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Polyethylene Glycol과 Dextran이 포함된 고분자 수용액의 액-액 상평형
조정모,강춘형 전남대학교 촉매연구소 2000 觸媒硏究 論文集 Vol.21 No.-
The extraction using an aqueous two-phase polymer solution (ATPS) is a promising technique for separation of biologically active materials. Since ATPS contains mainly water, it provides a mild environment to the biological materials so that their biological activities can be preserved during the process. Among the factors that influence the phase behavior of ATPS, the molecular weight distributions(MWD) of the phase forming polymers have long been ignored. With special attention to the effects of MWD of the polymers, the liquid-liquid equilibrium(LLE) phase diagrams of ATPS containing polyethylene glycol(PEG) and dextrin(Dex) are experimentally determined using the gel permeation chromatography(GPC) and the polymer fractionation in the phase separation is observed. Namely, we observe that the MWDs of both polymers in the coexisting phases are different from each other as well as from the original distribution. Furthermore it is found that while the average molecular weight of Dex in the top phase decreases with the increase of the tie-line length(TLL), that of the bottom phase asymptotically approaches that of the original. The continuous dilution method is examined for the complete determination of the phase diagrams.
무증상의 후두개곡 낭종 환자에서 예기치 못한 어려운 기관내 삽관 1례
이상모,최준석,이철승,김원태,박천희 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Although vallecular cyst is often asymptomatic and harmless to the patient, discovery of large vallecular cyst after induction of anesthesia is a potentially life-threatening problem for thepatient and provides for the anesthesiologist a challenge in airway management. We describe a case of difficult intubation where the laryngeal inlet was obscured by a large vallecular cyst that was discovered during induction of general anesthesia. A 47-year-old man presented for elective laparoscopic colecystectomy due to GB polyp. He had normal mouth opening and neck extension; no mass or distortions of the tongue or neck were observed. Anesthesia and paralysis were induced with 80 ㎎ propofol, alfentanil 0.5 ㎎, midazolam 2.0 ㎎ and rocuromum 50 ㎎. It was noted that ventilation of the lungs via mask was difficult. Despite insertion of an oropharyngeal airway, ventilation proved to be more difficult. Intubation was attempted. Direct laryngoscopy (Macintosh 3 blade) revealed a 3-4 ㎝ tranlucent cyst arising from the left vallecula. The cyst completely obscured the view of epiglottis and vocal cords, preventing intubation despite multiple attempts by three anesthesiologists. StafF anesthesiologist was aspirated cyst using a 16-guage needle, syringe and 20 ㎖ of serous fluid were aspirated from cyst. The epiglottis and vocal cord were then exposed and tracheal intubation was performed easily with a size 7.0 cuffed oral tracheal tube. Anesthesia and the operation then proceeded uneventfully, following laparoscopic colecystectomy, an ENT surgeon removed the cyst.
Dextran-based Hydrogel의 제조 및 특성에 관한 연구
조정모,노선균,강춘형 전남대학교 촉매연구소 2001 觸媒硏究 論文集 Vol.22 No.-
Due to their sensitivity to external condition, adjustable permeability and high water content, hydrogels have widespread applications in medical, pharmaceutical, biochemical and other industrial fields. In this work, the dextran-based hydrogel was prepared by derivatization of polysaccharide with methacryloyl groups followed by polymerization of an aqueous solution of this methacrylated dextral(dex-MA) in presence of an initiator system consisting of potassium peroxydisulfate(KPS ) and N,N,N',N'-tetramethylethylene diamine(TEMED). The hydrogel and dex-MA thus prepared were characterized by 1H NMR, 13C NMR, FT-IR, and gel permeation chromatography(GPC). Degrees of substitution of MA groups in the glucopyranosyl ring(DS) estimated from peak intensities in 1H NMR spectra were found to be comparable with the prescribed values. Furthermore, the liquid-liquid equilibrium(LLE) phase diagrams of dex-MA/poly (ethylene glycol) (PEG)/water systems at 25℃ were experimentally determined for several dex-MAs of different DS. Finally, the swelling behavior of the hydrogels prepared with dex-MA of different DS was characterized by means of the blue-dex solution method as well as the gravimetric method.
Robert N. Bellah의 일본의 종교분석과 문화적 Identity의 현재적 의의
남춘모 대구효성카돌릭대학교사회과학연구소 1999 사회과학연구 Vol.6 No.-
The purpose of this study is to understanding Robert N. Bellah’s prospect and analysis frame as a religious sociologist, to appreciate his analysis to the relation of Japanese religion to modernization, and to grasp the meaning of his Cultural Identity. First of all, this study will get us to understanding the system of traditional value in Japanese society and particularity of Japanese culture. And by grasping the meaning of Cultural identity, we will recognize the true value of religion in modern society and become awake of the necessity of the sociological study of religion as a constituent element of social system
박치영,모성환,문철호,곽재정,김태종,전용준,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1995 The Medical Journal of Chosun University Vol.20 No.2
von Willebrand's disease (vWD) is the most common autosomal-dominant inherited disorder resulting from a quantitative or a qualitative defect of von Willebrand factor (vWF). The most diagnostic pattern is the combination of a prolonged bleeding time, a reduction in plasma vWF concentration, a parallel reduction in ristocetin cofactor activity, and reduced factor Ⅷ activity, In this case, ristocetin-induced platelet aggregation data were compatible with that of vWD. Bleeding times were prolonged over 4 minutes, vWF antigen levels were 45%. vWF ristocetin cofactor activities were 0~1% and factor Ⅷ levels were 31%, when compared to the normal control. We report the case of a family with vWD. characterized by a quantitative defect in vWF
기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1
Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.