水原市 近郊 光橋山의 植物相 (Ⅱ)

姜佑昌,張珍成,張桂羨,金輝,金正猷 서울大學校農業生命科學大學附屬樹木園 2002 서울大學校 樹木園 硏究報告 Vol.- No.22

광교산 지역의 일반식물상을 밝히고 기존의 자료와 비교하여 광교산의 정밀한 식물상에 대한 정보를 구축하며 또 광교산에서 자생하고 있는 특정식물의 분포지역을 파악하기 위해서 식물상 조사를 실시하였다. 조사는 총 7개 경로로 실시하였으며 조사지역내에 1㎞×1㎞의 격자를 34개 설치하여 각 격자내에서 정밀한 식생을 파악 하였다. 조사결과 광교산에는 46과 76속 95종류의 식물이 자생하는 것으로 확인되었으며 분비나무, 귀룽나무, 고로쇠, 산돌배 등 환경부의 특정식물종 4 종이 확인되어 이들이 서식하는 C1, E4, E5, F3,와 F4의 5개 지역은 특별한 관리가 필요한 것으로 생각된다. 금번조사 결과와 기존의 조사결과를 종합한 결과 기존에 광교산에 자생하는 것으로 알려진 히어리의 자생상태는 확인할 수 없어 보다 세밀한 조사가 필요하다. Mt. Gwanggyo and adjacent regions were revisited to study flora based on pinpoint collection data(GPS) as well as to inventory rare and endangered plants. Thirty four meshes and seven routes were established to make a decision for the conservation priority. During the exploration, we find 46 families, 76 genera and 95 taxa (including species, subspecies, varieties, and forma). There were five prior species, Abies nephrolepis, Prunus padus, Cornus controvera, Acer pictum var. mono, and Pyrus ussuriensis, which were the 3rd level of conservation priority. According to conservation priority, five meshes, C1, E4, E5, F3, and F4 were core areas to be protected. In the course of study, we were not able to find more individuals of Corylopsis glabrescens var. gotoana except four individuals in 1992 study.

NATM 터널 굴착시 불연속면을 고려한 터널주위의 변형거동 연구

강추원,유기정,고진석 조선대학교 에너지.자원신기술연구소 2003 에너지·자원신기술연구소 논문지 Vol.25 No.1

In-situ rock mass includes discontinuity such as faults, joints and fracture zone, and underground structure and tunnel within them have some different behavior according to the geometric form and the mechanics properties of discontinuity. It is desirable to consider the effects of discontinuity in designing and constructing the underground structure and the tunnel. Therefore in this study the interface element in finite different program which is one of the continuum modeling was used to effectively reflect the properties of discontinuity. The stability of tunnel would be understanded by analyzing the deformation behavior of around the tunnel with the model for rock mass considering discontinuity. There are some result from this study by FDM analysis considering the discontinuity. It was found that there would be stable state because the convergence analysis was so small. The principle stress had the asymmetry to the vertical axis of tunnel due to the discontinuity. The shotcrete stresses proved to be under the allowable value and the rock bolt axial forces were below the design strength as 10 ton.

제대 및 신생아 혈중 cytokine(IL₁β, IL6, TNF) 수치의 변화

강진무,김홍식,박인식,이형종 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

분만방법에 따른 제대혈과 양수 그리고 감염 및 stress가 있는 신생아혈중과 세포성분을 배양한 상청액의 cytokine치를 ELISA법으로 측정하여 다음과 같은 성적을 얻었다. 제대혈중 IL₁β치는 질식 유도분만때가 질식 자연 분만, 응급 제왕절개 및 계획 제왕절개때보다 유의하게 높았다(p<0.001). 신생아 혈중 IL₁β치는 감염이 동반된 경우와 stress가 동반된 경우에 높았으며, 감염이 동반되었을 때가 stress보다 더 높게 나타났고, 저체중 출생아에서 높았다. 계획 제왕절개시의 제대혈 IL₁β치는 양수보다 낮았다. 질식자연 분만시 제대혈 세포상청액의 IL₁β 혈장치보다 높았고, 양자간에 유의한 상관관계를 보였다(r=0.92, p<0.05). 감염이 동반된 신생아에서 IL₁β치는 혈장치가 높은 경우 세포 상청액치는 낮고, 혈장치가 낮은 경우 세포 상청액치는 높았다. IL6는 감염이 있는 신생아 혈장과 세포 상청액, 양수 등에서 검출되었다. TNF는 감염이 있는 신생아 세포 상청액 8례중 3례에서 측정되었다 The cytokines, interleukin-1β(IL₁β), interleukin-6(IL6) and tumor necrosis factor(TNF) are important mediators of host response to stress and infection. Impaired immune reaction and febrile responses to the infection in newborn period may result from abnormal cytokine regulation and there were difference in the responses between newborn and adult due to the different cytokine regulation system. To investigate the cytokine regulation in different circumstances of the delivery and newborn conditions, the measurement of the levels of IL₁β,IL6 and TNF in cord blood, amniotic fluid and the blood of the newborn were performed, using enzyme linked immunosorbent assay(ELISA,R&D Co.). Cytokines of the supernatant of incubated cellular pellet were also measured. Cord blood IL₁β level was significantly higher in induced vaginal delivery than that of the normal vaginal, emergency, and elective cesarian section delivery(p<0.001). Plasma IL₁β level of the newborn with infection or stress was elevated and the level was higher in infection than that of the newborn with stress during delivery. Premature baby had higher level than normal newborn. Cord blood IL₁βlevel was lower than that of amniotic fluid in elective cesarian section delivery. In normal vaginal delivery, IL₁βlevel of the cellular supernatant was higher than that of the plasma and showed good correlation(r=0.92, p<0.05). In newborn with infection, plasma IL₁βlevel was high in the cases with low supernatant level and the plasma level was low in the cases with high supernatant IL₁β. IL6 was detcted from the plasma and cellular supernatant of the newborn with infection and the amniotic fluid. TNF was detected in cellular supernatant of 3 among 8 newborn with infection.

영양교육이 편식 아동의 식행동에 미치는 효과 : 인천지역 초등학생을 중심으로 An Investgation of Children at Elementary Schools in Incheon

진정희,이강자,이윤희 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.1

This study investigated the effects of a 7 week nutritional educational program on the unbalanced dietary habits, tastes, dietary attitudes, and nutritional knowledge of 127 fourth grade students. The subjects were selected from seven elementary schools that were under the supervision of the Dongbu Office of Education in Incheon. Results showed that most of the subjects were fully aware of the fact that they were on an unbalanced diet. It was also revealed that the main reason for their unbalanced diet was that they tended not to eat foods that did not fit their tastes. After implementation of the 7 week nutritional education, the subjects' unbalanced dietary habits significantly decreased, but their desires to fix their unbalanced diet failed to increase. The subjects' tastes showed a positive change in their perception towards vegetables, seafood, and seaweed to a significant degree; however, their appetite for meat, eggs, beans, frozen foods, and processed goods did not show any noticeable change. A significant increase was also found on the level of the subjects' nutritional knowledge but not in their dietary habits and dietary attitudes.

정상 성인에 경구 투여한 Cefixime 두 정제의 생물학적 동등성 비교

강진양,서성훈,이경태,문창훈,강진한,이동건,최정현,신완식 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.4

목적 : 식품의약안전청 고시 제 1998-86호(1998. 8.26) "생물학적 동등성 시험 기준"에 의하여 섹심 캅셀(시험약, 한국유나이트제약)과 슈프락스 캅셀(대조약, 동아제약)의 생물학적 동등성을 비교 검토하였다. 방법 : 2×2 라틴 방격법에 따라 건강한 성인 남성 지원자 20명에게 cefixime 100㎎씩 경구투여하였다. 약제투여 후 12시간까지 일정간격으로 채혈하였고 각 피험자들의 혈중약물농도 데이터로부터 구한 Area under the concentration (AUC), C_(max), T_(max) 등의 생체이용률 파라미터에 대해 통계학적으로 고찰하여 두 제제간의 생물학적 동등성을 평가하였다. 결과 : AUC, C_(max), T_(max)에 대한 평균값의 차가 각각 1.26%, 3.73%, 6.21%로서 모두 대조약의 20% 이내에 들어 생물학적 동등성 판정기준의 전제조건을 만족하였다. 분산분석 결과 AUC, C_(max), T_(max)의 각 비교 항목에 있어서 모두 유의수준 α=0.05의 군/순서효과 검정에서 F비가 F 분석표의 한계값보다 작아 교차시험이 제대로 이루어졌음을 확인할 수 있었으며, AUC, C_(max), T_(max) 각 비교항목에 있어서 유의수준 α=0.05에서 대조약에 대한 최소검출차(Δ)가 각각 17.74%, 17.05%, 15.67%로 모두 20% 이내이었으며, 검출력(1-β)도 모두 0.8 이상으로 나타나 생물학적 동등성 판정기준을 만족시켰다. 또 AUC, C_(max), T_(max) 각 비교항목에 있어서 대조약에 대한 생체이용률 차이의 신뢰한계(δ)가 ±20% 이내이어야 한다는 생물학적 동등성 판정기준을 모두 만족시켰다. 결론 : 이상의 실험결과로 시험약은 대조약에 대하여 생물학적 동등성 평가항목인 AUC, C_(max), T_(max)에서 모두 판정기준을 만족시켜 시험약은 대조약과 생물학적으로 동등하다고 사료된다. Background : The study was designed to compare the bioeqivalence between the test (CEXIME®. United Korea. Co., Ltd) and control (SUPRAX®. Dong-a Pharm. Co.. Ltd) capsules of cefixime. Methods : Twenty. healthy, male volunteers completed the study Each subject ingested single dose (100 ㎍) of the control and test drugs in 2?2 crossover design with a week drug-free interval between the doses. Blood samples were collected serially up to 12 hours and plasma concentrations of cefixime were measured by high-performance liquid chromatography with UV detection. A non-compartmental approach was used for analysis of the concentration-time data. Results : The area under the curve (AUC), the maximum concentration of drug (C_(max)). and time to reach C_(max)(T_(max)) did not show any significant difference between the two preparations by ANOVA. The mean differences of AUC, C_(max), and T_(max) were within 20% of the control drug, those were 1.26%. 3.73%. and 6.21%. respectively. The confidence limits of three parameters were satisfied the bioeqivalence criteria. Conclusion : These results suggest that the test drug was bioequivalent with the control drug.

비전기식뇌관의 트렁크라인 시차가 발파진동에 미치는 영향

강추원,고진석,김재웅 朝鮮大學校 建設技術硏究所 2000 建設技術硏究 Vol.20 No.1

In this study, blasting condition uniformed, and vibration value changed by the trunk line and measuring distance was measured. Four patterns of delay time of surface detonator and trunk line which are used at open fit blasting UB-25 and surface detonator of UB-17, trunk line UB-17 and surface detonator of UB-42, and trunk line of UB-25 and surface detonator of UB-42 are used in pattern 1, 2, 3, and 4 respectively, In result, the overlap time in pattern 1, 3 are 10 times respectively. Because of that reason, the value of vibration velocity in pattern 3 is smaller than in pattern 1. As the time difference of Trunk line, a method of decreasing the surface vibration is to design the number of overlap minimized a t interval time.

관해유도 항암요법을 받는 백혈병 환자에서 진균 감염증의 예방 : 무작위 배정법과 이중 눈가림법에 의한 Fluconazole과 Nystain의 효과에 관한 다기관 공동연구 A Randomized, Double-blind, Multicenter Trial to Compare Fluconazole with Nystatin

최강원,오명돈,배현주,백경란,박선양,김병국,신완식,강문원,진종률,박종원,김춘추,김동집,한지숙,민유홍,이선주,고윤웅 대한화학요법학회 1993 대한화학요법학회지 Vol.11 No.2

Fluconazole의 진균 감염증 예방 효과와 안전성에 관하여 3개 대학병원에서 관해유도화학요법을 받는 급성 백혈병환자를 대상으로 무작위 배정법과 너도나도 누가림법에 의하여 연구하였다. 모두 62명의 환자에게 fluconazole(100㎎ bid) 또는 nystatin(1,000,000IU/day)을 무작위로 투여하였다. 투약은 관해유도화학요법과 같은 날짜에 시작하여 호중구수가 1,000㎣이상으로 회복되거나 진균 감염증이 확인되거나 의심되어 Amphotericin-B를 시작하거나, 약과 관련된 부작용이 나타날 때까지 계속하였다. 진균 colonization은 fluconazole군에서 감소하였으나 nystqatin군에서는 증가하였다, 표재성 진균감염증으로 nystatin군에서 C. albicans 진균혈증 1례와 C.parasilosis 진균혈중 1례가 발생하였다. 경험적 항진균요법으로 Amphotericin-B를 투여한 경우는 fluconazolerns 34명중 7례(21%), nystatinrns 28명중 10례(36%)였다(p<0.05). Fluconazole군과 nystatin군 사이에 부작용이나 사망률에 차이는 없었다. 결론적으로, fluconazole은 관해유도화학요법을 받는 급성 백혈병환자에서 진균의 colonization을 줄이는데 효과적이고 안전한 항진균제이다. We made a randomized, double-blind, multicenter trial to compare the efficacy and safety of fluconazole with nystatin for prevention of fungal infections in patients with acute leukemia. Sixty-two adult undergoing remission induction chemotherapy for cute leukemia were enrolled. Patients were randomly assigned to receive either fluconazole (100㎎ bid) or nystatin(1,000,000IU×6/day) with corresponding placebo. The study drug was started in initiation of chemotherapy and continued until recovery of neutrophil counts(>1,000/㎣), development of proven or suspected invasive fungal infection, or the occurrence of drug-related toxicity. Fungal colonization decreased in fluconazole(F) group, however increased in nystain(n) group. Superficial fungal infection occurred in 1 of 34 F group, whereas invasive fungal infection developed in 3 of 28 N group. Empirical amphotericin-B therapy was given in 7 of 34(21%) F group and 10 of 28(36%) N group(p>0.05). The incidence of drug-related side effects and overall moratlity were similar in both study groups.

米穀貯藏害蟲 밤빛쌀도둑(Tribolium castaneum)의 加害習性 및 生態的 特性에 관한 硏究

金奎眞,朴江龍 전남대학교 농업과학기술연구소 2000 農業科學技術硏究 Vol.35 No.-

This study was carried out to investigate damage aspects and ecological characteristics of red flour beetle which caused serious damages in stored grain pests in South area. The results were obtained as follows; Morphological characteristics of red flour beetle were 0.6±0.1, 5.6±0.5, and 3.8±0.2mm length with eggs, larvae and pupae, respectively. Also female and male of adults were 4.0±0.1 and 3.8±0.1mm, respectively, Each rearing periods was 6.0±1, 34±7.0, 9.0±3.0, 45±10, 65±15 days with egg, larva, pupa and adult female, male, respectivery. Also over-wintering adult was 210±15, 332±15 days with female and male, respectively. The host plants of red flour beetle were surveyed of 10 cereals, 1 bean, 3 farina, 7 processed goods, 2 herbs. Especially, the degree of feeding preference showed high in brown rice, barley and corn flour. Red flour beetle has three generation per a year. Its peak time appeared in mid-May to early-June, mid-July to late and early-September to late. Maximum peak time was the third generation. Damage degrees of red flour beetle showed on brown rice > polished rice > rough rice in rice and barley > pressed barley ≥ polished barley > naked barley in barley. Damage parts of brown rice showed by embryo parts > awn parts > back and front parts.

수직 밀도 구배를 가진 지질 구조에서의 중력 자료 역산과 목적함수 특성

고진석,서동우,강추원 조선대학교 동력자원연구소 1995 動力資源硏究所誌 Vol.17 No.2

This thesis presents some results numerical experiments on the 2-D inversion of gravity data obtained in the structure models. The structure models are represented by their cross-sections of N-sided polygons with density contrasts which are varying with depths. Gravity data for the structure models are calculated by theoretical formulas and are regarded as the true observed gravity data. The inversion of the true data each model is performed by the damped least squares inversion method. Results of this study show that the subsurface interface and the surface density contrast of each model are accurately determined when the vertical density gradient is known. In cast where the density gradient is unknown, the inversion gives incorrect results. But the shape and the density gradient of the model are determined correctly when the surface density contrast is known as is the usual case. Correct inversion can be generally guaranteed by the following conditions; The initial assumption of unknown parameters such as the number of a polygon's vertices should be made reasonably. A way to estimate a reasonable initial model is to compare the objective function values obtained from various unknown parameters and to select the parameters corresponding to the minimum value.

용접부의 표면피로균열 수명 평가에 관한 연구

朴庚銀,鄭鎭成,李龍福 弘益大學校 科學技術硏究所 1995 科學技術硏究論文集 Vol.6 No.-

In this study, to evaluate the fatigue life of surface crack in welding material general structural rolled steel(SS400) was used and welding was performed by MIG butt process. After that, it was machined the same pattern`s initial surface flaw on each welding zone divided by welding metal zone(WM), heat affected zone(HAZ), base metal zone(BM) and boundaries. Using this specimen it could be well evaluated the fatigue life in welding zone. The result are summarized as follows: 1. In each welding zone surface fatigue crack varies from initial aspect ratio of two to semicircle shape at first, after that the aspect ratio of it is reduced gradually. Aspect ratio indicates largely in order of the boundary of HAZ and BM, BM and HAZ, the boundary of WM and HAZ and WM. 2. Surface fatigue crack growth rate is larger in surface direction compare with depth direction at first and it shows that approaches in two direction during fatigue crack propagate continuously. Fatigue crack growth rate indicates largely in order of the boundary of HAZ and BM, BM and HAZ, the boundary of WM and HAZ, and WM. 3. Fatigue life indicates largely in order of WM, the boundary of WM and HAZ, HAZ, BM and the boundary of HAZ and BM. 4. The ratio of initial life to fatigue life indicates largely in order of HAZ, the boundary of HAZ and BM, BM, the boundary of WM and HAZ, and WM. It belongs to 34% to 58% in welding zone.