자기 공명 영상을 이용한 뇌척수액 순환의 역학 분석

김동석,치중언,윤펑호,김동익,박승우 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.5

세파졸린의 산-염기의 거동

이동선,김수현,이윤중 서울여자대학교 자연과학연구소 1990 자연과학연구논문집 Vol.1 No.-

항생물질 cefazolin(CZH)의 산-염기 해리반응에 관해 실험하여 다음과 같은 결론을 얻었다. 1. 전위차법으로 25℃에서 측정한 CZH의 pKa 값은 3.78(±0.05) 이었다. 전도도법으로 측정한 경우 pKa=3.75였으며, [CZNa]/[CZH] = 1.00의 완충용액으로 측정하였을 때에는 pKa = 3.41이었다. 2. CZNa+CZH 혼합용액의 전기 전도도는 [CZNa] 농도가 증가될수록 공통이온외 영향으로 약간씩 감소되었다. 3. CZH의 용해도는 92.8mg/100mL이고, 해리도는 0.4650으로 산출되었다. 4. CZH의 pKa 값은 5~50℃ 범위에서 커다란 변화가 없었다. 5. CZH 산해리반응을 열역학적으로 고찰할 때, ΔG°=+19.995kJ/mol이었다. 따라서 CZH 외 난용성을 증명할 수 있었다. 6. 산-염기 분율조성을 고찰한 결과 pH<3.78의 수용액중에서는 산성형 CZH가 주된 화학종이고 pH>3.78인 용액중에서는 염기형인 CZ^(-)가 주된 화학종임을 알았다. 7. 5% 포도당 주사액중에서는 CZH가, Hartman용액중에서는 CZ^(-)가 주된 화학종이며, 생리식염 주사액중에서는 두 화학종이 비숫하게 분포하였다. 8. 생체액중에서의 CZH거동을 고찰한 결과 동맥혈, 정맥혈, 안방수, 누액, 십이지장, 회장, 소장 등에서는 99%이상 CZ^(-)형태로 분포하고, 위장에서는 약 99%가 CZH형태로 분포하리라 추정되었다. 9. UV 및 IR 흡광특성은 CZNa가 CZH에 비하여 장파장 이동을 나타내었다. The purpose of this study was to determine the acid dissociation constant of cefazolin antibiotics potentiometrically and conductometricaliy, and to identify the principal species in parenteral infusions and body fluids with different pH values. The pKa of cefazolin was 3.78(±0.05) at 25℃, and the pKa value of cefazolin was almost constant at temperature range of 5~50℃. As the concentration of basic form in the mixture of cefazolin(CZH) and cefazolin sodium(CZNa) increased the conductance decreased still further because of the common ion effect. The computed solubility of CZH was 92.8mg/100mL, the fractrion of dissociation a was found 0.4650. The low solubility was demonstrated thermodynamically. The Gibb's energy change for the dissociation was +19.995kJ/mol, reaction is disfavored. The acidic species(CZH) was the predominant form at pH<3.78, the basic species(CZ^(-)) was the principal form at pH>3.78. The results of pH measurement it was assumed that CZH was major in 5% dextrose inj., CZ^(-) in Hartman's solution, and CZH and CZ^(-) existed almost equally in saline solution. It was also assumed that the major form was basic in aqueous humor, blood venous, duodenum, ileum distal, lacrimal fluids, and intestine microsurface, while acidic in the stomch. UV and IR spectra of the basic form, CZ was showed bathochromic shift.

Amiodarone 投與에 의한 肝의 燐脂質症

김동훈,장금미,서인수,손태중 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.1

편마비 환자의 정상측과 마비측의 비복근 운동점에서의 근육 두께 차이

김동건,도현경,김현동,황지선,정규영,정호중 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

Objective : To investigate any difference of muscle thickness in the motor points of the gastrocnemius between the paretic and non-paretic legs in hemiplegics. Method : Ultrasonography was used to assess in vivo the gastrocnemius muscle thickness at the motor points in the paretic and non-paretic legs of twenty-four patients with stroke. Results : Muscle thickness at the motor points were reduced in the paretic legs compared to the non-paretic legs (p<0.05). There was no correlation between muscle thickness and duration of hemiplegia, site of hemiplegia. However, it did not take regular pattern of the muscular atrophy in the paretic legs. Conclusion : The gastrocnemius muscle of the paretic leg had smaller thickness compared with the non-paretic leg. The present results indicate that paresis in hemiplegics may affect the accuracy of intramuscular injection of botulinum toxin A. Therefore, we recommend ultrasonography for visually controlled, anatomically precise injection of botulinum toxins.

최근 10년간 발생한 신손상 분석

최동은, 김원태, 김용준, 윤석중, 이상철, 김원재 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

연구목적: 신손상은 보통 복부외상 환자의 10% 정도에서 발생하며 비뇨기계에서 발생하는 손상 중 가장 높은 빈도를 차지하고 있다. 신손상 치료의 궁극적인 목표가 환자의 생명을 구하는 것이고, 가능 하면 신조직을 최대한 보존하면서도 합병증은 최소화하여야 하므로 정확하게 평가된 진단을 내려, 혈류 역학적으로 안정된 경우 보존적 요법을 시행하는 빈도는 증가하고 있다. 본 연구에서는 10년간의 신손 상을 분석하여 손상의 원인, 정도, 치료 방법 등을 알아보고자 하였다. 대상및방법: 2000년 2월부터 2010년 6월까지 본원 응급실에 방문하여 신손상으로 진단된 59명의 환 자들을 후향적으로 분석하였다. 결과: 환자의 성별은 남자가 39례 (66.1%)였고, 여자가 20례 (33.9%)였다. 신손상의 원인은 교통 사고가 37례 (62.7%)였고, 낙상이 7례 (11.9%), 외상이 12례 (20.3%), 자상이 1례 (1.7%), 원 인미상이 2례 (3.4% )였다. 손상의 정도는 I 등급이 11례 (18.6%), II 등급이 10례 (16.9%), III 등급이 20례 (33.9%), IV 등급이 10례 (16.9%), V 등급이 8례 (13.6%)였다. 신손상 환자의 치료 는 대증치료가 46례 (77.9%)였고, 신절제술이 5례 (8.5%), 신혈관색전술이 5례 (8,5%), 그외 다른 치료들이 3례 (5.1%)였다. 결론: 신손상의 원인은 교통사고와 외상 등이 가장 많은 비중을 차지했으며, 3 등급의 손상이 가장 많 았고, 치료는 대증요법이 주를 이루었지만, 점차 신혈관색전술이 늘어나고 있다. 앞으로 지역단위로의 추가적인 연구가 필요할 것으로 생각된다.

헬름홀츠 코일을 이용한 강자성체의 와전류검사

성제중,서동만,신용훈,엄태건,서동섭 한국비파괴검사학회 2003 학술대회 논문집 Vol.- No.1

Ferromagnetic material like the steel tubes can easily distort eddy current testing signal due to increased magnetic permeability for defects. Because magnetic field of the test probe is affected in an inconsistent way when the material under the testing has permeability. This permeability effect can be reduced by magnetic saturation. In this paper eddy current testing system was developed to detect flaws on the steel tubes. Magnetic saturation probe with helmholtz coil was designed for saturation and inspection of the steel tubes. When using the designed test probe, the relationship between flaw signals and noises was obviously discriminated. Additionally, a high pass filter was included in the eddy current board to minimize noises due to DC magnetic field.

24주간 추적하는 임상 연구에서 한국인 남자 알코올 의존 환자의 비재발률

강철중,김성곤,남궁기,조동환,이병욱,최인근,최용성,박성봉,제영묘,김현경,김성연 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.1

Objetives : In order to provide useful data tbr the further clinical studies with Korean alcohol-dependent patients, enrollment and non-relapse rates were investigated while alcohol-dependent patients wcre followed up for 24 weeks. Methods : The subjects of this study were alcohol-dependent male patients who, for the first time, visited a hospital among 3 groups of hospitals, University Hospital, General Hospital or Mental Hospital, or those who needed to be followed up after discharge from those hospitals. After assigning 12 subjects to each hospital, we investigated enrollment and non-relapse rates while cognitive-behavioral therapy and pharmacotherapy were provided. Results : 1) Forty-eight patients were enrolled and the rate of enrollment was 36.4%. The enrollment rate in the University Hospital group was 52.1%, in the General Hospital group 50.0%. and in the Mental Hospital group 10.4%. 2) In 48 patients, non-relapse rate was 27.1% at 12 week and 18.8% at 24 weeks after starting follow-up. It was 24.4% and 20.0% at 12 and 24 weeks, repectively, in the University Hospital group while the General Hospital group showed 33.3% and 16.7%, respectively, and the Mental Hospital Group showed 20.0% at both 12 and 24 weeks. Conclusion : These results provide important data for further clinical studies of Korean alcohol-dependent patients.

한국인의 치아우식 조절에 관한 연구 : Ⅲ. 만경강 유역 주민의 뇨중 불소농도, 반상치 지수에 관한 연구 STUDY ON THE RELATION BETWEEN THE URINARY FLUORIDE CONCENTRATIONAND THE FLUOROSIS INDEX OF RESIDENTS IN MANKYUNG RIVER VALLEY

정동균,정태영,이종흔,김중수,오귀옥,이효재 대한구강생물학회 1980 International Journal of Oral Biology Vol.4 No.1

This experiment was conducted to elucidate the relation between the urinary fluoride concentration and the fluorosis index of residents in Mankyung River valley, especially in 3 areas (Yookang-ri, Koje·Yoochun, Shinbok·Yongkang) with high fluoride concentration in drinking water. The urinary fluoride concentration was measured by fluoride ion electrode, and dental fluorosis was surveyed and analysed by Dean and McKay's and Horowitz's method. 1. There was no reletionship between the urinary fluoride concentration and age. 2. 11-20 years age groups has revealed the highest fluofosis index. In this group : 3. There showed a parallel relationship between the fluorosis index and the urinary fluoride concentration. 4. DMF rates of residents in Yookang-ri, Koje and Shinbok are 59.2, 48.4 and 47.1%, respectively. 5. There showed a parallel relationship between the years of residence within 8 years after birth and the fluorosis index.

Chloroprene rubber latex의 MMA graft 중합

김동민,이봉재,한병학,김형중 公州大學校 工學硏究院 生産技術硏究所 2003 論文集 Vol.11 No.-

The graft polymerization of chloroprene rubber(CR) latex with methyl methacrylate(MMA) was carried out by using a water soluble radical initiator, potassium persulfate(KPS). The reaction was executed with different solid content of CR latex and weight ratio of MMA to initiator at the same temperature, 80℃. The identification and characterization of MMA grafted CR latex were achieved with FT-IR spectrum using an absorption band at wave number 1732㎝^(-1) assigned for carbonyl(C=O) group of MMA. After the graft polymerizations, average particle sizes of reactants were measured. In addition adhesion strengths were tested with SBR and cotton denim using 180^(o) peel test method. Consequently, it has been found that the direct graft polymerization of MMA to CR latex was successful achieved and affected by amount of MMA and weight ration of initiator to monomer, and solid content of CR latex significantly.

미국 FBI-HQ 견학 보고

김동욱,이중 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-