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Chih Ming Chiang,Wen Shuo Kuo,Kuan-Hung Lin 한국원예학회 2014 Horticulture, Environment, and Biotechnology Vol.55 No.2
Previously, we reported that increased ascorbate peroxidase (APX) and superoxide dismutase (SOD) activitiesprovide sponge gourd (SG) and winter squash (WS) plants with increased waterlogging and chilling stress tolerance,respectively. The objectives of this work were to clone the APX gene from SG and the SOD gene from WS, andmeasure the regulation of APX and SOD gene expressions under flooding and chilling stress, respectively. The fulllengths of APX and SOD cDNA were found to be 761 and 703 bp, respectively. Different tissues from bitter melon(BM) and SG displayed wide variations in their expression profiles, and the highest level of APX transcripts weredetected in roots of SG at 72 hours of flooding treatment. Additionally, the differential SOD expressions of BM andWS were directly associated with chilling stress responses. A phylogenetic analysis of APX and SOD indicated thatplant APXs and SODs diverged into two major clusters.
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An Jen Chiang,Min-Yu Chen,Chia-Sui Weng,Hao Lin,Chien-Hsing Lu,Peng-Hui Wang,Yu-Fang Huang,Ying-Cheng Chiang,Mu-Hsien Yu,Chih-Long Chang 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.5
Objective: The malignant transformation (MT) of ovarian mature cystic teratoma (MCT)to squamous cell carcinoma (SCC) is very rare. This study analyzed cases from multiplemedical centers in Taiwan to investigate the clinicopathologic characteristics, treatment, andprognostic factors of this disease and reviewed related literature. Methods: Pathological reports of 16,001 patients with primary ovarian cancer who weretreated at Taiwan medical centers from 1990 to 2011 were reviewed. In total, 52 patients withMT of MCT to SCC were identified. Results: Among all ovarian MCTs, the incidence of MT to SCC is 0.2%. The median age ofpatients was 52 years (range, 29–89 years), and the mean tumor size was 10.5 cm (range, 1–40cm). We analyzed the patients in our study and those in the literature and determined thatearly identification and complete surgical resection of the tumor are essential for long-termsurvival. In addition, adjuvant chemotherapy or concurrent chemoradiotherapy can be usedto treat this malignancy. Old age, large tumor size (≥15.0 cm), and solid components in MCTsare suitable indicators predicting the risk of MT of MCT to SCC. Conclusion: Similar to general epithelial ovarian cancers, the early detection of MT of MCTto SCC is critical to long-term survival. Therefore, older patients with a large tumor or those with a tumor containing a solid component in a clinically diagnosed MCT should beevaluated to exclude potential MT to SCC.
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Smart monitoring system with multi-criteria decision using a feature based computer vision technique
Chih-Wei Lin,Wen-Ko Hsu,Dung-Jiang Chiou,Cheng-Wu Chen,Wei-Ling Chiang 국제구조공학회 2015 Smart Structures and Systems, An International Jou Vol.15 No.6
When natural disasters occur, including earthquakes, tsunamis, and debris flows, they are often accompanied by various types of damages such as the collapse of buildings, broken bridges and roads, and the destruction of natural scenery. Natural disaster detection and warning is an important issue which could help to reduce the incidence of serious damage to life and property as well as provide information for search and rescue afterwards. In this study, we propose a novel computer vision technique for debris flow detection which is feature-based that can be used to construct a debris flow event warning system. The landscape is composed of various elements, including trees, rocks, and buildings which are characterized by their features, shapes, positions, and colors. Unlike the traditional methods, our analysis relies on changes in the natural scenery which influence changes to the features. The “background module” and “monitoring module” procedures are designed and used to detect debris flows and construct an event warning system. The multi-criteria decision-making method used to construct an event warring system includes gradient information and the percentage of variation of the features. To prove the feasibility of the proposed method for detecting debris flows, some real cases of debris flows are analyzed. The natural environment is simulated and an event warning system is constructed to warn of debris flows. Debris flows are successfully detected using these two procedures, by analyzing the variation in the detected features and the matched feature. The feasibility of the event warning system is proven using the simulation method. Therefore, the feature based method is found to be useful for detecting debris flows and the event warning system is triggered when debris flows occur.
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Chih-Yang Liu,Han-Lin Chiang,Ser-Chen Fu,Yu-Chin Su,Cheng-Lun Hsiao,Fu-Yi Yang,Shinn-Kuang Lin 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.1
Background and Purpose Te requirement for neurology liaison is increasing in accordance with the growing health care demands associated with aging populations. Te aim of this study was to characterize the nature of neurological inpatient liaisons (NILs) to help plan for the appropriate use of neurology resources. Methods Tis was a retrospective cross-sectional study of NILs in a secondary referral hospital over a 12-month period. Results Tere were 853 neurological consultations with a liaison rate of 3% per admission case. Chest medicine, gastroenterology, and infectious disease were the three most frequent specialties requesting liaison, and altered consciousness, seizure, and stroke were the three most frequent disorders for which a NIL was requested. Infection was the most common cause of altered consciousness. Epilepsy, infection, and previous stroke were common causes of seizure disorders. Acute stroke accounted for 44% of all stroke disorders. Electroencephalography was the most recommended study, and was also the most frequently performed. Ninety-fve percent of emergency consultations were completed within 2 hours, and 85% of regular consultations were completed within 24 hours. Te consult-to-visit times for emergency and regular consultations were 44±47 minutes (mean±standard deviation) and 730±768 minutes, respectively, and were shorter for regular consultations at intensive care units (p=0.0151) and for seizure and stroke disorders (p=0.0032). Conclusions Altered consciousness, seizure, and stroke were the most common reasons for NILs. Half of the patients had acute neurological diseases warranting immediate diagnosis and treatment by the consulting neurologists. Balancing increasing neurologist workloads and appropriate health-care resources remains a challenge.
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Chih-Chien Wang,Cheng-Yu Chiang 한국데이터전략학회 2019 Journal of information technology applications & m Vol.26 No.6
On the Internet age, the news is generated and distributed not only by traditional news media, but also by a variety of online news media, news platforms, content websites/content farms, and social media. Since it is an easy task to create and distribute news, some of these news reports may contain fake or false facts. In the end, the cyberspace is full of fake or false messages. People may wonder if these fake news actually influence our decision making. In this paper, we discussed a real case of fake news. In this case, a Taiwanese company used some fake news, advertorial news, and news placement to manipulate or influence its stock price and trade volume. We collected all news for the case company during a period of four years and five months (from January 2013 to May 2017). We analyzed the relationship between published news and stock price. Based on the analysis results, we conclude that we should not ignore the influence of news placement and fake business news on the stock price.
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Wang, Chih-Chien,Chiang, Cheng-Yu Korea Data Strategy Society 2019 Journal of information technology applications & m Vol.26 No.6
On the Internet age, the news is generated and distributed not only by traditional news media, but also by a variety of online news media, news platforms, content websites/content farms, and social media. Since it is an easy task to create and distribute news, some of these news reports may contain fake or false facts. In the end, the cyberspace is full of fake or false messages. People may wonder if these fake news actually influence our decision making. In this paper, we discussed a real case of fake news. In this case, a Taiwanese company used some fake news, advertorial news, and news placement to manipulate or influence its stock price and trade volume. We collected all news for the case company during a period of four years and five months (from January 2013 to May 2017). We analyzed the relationship between published news and stock price. Based on the analysis results, we conclude that we should not ignore the influence of news placement and fake business news on the stock price.
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Shu-Chiang Lin,Satria Fadil Persada,Reny Nadlifatin,Hsiang-Yu Tsai,Chih-Hsing Chu 한국정밀공학회 2015 International Journal of Precision Engineering and Vol.2 No.4
The Green Mark eco-label constitutes an essential program introduced by Taiwan’s Environmental Protection Administration to support environmental protection. In the manufacturing industry, the Green Mark eco-label is intended to enable differentiating between manufacturers that apply green processes and those that do not. This paper presents an assessment model for identifying manufacturers’ initial intention to apply the Green Mark eco-label. The model was derived from the certification process flow. A total of 200 structured questionnaires were distributed to manufacturers in Taiwan, and 172 responses were retrieved. The model was analyzed by applying structural equation modeling, and the correlation of review process and end certification process exhibited the strongest correlation. Improving the document verification stage is highly likely to increase the overall initial intention ofmanufacturers to participate in the Green Mark eco-label program. The overall certification process contributed 16% to the total initial intention of manufacturers to apply the Green Mark eco-label to their products.
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Mei-Fang Chen,Chih-Hao Chiang 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.10
Marketers commence to use types of brand alliance strategies including co-branding. Many previous studies focused on the strategic performance of the co-branded credit card or loyalty programs. The introduction of the department store co-branded credit card successfully increases revenues and expands the market shares for both the banking industry and the department store industry in Taiwan. In view of the importance of co-branding strategy to extend market share for both the banking industry and the retailing industry in Taiwan, it is worthy to have a better understanding of whether or not consumer’s affective loyalty to the bank and/or consumer’s affective loyalty to the department store will influence his/her attitude toward the department store co-branded credit card, which in turn influence his/her intention to continue to use or apply for the co-branding credit card. This study aims to ascertain what factors determine consumer’s intention to continue to use and/or to apply for the department store co-branded credit card. This study collected data on the Internet Website from December 8, 2013 to January 30, 2014. A total of 444 valid data were used in this study. The two-stage procedure of structural equation model (SEM) analysis was conducted to examine the hypothetical causal relationship in the proposed theoretical model. The results indicate that for those who had applied for the department store co-branded credit card, consumer’s affective loyalty to the bank and consumer’s affective loyalty to the department store indeed exert positive impacts on his/her attitude toward department store co-branded credit card, which in turn influence his/her intention to continue to use the co-branded credit card. In addition, for those who did not have the department store co-branded credit card, consumer’s affective loyalty to the department store can induce his/her attitude toward department store co-branded credit card, which in turn influences his/her intention to apply for co-branding credit card. The implications and suggestions for both the banking industry and the retailing industry are also provided in this study.
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Shu-Hua Yang,Kai-Chiang Yang,Chih-Wei Chen,Ting-Chun Huang,Yuanhui Sun,Ming-Hsiao Hu 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.5
Study Design: In vitro cell culture study. Purpose: This study aims to investigate the impact of transforming growth factor-beta1 (TGF-β1) and lovastatin on differentiating human mesenchymal stem cells (MSCs) toward nucleus pulposus (NP)-like phenotype. Overview of Literature: MSCs offer a cell source to the cell-based therapy for intervertebral disc degeneration. TGF-β1 is used to induce MSCs to differentiate into NP-like cells; however, an undesired expression of collagen type I has been reported. Statins reportedly stimulate expression of bone morphogenetic protein-2 (BMP-2) and promote the chondrogenic phenotype to NP cells. However, the effects of statins with or without TGF-β1 on the differentiation of MSCs into NP-like cells remain unclear. Methods: Human MSCs were treated with TGF-β1 alone, lovastatin alone, and simultaneous or sequential treatment with TGF-β1 and lovastatin. After the proposed stimulation, the total RNA was extracted to assess the expression profile of NP cells-specific genes. Hematoxylin–eosin staining was used for examining the microscopic morphology. Furthermore, we detected the syntheses of S-100 protein, aggrecan , and collagen type II in the extracellular matrix using immunohistochemical staining. Results: Simultaneous or sequential treatment of TGF-β1 and lovastatin could further augment the BMP-2 overexpression compared with lovastatin-alone treatment. However, the mRNA expression of aggrecan and collagen type II was not compatible with the expression level of BMP-2 . Immunohistochemical studies revealed compatible production of aggrecan, collagen type II , and S-100 protein in all three groups treated with lovastatin. Cells in groups treated with lovastatin were less populated than that in the group treated with TGF-β1 alone. Conclusions: This study demonstrates a promising role of lovastatin in inducing human MSCs into NP-like cells. However, further optimization of cell density before lovastatin treatment, treatment duration, and combination with TGF-β1 are warranted to attain better stimulatory effects.
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