Uniaxial Compression Properties and Compression Fatigue Performance of Selective Laser Melted Ti–6Al–4V Cellular Structure

Ming‑Wei Wu,Jhewn‑Kuang Chen,Mo‑Kai Tsai,Pei Wang,Tien‑Lin Cheng,Bo‑Huan Lin,Po‑Hsing Chiang,Annadurai Dhinakar 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.1

The selective laser melted (SLM) Ti–6Al–4V cellular solid is a promising material in biomedical and other applications. The mechanical properties of the SLM Ti–6Al–4V cellular material are predominantly controlled by the design of the cellular structure. The objective of this study was to investigate the uniaxial compressive properties and compressive fatigueperformance of the SLM Ti–6Al–4V cellular solid with a new cuboctahedron unit cell reinforced by four diagonal strutsand two horizontal struts along the X and Y axes. The infuences of hot isostatic pressing (HIP) on the various mechanicalproperties were also examined. The results showed a smoother stress–strain curve and fewer stress oscillations in the HIPspecimen than in the SLM specimen. The HIP process slightly decreased the yield strength of the SLM sample from 55 to52 MPa. Under uniaxial compressive stress, the SLM and HIP specimens exhibited layer-by-layer fracture and diagonalshear fracture, respectively. Furthermore, the HIP treatment signifcantly increased the fatigue performance and improved thefatigue endurance ratio at 106cycles from 0.15 to 0.35. The HIP treatment contributed to several positive efects, includingphase transformation from brittle α′ to α + β, the elimination of strut porosity and residual stress, an increase in lath size,and a better combination of strength and ductility, thereby improving the fatigue performance. The efects of stress mode onthe fracture mechanism were also clarifed using in situ observation in combination with digital image correlation.

朱光潛的比較詩學思想及其實踐

鐘名誠 한국중국문화학회 2002 中國學論叢 Vol.14 No.-

Zhu Guangqian is a pioneer of modern Chinese comparative poetics. In the course of the exchange between oriental culture and western culture, he looked into the Chinese modern poetic movement with his international perspective. In his research of Chinese and western poems, he applied the general principles and ideas of comparative poetics, i.e. the applicable value principles; the mutually depicting principles; the principles of the sense of history; the comprehensive comparison principles and etc., to explore the art of the Chinese and western poems Zhu has made great valuable efforts in the comparative research of western and Chinese poems and had made great contributions to the healthy development of Chinese modern poems. Today whenever we encounter any difficulties in our modern Chinese poems, we will refer to Zhu's comparative poetics thoughts. We find Zhu's thoughts still very practical and instructive.

녹음 구어 제시가 중도정신지체 성인여성의 목욕 능력 개선에 미치는 효과

鄭如意,陳明聰,陳政見 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.2

1. This study aimed to explore the effect of recorded auditory prompts on helping an adult with profound mental retardation to take bath independently. 「A-B-C-A-C」design, a kind of single-subject experiment was adopted. Three phases, baseline phase, intervention phase(B): auditory prompt, and intervention phase(C): recorded auditory prompt were included. A female with profound mental retardation participated in the experiment. It took over seven months to finishing the intervention. The results of the experiment indicated that auditory prompts, whether human auditory prompt or recorded prompt, could help the client to take bath more independently. The families of the client also regarded recorded auditory prompt was a feasible solution. Based on the result, there were some suggestions for the further research. 본 연구의 목적은 녹음 구어 제시를 이용해서 극 중도 지능장애 성인 여성 스스로 목욕 동작을 완성 할 수 있도록 도와주는 효과에 대한 연구입니다. 본 연구에 사용하는 연구법은 ⌜A-B-A-C-A-C⌟역 설계이다. 기선기의(A)개입一(B)인공구어제시 개입二(C)녹음 구어 제시로 나누어졌다. 실험기간은 모두 7개월 반이었다. 연구결과는 피 실험자가 스스로 목욕할 때와 비교했을 때 인공구어 제시와 녹음구어 제시는 모두 피 실험자가 목욕 동작을 완성 하는 데에 효과가 있는 것으로 나타났다. 이 외에도 녹음 구어 제시는 피 실험자 가족들도 받아들일 수 있다. 본 연구 결과에 근거해서 연구자들은 미래 응용과 연구에 대한 건의도 제출하였다.

Sofosbuvir/Ledipasvir in the Treatment of Chronic Hepatitis C - A Subgroup Analysis from A Nationwide Real-World HCV Registry Program (TACR) in Taiwan

( Ming-Lung Yu ),( Chi-Yi Chen ),( Kuo-Chih Tseng ),( Ching-Chu Lo ),( Pin-Nan Cheng ),( Cheng-Yuan Peng ),( Ming-Jong Bair ),( Chih-Lang Lin ),( Chi-Ming Tai ),( Chi-Chieh Yang ),( Chih-Wen Lin ),( C 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: TASL HCV Registry (TACR) is a nationwide registry program organized and supervised by Taiwan Association for the Study of the Liver (TASL), which aims to setup the database and biobank of patients with chronic hepatitis C (CHC) in Taiwan. The present study aimed to evaluate the treatment outcome of sofosbuvir (SOF)/ledipasvir (LDV) in Taiwanese CHC patients in TACR. Methods: By May 2020, 19 tertiary hospitals, 23 community hospitals and one primary care clinic join the TACR program. The baseline characteristics, prior liver and non-liver related medical history, DAA regimens, laboratory results, treatment course and outcome were recorded. The primary objective was sustained virological response, defined as undetectable HCV RNA 3 months after end-of-treatment (SVR12). Results: A total of 4742 SOF/LDV+ ribavirin treated CHC patients with available SVR12 data from 39 sites were enrolled in the current analysis. The mean age was 61.3 years, and female accounted for 54.8% of the population. The dominant viral genotypes were GT1b (52.6%) and GT2 (35.6%). 1354 (28.6%) patients had liver cirrhosis, including 156 (3.3%) with liver decompensation, 552 (11.6%) had preexisting hepatocellular carcinoma (HCC) before DAAs treatment and 413 (8.7%) had hepatitis B virus dual infections. The overall SVR12 rate was 98.5%, with 98.5%, 98.2%, 99.7% and 98.6% in treatment- naïve non-cirrhotics, treatment-naïve cirrhotics, treatment- experienced non-cirrhotics and treatment-experienced cirrhotics patients, respectively. While patients were stratified by HCV genotype, the SVR12 was 98.5%, 98.4% and 98.5% among those with GT1, GT2 and GT6 infection, respectively. The strongest factor independent associated with treatment failure was DAA adherence < 60% (odds ratio [OR]/95% confidence intervals [CI]: 125.4/25.7-612.4, P<0.0001), followed by active HCC (OR/CI: 6.20/2.57-14.97, P<0.0001), HIV co-infection (OR/CI: 3.01/1.14-7.92, P=0.026), and male gender (OR/ CI: 1.85/1.09-3.13, P=0.023). The eGFR decreased significantly at the end of treatment (EOT) (89.3 ml/min/1.73㎡ vs. 93.2 ml/min/1.73㎡, P< 0.001) and remained stable 3 months after EOT (89.3 ml/min/1.73㎡). However, the decreased eGFR was observed only in patients whose baseline eGFR > 90 ml/ min/1.73㎡. Instead, patients with chronic kidney diseases whose pretreatment eGFR < 60 ml/min/1.73㎡ had improved eGFR after SOF/LDV. Conclusions: SOF/LDV is highly effective in treating CHC patients in real-world setting of Taiwan. The satisfactory result could be explicitly generalized to patients with different viral genotypes and liver disease severities.

Study on Social Transformation in Contemporary China: From the Perspective of Structural Holes

( Cheng Ming Huang ) 한국비교경제학회 2014 비교경제연구 Vol.21 No.1

Since 1978, China`s reform and opening up have led to the rapid development, the entire society presents a great historic change, which is known as the “China miracle”. The market-oriented path selected by contemporary China not only brings the change of the economic operation mode, but also the re-integration of the traditional interest structure. Compared with the former socialist countries and western countries, Chinese social transformation, both in the real structural restriction condition and the development logic, has obvious uniqueness. The process and characteristics of social transformation in contemporary China are studied in the paper. The social transformation of China is mainly embodied in the following changes: from planned economy to market economy, from agricultural(rural) society to industrial(city) society, from closed society to open society, from ethics society to legal society, from state monopoly to social participation, from nationalization to internationalization, and from single culture to multiculturalism, etc.. The social transformation in China on the basis of economic system transformation is not only the change in the social stratification structure, but also the structural change of city population, social culture and other social ideology. Therefore, the social transformation of China is a comprehensive, holistic social structure transformation on various aspects of society, national ideology, culture, political and psychological revolution. The social transformation of China reflects the following characteristics: (1) the combination of mandatory and inductive power, (2) the comprehensive change of social structure, and (3) the flat management in social structure According to the analysis of the structural holes theory, since structural holes is more advantageous to enhance the competitive advantage of players and the value of the entire network, individuals or organizations in the society must establish “structural holes” as many as possible, which implies extensive connection with individuals or groups who are not directly linked with them. By doing this, the players can obtain information and control advantage, and develop the advantage in the competition. Chinese traditional social relations based on family structure obviously lack the natural advantage of building structural holes, so it is necessary to transform into the social relations based on individual as the center. The structural holes theory indicates that the chance of acquiring new information depends on the weak tie between the player and his local network. Most local information in the network is widely shared, and the new information usually comes from non-repeating contact. The player must communicate with external groups to seek larger development opportunities, but the traditional family structure has hampered the external continuous information exchange, which is difficult to adapt to the development of social transformation, Chinese traditional social relations based on family structure will be resolved gradually. Contemporary social transformation in China provides an opportunity for the change of traditional family structure, and the deconstruction of traditional family structure in turn promotes the transformation of the society, and create conditions of breaking the closed boundaries for the individual and organization in the Chinese social structure. With the deepening of social transformation, great changes have taken place in Chinese traditional family structure and social relations, which is characterized by the performance of family culture, urbanization process and population structure. The formation of structural holes in Chinese social networks is increased by population frequent flow, interpersonal expansion and the conversion from closed lifestyle to open-type lifestyle. This paper shows that the social transformation in China has a great impact on traditional family structure formation, and disintegration and reconstruction of the traditional family structure also change the social relations and ocial interest distribution. In this paper, the structural holes theory is not used to analyze the operation of social capital as usual, but used to study the social transformation as a new attempt. Therefore, the discussion will contribute to understand the problems faced by social transformation, the direction of the institutionalization and its social base in China from a new perspective.

Deformation Characteristics and Countermeasures of shallow and Large-span Tunnel Under-crossing the Existing Highway in Soft Soil: a Case Study

Cheng-yong Cao,Cheng-hua Shi,Ming-feng Lei,Li-min Peng,Ruxue Bai 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.8

Hongmian Road goes under Jihe highway by the way of tunnel in Shenzhen City, Guangdong Province, China. The tunnel hassome special characteristics such as shallow depth, large span, soft soil, busy traffic, and long distance under-crossing the operatinghighway, thus there is great difficulty and risk during its construction. A series of in-situ tests were conducted to reveal deformationcharacteristics during tunneling beneath the existing highway by the double-side-drift method (DSDM). The results show that initialconstruction method and measures can't meet the safety requirement of tunnel construction, and the level of risk is extremely high, sothe construction method need to be timely adjusted. By comprehensive analysis, the double-side-drift optimum method (DSDOM) isput forward, on the basis of which a series of optimum measures also have been put forward, such as reasonable constructionmethods, the suitable length of bench and excavation, soil reinforcement measures on tunnel face, optimizing construction process,closing primary support in time and speeding up the construction of secondary lining. Then the feasibility of this optimizedconstruction method and measures are verified by the numerical simulations. Finally, from feedbacks of monitoring results, theoptimum method and measures have been proved to be reasonable and feasible, and they can guarantee a successful pass beneath theoperating highway.

The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells

( Cheng-yen Chiang ),( Kai-di Hsu ),( Yen-yi Lin ),( Chang-wei Hsieh ),( Jui-ming Liu ),( Tze-ying Lu ),( Kuan-chen Cheng ) 한국균학회 2020 Mycobiology Vol.48 No.3

Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent prostate cancer cell line. Results demonstrated that both hexane (GF-EH) and butanol (GF-EB) fraction of G. formosanum ethanol extract inhibited DU145 cell viability in a dose-dependent manner. GF-EH induced cell-cycle arrest in G1 phase of DU145 cells via downregulation of cyclin E2 protein expression. In addition, GF-EB triggered extrinsic apoptosis of DU145 cells by activating caspase 3 gene expression resulting in programed cell death. Above all, both GF-EH and GF-EB show lower toxicity to normal human fibroblast cell line compared to DU145 cell, implying that they possess specific drug action on cancer cells. This study provides a molecular basis of G. formosanum extract as a potential ingredient for treatment of androgen-independent prostate cancer.

Earnings Manipulation, Corporate Governance and Executive Stock Option Grants: Evidence from Taiwan

Ming-Cheng Wu,Yi-Ting Huang,Yi-Jing Chen 한국증권학회 2012 Asia-Pacific Journal of Financial Studies Vol.41 No.3

Executive stock options (ESOs), serving as a compensation mechanism, are widely used in business administration. ESOs link managerial wealth to firm performance and shareholder wealth. The intrinsic value of ESOs is determined by the difference between the stock price and the strike price. Executives, as a result of self-interested incentives, would therefore manipulate firms’ reported earnings for influencing stock prices. Such conduct may boost the value of ESOs and then benefit managers greatly. This study attempts to explore if earnings had been manipulated before the ESO award date to satisfy some self-interested managers. In addition, the paper attempts to reveal the cause and effect relationship between executive incentives and earnings management when compensations are linked to stock prices. The empirical results show that there is a significant downward earnings management phenomenon before the ESO award date. Furthermore, quarterly earnings management occurs frequently around the ESO grant date.

Mechanical Property Test and Analytical Method for Reactive Powder Concrete Columns under Eccentric Compression

Cheng-hua Shi,Min Long,Cheng-yong Cao,Guangcheng Long,Ming-feng Lei 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.4

Reactive Powder Concrete (RPC) has ultra-high strength, toughness and durability. Review studies were focused on the mechanical properties of RPC material and RPC beam. In this paper, the bearing features of RPC columns under eccentric compression with different section dimensions, reinforcement ratios, and conditions of with and without steel fibres were determined through large eccentric compression test of 22 RPC columns. The distribution patterns of stresses over the section of the RPC columns under large eccentric compression were determined under cracking loads. A simple analytical method for the cracking loads was also established. Test results revealed that the thickness ratio of elastic tensile region and the whole tensile region can be 0.4 (with steel fibres) or 0.5 (without steel fibres) when calculating the cracking loads. The tensile stress on the RPC columns showed an isosceles triangle distribution in the tensile region. A simple analytical method for calculating the ultimate loads of RPC columns under large eccentric compression was set up. Test results revealed that the equivalence coefficient of the RPC column in tensile regions can be 0.6 (with steel fibres) or 0.4 (without steel fibres). The method deduced in this paper can be used to design the RPC column under large eccentric compression.

Current Status, Future Trend and General Policies of Forestry in China

Cheng, Ming,Ahmed, Sheikh Ali,Chun, Su-Kyoung,Kim, Jong-In Korea Furniture Society 2006 한국가구학회지 Vol.17 No.3

Based on data collected by the State Forestry Administration (SFA) and other databases, this paper describes the current status, future trend and general policies in China's forestry. Forestry sector plays an important role in GDP growth of China. As a result forestry industry value output is increasing day by day. There is huge gap between demand and supply of timber projected in 2010. As a result it is necessary to develop fast growing, high yield forest following some specific policies. The ultimate goals of forestry are to construct or improve industry infrastructure, overall upgrade of forest industry structure, income improvement of forest employees and peasants, polices renewal and technology improvement, acceleration of forest processing with high-tech.