Resistance Development and Recovery of Susceptibility in Relation to Egg Size Change in the Diamondback Moth Treated with Fenvalerate

Xue Dong Chen,Fusao Nakasuii 한국응용곤충학회 2005 한국응용곤충학회 학술대회논문집 Vol.2005 No.05

Efficient production of glutathione using hydrolyzate of banana peel as novel substrate

Xue-Dong Chen,Gong-Yuan Wei,Jun-Li Zhang,Ying-Ying Dong 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.7

The hydrolyzate of banana peels containing abundant fermentable sugars as glucose, xylose, mannose,and arabinose was successfully used as a novel substrate for the efficient production of glutathione by Candida utilis SZU 07-01. Xylose was first selected as the sole carbon source for glutathione production, medium optimization for better cell growth and higher glutathione using response surface methodology consisting of PB design, the steepest ascent experiment and CCD was carried out, and the optimal combination of nutrients was obtained as follows: xylose 20 g/L, (NH_4)-2SO_4 9.59 g/L, KH_2PO_4 3 g/L, L-methionine 5.72 g/L and MgSO_4 0.20 g/L. The maximum dry cell weight and glutathione achieved using the optimized medium were 7.36 g/L and 154.32 mg/L, respectively. Following with the content in this medium, other sugars like glucose, mannose and arabinose were chosen as the sole carbon source and all tested available for glutathione production. Based on these results, the hydrolyzate of banana peels was selected as a novel substrate, and a high DCW of 7.68 g/L and glutathione yield of 111.33 mg/L were obtained with the initial sugar concentration of 20 g/L in the hydrolyzate of banana peels.

Nonsurgical correction of a severe anterior deep overbite accompanied by a gummy smile and posterior scissor bite using a miniscrew-assisted straight-wire technique in an adult high-angle case

Xue-Dong Wang,Jie-Ni Zhang,Da-Wei Liu,Fei-fei Lei,Yan-Heng Zhou 대한치과교정학회 2016 대한치과교정학회지 Vol.46 No.4

In the present report, we describe the successful use of miniscrews to achieve vertical control in combination with the conventional sliding MBT<SUP>TM</SUP> straightwire technique for the treatment of a 26-year-old Chinese woman with a very high mandibular plane angle, deep overbite, retrognathic mandible with backward rotation, prognathic maxilla, and gummy smile. The patient exhibited skeletal Class II malocclusion. Orthodontic miniscrews were placed in the maxillary anterior and posterior segments to provide rigid anchorage and vertical control through intrusion of the incisors and molars. Intrusion and torque control of the maxillary incisors relieved the deep overbite and corrected the gummy smile, while intrusion of the maxillary molars aided in counterclockwise rotation of the mandibular plane, which consequently resulted in an improved facial profile. After 3.5 years of retention, we observed a stable, well-aligned dentition with ideal intercuspation and more harmonious facial contours. Thus, we were able to achieve a satisfactory occlusion, a significantly improved facial profile, and an attractive smile for this patient. The findings from this case suggest that nonsurgical correction using miniscrew anchorage is an effective approach for camouflage treatment of high-angle cases with skeletal Class II malocclusion.

SYNTHESIS OF MINIMUM AVERAGE ROUNDOFF NOISE REALIZATIONS OF PERIODICALLY TIME-VARYING STATE-SPACE DIGITAL FILTERS

Xue Dong Yang,Masayuki Kawamata,Tatsuo Higuchi 대한전자공학회 1992 JTC-CSCC : Joint Technical Conference on Circuits Vol.- No.-

Analysis the role of arabidopsis CKRC6/ASA1 in auxin and cytokinin biosynthesis

Dong-Wei Di,Lei Wu,Pan Luo,Li Zhang,Tian-Zi Zhang,Xue Sun,Shao-Dong Wei,Chen-Wei An,Guang-Qin Guo 한국식물학회 2016 Journal of Plant Biology Vol.59 No.2

The crosstalk between auxin and cytokinin (CK) is important for plant growth and development, although the underlying molecular mechanisms remain unclear. Here, we describe the isolation and characterization of a mutant of Arabidopsis Cytokinin-induced Root Curling 6 (CKRC6), an allele of ANTHRANILATE SYNTHASE ALPHA SUBUNIT 1 (ASA1) that encodes the á-subunit of AS in tryptophan (Trp) biosynthesis. The ckrc6 mutant exhibits root gravitropic defects and insensitivity to both CK and the ethylene precursor 1-aminocyclopropane-1-carboxylicacid (ACC) in primary root growth. These defects can be rescued by exogenous indole-3-acetic acid (IAA) or tryptophan (Trp) supplementation. Furthermore, our results suggest that the ckrc6 mutant has decreased IAA content, differential expression patterns of auxin biosynthesis genes and CK biosynthesis isopentenyl transferase (IPT) genes in comparison to wild type. Collectively, our study shows that auxin controls CK biosynthesis based on that CK sensitivity is altered in most auxin-resistant mutants and that CKs promote auxin biosynthesis but inhibit auxin transport and response. Our results also suggest that CKRC6/ASA1 may be located at an intersection of auxin, CK and ethylene metabolism and/or signaling.

Kinetics of a Cloned Special Ginsenosidase Hydrolyzing 3-O-Glucoside of Multi-Protopanaxadiol-Type Ginsenosides, Named Ginsenosidase Type 3

( Xue Feng Jin ),( Hong Shan Yu ),( Dong Ming Wang ),( Ting Qiang Liu ),( Chun Ying Liu ),( Dong Shan An ),( Wan Taek Im ),( Song Gun Kim ),( Feng Xie Jin ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.3

In this paper, the kinetics of a cloned special glucosidase, named ginsenosidase type III hydrolyzing 3-O-glucoside of multi-protopanaxadiol (PPD)-type ginsenosides, were investigated. The gene (bgpA) encoding this enzyme was cloned from a Terrabacter ginsenosidimutans strain and then expressed in E. coli cells. Ginsenosidase type III was able to hydrolyze 3-O-glucoside of multi-PPD-type ginsenosides. For instance, it was able to hydrolyze the 3- O-β-D-(1→2)-glucopyranosyl of Rb1 to gypenoside XVII, and then to further hydrolyze the 3-O-β-D-glucopyranosyl of gypenoside XVII to gypenoside LXXV. Similarly, the enzyme could hydrolyze the glucopyranosyls linked to the 3-O- position of Rb2, Rc, Rd, Rb3, and Rg3. With a larger enzyme reaction Km value, there was a slower enzyme reaction speed; and the larger the enzyme reaction Vmax value, the faster the enzyme reaction speed was. The Km values from small to large were 3.85 mM for Rc, 4.08 mM for Rb1, 8.85 mM for Rb3, 9.09 mM for Rb2, 9.70 mM for Rg3(S), 11.4 mM for Rd and 12.9 mM for F2; and Vmax value from large to small was 23.2 mM/h for Rc, 16.6 mM/h for Rb1, 14.6 mM/h for Rb3, 14.3 mM/h for Rb2, 1.81mM/h for Rg3(S), 1.40 mM/h for Rd, and 0.41 mM/h for F2. According to the Vmax and Km values of the ginsenosidase type III, the hydrolysis speed of these substrates by the enzyme was Rc>Rb1>Rb3>Rb2>Rg3(S)>Rd>F2 in order.

정부보조금이 연구개발투자에 미치는 영향: 중국 신삼판 기업을 중심으로

장학동 ( Xue Dong Zhang ),강신애 ( Shin Ae Kang ) 한국국제경영학회 2013 國際經營硏究 Vol.34 No.3

본 논문은 정부보조금의 기업 연구개발투자에 대한 영향을 중국 신삼판 시장을 대상으로 분석하였다. 연구방법으로는 연구개발투자의 지속성을 고려하여 자기상관과 이분산성을 통제한 Newey-West 방법을 사용하였다. 연구기간은 2014년에서 2022년까지로 중국 신삼판 시장에 상장된 12월 결산 비금융업체 중 연구개발집약도가 중위값 이상인 5개 산업을 대상으로 분석하였다. 분석결과 첫째, 정부보조금은 연구개발집약도에 유의한 양(+)의 영향을 미쳤으며, 이러한 관계는 최대주주지분율의 대소, 국유기업 여부나 정치적 연계 유무에 관계없이 유의한 양(+)의 관계가 나타나 정부보조금이 초기 창업기업의 재무제약을 약화시키고 기술혁신활동에 정(+)의 영향을 미침을 확인하였다. 둘째, 정부보조금은 연구개발투자효율성에 유의한 음(-)의 영향을 미쳤으며, 최대주주지분율의 대소, 국유기업 유무나 정치적 연계 유무에 관계없이 유의한 음(-)의 관계가 나타났다. 연구개발 지출과 효율성이 연계되어 있어 중소벤처기업들의 거래소인 신삼판에서 정부보조금을 통해 연구개발 지출을 일정수준까지 증가시키는데 이용할 수 있다. 그러나 정부보조금을 받기 위해 기업은 정부의 요구에 맞는 첨단기술투자를 할 유인 등 기업의 연구개발투자에 따른 효율성이 크게 감소된다. 따라서 이러한 연구결과는 정부보조금이 연구개발투자 지출과 연구개발 자원의 유효 활용 정도인 연구개발투자효율성에 대한 영향이 다르므로 기업이 정부보조금을 통한 연구개발투자 지출 증가 뿐 아니라 효율성을 동시에 증가시킬 수 있는 방향으로 정부보조금이 지원되어야 함을 시사한다. This paper analyzed the impact of government subsidies on corporate R&D investment in the Chinese New Third Board market. The Newey-West method was used to control for autocorrelation and heteroscedasticity, considering the sustainability of R&D investment. The research period was from 2014 to 2022, and the analysis was conducted on five industries with R&D intensity above the median among non-financial companies with December settlement listed on the Chinese New Third Board. The analysis results showed that government subsidies had a significant positive impact on R&D intensity, regardless of the size of the largest shareholder’s stake, state ownership, or political connections. It was confirmed that government subsidies weaken financial constraints for start-up companies and have a positive impact on technological innovation activities. However, government subsidies had a significant negative impact on R&D investment efficiency, and this significant negative relationship was found regardless of the size of the largest shareholder’s stake, state ownership, or political connections. As R&D expenditure and efficiency are interrelated, government subsidies can be used to increase R&D expenditure to a certain level for small and medium-sized venture companies in the New Third Board market. However, to receive government subsidies, companies’ R&D investment efficiency decreases significantly due to incentives for advanced technology investment that meets government requirements. Therefore, these research results indicate that government subsidies should be supported in a direction that can increase not only R&D investment expenditure but also efficiency, as government subsidies have different effects on R&D investment efficiency, which is the degree of effective utilization of R&D investment expenditure and resources by companies.

중국 아파트 거주자를 대상으로 한 스마트 주택 요구도 분석

동설(Dong Xue),김미정(Kim, Mi Jeong),조명은(Cho, Myung Eun) 한국주거학회 2016 한국주거학회 논문집 Vol.27 No.6

Although smart homes have been much developed in China, smart homes has been mainly towards the adoption of new technologies. There is little development of smart homes to consider and meet residents’ needs in China. This study investigated residents’ living in apartments in China using a questionnaire to identify their demands on smart homes. Through the survey, this study analyzed residents’ space use patterns, daily living patterns etc. according to their ages. The results implied that there are significant differences in the use of spaces and demands on daily living within apartments. The results of this study should be considered for the development of smart homes in future. For example, it might be easier for people in the 20’s to adopt Internet of Things (IoT) and environmental control systems compared to other age groups because most of them in the 20’s use smart phones effectively without difficulties. In case of people in their 50’s who stay home more times for taking a rest and eating meals compared to other age groups, smart technologies should be applied to support their health care and works in housings. This research emphasizing residents’ experiences could be basis for the development of smart homes in China.

Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri

Jin-Dong Zhong,Xue-Wei Zhao,Xuan-Qin Chen,Hong-Mei Li,Chin-Ho Chen,Xue-Shan Xia,Rong-Tao Li 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.6

Two new ursane-type triterpenoid saponins,bodiniosides M (1) and N (2), along with three knownsaponins, oblonganosides I (3), pseudobuxussaponin B (4)and bodinioside A (5), were isolated from the aerial partsof Elsholtzia bodinieri. The structures of compounds 1 and2 were characterized by spectroscopic data as well as acidhydrolysis and GC analysis as 3-O-b-D-xylopyranosyl-19ahydroxy-23-acetoxy-urs-12(13)-en-28-oic acid 28-O-a-Lrhamnopyranosyl-(1-2)-b-D-glucopyranoside and 3-O-b-Dglucopyranosyl-2a,19a-dihydroxy-urs-12(13)-en-28,20blactone. Compounds 1 and 5 exhibited potent anti-HCVactivities in vitro with a selective index of 6.53 and 4.41,respectively.

Hot Forging Process Design Optimization Based on Approximate Model and FEM Simulation

Chen, Xue Wen,Jung, Dong Won,Sun, Ai Xue Trans Tech Publications, Ltd. 2008 Materials science forum Vol.575 No.-

<P>Technology and die design are very important in the development of forging products due to its great influence on the quality, cost and manufacturing efficiency of the final products as well as the life of the forging die. In the environment of the severe competition, how to improve the quality of forging technology and die design, to reduce the product cost and ultimately to enhance competitiveness of the forging factory are the problems that forging technology and die designer have to solve. In order to improve the quality of forging technology and die design, a design optimization method based on approximate model (response surface model) and FEM technique for hot forging process is proposed in this paper. During design optimization process, finite element analysis is incorporated to calculate the objective function and check the design alternatives. Design of experiment (DOE) method is used to collect sample points and calculate the polynomial coefficients of response surface model, and approximate model is used to calculate the optimum search direction. Finally, a case study is conducted for a gear workpiece hot forging process. The objective function is the degree of uniformity of equivalent-strain, which can be defined as mean square deviation of the equivalent-strain in each element and the average equivalent-strain of all elements, and the design parameters are the initial H0/D0 ratio of billet and the key dimensions of the die. Then the design optimization mathematical model is established. The result shows that the objective function value is dropped from 0.7914 and converges at 0.4843 within 17 iterations, the optimal design parameters are obtained.</P>