허혈성 심질환에서 염증지표에 관한 연구

번정득,권영주,박상호,한대희,이상철,강진환,김명구,심규혁,최병조,온영근,현민수,김성구 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background : Atherosclerosis is the chief underlying cause of ischemic heart disease and there is increasing evidence that inflammation is an important determinant of the development of atherosclerosis. We assessed the levels of inflammatory markers in patients with ischemic heart disease and normal group who has normal coronary angiograms. Materials and Methods : Coronary angiography was performed in 142 patients. 107 patients of ischemic heart disease(stable angina pectoris 58, unstable angina pectoris 30, Acute myocardial infarction 19) and 38 normal control subjects. We assessed the level of inflammatory markers, such as CRP, ESR, fibrinogen and leukocyte. Results : CRP, ESR and fibrinogen values of the patients with stable angina pectoris and unstable angina pectoris were higher than that of normal control group, but there were no statistical significance. Leukocyte value of the patients with unstable angina pectoris(9003.3±701.5/mm^(3)) was significantly higher than that of the patients with stable angina pectoris(6685.5±245.8/mm^(3)) and normal control subjects(6394.3±235.1/mm^(3)). CRP, ESR and fibrinogen values of the patients with acute myocardial infarction were also higher than that of normal control subjects. CRP was 3.88±2.05 mg/dL in acute mocardial infarction group, and 0.29±0.15 mg/dL in normal control subject group(p<0.05). Fibrinogen was 541.6±45.1 mg/dL in acute myocardial infarction group, 321.4±25.6 mg/dL in normal control subject group(p<0.05). Leukocyte was 10942.1±737.6/mm^(3) in acute myocardial infarction group, 6394.3±235.1/mm^(3) in normal control subject group(p<0.05). Conclusions : This study demonstrate that CRP, fibrinogen and leukocyte values of acute myocardial infarction group were significantly higher than that of control group and stable, unstable argina pectoris group. Leucokyte values were significantly elevated in unstable angina group, but CRP values were not in unstable angina group.

정보화시대의 공동체 : 정보화의 진전과 기업·소비자 관계 변화를 중심으로

이대식,김성국,김영삼,신종국,임정덕,조영복,조정문 釜山大學校 商科大學 2000 釜山商大論集 Vol.71 No.-

In this study, we questioned about the possibility of the formation of the new community like relationship at the market on the contrary to the traditional market relationship. We conjectured that kind of new community like relationship may possibly arise because of wide spread of new information technology at market behavior of both consumer and producer side. Traditional buyer-seller relationship was characterized as an anonymous one-shot relationship, however, recent changes were mainly emphasized the rich mutual interactions from both sides. Producers needs more consumer side informations as well as consumers begin to participate on production side at more organized level. Some theoretical studies predict that more rich social relationship will appear at the market since the adoption and wide spread of new information technology. We assume that main functions and ingredients of the community are first, the coordination mechanism which reduces conflicts among community members and second, functional efficiency which meets the common needs of community and third, communicational rationality which enhances the integrity of community members. We surveyed about 100 small and medium sized firms located at Pusan and Kyung-Nam area in order to find out whether firms have community like relationship with their consumers. We fine that most of firms realize the impotance of consumer networks, however most of firms consider this kind of network as a marketing strategy and a source of product design instead of more community oriented characteristics like mutual trust building and social interactions.

주택사업의 유형별 입주자의 비용 : 편익분석 Evaluation in terms of Housing Occupants

윤대식,김규덕 영남대학교 지역발전연구소 1994 새마을지역개발연구 Vol.16 No.-

The purpose of this paper is to evaluate the effectiveness of alternative housing supply programs in terms of housing occupants. For this purpose, cost-benefit analysis is applied in terms of housing occupants, rather than housing supplier. For this study, 11 types of housing supply programs are considered, and 11 housing projects which were done in Taegu are selected for the analysis. The results of cost-benefit analysis show that rental housing supply program provides the highest net benefit to housing occupants. Furthermore, it is found that the housing supply program with greater housing space tends to provide greater net benefit.

러시아 농업과학기술 연구기관과 운영체체의 변화

이상덕,김종환,정남진,오대근,오성종 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.2

This work is dedicated to main directions of Agricultural science policy of Russia during the transition to the market economy. In this study, Russian R&D system, R&D expenditure and structure of research institutes were introduced. Especially, Studies on organizations such as RFBR : Russian Foundation for Basic Research, RFTD : Russian Fund for Technological Development, Russian Foundation for Promotion of Small Enterprises in S&T, FPP : Fund for presidential Programs, SRC : State Research Center, ISTC : International Science & Technology Center were carried out. Analysis of the problems of Agricultural Science sector of Russia shows the situation is very complicated. Despite all efforts of Government, the national institutes is still in crisis. It is clear today that without energetic and intelligent reforms, it would be impossible to implement resonable reorganization of Agricultural sector and have to strong and deserved science and technical sector in Russia.

4,5-bis(hexanoyloxy)의 dodecame 合成 및 그 潤滑性

金鍾大,崔在煥,林得根 嶺南大學校附設 基礎科學硏究所 1985 基礎科學硏究 Vol.5 No.-

4,5-Bis(hexanoyloxy) dodecane was syntheisized from 4,5-dodecanediol which was obtained through continuous reaction steps starting from n-octyl alcohol. All the intermediates and final products were purified by way of distillation or crystallization, and confirmed by IR spectrophotometer and refractometer. Physical properties of the diester synthesized were also determined for the flowing point and solidifying point. It was observed that the flowing point of the diester was under-78℃, and it appeared that the diester synthesized is much more superior to the common mineral lubricant on the base of the solidifying temperature.

釜山地域産業의 成長要因分析 : 1985-1990

이대식,임정덕,최기환 부산대학교 1995 地域經濟硏究 Vol.- No.4

스포츠 관련인자에서 본 여자중학생의 골밀도에 관한 연구

김덕중,이신언,김대경 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1

In order to obtain the basic data for the relationship between factors related to sports and bone density of middle school girls, bone densities of a heel were measured, and physical characteristics and living backgrounds on exercises were surveyed. The subjects were one-hundred and forty two girls(15~18 years, mean±SD=16.5±0.84 years) of a middle school in Nagano prefecture, accepted our visiting bone health check. Bone density was measured by ultrasound bone-densitometer 'Achilles'(Lunar). As for the data, we obtained the stiffness index(Stiffness) with a self-resistered questionnaire for the items of physical and exercise factors for the girls in puberty, middle school girls who belong to a sport club have significantly higher bone density than other girls. In detail, those who do the sports which consist of mainly running or jumping, have significantly higher bone density than others who do no sports. There also were significants on the kinds of sports, on the frequency of sports and on the duration of sports. Moreover, those who had the regular sports history have higher bone density than those who had no regular sports history, and the mean Stiffness of the group that care to do physical exercises daily was higher than those who do not care to do exercises. These results suggest that there are many kinds of factors related to sports which favourably contribute to obtain sufficient bone mass of middle school girls who are in a developmental stage.

내장형 시스템을 위한 재목적 링킹 로더

李大憲,禹德均,表昌祐 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-

In a development environment for embedded system with a connection between host and target system, the linking loader of host system links the cross-compiled object file and a modules of target system and downloads the linked object file to the target system. In this research, we separate this linking loader into the module dependent on object file format and the module independent on object file format. The dependent module gets the linking information independent of file format from the object file, and the independent module actually does the linking process with this linking information. We implemented the dependent module by using BFD library of GNU development environment, and this implementation can improve the portability of our linking loader for a new target system or object file format. Currently, we developed this linking loader in the embedded system development environment ESTO to be prepared for a commercial product.

만선신부전 환자에서 관상동맥조영술 소견에 관한 연구

한대희,김성구,박상호,김성한,조원영,방덕원,조윤행,정의룡,은영근,권영구 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Patients with chronic renal fialure have a substantially elevated risk of death from cardiovascular diseases than do the general population. the patients with chronic renal failure are at significantly increased freqeuncy of hypertension, hyperlipidemia, and diabetes mellitus which are known to the risk factors of the coronary artery diseases, and the prevalence of the coronary artery diseases in chronic renal failure patients is highly associated with the hemodynamic disorder and metabolic abnormalities. therefore we expected that the coronary angiographic findings in patients with chronic renal failure should be different from the general population (control groups) and investigated the risk factors contributing to coronary artery diseases. Method : we have retrospectively compared the coronary angiographic findings of 44 patients with chronic renal failure on hemodialysis with that of 88 patients in the general population and investigated the factors contributing to the development and acceleration of coronary artery diseases in patients with chronic renal failure Result : Hypertension and diabetes mellitus which is risk factors for coronary artery disease is significantly increased in patients with chronic renal failure, in coronary angiographic finding the severity of the lesion is worse. the incidence of PCI or CABG of patients with chronic renal failure is more than that of control group but statistically no difference between patients with chronic renal failure and control group. the sex, the duration of disease, the duration of dialysis, serum creatinine in patients with chronic renal failure have no correlation to the prevalence of coronary artery disease and severity of lesion. hyperglycemic patients with chronic renal failure have high incidence of coronary artery disease and are worse in the severity of lesion Conclusions : There is significantly increased the pevalence and severity of involving multiple coronary artery diseses in hyperglycemic patients with CRF.

활성화된 마우스 대식세포가 Toxoplasma gondii의 증식에 미치는 영향

엄대자,민득영,안명희 한양대학교 의과대학 1992 한양의대 학술지 Vol.12 No.1

The present study was aimed to elucidate the effect of antitoxoplasma activity and oxidative capacity of peritoneal macrophage of immunized and/or normal mouse. BALB/c mice were immunized with dozens of cyst (Beverly of Fukaya strain) intraperitoneally. Glass adherent cells were used as macrophage from immunized and normal mouse peritoneal cells. Macrophage(?? cells/ml) and Toxoplasma tachyzoite(RH strain) were incubated in 10% fetal calf serum-minimum essential medium, 37℃, 5% CO₂ incubator. The ratio of cell to Toxoplasma was 1:1 or 2:1. After 4 and 24hr incubation, cell rupture and infection rate of macrophage, number of tachyzoite in a cell were observed under microscope. Production of hydrogen peroxide from immunized or normal macrophage after 1hr incubation of Toxoplasma or Toxoplasma with phorbol myristate acetate(PMA) were measured. After 4hr incubation of macrophage and Toxoplasma tachyzoite, 10% of cell rupture were observed in normal and immunized macrophages. One to five organisms per cell were observed 32.8~38.7% of normal macrophage and 50.7~52.6% of immunized macrophages. After 24hr incubation, Toxoplasma multiply freely in normal mouse macrophage and 90% of cells were ruptured. Meanwhile immunized mouse macrophage display toxoplasmacidal effect and 50% of cells were survived. Toxoplasma invation into cell were 34.~48.7% of normal macrophage and 59.4% of immunized macrophage. Immunized macrophages released 2~7 times of H₂O₂than those of normal macrophages. With above results, it is assumed that peritoneal macrophage from immunized mouse has high producibility of H₂O₂and then might enhance the subsequential toxoplasmastatic and/or toxoplasmacidal effect.