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      • KCI등재

        팬데믹 시대, ‘공간’을 주제로 한 글쓰기치료 수업 모형 연구

        홍단비 ( Hong¸ Dan-bi ) 한국문학치료학회 2022 문학치료연구 Vol.62 No.-

        본고는 팬데믹 시대, 사회적 거리두기와 관계의 단절 등으로 고립감과 우울감 등을 경험하는 20대들에게 심리적인 도움이 필요하다는 점, 팬데믹 시대, 집안이나 실내 공간에 머무는 시간이 크게 증가한 대학생들에게 ‘공간’에 대한 사유가 필요하다는 두 가지 문제의식을 바탕으로, 팬데믹 시대 ‘공간’을 주제로 한 글쓰기치료 수업 모형을 제시하였다. 4차시로 구성된 본 수업 모델은 글쓰기치료의 4단계 과정에 따라 고안된 모델로, 체베나 쓰기를 통한 무의식 속 공간 탐색(1차시), 나의 기억 속 토포필리아 탐색(2차시), 토포필리아의 공유를 통한 공간의식의 확장(3차시), 현재 나에게 가장 의미있는 공간 찾기와 소감 쓰기(4차시)의 과정으로 진행되었다. 그 결과 다음과 같은 논의를 이끌어 낼 수 있었다. 첫째, 공간을 주제로 한 글쓰기는 팬데믹 시대, 자신의 리비도가 가장 많이 투영되어 있는 공간을 발견하고, 그 공간에서의 행위와 의미들을 탐색할 수 있게 한다. 둘째, 토포필리아에 대한 글쓰기는 과거의 소중한 공간에 대한 기억과 감정들을 되살아나게 함으로써 공간의 중요성과 공간의 가치를 깨닫게 한다. 셋째, 수업시간에 발표를 통해 공유하는 공간에 대한 기억은 공간에 대한 이해와 깊이를 확장하게 하며, 확장된 공간의식을 바탕으로 현재 자신에게 가장 의미 있는 공간을 탐색하는 활동을 통해 학생들은 자신의 성격과 취향, 자신의 가치관과 삶의 태도 등을 성찰할 수 있다. 넷째, 공간에 대한 글쓰기는 안전하고 조용한 글쓰기 공간 안에서 내면의 억압된 것들을 자유롭게 표출하고, 자신의 생각과 감정들을 정리하게 함으로써 글쓰기의 가치와 치유적 효과를 경험하게 한다. 이처럼 팬데믹 시대, ‘공간을 주제로 한 글쓰기’는 학생들에게 구속과 제약, 답답함이나 무료함 너머, 공간의 다양성과 가능성, 그리고 공간의 소중함과 중요성 등을 탐색할 수 있는 계기를 마련해 줄 수 있으며, 자신이 점유하고 있는 생활공간에 애착을 부여하게 함으로써, 학생들의 주체성 형성에도 긍정적인 영향을 미칠 수 있을 것이다. This paper presents a writing therapy class model of “space” in the pandemic era based on the awareness of two problems. First, psychological help is needed for those in their 20s who experience feelings of isolation and depression due to social distancing and disconnection. Second, college students have significantly increased their time at home or indoors during the pandemic. These problems have in common the fact that selecting “space” is necessary. This class model, which consists of four lessons, is designed according to the four-step process of writing therapy. Chronologically, the process goes as follows: exploration of space in the unconscious through writing Chevena; exploration of topophilia in memory; expansion of spatial consciousness by sharing topophilia; and finding the most meaningful space at present and writing one’s impressions. As a result, we find the following. First, writing on the subject of space allows one to discover the space where one’s libido is most projected in the pandemic era. It also enables one to explore the actions and meanings in that space. Second, writing about topophilia conveys the importance and value of space by reviving memories and emotions about precious spaces of the past. Third, the memory of the spaces shared through conversation in class expands its understanding and depth. In addition, students can reflect on their personalities, tastes, values, a n d attitudes toward life through activities that explore the space that is most meaningful to them now. Fourth, writing about space allows students to freely express their inner repressed feelings in a safe and quiet writing space, and by having students organize their thoughts and feelings, they experience the value and healing effect of writing. Thus, “space-themed writing” in the pandemic era will provide students with an opportunity to explore the diversity, possibilities, specialness, and importance of space, rather than the constraints and restrictions of and stuffiness and boredom brought about by the pandemic. Moreover, by making them attach themselves to the living space that they occupy, it will have a positive effect on the formation of their identity.

      • KCI등재

        밀로 라우의 뉴리얼리즘 -재연을 통한 허구와 실재의 작용-

        이단비 ( Yi¸ Dan-bi ) 한국드라마학회 2021 드라마연구 Vol.- No.65

        밀로 라우는 2018년 겐트 선언문을 통해서 연극은 더 이상 세상을 보여주는 게 아니라 세상을 바꿔야 한다고 주장한다. 연극은 세상의 진실을 보여줄 수 있어야 하고, 이를 통해 변화의 가능성들이 제기되어야 한다는 것이다. 그는 논쟁의 여지가 많은 역사 속 사건을 선택하고 그것을 재연이라는 방식을 통해 현재로 소환한다. 이때 재연은 과거의 사건을 현실에서 연극이라는 허구의 세계로 옮겨오는 역할을 수행한다. 리얼리즘이 재현을 통해 연극의 허구성을 감추고 완결된 환상을 지향한다면, 라우는 재연을 통해 연극의 허구성을 인정하고 환상이 아닌 실재를 연출하는 뉴리얼리즘을 주장한다. 허구와 실재라는 서로 상반되는 개념이 충돌하고 공존하면서 연극 안에서 과거의 사건은 현재로 소환된다. 관객은 역사적 사건에 감정적으로 이입되는 동시에, 지금 관객의 눈앞에서 다시 반복되는 사건의 현재화를 통해 퍼포먼스적인 측면에서의 현장성을 경험한다. 무엇보다 재연은 과거 사건에 대한 하나의 입장 혹은 태도를 전제하기 때문에, 연출가의 예술적 해석을 반영한다. 본 논문에서는 라우의 독특한 연극 미학을 고찰하고, 그가 2016년에 연출한 <다섯 개의 소품들>을 중심으로 재연이라는 방식이 어떻게 작동하고 어떠한 의미를 산출하는지에 집중한다. 무엇보다 그가 일관되게 사용하는 재연 기법이 초기 작품에서 현재에 이르기까지 어떻게 변주되는지 그 양상을 추적하고 이에 따른 효과를 분석하고자 한다. 이를 통해 아직 국내에서 활발하게 다뤄지지 않은 라우의 연극 미학에 대한 관심을 촉발하고 이후 연구를 위한 초석을 마련하고자 한다. In 2018, Milo Rau proclaims in his Ghent Manifesto that theater is not just about portraying the world anymore. It’s about changing it. Theatre should be able to reveal the truths of the world and the possibilities of change must be raised through this. He chooses controversial events from the past and summons them to our present by using the form of ‘reenactment’. This reenactment plays a pivotal role of transferring the reality of the past events into the fictional world of theater. In other words, if ‘Realism’ pursues the complete illusion which hides the fictionality of theater through the representation of reality, then what Rau suggests is that he accepts the fictional aspects of theater, but instead of directing illusion he directs the reality. Which is what he calls the ‘New Realism’. In Rau's plays, the past events become our present as the two of the opposing ideas, so called fiction and reality clashes and co-exists. As the audiences make the emotional connection to the past events, they also witness and experience the liveness as in the form of performance through the past events being repeated in front of their present eyes. Most of all, the reenactment premises one of many stances or opinions about the past events, so it reflects the director’s artistic interpretation. In this dissertation, I will be contemplating Rau’s distinctive theatrical aesthetics, and focus on the mechanism of reenactment, and what meanings it produces by studying the play Five Easy Pieces which he directed in 2016. Above all, I will be tracking the variations of his consistent use of this reenactment method from his early plays to the most recent ones and analyze the effects that follows. Through this, I wish to trigger the interests toward Rau’s aesthetics of theatre, which hasn’t been actively mentioned in Korea. And thus create a foundation for a further study of Milo Rau and his theatre.

      • The sex and age dependant differences in ECG values in C57BL6/N mice

        Danbi Ka,Jieun Kim,Eun-Kyoung Kim,Hae-Rim Kim,Sang-Mi Cho,Seulgi Park,Faiz Ur Rahman,Mini Lee,Ki-Hoon Lee,Hoyoung Ghang,Won-Kee Yoon,Young-Suk Won,Hyoung-Chin Kim,Kyoung-Chul Choi,Ki-Hoan Nam 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

        Eelectrocardiogram (ECG) is a surface recording of the electric current passing through the heart, revealing the electrical activity associated with each heartbeat, and allowing visualization of the electrical state of the heart. In a state of consciousness, normal rat heart rates range from 500 to 700 beats per minute (bpm). ECG reflects the cycle of the heart and consists of P, Q, R, S and T waves. The non-invasive ECG system has the advantage of acquiring information not only on heart rate, but also on heart rate variability, RR, QT and PR intervals, as well as acquiring cardiac abnormalities in conscious animals. In this study, we conducted experiments ECG analysis with 12 weeks and 56 weeks aged male and female C57BL/6N mice. We compared the ECG values between male and female mice and between 12 weeks and 56 weeks aged mice, comparing age and gender differences. There were sex differences in HR and RR in 12 weeks aged mice and in HR and QRS in 56 weeks aged mice. We also found age dependant differences in QRS, ST, HR and RR in male mice and in PR, ST and QTc in female mice. These result indicate that there is age and sex differences in ECG values.

      • KCI등재SCOPUSSCIE

        Structure-Based Insight on the Mechanism of N-Glycosylation Inhibition by Tunicamycin

        Danbi Yoon,Ju Heun Moon,Anna Cho,Hyejoon Boo,Jeong Seok Cha,Yoonji Lee,Jiho Yoo Korean Society for Molecular and Cellular Biology 2023 Molecules and cells Vol.46 No.6

        N-glycosylation, a common post-translational modification, is widely acknowledged to have a significant effect on protein stability and folding. N-glycosylation is a complex process that occurs in the endoplasmic reticulum (ER) and requires the participation of multiple enzymes. GlcNAc-1-P-transferase (GPT) is essential for initiating N-glycosylation in the ER. Tunicamycin is a natural product that inhibits N-glycosylation and produces ER stress, and thus it is utilized in research. The molecular mechanism by which GPT triggers N-glycosylation is discussed in this review based on the GPT structure. Based on the structure of the GPT-tunicamycin complex, we also discuss how tunicamycin reduces GPT activity, which prevents N-glycosylation. This review will be highly useful for understanding the role of GPT in the N-glycosylation of proteins, as well as presents a potential for considering tunicamycin as an antibiotic treatment.

      • KCI등재

        Lipocalin-2 Secreted by the Liver Regulates Neuronal Cell Function Through AKT-Dependent Signaling in Hepatic Encephalopathy Mouse Model

        Danbi Jo,Yoon Seok Jung,Juhyun Song 한국임상영양학회 2023 Clinical Nutrition Research Vol.12 No.2

        Hepatic encephalopathy (HE) associated with liver failure is accompanied by hyperammonemia, severe inflammation, depression, anxiety, and memory deficits as well as liver injury. Recent studies have focused on the liver-brain-inflammation axis to identify a therapeutic solution for patients with HE. Lipocalin-2 is an inflammation-related glycoprotein that is secreted by various organs and is involved in cellular mechanisms including iron homeostasis, glucose metabolism, cell death, neurite outgrowth, and neurogenesis. In this study, we investigated that the roles of lipocalin-2 both in the brain cortex of mice with HE and in Neuro-2a (N2A) cells. We detected elevated levels of lipocalin-2 both in the plasma and liver in a bile duct ligation mouse model of HE. We confirmed changes in cytokine expression, such as interleukin-1β, cyclooxygenase 2 expression, and iron metabolism related to gene expression through AKT-mediated signaling both in the brain cortex of mice with HE and N2A cells. Our data showed negative effects of hepatic lipocalin-2 on cell survival, iron homeostasis, and neurite outgrowth in N2A cells. Thus, we suggest that regulation of lipocalin-2 in the brain in HE may be a critical therapeutic approach to alleviate neuropathological problems focused on the liver-brain axis.

      • KCI등재

        A Systematic Review and Meta-Analysis of Applicability of Web-Based Interventions for Individuals with Depression and Quality of Life Impairment

        Danbi Yang,Ji-Won Hur,Yoo Bin Kwak,Sung-Won Choi 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.8

        Objective_The purpose of this meta-analysis was to determine the applicability of web-based treatment programs for individuals with depression and quality of life impairments. Methods_We conducted database and manual searches using imprecise search-term strategy and inclusion criteria. Research published from 2005 to December 2015 was included in this study. Upon review, a total of 12 published papers on web-based intervention for individuals with depression were assessed eligible for this meta-analysis. Effect sizes were estimated for depression and quality of life. Results_The mean effect size of web-based treatment on depressive symptoms was 0.72. However, unlike the result showing medium to large effect size, the analysis on the quality of life did not yield adequate effects of web-based interventions. Conclusion_Our results suggest robust benefits of employing web-based treatments for depressive symptoms. However, the adequacy of these relatively new intervention tools for individuals who suffer severe impairments of quality of life was found insufficient. The current study demonstrates the need to further develop web-based intervention techniques to improve overall functioning, as well as the clinical symptoms of patients with mental disorders.

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