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      • KCI등재

        국소 진행성 대장암에 대한 병합절제의 안전성에 대한 연구

        임대로 ( Dae Ro Lim ),홍영기 ( Young Ki Hong ),허호 ( Ho Huh ),임치영 ( Chi Young Lim ),강중구 ( Jung Gu Kang ),최윤정 ( Yoon Jung Choi ) 대한임상종양학회 2010 Korean Journal of Clinical Oncology Vol.6 No.2

        Purpose: About 10% of colorectal cancers are known to have already invaded contiguous organs or had inflammatory adhesion to adjacent structures. Under such circumstances, combined resections of involved structures may be considered. The aims of this study were to investigate true incidence of cancer invasion and surgical outcomes in patients where a multivisceral resection was performed for locally advanced colorectal cancer. Methods: Nine hundreds two patients with colorectal cancer submitted to surgical treatment between March 2000 and December 2007 were reviewed retrospectively, and multivisceral resection was performed in 68 patients. We reviewed the clinicopathologic characteristics of multivisceral resections for locally advanced colorectal cancer Results: The incidence of multivisceral resection was 7.5%. The positive predictive values of cancer invasion were 60.0% in CT and 57.1% in MRI. The rate of true cancer invasion in multivisceral resection was 46.4%. In TMN stage, stage IIIB was the most common (27.9%) and followed by stage IIIC (20.6%). Rectal cancer was 29 cases (42.6%), sigmoid colon cancer was 18 cases (26.4%). In combined resection, female reproductive organ were the most commonly involved organ (27.2%) and followed by small bowel (16.3%) and bladder (9.8%). In number of organs, one organ in the combined resection was 41 cases (60.3%) and there was 1 case in which 6 neighboring structure involved in combined resection. There was no postoperative death and complications in postoperative period occurred in 23.5% including wound infection, intestinal obstruction, and pneumonia. Conclusions: When adhesion to neighboring organ by primary colorectal cancer was found intraoperatively, multivisceral resection would be mandatory regardless of the preoperative assessment. Every effort to reduce postoperative complication may be necessary to justify multivisceral resection.

      • KCI등재

        Oncologic outcomes of squamous cell carcinoma of the anal canal after chemoradiation therapy

        Dae Ro Lim(임대로),Hyuk Hur(허혁),Byung Soh Min(민병소),Seung Hyuk Baik(백승혁),Kang Young Lee(이강영),Nam Kyu Kim(김남규) 대한종양외과학회 2016 Korean Journal of Clinical Oncology Vol.12 No.1

        Purpose: The aim of this study is to analyze the oncological outcomes of squamous cell carcinoma (SCC) of the anal canal after chemoradiation therapy (CRT) in a single institution. Methods: Fifty-one patients with anal SCC who had been treated with CRT between January 2000 and December 2010 were analyze data single center in Korea. Results: Forty-eight patients exhibited clinical complete response. After a median follow-up of 42.1 months, 13 patients (25.5%) showed recurrence. The disease-free survival (DFS) rate was 63.4% at 5 and 10 years. The overall survival (OS) rates were 83.6% (5 years) and 75.2% (10 years). Stage I: DFS, 100%; OS, 100%; stage II: DFS, 85.7%; OS, 100%; stage IIIA: DFS, 68.6%; OS, 87.5%; stage IIIB: DFS, 34.7%; OS, 48.4%; and stage IV: DFS and OS, 0%. The local recurrence patterns were as follows: pelvic node (n=4, 7.8%), inguinal node (n=1, 2.0%), and inguinal and pelvic node (n=1, 2.0%). The systemic recurrence patterns were as follows: lung (n=2, 3.9%), para-aortic node (n=1, 2.0%), and extrapelvic site (n=2, 3.9%). N-stage represented a single independent prognostic factor for recurrence (P<0.05). Conclusion: CRT for SCC of the anal canal is effective for oncological outcomes and sphincter preservation. The initial nodal status may affect the oncological outcome.

      • KCI등재

        Treatment of Squamous Cell Carcinoma of the Anal Margin : Single Center Experience

        Ji Young Yoo(유지영),Dae Ro Lim(임대로),Hyuk Hur(허혁),Byung Soh Min(민병소),Seung Hyuk Baik(백승혁),Kang Young Lee(이강영),Nam Kyu Kim(김남규) 대한종양외과학회 2012 Korean Journal of Clinical Oncology Vol.8 No.2

        목적 : 본 연구는 침생검을 통해 진단 받은 경화성 선증에 대해 추가적인 수술 없이 경과 관찰했을 때의 잠재적 안정성을 알아보고자 하였다. 방법 : 1996년 1월부터 2010년 5월까지 침생검을 통해 경화성 선증으로 진단된 143명의 환자의 145개 병변을 대상으로 (core-needle biopsies 118례, vacuum-assisted biopsies 27례) 의무기록 검토를 토대로 한 후향적 고찰이다. 결과 : 환자들의 BI-RADS(The American College of Radiology Breast Imaging Reporting and Data System) 분류는 다음과 같다: C3(n=8), C4a(n=123), C4b(n=11), C4c(n=e), C5(n=1). 그 중 14명은 조직검사를 재시행하였고 BI-RADS 분류 C5이면서 영상의학적 소견과 병리학적 소견의 불일치를 보인 1명의 환자가 침윤성 유방암으로 진단되어 수술을 시행하였다. 나머지 환자들은 정기적인 초음파 검사 및 유방촬영술을 통해 경과 관찰하였고, 평균 추적관찰 기간 40개월 동안 144개의 병변의 최종 BI-RADS 분류는 다음과 같다: C1(n=5), C2(n=107), C3(n=32), 경과 관찰기간 동안 142명의 환자에서 악성 유방질환이 발견된 환자는 없었다. 결론 : 침생검을 통해 경화성 선증으로 진단된 환자에 있어서 추가적인 수술 없이 정기적인 검진을 통하여 경과 관찰하는 것은 잠재적 안전성을 가지고 있다. 하지만 조직검사와 영상검사 결과의 불일치 소견을 보이는 경우 수술적 생검을 통한 최종 진단이 필요하다. Background : The aim of this study was to assess the potential safety of follow up for patients diagnosed with sclerosing adenosis through needle biopsies without additional surgery. Patients and Methods : From January 1996 to May 2010, 145 lesions in 143 sclerosing adenosis patients who underwent core-needle biopsies (n=118), vacuum-assisted biopsies (n=27) in our institution were followed. Results : The American College of Radiology Breast Imaging Reporting and Data System (BI-BADS) classification in these patients was as follows : C3(n=8), C4a(n=123), C4b(n=11), C4c(n=e) and C5(n=1). After sclerosing adenosis was diagnosed by needle biopsy, 14 patients underwent re-biopsy. Only 1 patient who had BIRAD C5 sonographic features was diagnosed with invasive ductal carcinoma and surrounding ductal carcinoma in situ. The remaining 142 patients received regular medical exam with ultrasonography and/or mammography. 144 lesions’ BI-RADS category were C1(n=5), C2(n=107) and C3(n=32). With the median follow-up period of 40 months, none of the patients developed breast malignancy. Conclusions : Our study suggest that patients with sclerosing adenosis diagnosed by needle biopsies can be safely followed without additional surgery. However, in case of discordance with images and biopsy result, surgical excision for definite diagnosis is recommended.

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