Endodontic treatment of mandibular molar with root dilaceration using Reciproc single-file system

Daniely Amorin Meireles,Mariana Mena Barreto Bastos,André Augusto Franco Marques,Lucas da Fonseca Roberti Garcia,Emílio Carlos Sponchiado Júnior 大韓齒科保存學會 2013 Restorative Dentistry & Endodontics Vol.38 No.3

Biomechanical preparation of root canals with accentuated curvature is challenging. New rotatory systems, such as Reciproc, require a shorter period of time to prepare curved canals, and became a viable alternative for endodontic treatment of teeth with root dilaceration. Thus, this study aimed to report a clinical case of endodontic therapy of root with accentuated dilaceration using Reciproc single-file system. Mandibular right second molar was diagnosed as asymptomatic irreversible pulpitis. Pulp chamber access was performed, and glide path was created with #10 K-file (Dentsply Maillefer)and PathFile #13, #16 and #19 (Dentsply Maillefer) up to the temporary working length. The working length measured corresponded to 20 mm in the mesio-buccal and mesio-lingual canals, and 22 mm in the distal canal. The R25 file (VDW GmbH) was used in all the canals for instrumentation and final preparation, followed by filling with Reciproc gutta-percha cones (VDW GmbH) and AH Plus sealer (Dentsply Maillefer),using thermal compaction technique. The case has been receiving follow-up for 6mon and no painful symptomatology or periapical lesions have been found. Despite the difficulties, the treatment could be performed in a shorter period of time than the conventional methods.

Endodontic treatment of mandibular molar with root dilaceration using Reciproc single-file system

Meireles, Daniely Amorin,Bastos, Mariana Mena Barreto,Marques, Andre Augusto Franco,Garcia, Lucas Da Fonseca Roberti,Sponchiado, Emilio Carlos Junior The Korean Academy of Conservative Dentistry 2013 Restorative Dentistry & Endodontics Vol.38 No.3

Biomechanical preparation of root canals with accentuated curvature is challenging. New rotatory systems, such as Reciproc, require a shorter period of time to prepare curved canals, and became a viable alternative for endodontic treatment of teeth with root dilaceration. Thus, this study aimed to report a clinical case of endodontic therapy of root with accentuated dilaceration using Reciproc single-file system. Mandibular right second molar was diagnosed as asymptomatic irreversible pulpitis. Pulp chamber access was performed, and glide path was created with #10 K-file (Dentsply Maillefer) and PathFile #13, #16 and #19 (Dentsply Maillefer) up to the temporary working length. The working length measured corresponded to 20 mm in the mesio-buccal and mesio-lingual canals, and 22 mm in the distal canal. The R25 file (VDW GmbH) was used in all the canals for instrumentation and final preparation, followed by filling with Reciproc gutta-percha cones (VDW GmbH) and AH Plus sealer (Dentsply Maillefer), using thermal compaction technique. The case has been receiving follow-up for 6 mon and no painful symptomatology or periapical lesions have been found. Despite the difficulties, the treatment could be performed in a shorter period of time than the conventional methods.

Effect of ultrasonic tip designs on intraradicular post removal

Anny Carine Barros Aguiar,Daniely Amorim de Meireles,André Augusto Franco Marques,Emílio Carlos Sponchiado Júnior,Angela Delfina Bitencourt Garrido,Lucas da Fonseca Roberti Garcia 대한치과보존학회 2014 Restorative Dentistry & Endodontics Vol.39 No.4

Objectives: To evaluate the effect of different ultrasonic tip designs on intraradicular post removal. Materials and Methods: The crowns of forty human canine teeth were removed, and after biomechanical preparation and filling, the roots were embedded in acrylic resin blocks. The post spaces were made, and root canal molding was performed with self-cured acrylic resin. After casting (Cu-Al), the posts were cemented with zinc phosphate cement. The specimens were randomly separated into 4 groups (n = 10), as follows: G1 - no ultrasonic vibration (control); G2 - ultrasonic vibration using an elongated cylindrical-shaped and active rounded tip; G3 - ultrasonic vibration with a flattened convex and linear active tip; G4 - ultrasonic vibration with active semicircular tapered tip. Ultrasonic vibration was applied for 15 seconds on each post surface and tensile test was performed in a Universal Testing Machine (Instron 4444 - 1 mm/min). Results: G4 presented the highest mean values, however, with no statistically significant difference in comparison to G3 (p > 0.05). G2 presented the lowest mean values with statistically significant difference to G3 and G4 (p < 0.05). Conclusions: Ultrasonic vibration with elongated cylindrical-shaped and active rounded tip was most effective in reducing force required for intraradicular post removal.

Efficacy of instillation of MB49 cells and thermoreversible polymeric gel in urothelial bladder carcinoma immunization

Jhonne Pedro Pedott Santana,Priscyla Daniely Marcato,Tais Nader Chrysostomo Massaro,Naiane Lima Godoy,Fernanda de Freitas Anibal,Borra Ricardo Carneiro 한국실험동물학회 2022 Laboratory Animal Research Vol.38 No.2

Background: Activating the immune system for therapeutic benefit has long been a goal in immunology, especially in cancer treatment, but the low immunogenicity of antitumor vaccines remains a limiting factor in the fight against malignant neoplasms. The increase in the immunogenicity of weak antigens using biodegradable polymers, such as chitosan, has been observed in the field of cancer immunotherapy. However, the effects of the vaccine using a combination of tumor cells and a thermoreversible delivery system based on chitosan in bladder cancer models, mainly using the intravesical route to stimulate the antitumor immune response, are unknown. We propose to evaluate the efficacy of a polymeric gel matrix (TPG) formed by poloxamer 407 and chitosan, associated with MB49 cells, as an intravesical antitumor vaccine using a C57BL/6 murine model of bladder urothelial carcinoma. The effectiveness of immunization was analyzed with the formation of three experimental groups: Control, TPG and TPG + MB49. In the vaccination phase, the TPG + MB49 group underwent a traumatic injury to the bladder wall with immediate intravesical instillation of the vaccine compound containing MB49 cells embedded in TPG. The TPG group was subjected to the same procedures using the compound containing the gel diluted in medium, and the control group using only the medium. After 21 days, the animals were challenged with tumor induction. Results: In vitro tests showed loss of viability and inability to proliferate after exposure to TPG. In vivo tests showed that animals previously immunized with TPG + MB49 had higher cumulative survival, as well as significantly lower bladder weight and size in contrast to the other two groups that did not show a statistically different tumor evolution. In addition, the splenocytes of these animals also showed a higher rate of antitumor cytotoxicity in relation to the TPG and control groups. Conclusions: We can conclude that MB49 cells embedded in a polymeric thermoreversible gel matrix with chitosan used in the form of an intravesical vaccine are able to stimulate the immune response and affect the development of the bladder tumor in an orthotopic and syngeneic C57BL/6 murine model.

Effect of ultrasonic tip designs on intraradicular post removal

Aguiar, Anny Carine Barros,de Meireles, Daniely Amorim,Marques, Andre Augusto Franco,Sponchiado, Emilio Carlos Junior,Garrido, Angela Delfina Bitencourt,Garcia, Lucas Da Fonseca Roberti The Korean Academy of Conservative Dentistry 2014 Restorative Dentistry & Endodontics Vol.39 No.4

Objectives: To evaluate the effect of different ultrasonic tip designs on intraradicular post removal. Materials and Methods: The crowns of forty human canine teeth were removed, and after biomechanical preparation and filling, the roots were embedded in acrylic resin blocks. The post spaces were made, and root canal molding was performed with self-cured acrylic resin. After casting (Cu-Al), the posts were cemented with zinc phosphate cement. The specimens were randomly separated into 4 groups (n = 10), as follows: G1 - no ultrasonic vibration (control); G2 - ultrasonic vibration using an elongated cylindrical-shaped and active rounded tip; G3 - ultrasonic vibration with a flattened convex and linear active tip; G4 - ultrasonic vibration with active semicircular tapered tip. Ultrasonic vibration was applied for 15 seconds on each post surface and tensile test was performed in a Universal Testing Machine (Instron 4444 - 1 mm/min). Results: G4 presented the highest mean values, however, with no statistically significant difference in comparison to G3 (p > 0.05). G2 presented the lowest mean values with statistically significant difference to G3 and G4 (p < 0.05). Conclusions: Ultrasonic vibration with elongated cylindrical-shaped and active rounded tip was most effective in reducing force required for intraradicular post removal.

90-Day Oral Toxicity Assessment of Tropaeolum majus L. in Rodents and Lagomorphs

Valdinei de Oliveira Araujo,Carlos Eduardo Linhares Andreotti,Michelle de Paula Reis,Daniely Alves de Lima,Karoline Bach Pauli,Bruna Caroline Nunes,Caroline Gomes,Ricardo de Melo Germano,Euclides Lara 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.8

Tropaeolum majus L., popularly known as nasturtium, is a species widely used in the form of infusions and salads. In the last years, the antihypertensive, diuretic, and calcium and potassium sparing activities of T. majus preparations were shown. Moreover, no preclinical 90-day oral toxicity studies were conducted. Thus, this study evaluated the toxicity of the hydroethanolic extract obtained from T. majus (HETM) leaves in female and male mice, rats, and rabbits. Swiss mice and Wistar rats were treated with HETM (75, 375, and 750 mg/kg). The doses of rabbits (30, 150, and 300 mg/kg) were calculated by allometric extrapolation. The control groups received vehicle. The animals were orally treated, daily, for 90 days. At the end, the animals were anesthetized, and body weight gain, relative weight of liver, kidney, and spleen, and histopathological changes were evaluated. Serum hematological and biochemical parameters were also analyzed. No alterations were found in body and organ weights or in histopathological and biochemical evaluation. Hematological analyses revealed small changes in lymphocytes and neutrophil counts in rats after administration of 750 mg/kg of HETM. These results showed that 90-day use of T. majus is safe in rodents and lagomorphs.

European Union Emission Trading System How far will the european union dare to go?

Daniè,le Barberis 유럽헌법학회 2009 유럽헌법연구 Vol.5 No.-

유럽연합 입법부가 2003년 10월111)에 교토 협안112)(2002년 4월) 안에 있는 방사물들 감소에 대처하기 위하여 (2005년에 시작된 하나의 단계) CO2 방사물 상업에 종사하는 자를 위하여 계획안을 제의하였다(EU 방사물 상업종사 계획안 또는 ETS). 3년 후에 첫 번째 계획안 단계가 끝남으로써 무엇보다도 두 번째와 세 번째 단계에 관해서 말로 표명되어 있는 관여물들이 두 번째 단계에 천천히 탄력이 붙었다. 이 문제점들은 가지각색의 주 구성원의 주권과 유럽 법령의 집중된 힘 사이에서 균형을 유지하기 위하여 유럽연합법들이 노력하고 있는 것에 깊이 생각되어질 것이다. 주요 논점들은 다음과 같다. 유럽은 환경 보호를 위하여 다량의 산업의 급증하는 요구를 반대할 예정인가? ETS에 의하여 축적된 막대한 유로의 이익을 얻는 것은 유럽연합과 구성원 중 누구인가? 무엇보다도 : 유럽연합 행정부와 입법부가 어떻게 CO2 방사물 감소지역에 가려고 노력할 것인가? In October 2003, in order to meet emission reduction objectives as laid down within the Kyoto Protocol (April 2002), the European Union (EU) Legislature has set up a scheme (whose phase one started in 2005) for trading CO2 emission allowances (‘EU Emission Trading Scheme’ or ETS). Three years later, as the first phase of the scheme ends and the second phase slowly gains momentum, concerns are being voiced regarding this second phase and above all the third phase. Issues are to be considered in the light of the EU Law’s struggle to set a balance between its various States Members national sovereignty and the centralized power of European Institutions. The mains questions are as follows. Is Europe’s heavy industry going to resist the ever-growing demand for environmental protection? Who from the European Union or the Member States is going to benefit from the billions of Euros amassed by the ETS? Above all: how far will the European Union executive branch and legislature dare to go in the field of CO2 emission reduction?

Tajdīd (Renewal) in Sufism: An Examination of Khālid al-Baghdādī’s Thoughts and Practices from the Perspective of Social Capital Theory

( İdiris Danişmaz ) 부산외국어대학교 지중해지역원 2019 The Mediterranean Review Vol.12 No.1

Renewal (tajdīd) has been one of the most controversial issues in the Islamic world. Throughout Islamic history, and especially since the Ottoman Empire started to lose ground to the West, there has been much debate about matters that need changing and how change should happen. One group that was both the subject and the agent of the change was the Sufis. One such influential Sufi mujaddid (innovator) was Khālid al-Baghdādī (d.1827). His innovative approaches have allowed Sufism to transform into activism, serving as a model for Sufis as well as for non-Sufi movements across all sectors of life. This study, which explores some conceptual similarities between Khālid al-Baghdādī’s innovative practices and social capital, analyzes his thoughts, and offers a conceptual framework in order to explain the complexity of the activities of the organizations he influenced, and to describe the process of producing social activism out of Sufism and the Sufi orders (ṭarīqa). It is hoped this study, by being the first attempt to look at Sufism from the perspective of social capital theory will serve as a starting point for further research.

Constitutive model coupled with damage for carbon manganese steel in low cycle fatigue

Zhiyong Huang,Qingyuan Wang,Danièle Wagner,Claude Bathias 국제구조공학회 2014 Steel and Composite Structures, An International J Vol.17 No.2

Carbon-manganese steel A42 (French standards) is used in steam generator pipes of nuclear center and subject to low cycle fatigue (LCF) loads. In order to obtain the material LCF behavior, the tests are implemented in a hydraulic fatigue machine. The LCF plastic deformation and cyclic stress in macroscope have been influenced by the accumulated low cycle fatigue damage. The constitutive kinematic and isotropic hardening modeling is modified with coupling fatigue damage to describe the fatigue behavior. The improved model seems to be good agreement with the test results.

Resistance to Pit Formation and Pit Growth for Different Tempers of AA2024 Aluminium Alloy in Presence of Benzotriazole

Bore Jegdić,Biljana Bobić,Maja Stevanović,Marija Mihailović,Dunja Daničić,Jovanka Kovačina,Bojana Radojković 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.11

The paper analyses the corrosion behaviour of both naturally and artificially aged AA2024 aluminium alloy in NaCl solutionin the presence of the corrosion inhibitor benzotriazole (BTA). The differences between these two aging tempers in termsof resistance to general corrosion are explained as well as the differences in terms of pit formation and pit growth. Basedon the values of the polarisation resistance and the corrosion current density, the general corrosion resistance of the alloyis determined in the absence and in the presence of BTA. The resistance to pit formation and pit growth is determined onthe basis of the polarisation measurements results. Scanning electron microscopy confirmed the expected differences in theappearance and size of the pits formed in naturally aged and artificially aged alloy. In the presence of the corrosion inhibitorBTA, for both aging tempers of the alloy, the corrosion resistance is significantly higher compared to the resistance in thesolution without the inhibitor. The value of the polarisation resistance for both aging tempers increases over time. However,at the same time, the value of the constant phase element increases as well. An explanation for this phenomenon is provided. The calculated average value of the thickness of the adsorbed inhibitor layer on the surface of the aluminium alloy is inaccordance with the inhibitor protective ability for both aging tempers.