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      • KCI등재

        Effects of Quenching Methods and Aging Processes on the Crushing Properties and Microstructure of Al–Zn–Mg Alloy Thin-Walled Square Extrusions

        Hui Guo,Jin Zhang,Cheng Wang,Yun‑lai Deng 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8

        In this study, the effects of different (online quenching and offline quenching) quenching methods and aging processes (T6and T73) on the crashworthiness and microstructural evolution of three Al–Zn–Mg alloys (G1–G3) were studied by conductingtensile test and axial compression tests at room temperature, combined with optical metallography, electron back scattereddiffraction, and transmission electron microscopy microstructural observations. The obtained results revealed that thecrushing properties of three different Al–Zn–Mg alloys subjected to different quenching methods and aging processes weresignificantly different. Their crushing energy absorption of are ranked as follows: G1 > G3 > G2. The highest total energyabsorption gap (between T6 and T73) is the G1 alloy, and the lowest one is the G3 alloy. The largest total energy absorptiongap between the two quenching methods is the G3 alloy, and the smallest one is the G1 alloy. The G2 alloy with the largesttotal amount of Zn + Mg has the highest number density of matrix precipitates, the largest precipitate gap (between T6 andT73) and the smallest precipitate gap between the two quenching methods. The G3 alloy with the largest Zn/Mg ratio hasthe smallest number density of matrix precipitates, the minimum precipitation gap (between T6 and T73) and the maximumprecipitation gap between the two quenching methods. The G1 alloy with the lowest Zn/Mg ratio has the smallest size ofgrain boundary precipitates and PFZ width, while their largest values are obtained for the G3 alloy with the maximum Zn/Mg ratio. As a crushing resistant structural material, the crushing properties is improved without reducing the strength. Theratio of Zn/Mg should be controlled within the range of 4.57–6.15, while the total amount of Zn + Mg should be controlledwithin the range of 6.18–7.01.

      • KCI등재후보
      • Comparative Serum Proteomic Analysis of Serum Diagnosis Proteins of Colorectal Cancer Based on Magnetic Bead Separation and MALDI-TOF Mass Spectrometry

        Deng, Bao-Guo,Yao, Jin-Hua,Liu, Qing-Yin,Feng, Xian-Jun,Liu, Dong,Zhao, Li,Tu, Bin,Yang, Fan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

        Background: At present, the diagnosis of colorectal cancer (CRC) requires a colorectal biopsy which is an invasive procedure. We undertook this pilot study to develop an alternative method and potential new biomarkers for diagnosis, and validated a set of well-integrated tools called ClinProt to investigate the serum peptidome in CRC patients. Methods: Fasting blood samples from 67 patients diagnosed with CRC by histological diagnosis, 55 patients diagnosed with colorectal adenoma by biopsy, and 65 healthy volunteers were collected. Division was into a model construction group and an external validation group randomly. The present work focused on serum proteomic analysis of model construction group by ClinProt Kit combined with mass spectrometry. This approach allowed construction of a peptide pattern able to differentiate the studied populations. An external validation group was used to verify the diagnostic capability of the peptidome pattern blindly. An immunoassay method was used to determine serum CEA of CRC and controls. Results: The results showed 59 differential peptide peaks in CRC, colorectal adenoma and health volunteers. A genetic algorithm was used to set up the classification models. Four of the identified peaks at m/z 797, 810, 4078 and 5343 were used to construct peptidome patterns, achieving an accuracy of 100% (> CEA, P<0.05). Furthermore, the peptidome patterns could differentiate the validation group with high accuracy close to 100%. Conclusions: Our results showed that proteomic analysis of serum with MALDI-TOF MS is a fast and reproducible approach, which may provide a novel approach to screening for CRC.

      • SCOPUSKCI등재

        Generic Constructions for Strong Designated Verifier Signature

        Feng, Deng-Guo,Xu, Jing,Chen, Wei-Dong Korea Information Processing Society 2011 Journal of information processing systems Vol.7 No.1

        A designated verifier signature is a special type of digital signature, which convinces a designated verifier that she has signed a message in such a way that the designated verifier cannot transfer the signature to a third party. A strong designated verifier signature scheme enhances the privacy of the signer such that no one but the designated verifier can verify the signer's signatures. In this paper we present two generic frame works for constructing strong designated verifier signature schemes from any secure ring signature scheme and any deniable one-pass authenticated key exchange protocol, respectively. Compared with similar protocols, the instantiations of our construction achieve improved efficiency.

      • KCI등재

        Silencing downstream of receptor kinase gene (drk) impairs larval-pupal ecdysis in Leptinotarsa decemlineata (Say)

        Pan Deng,Jun-Li Du,Li-Li Mu,Kai-Yun Fu,Wen-Chao Guo,Guo-Qing Li 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.1

        In insects, an insulin-like peptide (ILP) triggers the formation of the insulin receptor (InR)/the insulin receptor substrate Chico complex. The complex then recruits downstream of receptor kinase (Drk) and phosphatidylinositol-3-kinase (PI3K) to initiate two signaling branches, i.e., Drk-mitogen-activated protein kinase (MAPK) and Pi3K-protein kinase B subdivisions. Previous findings reveal that RNA interference (RNAi) of LdILP2 or Ldchico, rather than Ldpi3k92E, impairs larval-pupal and pupal-adult molting in the Colorado potato beetle Leptinotarsa decemlineata. It is accordingly hypothesized that the Drk-MAPK branch regulates larval metamorphosis. In the present paper, we first found that silencing LdILP2, Ldchico or Ldpi3k92E did not decrease the expression level of Lddrk, indicating other receptor tyrosine kinases’ signaling except insulin pathway is not affected in the RNAi larvae. Moreover, two InRs and Torso were highly expressed in the final larval instars. Furthermore, RNAi of either Lddrk or Ldchico, or both of them equally affected larval-pupal and pupal-adult molts, and similarly repressed the expression of representative MAPK (Ldras and Ldraf), ecdysteroidogenesis (Ldphm and Ldsad), and 20E signaling (LdEcR, LdUSP, LdHR3 and LdE75) genes. 20E feeding by Lddrk RNAi larvae completely restored the reduced mRNA levels of LdEcR, LdHR3 and LdE75, but did not rescued the decreased Lddrk and LdUSP levels and the lowered pupation and emergence rates. Therefore, our findings suggest that the Drk-MAPK branch is involved in metamorphosis regulation in L. decemlineata.

      • Value of Ultrasound Elastography in Assessment of Enlarged Cervical Lymph Nodes

        Teng, Deng-Ke,Wang, Hui,Lin, Yuan-Qiang,Sui, Guo-Qing,Guo, Feng,Sun, Li-Na Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        Background: To investigate the value of ultrasound elastography (UE) in the differentiation between benign and malignant enlarged cervical lymph nodes (LNs). Methods: B-mode ultrasound, power Doppler imaging and UE were examined to determine LN characteristics. Two kinds of methods, 4 scores of elastographic classification and a strain ratio (SR) were used to evaluate the ultrasound elastograms. Results: The cutoff point of SR had high utility in differential diagnosis of benign and malignant of cervical lymph nodes, with good sensitivity, specificity and accuracy. Conclusion: UE is an important aid in differential diagnosis of benign and malignant cervical LNs.

      • Analysis of Factors Influencing Communication Popularity Based on Short Video Information Sources: Audience Trust as a Mediated Research Review

        Xin Guo(Guo Xin ),Fang Deng(Deng Fang ) 동북아경상학회 2022 동북아경상연구 Vol.3 No.1

        Purpose – In the online environment, the group definition, marginal scope, and transmission methods of short video creators and audiences have all changed, but the centrality of the audiences’ essence will not change. Their thinking characteristics and behaviors ultimately determine the influence of digital products spread in the network. This paper attempts to explore the relationship between audience trust and communication mechanism from the source of information: the trust or suspicion generated by the creator’s identity type information, and explore its influence on the popularity of communication. Design/Methodology/Approach – We systematically reviews the connotation and extension of audience trust in online media, definition and characteristics of network identity, the disclosure of creator identity types, character setting, authentication and supervision of identity, and communication popularity. Findings – The interaction between short video media and audience includes: information dissemination, value judgment and emotional transmission. Audience trust plays a bridge and check position in the dissemination of short video media, which determines the survival and development of short video media. These contents can provide short video creators with basic information that can effectively affect user behavior, provide them with a basis for decisionmaking in the creation process, increase audience trust, and improve the popularity and effectiveness of media communication. Research Implications – It provides a new research perspective for influencing user identification, social recommendation and other fields.

      • SCIESCOPUSKCI등재

        Association of a Single Codon Deletion in Bone Morphogenetic Protein 15 Gene with Prolificacy in Small Tail Han Sheep

        Guo, W.,Chu, M.X.,Deng, X.M.,Feng, J.D.,Li, Ning,Wu, Changxin Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.11

        Small Tail Han Sheep has significant characteristics of high prolificacy and non-seasonal ovulatory activity and is an excellent local sheep breed in P. R. China. Recently a novel member of the transforming growth factor $\beta$ (TGF$\beta$) superfamily termed bone morphogenetic protein 15 (BMP15) was shown to be specifically expressed in oocytes and to be essential for female fertility. Therefore, BMP15 is a candidate gene for reproductive performance of Small Tail Han Sheep. The whole genomic nucleotide sequence of BMP15 gene in Small Tail Han Sheep was searched for polymorphisms by PCR-SSCP and direct sequencing, and only one polymorphism was found. The polymorphism was a result of a 3 base pair deletion, which eliminated a single Leu codon (CTT). The allelic frequencies for A (without deletion) and B (with a codon deletion) are 0.73 and 0.27 respectively. The effects of BMP15 genotype on litter size were evaluated using the least squares model. This indicated that there was a significant association between litter size of Small Tail Han Sheep and a deletion in BMP15 gene (p=0.02<0.05). Small Tail Han Sheep ewes with AA and AB genotype produce on average 0.5 and 0.3 more lambs per litter than those ewes with BB genotype.

      • KCI등재

        A Characteristic Analysis and Countermeasure Study of the Hedging of Listed Companies in China Stock Markets

        Guo-Hua WU,Xiao-Ling JIANG,Su-Ya DENG 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.10

        Due to COVID-19, the risk of price volatility in commodity and equity markets increases. The research and application of hedging is the most effective way to reduce the market risk. Hedging is a risk management strategy employed to offset losses in investments by taking an opposite position in a related asset. We use K-means and hierarchical clustering methods to cluster companies and futures products respectively, and analyze the relationship between the number of hedging firms, regional distribution, nature of firms, capital distribution, company size, profitability, number of local Futures Commission Merchants (FCMs), regional location, and listing time. The study shows that listed companies with large scale and good profitability invest more money in hedging, while state-owned enterprises’ participation in hedging is more likely to be affected by the company size and the number of local futures commission merchants, and private enterprises are more likely to be affected by the company profitability and the regional location. Listed companies are more willing to choose long-listed and mature futures products for hedging. We also provide policy advice based on our conclusion. So far, there is no study on the characteristics of hedging. This paper fills the gap. The results provide a basis and guidance for people’s investment and risk management. Using clustering analysis in hedging study is another innovation of this paper.

      • KCI등재

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