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Motivaciones de los estudiantes universitarios coreanos de ELE
Débora López Mata 한국스페인어문학회 2023 스페인어문학 Vol.- No.107
After years of research, it has been shown that the type of motivation that foreign language learners have towards the language directly influences their learning, from aspects ranging from language proficiency to the amount of time invested in studying it, and even the emotional development of the learner (Rabadán and Orgambídez, 2018; Nowakowska, 2020). Although, traditionally there has been talked of intrinsic and extrinsic motivation concepts, recent studies have also demonstrated the existence of so-called required motivation, especially in educational contexts in Asia (Gardner and Lambert, 1972; Gardner, 1979; Warden and Lin, 2000; Xu and Case, 2015). At the same time, despite Spanish being taught as a foreign language (ELE) in Korea for over 70 years in both university and school settings, there are still no studies on the reasons why Koreans decide to learn this language. Thus, this work aims to explore and analyze the motivations of university students studying ELE. In particular, it seeks to answer whether the required motivation is appreciated by this group. To this end, an online questionnaire was conducted among students from various Hispanic Philology departments in South Korea. Based on their responses, it was concluded that the main interest of these students is intrinsic motivation, followed by extrinsic and required motivation.
Débora Kestring,Luciana C. C. R. Menezes,Camila A. Tomaz,Giuseppina P. P. Lima,Marcelo N. Rossi 한국식물학회 2009 Journal of Plant Biology Vol.52 No.6
Phenolic contents were compared between Mimosa bimucronata seeds from infested and non-infested fruits to assess induced defense response. By measuring leg length of the bruchid beetle Acanthoscelides schrankiae, we verified whether phenolic contents affected bruchid body size. In addition, the relationship between physical seed traits and phenolic contents was examined. Results showed that seeds from infested fruits had significantly greater phenolic contents than seeds from non-infested fruits, which suggested induced defense. Body size variation in A. schrankiae was marginally nonsignificant according to phenolic contents among plants (negative trend), indicating that phenols may interfere directly with bruchid performance. Seeds that were more irregularly shaped had significantly greater phenolic contents than those that were more uniform. Therefore, the most perfectly spherical seeds may be more vulnerable to seed predation, and our results suggest that the production of phenolic compounds was increased in infested fruits, which in turn may affect A. schrankiae development.
Débora M.Borsato,Arthur S. Prudente,Patrícia M. Döll-Boscardin,Aurélio V. Borsato,Cynthia F.P. Luz,Beatriz H.L.N.S. Maia,Daniela A. Cabrini,Michel F. Otuki,Marilis D. Miguel,Paulo V. Farago,Obdulio G. 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.7
Melipona marginata is an endangered species of stingless bee from Brazil that produces honey with particular physicochemical features and a remarkable exotic flavor. To the best of our knowledge, this is the first report devoted to exploring the medicinal potential of this honey. Thus, the aim of this paper was to investigate the potential anti-inflammatory activity of honey extract from M. marginata on skin inflammation. The honey sample was classified as a monofloral honey of Mimosa scabrella. The presence of 11 phenolic compounds as kaempferol and caffeic acid was detected using the highperformance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-UV-ESI-MS) method. The anti-inflammatory activity was measured using a 12-O-tetradecanoylphorbol-13-acetate-induced ear edema model of inflammation in mice. The topical application of the M. marginata honey extract (1.0 mg/ear) was able to reduce ear edema with an inhibitory effect of 54 – 5%. This extract decreased the myeloperoxidase activity in 75 – 3%, which suggests a lower leucocyte infiltration that was confirmed by histological analysis. This extract also provided a reduction of 55 – 14% in the production of reactive oxygen species. This anti-inflammatory activity could be due to a synergic effect of the phenolic compounds identified in the honey sample. Taken together, these results open up new possibilities for the use of M. marginata honey extract in skin disorders.
Débora Figlas,Micaela Oddera,Ne´stor Curvetto 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.2
Grifola frondosa is an edible and medicinal mushroom. The bioaccumulation and potential biovailability of Cu and Zn were studied to obtain mycelium with potential properties as a food dietary supplement. Mycelia grown in the presence of nonmycotoxic concentrations of 100 and 200ppm of Cu or 25 and 50ppm of Zn accumulated 200–322ppm and 267–510ppm of Cu or Zn, respectively. When these enriched metal mycelia were subjected in vitro to a simulated gastrointestinal digestion, the solubility in these digestive fluids was 642–669ppm and 102–530ppm, which represent 32–33% and 0.7–3.5% of the recommended daily intake (RDI) for Cu and Zn, respectively, in 1g of mycelium. These results are discussed in relation to the RDI values exhibited by two commercial supplements, and arguments are given on the potential use of these mineral-enriched mycelia in capsules (in the case of Cu-enriched mycelia), in food preparations, and also as a component of cosmetic mixtures.
Brain Neuroplasticity after Treatment with Antiseizure: A Review
Débora Lopes Silva de Souza,Hosana Mirelle Goes e Silva Costa,Francisca Idalina Neta,Paulo Leonardo Araujo de Gois Morais,Luís Marcos de Medeiros Guerra,Fausto Pierdoná Guzen,Lucídio Clebeson de Olive 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.4
Epilepsy is a disease characterized by the periodic occurrence of seizures. Seizures can be controlled by antiseizure medications, which can improve the lives of individuals with epilepsy when given proper treatment. Therefore, this study aimed to review the scientific literature on brain neuroplasticity after treatment with antiseizure drugs in different regions of the brain. According to the findings, that several antiseizure, such as lamotrigine, diazepam, levetiracetam, and valproic acid, in addition to controlling seizures, can also act on neuroplasticity in different brain regions. The study of this topic becomes important, as it will help to understand the neuroplastic mechanisms of these drugs, in addition to helping to improve the effectiveness of these drugs in controlling the disease.
Cissus sicyoides: Analysis of Glycemic Control in Diabetic Rats Through Biomarkers
Jocelem Mastrodi Salgado,Débora Niero Mansi,Antonio Gagliardi 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.4
Diabetes is a chronic degenerative disease with no cure, is found in millions of people worldwide, and can cause life-threatening complications at any age. The plant Cissus sicyoides L. is a runner plant found abundantly in Brazil, especially in the Amazon. Its therapeutic properties are widely used in popular medicine as a diuretic, anti-influenza, anti-inflammatory, anticonvulsion, and hypoglycemic agent. The objective of this study was to analyze the effects of aqueous extracts from the leaves and stem of C. sicyoides L., administered for 60 days, for the control of glycemia in alloxan (monohydrate)-induced diabetic rats, monitored by biomarkers. Data obtained in this study confirmed that C. sicyoides has a hypoglycemic effect on diabetic rats. Administration of its aqueous extracts promoted a 45% decrease in glucose levels after 60 days of administration. Furthermore, indices of hepatic glycogen, blood glucose, C-reactive peptide, and fructosamine were found to be efficient biomarkers to monitor diabetes in rats.
Bárbara Jaime dos Santos,Débora Balabram,Virginia Mara Reis Gomes,Carolina Costa Café de Castro,Paulo Henrique Costa Diniz,Marcelo Araújo Buzelin,Cristiana Buzelin Nunes 대한암학회 2024 Cancer Research and Treatment Vol.56 No.1
Purpose Neoadjuvant chemotherapy (NACT) can change invasive breast carcinomas (IBC) and influence the patients’ overall survival time (OS). We aimed to identify IBC changes after NACT and their association with OS.Materials and Methods IBC data in pre- and post-NACT samples of 86 patients were evaluated and associated with OS.Results Post-NACT tumors changed nuclear pleomorphism score (p=0.025); mitotic count (p=0.002); % of tumor-infiltrating inflammatory cells (p=0.016); presence of <i>in situ</i> carcinoma (p=0.001) and lymphovascular invasion (LVI; p=0.002); expression of estrogen (p=0.003), progesterone receptors (PR; p=0.019), and Ki67 (p=0.003). Immunohistochemical (IHC) profile changed in 26 tumors (30.2%, p=0.050). Higher risk of death was significatively associated with initial tumor histological grade III (hazard ratio [HR], 2.94), high nuclear pleomorphism (HR, 2.53), high Ki67 index (HR, 2.47), post-NACT presence of LVI (HR, 1.90), luminal B–like profile (HR, 2.58), pre- (HR, 2.26) and post-NACT intermediate mitotic count (HR, 2.12), pre- (HR, 4.45) and post-NACT triple-negative IHC profile (HR, 4.52). On the other hand, lower risk of death was significative associated with pre- (HR, 0.35) and post-NACT (HR, 0.39) estrogen receptor–positive, and pre- (HR, 0.37) and post-NACT (HR, 0.57) PR-positive. Changes in IHC profile were associated with longer OS (p=0.050). In multivariate analysis, pre-NACT grade III tumors and pre-NACT and post-NACT triple negative IHC profile proved to be independent factors for shorter OS.Conclusion NACT can change tumor characteristics and biomarkers and impact on OS; therefore, they should be reassessed on residual samples to improve therapeutic decisions.
Artur N. Carreiro,João A. R. A. Diniz,Joyce G. Souza,Débora V. F. Araújo,Rômulo F. F. Dias,Liliane M. S. Azerêdo,Ediane F. Rocha,Ana Y. F. La Salles,Carlos E. Peña-Alfaro,Maria A. M. Carvalho,Maria J. 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.3
The objective of the present study was to monitor and characterize morphological alterations in ovaries of agouti (Dasyprocta prymnolopha), reared in captivity, by using abdominal ultrasonography. All animals underwent daily vaginal cytological examination to identify the current cycle phase. For each phase of the estrous cycle, ultrasound examinations were carried out to identify and describe the morphology of both ovaries. Topographic parameters in an ultrasound window were established to locate the ovaries. The agouti estrous cycle lasted an average of 29.94 ± 6.77 days. During vaginal cytology examinations, all cell types were identified, and each phase of the estrous cycle was established by cell counts. No significant alterations were observed in the assessed ovarian morphometry measurements. In 75% of the animals examined, ovarian follicle presence was observed in the proestrus phase.
Cytogenotoxic study of aqueous fruit extract of Morinda citrifolia in Wistar albino rats
Germano Pinho de Moraes,Marcus Vinícius Oliveira Barros de Alencar,Lidiane da Silva Araújo,Débora Cássia Vieira Gomes,Márcia Fernanda Correia Jardim Paz,Muhammad Torequl Islam,Ana Amélia de Carvalho M 경희대학교 융합한의과학연구소 2019 Oriental Pharmacy and Experimental Medicine Vol.19 No.3
The use of herbal products and/or their derivatives as an alternative or complementary medicine becomes globally popular. To date, various biological activities have been reported in Morinda citrifolia Linn, especially antioxidants, antimicrobial, anti-infammatory and antitumor efects. This study aimed to investigate the genotoxicity and DNA repair capacity of the aqueous fruit extract of M. citrifolia (AEMC). Additionally, we checked the mutagenic capacity of AEMC by the comet assay and micronucleus tests in rats. For this, rats (n=10; 5 males and 5 females) were divided into fve groups as: negative control (distilled water); positive control (25 mg/kg of cyclophosphamide, i.p.); and three groups for AEMC (2.5, 5 and 10 mg/kg, i.p.). The results suggest that, the AEMC induced genotoxicity in white blood cells, but a DNA repair capacity was also observed after 72 h of AEMC exposure. AEMC also showed cytotoxicity and mutagenicity in liver and kidney cells of rats at 5 and 10 mg/kg doses. In conclusion, AEMC exhibited a dose-dependent cytotoxicity, genotoxicity and mutagenicity along with a time-dependent DNA repair capacity in rats. Further studies are necessary regarding the safe use of this medicinal plant for human consumption.
Priscila Vaz de Arruda,Júlio César dos Santos,Rita de Cássia Lacerda Brambilla Rodrigues,Débora Danielle Virgínio da Silva,Celina Kiyomi Yamakawa,George Jackson de Moraes Rocha,Jonas Nolasco Júnior,Jo 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.47 No.-
In this study, volumetric oxygen mass transfer coefficient (kLa) was selected as a criterion for facilitatingthe scale up of xylitol production by Candida guilliermondii at the bench and pilot-scale level. A kLa valueof 16 h 1 was applied in reactors with volumetric capacity of 2.4 L, 18 L and 125 L. Fermentation wassuccessfully scaled-up from the bench to pilot-scale level with all experiments demonstrating aminimum of 60% xylose to xylitol conversion efficiency. Under all evaluated conditions glycerol andethanol were also produced as by-products of xylose metabolism. Only minor differences were observedin the fermentation profile when reactor volumes ranging from 2.4 L to 125 L were used forexperimentation purposes, reaching, at pilot scale, yield and volumetric productivity of 0.55 g g 1and 0.31 g L 1 h 1, respectively, with maximum specific growth rate of 0.26 h 1. This demonstrates andreinforces the feasibility of using kLa as scale up criterion. The use of this parameter allowed precisereproduction of results obtained at bench bioreactor level to a larger scale; this is extremely crucial andimportant information considering that the aim of the proposed biotechnological process is to reach thelevel required for the industrial viability.