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현웅근,유춘식 호남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.8 No.-
A wireless communication module for multiple PLC was developed. The function of the developed system are dual communication , concurrent multiple communication, PLC control ,d interpretation of PLC command, and A/D D/A converting. The multiple communication approach Is based on master-slave control concept. To show validity of the developed module, severial experiments are illustrated.
최춘길,하웅의 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1
The purpose of this study was to investigate the variables relating to the incidence and copying strategies of taekwondo athletic injury. The subjects were taekwnondo athletic(n=40) from K university. In The method of this study, athletic injury questionnaire was designed for the purpose of this study researcher. The selected variables relating to the incidence of athletic injury of this study were training game process variable, game boundary. The conclusions and implications of this study were as follows : The variables relating to the injure incidence of taekwondo player were lack of skill and strategy(47.5%), training too hard(42.5%), lack of basis physical ability(35%) in training, game process variables, physical fatigue(77.5%), indifference of warm-up, cooling down (62.5%), individual mistake(30%). In boundary variables were exceed tention(32.5%), lack of self-confidence(30%), high anxiety(25%).
광학 시스템을 이용한 Gantry Stage의 열변형 오차를 고려한 실시간 보상 실험
조웅,송춘삼,김종형 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-
This paper suggests method to measure that error of the precision stage is used precision process and measurement equipment by using camera optics. The laser interferometer is the most widely used sensing unit to measure the position error. It measures the positioning error from the displacement of a moving reflector in terms of the wave length. But, the wave length os affected by the variation of atmospheric temperature. Temperature variation of 1℃ results in the measuring error of 1ppm. Though laser interferometer measures position error of stage when precision stage is manufactured by us or it is used to measure stage for the nonce as a general rule, optics tooling position measurement method to suggest is possible to apply in real-time and trace an error range continually. Therefore it is able to improve capabilities of equipment by compensating an error range when operates precision process and measurement equipment in real-time. From the experiment, it is confirmed that the measuring error of the optical device can be improved from 5.8㎛ to 1㎛ by the application of the method.
Analysis of the Apoptotic Mechanisms of Snake Venom Toxin on Inflammation-induced HaCaT Cell-line
Chun, Youl Woong,Song, Ho Sueb Korean AcupunctureMoxibustion Medicine Society 2017 대한침구의학회지 Vol.27 No.6
Objectives : In this study, the roles of Interleukin (IL)-4 and Signal transducer and activator of transcription 6 (STAT6), which have been reported to play a role in the pathogenesis of inflammation and cancer, were evaluated in snake venom toxin (SVT)-induced apoptosis. Methods : Inflammation was induced in human HaCaT kerationocytes, by lipopolysaccharide (LPS; $1{\mu}g/mL$) or tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), followed by treatment with SVT (0, 1, or $2{\mu}g/mL$). Cell viability was assessed by MTT assays after 24 h, and the expression of levels of IL-4, STAT6, and the apoptosis-related proteins p53, Bax, and Bcl-2 were evaluated by western blotting. Electro mobility shift assays (EMSAs) were performed to evaluate the DNA binding capacity of STAT6. Results : MTT assays showed that inflammation-induced growth of HaCaT cells following LPS or TNF-${\alpha}$ stimulation was inhibited by SVT. Western blot analysis showed that p53 and Bax, which promote apoptosis, were increased, whereas that of Bcl-2, an anti-apoptotic protein, was decreased in a concentration-dependent manner in LPS- or TNF-${\alpha}$-induced HaCaT cells following treatment with SVT. Moreover, following treatment of HaCaT cells with LPS, IL-4 concentrations were increased, and treatment with SVT further increased IL-4 expression in a concentration-dependent manner. Western blotting and EMSAs showed that the phosphorylated form of STAT6 was increased in HaCaT cells in the context of LPS- or TNF-${\alpha}$-induced inflammation in a concentration-dependent manner, concomitant with an increase in the DNA binding activity of STAT6. Conclusion : SVT can effectively promote apoptosis in HaCaT cells in the presence of inflammation through a pathway involving IL-4 and STAT6.
Extraforaminal Extrusion of Intervertebral Disc Misdiagnosed as Neurogenic Tumor: a Case Report
Chun, Se-Woong,Park, Young-Seop,Heo, Won,Baek, Kyeonghee,Moon, Jin Il Korean Society of Magnetic Resonance in Medicine 2017 Investigative Magnetic Resonance Imaging Vol.21 No.2
A 55-year-old male presented with dysesthesia of the right anteromedial thigh. A magnetic resonance image revealed a globular mass at the right extraforaminal area of the L3/4 level. Based on the diagnosis of neurogenic tumor, surgical excision was performed. The surgical impression and pathology confirmed extrusion of intervertebral disc. In a retrospective review of the magnetic resonance image, we noticed a fibrillary pattern directed from the intervertebral disc space to the lesion, and disrupted annulus fibrosus and indentation caused by the ring apophysis. We suggest aforementioned features, indicative of intervertebral disc lesions, to be checked when interpreting mass lesions around the intervertebral foramen.
Scaling Down Characteristics of Vertical Channel Phase Change Random Access Memory (VPCRAM)
Chun Woong Park,Chongdae Park,Woo Young Choi,Dongsun Seo,Cherlhyun Jeong,Il Hwan Cho 대한전자공학회 2014 Journal of semiconductor technology and science Vol.14 No.1
In this paper, scaling down characteristics of vertical channel phase random access memory are investigated with device simulator and finite element analysis simulator. Electrical properties of select transistor are obtained by device simulator and those of phase change material are obtained by finite element analysis simulator. From the fusion of both data, scaling properties of vertical channel phase change random access memory (VPCRAM) are considered with ITRS roadmap. Simulation of set reset current are carried out to analyze the feasibility of scaling down and compared with values in ITRS roadmap. Simulation results show that width and length ratio of the phase change material (PCM) is key parameter of scaling down in VPCRAM. Thermal simulation results provide the design guideline of VPCRAM. Optimization of phase change material in VPCRAM can be achieved by oxide sidewall process optimization.
Preparation and in vivo evaluation of immediate-release pellet containing celecoxib solid dispersion
Chun-Woong Park,Nguyen-Thach Tung,Dao-Danh Son,김주영,이윤석,Seung-Yeop Kang,Shin-Ae Park,황규목,오택운,하정명,Sang-Cheol Chi,박은석 한국약제학회 2012 Journal of Pharmaceutical Investigation Vol.42 No.3
The aim of this study was to make use of small size of immediate-release (IR) pellet and amorphous state of solid dispersion to increase solubility of celecoxib (CLX), a drug in BCS class II. Primary, binary and ternary solid dispersions were developed to choose the final components for solid dispersion. A ternary novel solid dispersion was prepared by incorporation of one aqueous soluble polymer (povidone k17; PVP 17PF), Methacrylate copolymer-based gastric soluble polymer (Eudragit EPO) and one pH modulator (MgO). This combination was effective to increase solubility in pH 1.2 up to 25–30 %. The mechanismof solubility enhancement was proven by DSC, PRXD, and FT-IR. Accordingly, hydrogen bonding or electrostatic interaction of CLXwithPVP/EudragitEPOwas themain cause to formthe amorphous state of CLX within polymer cluster which increasing solubility of drug. Besides, MgO played an important role to change microenviroment for solid dispersion. Pellets containing this solid dispersion were prepared by extrusion and spheronization technique. Effect of four kinds of additive (calciumhydrogen phosphate dihydrate,NaHCO3,crospovidone, and sodium dodecyl sulfate) on dissolution of CLX from IR pellet was also determined. Because of highest dissolution rate, formulation using sodium dodecyl sulfate was used for pharmacokinetics study. Solid dispersion-IR pellet formulation presented bioequivalence and lower variability in comparison with reference product.