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Yu, Shun-Jen,Lee, Yi-Hao,Lin, Ching-Ping,Wu, Aaron Yu-Jen Korean Academy of Periodontology 2019 Journal of Periodontal & Implant Science Vol.49 No.4
Purpose: To analyze the maxillary sinus anatomy over edentulous ridges in the bilateral posterior maxillary area in Taiwanese patients using cone-beam computed tomography (CBCT). Methods: In total, 101 anatomical sites from 61 patients, including 32 premolar and 69 molar regions, were analyzed using CBCT. Measurements were made of the width and height of edentulous ridges, the thickness of the lateral wall of the maxillary sinus, and the presence of a sinus septum and the posterior superior alveolar artery (PSAA). A statistical analysis of the measurements was performed, and correlations among the measurements were assessed. Results: The average ridge width was $10.26{\pm}3.16mm$, with a significantly greater ridge width in the second molar region than in the premolar region. The mean residual ridge height was $8.55{\pm}4.09mm$, and ridge height showed an opposite trend from ridge width for the premolar and molar regions. A sinus septum was present at 5.9% of the sites, and the PSAA was observed in 24.5%. The average thickness of the lateral wall of the maxillary sinus was $2.08{\pm}0.94mm$, with no significant difference between the tooth position and lateral wall thickness. Conclusions: This study presents the anatomical features of the maxillary sinus, which should be considered in sinus lift procedures for implant placement, in the Taiwanese population. The use of CBCT is recommended to avoid intraoperative complications.
Yu-Hsiang Juan,Sachin S. Saboo,Vishal Anand,Yiannis S. Chatzizisis,Yu-Ching Lin,Michael L. Steigner 대한영상의학회 2014 Korean Journal of Radiology Vol.15 No.2
Superior vena cava (SVC) obstruction is associated with the gradual development of venous collaterals. We present a rare form of systemic-to-pulmonary subpleural collateral pathway that developed in the bridging subpleural pulmonary veins in a 54-year-old woman with complete SVC obstruction. This uncommon collateral pathway represents a rare form of acquired right-to-left shunt due to previous pleural adhesions with an increased risk of stroke due to right-to-left venous shunting, which requires lifelong anticoagulation.
High-Quality and Robust Reversible Data Hiding by Coefficient Shifting Algorithm
Ching-Yu Yang,Chih-Hung Lin 한국전자통신연구원 2012 ETRI Journal Vol.34 No.3
This study presents two reversible data hiding schemes based on the coefficient shifting (CS) algorithm. The first scheme uses the CS algorithm with a mean predictor in the spatial domain to provide a large payload while minimizing distortion. To guard against manipulations,the second scheme uses a robust version of the CS algorithm with feature embedding implemented in the integer wavelet transform domain. Simulations demonstrate that both the payload and peak signal-tonoise ratio generated by the CS algorithm with a mean predictor are better than those generated by existing techniques. In addition, the marked images generated by the variant of the CS algorithm are robust to various manipulations created by JPEG2000 compression, JPEG compression, noise additions, (edge) sharpening, low-pass filtering, bit truncation, brightness, contrast, (color)quantization, winding, zigzag and poster edge distortion,and inversion.
Robust Watermarking Scheme Based on Radius Weight Mean and Feature-Embedding Technique
Ching-Yu Yang 한국전자통신연구원 2013 ETRI Journal Vol.35 No.3
In this paper, the radius weight mean (RWM) and the feature-embedding technique are used to present a novel watermarking scheme for color images. Simulations validate that the stego-images generated by the proposed scheme are robust against most common image-processing operations, such as compression, color quantization, bit truncation, noise addition, cropping, blurring, mosaicking, zigzagging, inversion, (edge) sharpening, and so on. The proposed method possesses outstanding performance in resisting high compression ratio attacks: JPEG2000 and JPEG. Further, to provide extra hiding storage, a steganographic method using the RWM with the least significant bit substitution technique is suggested. Experiment results indicate that the resulting perceived quality is desirable, whereas the peak signal-to-noise ratio is high. The payload generated using the proposed method is also superior to that generated by existing approaches.
High-Performance Reversible Data Hiding with Overflow/Underflow Avoidance
Ching-Yu Yang,Wu-Chih Hu 한국전자통신연구원 2011 ETRI Journal Vol.33 No.4
This paper proposes reversible data hiding using minimum/maximum preserved overflow/underflow avoidance (MMPOUA). The proposed MMPOUA algorithm consists of three main steps. These steps include the minimum (or maximum) pixel fixing, pixel squeezing, and pixel isolation. The aims of pixel fixing are to keep the minimum (or maximum) pixel of a host block unchanged and prevent the occurrence of overflow/underflow. Both the pixel squeezing and pixel isolation supply hiding storage while keeping the amount of distortion low. The proposed method can avoid (or significantly reduce) the overhead bits used to overcome overflow/underflow issues. At an embedding rate of 0.15 bpp, the proposed algorithm can achieve a PSNR value of 48.52 dB, which outperforms several existing reversible data hiding schemes. Furthermore, the algorithm performed well in a variety of images, including those in which other algorithms had difficulty obtaining good hiding storage with high perceived quality.
Yu, Ching-Hsin Center for Asian Public Opinion Research Collabora 2013 Asian journal for public opinion research Vol.1 No.1
In 2008, Taiwan adopted a new mixed member system which is significantly different from the long-implemented SNTV-MMD system for the election of legislators. The new system cuts the number of legislative seats from 225 to 113, extends legislators' terms of office from three years to four, and most importantly, adopts a new mixed-member majoritarian (MMM) electoral system to replace the SNTV system for legislative elections. The election of legislators in 2008 was the first time that this new mixed electoral system was implemented in Taiwan. Mainstream literature continues to discuss the electoral impact on political parties and candidates by the new system while citizens' knowledge of the new system and its concomitant effects on citizens' behavior receive less attention. Worse still, almost all of the literature assumes that voters were fully aware of the operation and impact of the new electoral system and cast their ballots wisely. The purpose of this paper is to explore citizen's perceptions, participation and evaluation of this new system.
( Ching-ling Lin ),( Ming-lin Tsai ),( Yu-hsin Chen ),( Wei-ni Liu ),( Chun-yu Lin ),( Kai-wen Hsu ),( Chien-yu Huang ),( Yu-jia Chang ),( Po-li Wei ),( Shu-huey Chen ),( Li-chi Huang ),( Chia-hwa Lee 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.5
Thyroid cancer is the most common endocrine malignancy. Patients with well-differentiated thyroid cancers, such as papillary and follicular cancers, have a favorable prognosis. However, poorly differentiated thyroid cancers, such as medullary, squamous and anaplastic advanced thyroid cancers, are very aggressive and insensitive to radioiodine treatment. Thus, novel therapies that attenuate metastasis are urgently needed. We found that both PDGFC and PDGFRA are predominantly expressed in thyroid cancers and that the survival rate is significantly lower in patients with high PDGFRA expression. This finding indicates the important role of PDGF/PDGFR signaling in thyroid cancer development. Next, we established a SW579 squamous thyroid cancer cell line with 95.6% PDGFRA gene insertion and deletions (indels) through CRISPR/Cas9. Protein and invasion analysis showed a dramatic loss in EMT marker expression and metastatic ability. Furthermore, xenograft tumors derived from PDGFRA geneedited SW579 cells exhibited a minor decrease in tumor growth. However, distant lung metastasis was completely abolished upon PDGFRA gene editing, implying that PDGFRA could be an effective target to inhibit distant metastasis in advanced thyroid cancers. To translate this finding to the clinic, we used the most relevant multikinase inhibitor, imatinib, to inhibit PDGFRA signaling. The results showed that imatinib significantly suppressed cell growth, induced cell cycle arrest and cell death in SW579 cells. Our developed noninvasive apoptosis detection sensor (NIADS) indicated that imatinib induced cell apoptosis through caspase-3 activation. In conclusion, we believe that developing a specific and selective targeted therapy for PDGFRA would effectively suppress PDGFRA-mediated cancer aggressiveness in advanced thyroid cancers.