUB>L<SUB>2</SUB>(CH<SUB>3</SUB>CN)<SUB>4</SUB>](PF<SUB>6</SUB>)<SUB>2</SUB> (2); each complex unit incorporates a di-Ag(I) 12-membered metallacycle, with symmetrical bridging bidentate CF<SUB>3</SUB>SO<SUB>3</SUB><SUP>-</SUP> ions weakly linking Ag centres. Long Ag1...Ag1C contacts are present between pairs of complex units. Reaction of Cu(CH<SUB>3</SUB>CN)<SUB>4</SUB>PF<SUB>6</SUB> (one equiv.) with L in methanol/dichloromethane (1:1) resulted in isolation of [CuL<SUB>2</SUB>]PF<SUB>6</SUB> (5) incorporating a distorted tetrahedral S<SUB>4</SUB>-coordination sphere, with each macrocycle binding as a bidentate ligand via its two (exo-orientated) S atoms. In contrast, reaction of [Cu(CH<SUB>3</SUB>CN)<SUB>4</SUB>]PF<SUB>6</SUB> (two equiv.) with L in either acetonitrile/dichloromethane (1:1) or methanol/dichloromethane (1:1) yielded [Cu<SUB>2</SUB>L<SUB>3</SUB>]PF<SUB>6</SUB> (6) in which the Cu(I) centres are bound exo to the macrocyclic cavity by individual S-donors from one L, with the coordination sphere of each Cu(I) completed by out-of-plane binding of the S<SUB>2</SUB>O donors from a second L. Unsymmetrical F...Cu contacts from a PF<SUB>6</SUB><SUP>-</SUP> anion weakly link the pair of Cu centres in a bridging bidentate fashion.

      • SCISCIE

        The SAURON project – XIX. Optical and near‐infrared scaling relations of nearby elliptical, lenticular and Sa galaxies

        Falcó,n‐,Barroso, J.,van de Ven, G.,Peletier, R. F.,Bureau, M.,Jeong, H.,Bacon, R.,Cappellari, M.,Davies, R. L.,de Zeeuw, P. T.,Emsellem, E.,Krajnović,, D.,Kuntschner, H.,McDermid, R. Blackwell Publishing Ltd 2011 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.417 No.3

        <P><B>ABSTRACT</B></P><P>We present ground‐based MDM Observatory <I>V</I>‐band and <I>Spitzer</I>/InfraRed Array Camera 3.6‐<IMG src='/wiley-blackwell_img/equation/MNR_19372_mu1.gif' alt ='inline image'/>m‐band photometric observations of the 72 representative galaxies of the SAURON survey. Galaxies in our sample probe the elliptical E, lenticular S0 and spiral Sa populations in the nearby Universe, both in field and cluster environments. We perform aperture photometry to derive homogeneous structural quantities. In combination with the SAURON stellar velocity dispersion measured within an effective radius (σ<SUB>e</SUB>), this allows us to explore the location of our galaxies in the colour–magnitude, colour–σ<SUB>e</SUB>, Kormendy, Faber–Jackson and Fundamental Plane scaling relations. We investigate the dependence of these relations on our recent kinematical classification of early‐type galaxies (i.e. slow/fast rotators) and the stellar populations. Slow rotator and fast rotator E/S0 galaxies do not populate distinct locations in the scaling relations, although slow rotators display a smaller intrinsic scatter. We find that Sa galaxies deviate from the colour–magnitude and colour–σ<SUB>e</SUB> relations due to the presence of dust, while the E/S0 galaxies define tight relations. Surprisingly, extremely young objects do not display the bluest (<I>V</I>−[3.6]) colours in our sample, as is usually the case in optical colours. This can be understood in the context of the large contribution of thermally pulsing asymptotic giant branch stars to the infrared, even for young populations, resulting in a very tight (<I>V</I>−[3.6])–σ<SUB>e</SUB> relation that in turn allows us to define a strong correlation between metallicity and σ<SUB>e</SUB>. Many Sa galaxies appear to follow the Fundamental Plane defined by E/S0 galaxies. Galaxies that appear offset from the relations correspond mostly to objects with extremely young populations, with signs of ongoing, extended star formation. We correct for this effect in the Fundamental Plane, by replacing luminosity with stellar mass using an estimate of the stellar mass‐to‐light ratio, so that all galaxies are part of a tight, single relation. The new estimated coefficients are consistent in both photometric bands and suggest that differences in stellar populations account for about half of the observed tilt with respect to the virial prediction. After these corrections, the slow rotator family shows almost no intrinsic scatter around the best‐fitting Fundamental Plane. The use of a velocity dispersion within a small aperture (e.g. <I>R</I><SUB>e</SUB>/8) in the Fundamental Plane results in an increase of around 15 per cent in the intrinsic scatter and an average 10 per cent decrease in the tilt away from the virial relation.</P>

      • KCI등재

        Demands and distribution of hysteretic energy in moment resistant self-centering steel frames

        Arturo López-Barraza,Sonia E. Ruiz,Alfredo Reyes-Salazar,Edén Bojórquez 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.20 No.5

        Post-tensioned (PT) steel moment resisting frames (MRFs) with semi-rigid connections (SRC) can be used to control the hysteretic energy demands and to reduce the maximum inter-story drift (<i>γ</i>). In this study the seismic behavior of steel MRFs with PT connections is estimated by incremental nonlinear dynamic analysis in terms of dissipated hysteretic energy (<i>E<sub>H</sub></i>) demands. For this aim, five PT steel MRFs are subjected to 30 long duration earthquake ground motions recorded on soft soil sites. To assess the energy dissipated in the frames with PT connections, a new expression is proposed for the hysteretic behavior of semi-rigid connections validated by experimental tests. The performance was estimated not only for the global <i>E<sub>H</sub></i> demands in the steel frames; but also for, the distribution and demands of hysteretic energy in beams, columns and connections considering several levels of deformation. The results show that <i>E<sub>H</sub></i> varies with <i>γ</i>, and that most of <i>E<sub>H</sub></i> is dissipated by the connections. It is observed in all the cases a log-normal distribution of <i>E<sub>H</sub></i> through the building height. The largest demand of <i>E<sub>H</sub></i> occurs between 0.25 and 0.5 of the height. Finally, an equation is proposed to calculate the distribution of <i>E<sub>H</sub></i> in terms of the normalized height of the stories (<i>h</i>/<i>H</i>) and the inter-story drift.

      • A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo

        Yoo, S.-H.,Ko, C. H.,Lowrey, P. L.,Buhr, E. D.,Song, E.-j.,Chang, S.,Yoo, O. J.,Yamazaki, S.,Lee, C.,Takahashi, J. S. Proceedings of the National Academy of Sciences 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.102 No.7

        <P>The mouse Period2 (mPer2) locus is an essential negative-feedback element of the mammalian circadian-clock mechanism. Recent work has shown that mPer2 circadian gene expression persists in both central and peripheral tissues. Here, we analyze the mouse mPer2 promoter and identify a circadian enhancer (E2) with a noncanonical 5'-CACGTT-3' E-box located 20 bp upstream of the mPer2 transcription start site. The E2 enhancer accounts for most circadian transcriptional drive of the mPer2 locus by CLOCK:BMAL1, is a major site of DNaseI hypersensitivity in this region, and is constitutively bound by a transcriptional complex containing the CLOCK protein. Importantly, the E2 enhancer is sufficient to drive self-sustained circadian rhythms of luciferase activity in central and peripheral tissues from mPer2-E2::Luciferase transgenic mice with tissue-specific phase and period characteristics. Last, genetic analysis with mutations in Clock and Bmal1 shows that the E2 enhancer is a target of CLOCK and BMAL1 in vivo.</P>

      • SCISCIESCOPUS

        Observation ofψ(3770)→ππJ/ψand Measurement ofΓee[ψ(2S)]

        Adam, N. E.,Alexander, J. P.,Berkelman, K.,Cassel, D. G.,Crede, V.,Duboscq, J. E.,Ecklund, K. M.,Ehrlich, R.,Fields, L.,Galik, R. S.,Gibbons, L.,Gittelman, B.,Gray, R.,Gray, S. W.,Hartill, D. L.,Helts American Physical Society 2006 Physical Review Letters Vol.96 No.8

        <P>We observe signals for the decays psi(3770) --> XJ/psi from data acquired with the CLEO detector operating at the CESR e+ e- collider with square root of s = 3773 MeV. We measure the following branching fractions Beta(psi(3770) --> XJ/psi and significances: (189 +/- 20 +/- 20) x 10(-5) (11.6sigma) for X = pi+ pi-, (80 +/- 25 +/- 16) x 10(-5) (3.4sigma) for X = pi0 pi0, and (87 +/- 33 +/- 22) x 10(-5) (3.5sigma) for X = eta, where the errors are statistical and systematic, respectively. The radiative return process e+ e- --> gamma psi(2S) populates the same event sample and is used to measure Gamma ee[psi(2S)] = (2.54 +/- 0.03 +/- 0.11) keV.</P>

      • Local electronic structure of Mn dopants in ZnO probed by resonant inelastic x-ray scattering

        Chang, G S,Kurmaev, E Z,Jung, S W,Kim, H-J,Yi, G-C,Lee, S-I,Yablonskikh, M V,Pedersen, T M,Moewes, A,Finkelstein, L D IOP Pub 2007 Journal of physics, an Institute of Physics journa Vol.19 No.27

        <P>The electronic structure of Mn dopants in ZnO epitaxial thin films synthesized at different temperatures has been investigated using resonant inelastic x-ray scattering. The resulting Mn L<SUB>2,3</SUB> x-ray emission spectra of Zn<SUB>0.8</SUB>Mn<SUB>0.2</SUB>O (resonantly excited at L<SUB>2</SUB> and L<SUB>3</SUB> absorption edges) reveal different spectral features depending on the growth temperature of the films. The relative integral intensity ratio of Mn L<SUB>2</SUB> to Mn L<SUB>3</SUB> emission lines is greatly suppressed in the case of nonmagnetic Zn<SUB>0.8</SUB>Mn<SUB>0.2</SUB>O grown at 700 °C due to L<SUB>2</SUB>L<SUB>3</SUB>M<SUB>4,5</SUB> Coster–Kronig transitions. The ferromagnetic sample grown at 600 °C exhibits a normal oxide structure. The results suggest that a high growth temperature causes direct Mn–Mn bonds from the segregation of Mn atoms in ZnO. Therefore the disappearance of ferromagnetism in Mn-doped ZnO can be attributed to antiferromagnetic Mn–Mn exchange interactions due to the inhomogeneous local environment around the Mn impurities.</P>

      • Effects of the novel angiotensin II receptor type I antagonist, fimasartan on myocardial ischemia/reperfusion injury

        Han, J.,Park, S.J.,Thu, V.T.,Lee, S.R.,Long, L.T.,Kim, H.K.,Kim, N.,Park, S.W.,Jeon, E.S.,Kim, E.J.,Yoon, C.H.,Cho, G.Y.,Choi, D.J. Elsevier/North-Holland Biomedical Press 2013 INTERNATIONAL JOURNAL OF CARDIOLOGY Vol.168 No.3

        Background: The aim of this study was to investigate the cardioprotective effect of fimasartan, a newly developed angiotensin II receptor type I blocker (ARB), against myocardial ischemia/reperfusion (I/R) injury and to identify the mechanism by which it reduces mitochondrial damage. Methods: Fimasartan was administered intravenously to Sprague-Dawley rats (3mg/kg), cardiomyocytes (50μM), and H9c2 cells (50μM) before ischemia or hypoxia. Myocardial infarction (MI), echocardiograms, DNA fragmentation, terminal deoxynucleotidyl transferase-mediated dUTP in situ nick-end labeling, immunoblotting, oxygen consumption, confocal microscopic appearance, and L-type Ca<SUP>2+</SUP> current (I<SUB>Ca,L</SUB>) were then assessed. Results: Fimasartan pretreatment remarkably reduced the rate of MI and improved cardiac performance well after I/R (n=9/group). Fimasartan also reduced apoptotic cell death both in vivo and in hypoxia/reoxygenation (H/R)-treated H9c2 cells (n=5~8/group). H/R-induced mitochondrial O<SUB>2</SUB><SUP>-</SUP> production and collapse of membrane potential were markedly attenuated in fimasartan-treated cardiomyocytes (n=4~6/group). Additionally, mitochondrial Ca<SUP>2+</SUP> overload during reoxygenation was suppressed by fimasartan (n=4~6/group), and this was found to be possibly related to the inhibition of I<SUB>Ca,L</SUB> and mitochondrial Ca<SUP>2+</SUP> uniporter. Furthermore, fimasartan pretreatment increased phosphorylations of Akt and glycogen synthase kinase-3β (n=5~7/group), decreased pro-apoptotic p53 levels, and increased anti-apoptotic Bcl-2 levels (n=4) during reperfusion. Conclusions: Fimasartan preconditioning has the potential to modulate Bcl-2 and suppress I/R-induced Ca<SUP>2+</SUP> overload by inhibiting I<SUB>Ca,L</SUB> and MCU. These beneficial effects could prevent the mitochondrial dysfunction and apoptosis accompanied by I/R.

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