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      • Factors that Influence Awareness of Breast Cancer Screening among Arab Women in Qatar: Results from a Cross Sectional Survey

        Donnelly, Tam Truong,Al Khater, Al-Hareth,Al-Bader, Salha Bujassoum,Al Kuwari, Mohammed Ghaith,Malik, Mariam,Al-Meer, Nabila,Singh, Rajvir,Fung, Tak Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

        Background: Breast cancer is the most common cancer among women in the State of Qatar. Due to low participation in breast cancer screening (BCS) activities, women in Qatar are often diagnosed with breast cancer at advanced stages of the disease. Findings indicate that low participation rates in BCS activities are significantly related to women's low level of awareness of breast cancer screening. The objectives of this study were to: (1) determine the factors that influence Qatari women's awareness of breast cancer and its screening activities: and (2) to find ways to effectively promote breast cancer screening activities among Arabic speaking women in Qatar. Materials and Methods: A multicenter, cross-sectional quantitative survey of 1,063 (87.5% response rate) female Qatari citizens and non-Qatari Arabic-speaking residents, 35 years of age or older, was conducted in Qatar from March 2011 to July 2011. Outcome measures included participant awareness levels of the most recent national recommended guidelines of BCS, participation rates in BCS activities, and factors related to awareness of BCS activities. Results: While most participants (90.7%) were aware of breast cancer, less than half had awareness of BCS practices (28.9% were aware of breast self-examination and 41.8% of clinical breast exams, while 26.4% knew that mammography was recommended by national screening guidelines. Only 7.6% had knowledge of all three BCS activities). Regarding BCS practice, less than one-third practiced BCS appropriately (13.9% of participants performed breast self-examination (BSE) monthly, 31.3% had a clinical breast exam (CBE) once a year or once every two years, and 26.9% of women 40 years of age or older had a mammogram once every year or two years). Awareness of BCS was significantly related to BCS practice, education level, and receipt of information about breast cancer and/or BCS from a variety of sources, particularly doctors and the media. Conclusions: The low levels of participation rates in BCS among Arab women in this study indicate a strong need to increase awareness of the importance of breast cancer screening in Qatari women. Without this awareness, compliance with the most recent breast cancer screening recommendations in Qatar will remain low. An increased effort to implement mass media and public health campaigns regarding the impact of breast cancer on women's health and the benefits of early detection of breast cancer must be coupled with an enhanced participation of health care providers in delivering this message to Qatar population.

      • Addressing Factors Associated with Arab Women's Socioeconomic Status May Reduce Breast Cancer Mortality: Report from a Well Resourced Middle Eastern Country

        Donnelly, Tam Truong,Al Khater, Al-Hareth,Al Kuwari, Mohamed Ghaith,Al-Bader, Salha Bujassoum,Abdulmalik, Mariam,Al-Meer, Nabila,Singh, Rajvir,Fung, Tak Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

        Differences in socioeconomic status (SES) such as income levels may partly explain why breast cancer screening (BCS) disparities exist in countries where health care services are free or heavily subsidized. However, factors that contribute to such differences in SES among women living in well resourced Middle East countries are not fully understood. This quantitative study investigated factors that influence SES and BCS of Arab women. Understanding of such factors can be useful for the development of effective intervention strategies that aim to increase BCS uptake among Arab women. Using data from a cross-sectional survey among 1,063 Arabic-speaking women in Qatar, age 35+, additional data analysis was performed to determine the relationship between socioeconomic indicators such as income and other factors in relation to BCS activities. This study found that income is determined and influenced by education level, occupation, nationality, years of residence in the country, level of social activity, self-perceived health status, and living area. Financial stress, unemployment, and unfavorable social conditions may impede women's participation in BCS activities in well resourced Middle East countries.

      • Arab Women's Breast Cancer Screening Practices: A Literature Review

        Donnelly, Tam Truong,Al Khater, Al-Hareth,Al-Bader, Salha Bujassoum,Al Kuwari, Mohammed Ghaith,Al-Meer, Nabila,Malik, Mariam,Singh, Rajvir,Jong, Floor Christie-De Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

        Breast cancer incidence and mortality rates are increasing in the Arab world and the involved women are often diagnosed at advanced stages of breast cancer. This literature review explores factors influencing Arab women's breast cancer screening behavior. Searched databases were: Medline, PubMed, Cochrane Database of Systematic Reviews, CINAHL Plus, Google Scholar, Index Medicus for WHO Eastern Mediterranean, and Asian Pacific Journal of Cancer Prevention. Breast cancer screening participation rates are low. Screening programs are opportunistic and relatively new to the region. Knowledge amongst women and health care providers, professional recommendation, socio-demographic factors, cultural traditions, beliefs, religious, social support, accessibility and perceived effectiveness of screening influence screening behavior.

      • KCI등재
      • Making Smart Shirts Smarter : Optimal Electrode Placement for Cardiac Assessment

        M. Donnelly,C. Nugent,D. Finlay,P. McCullagh,N. Black 한국과학기술원 인간친화 복지 로봇 시스템 연구센터 2007 International Journal of Assistive Robotics and Me Vol.8 No.2

          The use of smart textiles within clothing offers the facility to monitor patient vital signs in an unobtrusive manner. In the present study we examine the benefits of integrating electrodes into smart shirts taking into consideration aspects of practical limitations in sensor placement. Three practical scenarios are investigated which restrict possible recording sites to the anterior, lateral, and posterior regions, respectively. A wrapper approach incorporating both nearest neighbor and logistic regression models was adopted to search for and extract relevant features. Two discrimination tasks were investigated; identifying between subjects with evidence of old myocardial infarction, and normal healthy subjects; and identifying between subject suffering from left ventricular hypertrophy and healthy subjects. The results from the study indicate that acceptable classification performance is possible even if recording sites are restricted due to practical constraints.

      • KCI등재
      • Cerebrovascular pressure reactivity monitoring using wavelet analysis in traumatic brain injury patients: A retrospective study

        Liu, Xiuyun,Donnelly, Joseph,Czosnyka, Marek,Aries, Marcel J. H.,Brady, Ken,Cardim, Danilo,Robba, Chiara,Cabeleira, Manuel,Kim, Dong-Joo,Haubrich, Christina,Hutchinson, Peter J.,Smielewski, Peter Public Library of Science 2017 PLoS medicine Vol.14 No.7

        <▼1><P><B>Background</B></P><P>After traumatic brain injury (TBI), the ability of cerebral vessels to appropriately react to changes in arterial blood pressure (pressure reactivity) is impaired, leaving patients vulnerable to cerebral hypo- or hyperperfusion. Although, the traditional pressure reactivity index (PRx) has demonstrated that impaired pressure reactivity is associated with poor patient outcome, PRx is sometimes erratic and may not be reliable in various clinical circumstances. Here, we introduce a more robust transform-based wavelet pressure reactivity index (wPRx) and compare its performance with the widely used traditional PRx across 3 areas: its stability and reliability in time, its ability to give an optimal cerebral perfusion pressure (CPPopt) recommendation, and its relationship with patient outcome.</P><P><B>Methods and findings</B></P><P>Five hundred and fifteen patients with TBI admitted in Addenbrooke’s Hospital, United Kingdom (March 23rd, 2003 through December 9th, 2014), with continuous monitoring of arterial blood pressure (ABP) and intracranial pressure (ICP), were retrospectively analyzed to calculate the traditional PRx and a novel wavelet transform-based wPRx. wPRx was calculated by taking the cosine of the wavelet transform phase-shift between ABP and ICP. A time trend of CPPopt was calculated using an automated curve-fitting method that determined the cerebral perfusion pressure (CPP) at which the pressure reactivity (PRx or wPRx) was most efficient (CPPopt_PRx and CPPopt_wPRx, respectively).</P><P>There was a significantly positive relationship between PRx and wPRx (r = 0.73), and wavelet wPRx was more reliable in time (ratio of between-hour variance to total variance, wPRx 0.957 ± 0.0032 versus PRx and 0.949 ± 0.047 for PRx, <I>p</I> = 0.002). The 2-hour interval standard deviation of wPRx (0.19 ± 0.07) was smaller than that of PRx (0.30 ± 0.13, <I>p</I> < 0.001). wPRx performed better in distinguishing between mortality and survival (the area under the receiver operating characteristic [ROC] curve [AUROC] for wPRx was 0.73 versus 0.66 for PRx, <I>p</I> = 0.003). The mean difference between the patients’ CPP and their CPPopt was related to outcome for both calculation methods. There was a good relationship between the 2 CPPopts (r = 0.814, <I>p</I> < 0.001). CPPopt_wPRx was more stable than CPPopt_PRx (within patient standard deviation 7.05 ± 3.78 versus 8.45 ± 2.90; <I>p</I> < 0.001).</P><P>Key limitations include that this study is a retrospective analysis and only compared wPRx with PRx in the cohort of patients with TBI. Prior prospective validation is required to better assess clinical utility of this approach.</P><P><B>Conclusions</B></P><P>wPRx offers several advantages to the traditional PRx: it is more stable in time, it yields a more consistent CPPopt recommendation, and, importantly, it has a stronger relationship with patient outcome. The clinical utility of wPRx should be explored in prospective studies of critically injured neurological patients.</P></▼1><▼2><P>Using continuous monitoring data in traumatic brain inury patients, Xiuyun Liu and colleagues compare the performance of cerebrovascular pressure reactivity monitoring using wavelet analysis to the pressure reactivity index.</P></▼2><▼3><P><B>Author summary</B></P><P><B>Why was this study done?</B></P><P>The brain is vulnerable to damage from too little (ischemia) or too much (hyperemia) blood flow following traumatic brain injury (TBI).</P><P>A physiological mechanism called cerebral autoregulation (CA) exists to maintain stable blood flow even if cerebral perfusion pressure (CPP) is changing, and an assessment of CA as part of bedside neuro-monitoring of patients with TBI could facilitate individualized treatment.</P><P>A robust method for assessing CA in TBI is not yet available. The traditional measure used, the pressure reactivity index (PRx), provides inherently noisy estimates and

      • BiRSM: bio-inspired resource self-management for all IP-networks

        Balasubramaniam, Sasitharan,Botvich, Dmitri,Mineraud, Julien,Donnelly, William,Agoulmine, Nazim IEEE 2010 IEEE network Vol.24 No.3

        <P>The increased complexity of communication systems has led to new challenges in network management and more specifically, efficient mechanisms to manage communication resources. The vision of autonomic networking aims to overcome these challenges by incorporating self-governance into communication network devices, in order to improve overall efficiency and minimize human intervention. Since biological systems exhibit properties that meet the requirements of self-governance, this article proposes a bio-inspired approach to efficiently manage resources in IP based core networks, called Bio-Inspired Resource Self-Management. The approach aims to provide a holistic solution for ISPs to manage their resources at different timescales as well as automating the interactions with underlying carrier network operators for dynamic resource provisioning. The implemented solution, in a simulator, has shown improved performance compared to traditional approaches.</P>

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