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      • KCI등재

        Lightweight Printed Dipole Antenna Array With 3×2 Beamforming Network for Wide UAV Communication Coverage

        Dong‑Geun Seo,Jeong‑Soo Park,Gun ‑Ki Lee,Wang‑Sang Lee 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.4

        In this paper, a lightweight printed dipole antenna array with 3×2 beamforming network for wide unmanned aerial vehicle (UAV) communication coverage is presented. The proposed antenna consists of an upper substrate, a lower substrate, and two supports with a microstrip feeding. The upper substrate has a two-element printed dipole antenna array, and the lower substrate includes a beamforming feeding circuit and a ground plane as a refector of the proposed antenna array for gain improvement. For wide beam coverage, the proposed feeding network consists of three RF switches, one Wilkinson power divider, and one 90° hybrid coupler, and generates the wide beam using one broadside beam and two end-fre beams. Measured impedance bandwidth, peak gain, and half-power beamwidth (HPBW) of the proposed array operated from 5.03 to 5.15 GHz are approximately 2 GHz, 4.3 dBi, and 155°, respectively.

      • 동종 조혈모세포이식 후 발생한 크립토콕쿠스 척추염 1예

        고윤호,임동준,이성수,조유경,이동건,최정현,김유진,민창기,김동욱,박정미,김춘추,신완식 대한감염학회 2001 감염 Vol.33 No.4

        Skeletal cryptococcosis is an uncommon infection. Cryptococcus is a common cause of meningitis and infects 7∼10% of patients with AIDS. As well as AIDS, the infection may be seen in association with leukemia, lymphoma, Hodgkin's disease, sarcoidosis, tuberculosis and diabetes, also in patients on steroid medication. But there is no case report of skeletal cryptococcosis following allogeneic hematopoietic stem cell transplantation. A 40-year-old woman was admitted to the hospital because of low back pain. She had chronic myelogenous leukemia for 2 years and underwent allogeneic hematopoietic stem cell transplantation 8 months ago. She have been treated with steroid and cyclosporine orally because of chronic graft versus host disease. On examination she was afebrile and had posterior lower lumbar tenderness. But, she had no reduced strength of low extremities. Open biopsy was underwent. Histology demonstrated budding, round-to-oval, refractile yeast-like organisms within debris. The results of a lumbar puncture were unremarkable and cerebrospinal fluid culture failed to grow bacteria and yeast. The patient was treated with amphotericin B (1 gram) and AmBisome□ (2.8 gram) over 6 weeks. Three months after cessation of therapy, the patient was doing well.(Korean J Infect Dis 33:298∼301, 2001)

      • 영도구 자원봉사활동 활성화 방안 연구

        류황건,김수정,이동은 고신대학교 영도발전연구소 2003 영도연구 Vol.5 No.-

        The importance of volunteering service activity has greatly come to the front as a value to comprehensive politics, economy, society and culture and supplement. On 'the year of world volunteers', the organized 'Korea Commission' is in active service, and ahead of the 2002 Korean and Japanese World Cup, many efforts are being made for enacting 'the Support Law of Volunteering Service Activity' while the boom of volunteering activity is formed. The purpose of this study was to improve the volunteer activities in Yeongdo-Gu, Busan. The surveys were conducted by nongovernment organizations, religious organizations, elementary schools, middle schools, high schools, universities and individual volunteers. The statistical analysis was used descriptive statistics by using SAS 10.2 program. The results of these surveys are summarized as follows: First,a membership of Yeongdo-Gu Volunteering Service Center established in 1997 is 1,277(man 634, woman 643) and its roles are to network with welfare facilities, to enhance the participating rate of citizens, and to educate volunteers and so forth. Second, as a result of individual volunteers survey, the subject of analysis were a total 64 cases of 45(70.3%) male and 19(29.7) female, their occupations are students 32(50.8%), housekeeper 13(20.6%). Third, Volunteers were participating in various fields of volunteer including social welfare, environment, transportation, health, culture and art. Thus operation plans to activate Yeongdo-Gu Volunteer activities are proposed as follows. First, it is necessary for assurance of volunteering resource in community and volunteering network construction for efficiency management. Second, it is also necessary for assurance of training program for volunteer.

      • 편마비 환자의 정상측과 마비측의 비복근 운동점에서의 근육 두께 차이

        김동건,도현경,김현동,황지선,정규영,정호중 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

        Objective : To investigate any difference of muscle thickness in the motor points of the gastrocnemius between the paretic and non-paretic legs in hemiplegics. Method : Ultrasonography was used to assess in vivo the gastrocnemius muscle thickness at the motor points in the paretic and non-paretic legs of twenty-four patients with stroke. Results : Muscle thickness at the motor points were reduced in the paretic legs compared to the non-paretic legs (p<0.05). There was no correlation between muscle thickness and duration of hemiplegia, site of hemiplegia. However, it did not take regular pattern of the muscular atrophy in the paretic legs. Conclusion : The gastrocnemius muscle of the paretic leg had smaller thickness compared with the non-paretic leg. The present results indicate that paresis in hemiplegics may affect the accuracy of intramuscular injection of botulinum toxin A. Therefore, we recommend ultrasonography for visually controlled, anatomically precise injection of botulinum toxins.

      • KCI등재후보

        항생제의 약동학/약역학 : 기본 개념 및 임상응용

        이동건,신현호 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

        Pharmacokinetics (PK) of antibiotics can be considered as the absorption, distribution and elimination of drug. Pharmacodynamics (PD) is the relationship between concentration of drug and the antimicrobial effect. Time course of antibiotic activity is a reflection of the interrelationship between PK and PD. Over the past decades, considerable data have been derived from in vitro, in vivo models and infected patients. The time course activity characteristics of concentration effect and postantibiotic effects, determine the typical patterns of antibiotic activity according to the PD classification. Furthermore, the pattern of antibiotic activity over time is an important determinant of optimal dosage regimens. This review will focus on general concepts and the applications of PK/PD to antibiotic therapy.

      • 균일가열법으로 제조한 반용융 A390합금의 미세조직 및 성형성

        임수근,윤병은,장동훈,엄정필,김득규 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

        Microstructure of hypereutectic Al-17wt.% Si alloy, fabricated by mechanical stirring and by reheating at semi-solid state, was investigated by optical microscope. Flow behavior semi-solid metal also was investigated at diffentent mould temperatures 280℃, 290℃ and 300℃ . Size of silicon particles were increased over 100㎛ durig solidification as a result of stirring. It is considered as microstructural coarsening by bonding between neighbouring primary silicon particles during stirring of slurry. In case of reheating at semi-state, however, primary silicon particle was not increased at size of 40㎛ and nearly spherical aluminum solde particle also was improved when solid fraction was 0.7 at mould temperature of 300℃ than other conditions.

      • KCI등재후보

        호중구 감소성 발열환자에게 경험적으로 투여한 Teicoplanin의 효과

        이동건,임동석,최수미,박선희,유진홍,최정현,민우성,신완식,김춘추 대한감염학회 2004 감염과 화학요법 Vol.36 No.2

        목적 : 호중구감소성 발열 환자에게 경험적으로 teicoplanin을 투여할 때의 효과를 알아보고자 전향적 연구를 시행하였다. 방법 : 2003년 7월부터 12월까지 가톨릭조혈모세포이식센터에 입원하여 항암치료 혹은 조혈모세포이식을 시행하고 호중구감소성 발열이 있는 환자 중 초기 항균요법에 반응이 없어 경험적 teicoplanin 투여가 필요한 49명을 대상으로 A, B 제조회사에서 제공한 teicoplanin을 무작위로 어느 한 쪽 치료군에 배정하여 투여하였다. 용량은 첫날 400㎎ 부하용량을 정맥내 bolus로 투여하고 매 24시간마다 200㎎ 유지용량을 투여하였다. 결과 : A군 27명, B군 22명이 연구에 참여하였고 대부분의 환자가 신독성이 있는 약제를 병용하고 있었다. A군 8명, B군 7명에서 그람양성균이 동정되었고, teicoplanin에 대한 내성률은 A군 22.2%, B군 28.6%로 유의한 차이는 없었다(P=1.00; 0.61<95%CI<1.95). 미생물학적 확인 감염이 있었던 환자 중 평균 53.3%에서 완치 혹은 개선의 반응이 있었고 양 군간 유의한 차이는 없었다(A군 4명 [50.0%], B군 4명 [57.1%], P=1.00; 0.29<95%CI<2.60). 미생물학적 제거율은 평균 62.5% (A군 55.6%, B군 71.4%)이었고 그 외 미생물학적 효과는 A군에서 제거 후 재발 2명(22.2%), 내성 2명(22.2%)이었고 B군에서 각각 0명(0.0%), 2명(28.6%)이었으며 양 군간 유의한 차이는 없었다(P=0.28). 발열기간(P=0.89), teicoplanin 사용기간(P=0.47) 및 전체적인 사망률(P=1.00; 0.78<95%CI<1.24)도 양 군간 유의한 차이는 없었다. 이상반응 중 신독성은 16.3% (A군 18.5%, B군 13.6%)에서 나타났고 양 군에 차이는 없었으며(P=0.72; 0.39<95%CI<3.51), 신기능 이상과 관련있는 약제를 적어도 2개 이상 병용하고 있었다. 피부발진은 A군에서 1명, B군에서 3명 발생하였다(P=0.31; 0.93<95%CI<1.34). 결론 : 호중구감소성 발열환자에게 teicoplanin을 투여하였을 때 임상적 반응률은 평균 53.3%(A군 50.5%, B군 57.1%), 미생물학적 제거율은 평균 62.5%(A군 55.6%, B군 71.4%)이었고 두 제조회사간 차이가 없었고 이상반응도 양 군간 차이가 없었다. 앞으로 국내 호중구감소증 환자에서의 teicoplanin의 적정 용량, 용법 등을 알기 위한 집단 약동학 등의 연구를 시행할 예정이다. Background : This study was done to elucidate the efficacy of teicoplanin as the empirical treatment for febrile neutropenia. Methods : Patients were randomized to two groups according to pharmaceutical company (company A or B). Total of 49 patients (A, 27; B, 22) with neutropenic fever were studied prospectively for 6 months (Jul. 2003-Dec. 2003). Patients received 400 mg i.v. once, then 200 mg i.v. once daily. Results : Groups were matched for all demographic variables. Most of the patients were concurrently receiving nephrotoxic drugs. Gram positive microorganisms were isolated in 8 patients for A and 7 patients for B. Resistance rate against teicoplanin was 22.2% in A and 28.6% in B (P=1.0; 0.61 < 95% confidence interval [Cl] < 1.95). Among the patients with microbiologically documented infection, clinical cure or improvement was seen in 4 (50%) of 8 patients for A and 4 (57.1%) of 7 patients for B (P=1.00; 0.29 <95%CI <2.60). Bacteriologic efficacy was assessed as follows; elimination in 5 (55.6%), elimination with relapse in 2 (22.2%), resistance in 2 (22.2%) out of 9 gram-positive bacteria for A and 5 (51.4%), 0 (0.0%), 2 (28.6%) out of 7 bacteria for B, respectively (P=Q.28). There were no significant differences in duration of fever, duration of use of teicoplanin, and overall mortality. The incidence of nephrotoxicity and ototoxicity was not significant. Conclusion : For using teicoplanin as the empirical therapy for febrile neutropenia, the rate of clinical, microbiological response, and nephrotoxicity was 53.3%, 62.5%, and 16.3% respectively with no significant differences between the 2 preparations of teicoplanin. Supplementary evaluation on the adequate dose and duration of teicoplanin may be required.

      • SCOPUSKCI등재

        Aspergillus niger로 부터 α-glucosidase 발현억제 형질전환체의 분리

        이동건,이진영,서영배 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4

        We have already cloned an extracellular α-glucosidase gene from Aspergillus niger with oligonucleotide probe synthesized on the basis of the peptide sequences determined previously. The DNA sequence revealed an open reading frame of 895 amino acids split by three introns. We are attempting to construct an A. niger strain deficient in the α-glucosidase enzyme activity, which would be useful for the glucoamylase production without contamination by the industrially undesirable α-glucosidase. For destruction of the α-glucosidase gene, we try to make transformations. A cloned partial α-glucosidase gene was introduced into Aspergillus niger, and transformants with suppressed α-glucosidase activity were isolated. The transformants were cultured on YPD medium which contained Hygromycin B at 30℃. The activity of α-glucosidase of the suppressed transformants was compared to that of wild type activity. As shown by southern-hybridization, we detected that the transformant was a heterocaryon.

      • 피부 두겹 집기법에 의한 한국여자의 연대별 체지방량 측정

        선우재근,심동원 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

        We measured the body fat in 135 female aged between 13 and 65 who are the members of sports max fitness club. The body fat was measured in Back side of arm by Means of Skin bold Method. The results are as follows: The rate of change in body fat according to age. The mean value of body fat was 14.3±3.19㎜ (24.9±3.23%) in the female subjects in her teens. Ageing to adult increased the body fat content to 25.7±5.78㎜. However, ageing over 60 was associated with a decrease in body fat content (23.7±3.05㎜, 39.4±2.37%) (fig 1, 2)

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