뇌졸중 환자에서 연하장애와 신체기능장애의 연관성

김도성,심영주,김기찬,정호중 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Backgrounds : In almost stroke patients, dysphagia is improved with rehabilitation therapy. But, it is not identified the relationship between dysphagia and physical function recovery in stroke patients. Methods : A total of 21 patients with stroke-caused swallowing disorders based on a videofluoroscopic swallowing study (VFSS) were examined swallowing function and physical function at admission and after treatment for 4 weeks (including Vitalstim). Swallowing function was evaluated by the functional dysphagia scale (FDS) using VFSS before treatment and after treatment. Physical function was evaluated by the motricity index (MI) and modified barthel index (MBI) at admission and after 4 weeks. And the relationship between dysphagia and physical function recovery was evaluated. Results : After treatment for 4 weeks, total score, residue in oral cavity, oral transit time, laryngeal elevation and epiglottic closure, residue in valleculae, residue in piriform sinus, coating of pharyngeal wall after swallow were significantly decreased in FDS (p<0.05). There were a significant improvement in MBI (p<0.05) and the correlation between FDS and MBI. But, MI was not showed correlation with FDS. Conclusions : There was relationships between swallowing function improvement and recovery of physical function in almost FDS factors.

동사 범주로서의 距離-개념 : 時制에 대한 하나의 텍스트 언어학적 접근 Eine textlinguistische Untersuchung zur Tempusbeschreibung

김진도 독일언어문학연구회 1995 독일언어문학 Vol.4 No.-

10MgO-10Fe_2O_3-30Na_2O-5OSiO_2 유리의 Mo¨ssbauer 효과 연구

홍치유,박관호,백승도,문찬호,조수열 동국대학교 1987 論文集 Vol.26 No.-

The Mo¨ssbauer effect studies of the quenched glass and heat-treated glasses were performed. The Debye and Einstien temperatures of the quenched glass, determined using the center shift and kinetic temperature, are 540K and 430K respectively. The X-ray diffraction pattern showed that the heat-treated glasses were crystallized. Form the isomer shift of the heat-treated glasses, it was concluded that the Fe^(3+) ion is predominantly octahedrally coordinated.

원발성 중추신경계 임파종 : 치료 및 생존율 Treatment and Survival Rate

남도현,이상형,김동규,정희원,지제근,왕규창,김현집,최길수,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.3

The authors report on 17 patients having primary central nervous system(CNS) lymphomas between January, 1981 and August, 1992. All patients were treated at Seoul National University Hospital. Only three cases underwent surgery only and fourteen cases underwent surgery and radiation therapy with or without chemotherapy. There were no immunosuppressive patients. Sixteen patients were analyzed for survival studies, because one case was lost during follow-up. The median survival time(MST) was 26 months and one- and two-year survival rates for the 16 patients were 87.5% and 65.6% respectively. The rate of survival was analyzed according to possible prognostic factors ; age and sex, multiplicity and location of tumors, preoperative Karnofsky performance score(KPS), pathological subclassification, type of surgery, preoperative steroid therapy, postoperative adjuvant therapy, extent of radiation, chemotherapy and the degree of response to treatment at three months follow-up. Postoperative adjuvant therapy and the degree of response to the treatment correlated with survival. Fourteen patients who underwent postoperative adjuvant therapy had a median survival time of 63 months. The one- and two-year survival rates were 100% and 75% respectively compared to the MST of 1.5 months with survival rates of 0% and 0% retrospectively for the two patients who did not. A higher long term survival rate was observed in the group with better immediate responses. In nine of 16 patients with complete responses, the MST, one-, and two-year survival rates were 63 months, 100%, and 83% respectively. The authors suggest that preoperative application of steroids may be considered in case of clinically suspected primary CNS lymphomas. It is concluded that after obtaining the tissue diagnosis of primary CNS lymphomas, radiotherapy with or without chemotherapy should be performed until the complete response.

만성 호중구성 백혈병 1례

기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.

NiCdFe₂O₄의 구조와 자기적 성질

홍치유,조수열,백승도 동국대학교 자연과학연구소 1991 자연과학연구 논문집 Vol.11 No.-

X-ray 회절선을 조사한 결과 Ni?Cd?Fe?O?의 조성을 갖는 ltfy는 x값의 증가에 따라 inverse spinel 구조에서 normal spinel 구조로 변하며, 격자상수는 선형적으로 증가하였다. 또한 Mossbauer spectrum을 상온(300K)에서 측정하여 분석한 결과, 시료의 wrl적 성질은 x값의 증가에 따라 준강자성에서 상자성으로 변화되었으며, 시료는 Yafet-Kittel의 자기구조를 이루는 것을 알 수 있었다. According to the X-ray diffractometry, the structure of Ni?Cd?Fe?O? changes from inverse spinel to normal spinel and lattice constant varies linearly, as increasing x. From the result of the Mossbauer spectroscopic study, it is found, that the magnetic properties of Ni?Cd?Fe?O? change from ferrimagnetism to paramagnetism as increasing x, and the Ni?Cd?Fe?O? have the Yafet-Kittel magnetic structure.

새로운 抗菌劑로서 1-(phenoxymethyl)benzotriazole 誘導體의 合成과 定量的 構造活性關係(QSAR) 分析

成洛道,林治煥,崔宇永,高東成,權奇星 충남대학교부설 생명공학연구소 1992 생물공학연구지 Vol.2 No.-

14종의 새로 합성된 1-(phenoxymethyl)benzotriazole(Ⅰ)(Y=0)과 1-(thiophenoxymethyl)benzotriazole (Ⅱ)(Y=S) 및 1-(azidomethy) benzotriazole(Ⅲ) 유도체의 구조와 in vitro에서 Pyricularia oryzae, Fusarium oxysporum f. sp. sesami, Valsa ceratosperma 및 Botrytis cinerea에 대한 균사 생장을 50% 저해하는 활성(pI_50)사이의 구조-항균활성 상관관계들을 QSAR방법으로 연구하였다. (Ⅰ)의 항균활성은 (Ⅱ)와 (Ⅲ)보다 우세하였으며 phenoxy group(Ⅰ)의 치환기 효과는 수소 결합성 (HB)과 포물선 관계의 electronic effect(σ), steric effect(B_1) 그리고 hydrophobic effect(π)로 설명된다. P. oryzae와 F. axysporum f. sp. sesami의 항균 활성에 대한 치환기의 적정값은 B_1=1.40A, (H)와 σ=0.07∼0.15, (H)이고 V. ceratosperma와 B. cinerea에 대하여는 각각 σ=0.23∼0.28, (C1)과 π=0.70, (C1)이었으며 가장 효과적인 화합물인 (Ia)와 (Id)의 구조-활성관계가 검토되었다 (1990년 5월 11일 접수, 1990년 9월 20일 수리). The structure-antifungal activity correlations between the structure of fourteen new 1-(phenoxymethyl)benzotriazoles (Ⅰ) (Y=0), 1-(thiophenoxymethyl)benzotriazoles (Ⅱ) (Y=S) and 1-(azidomethy)benzotriazole (Ⅲ) derivatives were synthesized, and their activity, fifty percent inhibition of mycelial growth(pI_50), in vitro against Pyricularia oryzae, Fusarium oxysporum f. sp sesami, Valsa ceratosperma and Botrytis cinerea were investigated using a generalized QSAR method. The activity of (Ⅰ) was superior to those of (Ⅱ) and (Ⅲ). The effect of the substituents (Ⅹ) on the phenoxy group (Ⅰ) was rationalized by a parabolic function of electronic (σ), steric (B_1) and hydrophobic parameter(π), and hydrogen bonding (HB). Where the optimal values of substituent on the fungicidal activity againt P. oryzae and F. axysporum f. sp. sesami are B_1=1.40A ; (H) and σ=0.07∼0.15;(H), and those of substituent on the fungicidal activity against V. ceratosperma and B. cinerea are σ=0.23∼0.28; (Cl), π=0.70; (C1), respectively. The most effective compound (Ⅰa) and (Ⅰd) were examined in this study.

Cd 페라이트의 열적성질에 대한 Mossbauer 효과 연구

홍치유,백승도,이철세 동국대학교 자연과학연구소 1992 자연과학연구 논문집 Vol.12 No.-

이 논문에서는 100-900K의 온도영역에서 CdFe?O?의 Mossbauer 효과를 조사하였다. CdFe?O?의 이성질체 이동치는 온도의 증가에 따라 감소하며, 온도계수는 -5.789×10?㎜/sec·K이다. 사중극자 분열치는 온도에 따른 뚜렷한 변화가 없으며, 흡수선폭은 온도증가에 따라 증가하고, 공명흡수 면적의 온도 의존성을 이용하여 구한 CdFe?O?의 Debye dhsehss 515L이다. Mossbauer effect study is made on CdFe?O? in the temperature range from 100K up to 900K. The isomer shift of the CdFe?O? decrease with the temperature coefficient -5.789×10?㎜/sec·K as the increasing temperature, but we have observed no variation of quadrupole splitting with temperature. The average line width increase slowly with increasing temperature. The Debye temperature of the CdFe?O? calculated by the temperature dependence of the absorption area is 515K.

저온에서의 Iron Powder의 Mo¨ssbauer 효과

洪致裕,白承道,金振璜 동국대학교 1985 論文集 Vol.24 No.-

The Mo¨ssbauer parameters of iron powder were measured from 50K to 303K. As the temperature decreased, the center shift and internal magnetic field increased. And using the kinetic temperature and center shift, we determined the einstein temperature and Debye temperature, to be 316K, 436K respectively. From this result, we think that this method for measuring the Debye temperature is useful.

FMEA를 이용한 기계류 시스템의 신뢰도 분석

진도훈,우태수,이치우 한국공작기계학회 2002 한국공작기계학회 추계학술대회논문집 Vol.2002 No.-

This paper dealt with FMEA, which is a method of the analysis to secure safety and confidence coming up to customers' expectation in consideration of the environment of the corporation, the industrial environment, and the functional improvement. And by using FMEA, We showed the example analyzed the confidence of the Air Supply System. It was proved by the result of the analysis that the rate of the breakdown which is usually regarded as the first important point to reform can't satisfy the selecting basis to improve. Also the result said that it is not right to depend on only the rate of the failure in making the list of the reform. Through the analysis of the breakdown, FMEA can present the important factors of the reform to improve the confidence of the system. In this study would show the important factors of the improvement in order to product the goods guaranteed confidence through the method of FMEA.