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      • KCI등재

        Uniaxial Compression Properties and Compression Fatigue Performance of Selective Laser Melted Ti–6Al–4V Cellular Structure

        Ming‑Wei Wu,Jhewn‑Kuang Chen,Mo‑Kai Tsai,Pei Wang,Tien‑Lin Cheng,Bo‑Huan Lin,Po‑Hsing Chiang,Annadurai Dhinakar 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.1

        The selective laser melted (SLM) Ti–6Al–4V cellular solid is a promising material in biomedical and other applications. The mechanical properties of the SLM Ti–6Al–4V cellular material are predominantly controlled by the design of the cellular structure. The objective of this study was to investigate the uniaxial compressive properties and compressive fatigueperformance of the SLM Ti–6Al–4V cellular solid with a new cuboctahedron unit cell reinforced by four diagonal strutsand two horizontal struts along the X and Y axes. The infuences of hot isostatic pressing (HIP) on the various mechanicalproperties were also examined. The results showed a smoother stress–strain curve and fewer stress oscillations in the HIPspecimen than in the SLM specimen. The HIP process slightly decreased the yield strength of the SLM sample from 55 to52 MPa. Under uniaxial compressive stress, the SLM and HIP specimens exhibited layer-by-layer fracture and diagonalshear fracture, respectively. Furthermore, the HIP treatment signifcantly increased the fatigue performance and improved thefatigue endurance ratio at 106cycles from 0.15 to 0.35. The HIP treatment contributed to several positive efects, includingphase transformation from brittle α′ to α + β, the elimination of strut porosity and residual stress, an increase in lath size,and a better combination of strength and ductility, thereby improving the fatigue performance. The efects of stress mode onthe fracture mechanism were also clarifed using in situ observation in combination with digital image correlation.

      • KCI등재
      • KCI등재

        錢鍾書關干比喩創作的理論體系

        陳明舒 한국중국문화학회 2003 中國學論叢 Vol.15 No.-

        전종서의 문학이론을 보면 비유에 관한 이론이 많다. 또한 그는 이러한 비유이론을 의도적으로 사용해서 문학 작품을 창조해왔다. 필자는 전종서의 비유에 관한 이론을 7가지로 정리해보았다. 1. '본체'와 '비유체' 사이에 유사점이 있으면 두 사물은 전체적으로 대응관계가 형성될 수 있다. 2. 비유의 최고의 효과를 얻기 위해서는 두 가지의 방법을 사용할 수 있는데, 그 첫 번째는 서로 상관이 없는 것에서 유사성을 밝히는 것이고, 두 번째는 아주 평범한 것에서 평범하지 않은 것을 찾아내는 것이다. 3. '본체'와 '비유체' 사이에 유사점은 연상에 의해 밝힐 수 있다. 4. '비유체'는 다양한 측면과 다양한 특징이 있다. 창작자는 자기의 주관적인 필요에 의해 '비유체'의 어떤 측면을 선택한다. 5. 창작자가 비유라는 수사방법을 통해 주관적인 감정을 표현할 수 있다. 6. 한 가지의 '본체'에 대해 많은 비유를 하는 것은 작가의 다양한 감각을 충분히 표현할 수 있도록 하기 위한 것이다. 7. 좋은 비유는 항상 표면적으로 보기에는 무관한 사물일지 모르지만 심리적인 측면에서 보면 유사성을 찾아낼 수 있다.

      • 녹음 구어 제시가 중도정신지체 성인여성의 목욕 능력 개선에 미치는 효과

        鄭如意,陳明聰,陳政見 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.2

        1. This study aimed to explore the effect of recorded auditory prompts on helping an adult with profound mental retardation to take bath independently. 「A-B-C-A-C」design, a kind of single-subject experiment was adopted. Three phases, baseline phase, intervention phase(B): auditory prompt, and intervention phase(C): recorded auditory prompt were included. A female with profound mental retardation participated in the experiment. It took over seven months to finishing the intervention. The results of the experiment indicated that auditory prompts, whether human auditory prompt or recorded prompt, could help the client to take bath more independently. The families of the client also regarded recorded auditory prompt was a feasible solution. Based on the result, there were some suggestions for the further research. 본 연구의 목적은 녹음 구어 제시를 이용해서 극 중도 지능장애 성인 여성 스스로 목욕 동작을 완성 할 수 있도록 도와주는 효과에 대한 연구입니다. 본 연구에 사용하는 연구법은 ⌜A-B-A-C-A-C⌟역 설계이다. 기선기의(A)개입一(B)인공구어제시 개입二(C)녹음 구어 제시로 나누어졌다. 실험기간은 모두 7개월 반이었다. 연구결과는 피 실험자가 스스로 목욕할 때와 비교했을 때 인공구어 제시와 녹음구어 제시는 모두 피 실험자가 목욕 동작을 완성 하는 데에 효과가 있는 것으로 나타났다. 이 외에도 녹음 구어 제시는 피 실험자 가족들도 받아들일 수 있다. 본 연구 결과에 근거해서 연구자들은 미래 응용과 연구에 대한 건의도 제출하였다.

      • KCI등재

        Prevention of Natural Flowering in Pineapple (Ananas comosus) by Shading and Urea Application

        Meng-Tzu Lin,Alfred Ming Chen1,Tzong-Shyan Lin,Ching-San Kuan,Ching-Lung Lee,Wen-Ju Yang 한국원예학회 2015 Horticulture, Environment, and Biotechnology Vol.56 No.1

        The year-round production of pineapple (Ananas comosus var. comosus) is often interrupted by natural flowering during winter in Taiwan. A stable and promising technique for preventing natural flowering is required. In this study, we have tested the effect of shading and urea application on the flowering of pineapple. Shading 90% of sun light(s) before mid-November delayed the natural flowering of pineapple and the delay was affected by the plant age. For pineapples planted less than 11 month before mid-November, applying 1% urea plus shading treatment (SN) completely inhibited natural flowering. All the flowering-inhibited plants could be forced to flower by applying calcium carbide. Long-term shading might result in a decreased number of fruitlets within a fruit. However, 6 weeks of recovery before forcing flowering was sufficient for plants to produce fruits with quality equal to that of the control plants. In winter, pineapple plants that were prone to flowering tended to accumulate more leaf starch and increase their C/N ratio. The SN treatment increased the leaf nitrogen concentration and thus effectively maintained a low leaf C/N ratio. Furthermore, flowering-inhibited plants exhibited a constantly low level of leaf starch during the winter and their flowering forced by calcium carbide did not accompany with leaf starch accumulation.

      • Tenofovir Alafenamide for Chronic Hepatitis B Patients with Advanced Fibrosis and Partial Virologic Responses to Oral Nucleos(T)Ide Analogues- Interim Report

        ( Ming-lung Yu ),( Ming-lun Yeh ),( Chi-yi Chen ),( Pin-nan Cheng ),( Ming-jong Bair ),( Jyh-jou Chen ),( Ching-chu Lo ),( Chi-ming Tai ),( Ching-yang Tsai ),( Kuo-chih Tseng ),( Chien-hung Chen ),( C 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

        Aims: Insufficient data regarding the treatment strategy for partial response to nucleot(s)ide analogue (NUC) raised the aim of investigating tenofovir alafenamide (TAF) switching for chronic hepatitis B (CHB) patients with advanced fibrosis and partial response to other NUCs. Methods: CHB patients with advanced fibrosis (stage 3 or 4) and under NUC (except TAF) therapy with detectable hepatitis B virus (HBV) DNA for >52 weeks are enrolled to TAF 25 mg/day for 96 weeks. The objectives are viral suppression, alanine aminotransferase (ALT) normalization and safety. Results: From Feb. 2019, 34 patients, including 21 (61.8%) with entecavir, 10 (29.4%) TDF and 3 (8.8%) lamivudine or adefovir, were enrolled (15 [44.1%] male, median 53 years). The fibroscan demonstrated a mean of 10.5 kPa (7 [20.6%] cirrhotic). Sixteen (47.1%) patients were HBV e antigen positive, seven (20.6%) had YMDD mutation. The median HBV DNA level declined from 68.5 IU/mL at enrollment to 27.0 IU/mL at 4<sup>th</sup> week, and undetectable at 12<sup>th</sup>, 24<sup>th</sup>, 36<sup>th</sup> week, respectively, after TAF switching, with undetectable HBV DNA in 14/34 (41.2%), 17/33 (51.5%), 15/25 (60.0%), and 9/15 (60.0%) patients and rate of ALT normalization (≤40 U/L) of 85.3%, 85.3%, 84.8%, 92.0%, and 80.0%, respectively, after TAF switching. (figure 1) Two patients experienced transient virological breakthrough and another one developed at the final time follow up. Serum creatinine and eGFR levels were stable after TAF switching (figure 1). Two patients early terminated including one at 12<sup>th</sup> week due to personal reason, and another one accidently died at 20<sup>th</sup> week due to acute heart attack. Others suffered only mild degrees of adverse events which were considered unrelated to treatment. Conclusions: The preliminary results demonstrated the TAF switching is effective and safe in viral suppression for CHB patients with advanced fibrosis and partial virologic responses to other NUCs.

      • SCIESCOPUSKCI등재

        Comparison of Milk-clotting Activity of Proteinase Produced by Bacillus Subtilis var, natto and Rhizopus oligosporus with Commercial Rennet

        Chen, Ming Tsao,Lu, Ying Yu,Weng, Tien Man Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.10

        This study investigated purification and milk-clotting activity of the enzymes produced by Bacillus subtilis var, natto and Rhizopus oligosporus compared with that of commercial rennet. The clotting time, viscosity, tension and microstructure of the curd and electrophoretic patterns of milk proteins were determined. The milk-clotting activity/proteolytic activity ratios (MCA/PA ratio) of B. subtilis, R. oligosporus and commercial rennet were also compared. The results revealed that the curd formed by the commercial rennet had the highest viscosity and curd tension and the shortest clotting time among the three enzymes. However, curd produced by Rhizopus enzymes was ranked as second. From the MCA/PA ratio and electrophoretogram analyses it could be concluded that the enzyme produced by B. subtilis had the highest proteolytic activity, while the commercial rennet had the highest milk-clotting activity. Observations of microstructures of SEM showed that the three-dimensional network for curd formed by commercial rennet was denser, firmer and more smooth. The milk-clotting activity, specific activity, purification ratio and recovery of the purified enzymes produced by both the tested organisms were also determined with ion exchange chromatography and gel filtration.

      • SCIESCOPUSKCI등재

        Association of a Single Nucleotide Polymorphism in the 5'-Flanking Region of Porcine HSP70.2 with Backfat Thickness in Duroc Breed

        Chen, Ming-Yu,Huang, San-Yuan,Lin, En-Chung,Hseu, Tzong-Hsiung,Lee, Wen-Chuan Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.1

        Higher environmental temperature affects the economic performance of pigs. Heat shock protein 70 has been shown to play an important role in thermoresistance. The purpose of this study was to assess the effect of a single nucleotide polymorphism in the 5'-flanking region of porcine HSP70.2 on growth performance in Taiwanese Duroc. The genotype of this nt 393 polymorphic site could be verified by digestion with Bsa WI restriction enzyme of a PCR product. Pigs with TT and TC genotypes have thinner backfats than those with CC type (p<0.05). The result suggested that the polymorphic Bsa WI site in the 5'flanking region of porcine HSP70.2 may be used as a marker for the early selection of ultrasonic backfat thickness in Duroc pigs.

      • SCIESCOPUS

        Realistic simulation of reinforced concrete structural systems with combine of simplified and rigorous component model

        Chen, Hung-Ming,Iranata, Data Techno-Press 2008 Structural Engineering and Mechanics, An Int'l Jou Vol.30 No.5

        This study presents the efficiency of simulating structural systems using a method that combines a simplified component model (SCM) and rigorous component model (RCM). To achieve a realistic simulation of structural systems, a numerical model must be adequately capturing the detailed behaviors of real systems at various scales. However, capturing all details represented within an entire structural system by very fine meshes is practically impossible due to technological limitations on computational engineering. Therefore, this research develops an approach to simulate large-scale structural systems that combines a simplified global model with multiple detailed component models adjusted to various scales. Each correlated multi-scale simulation model is linked to others using a multi-level hierarchical modeling simulation method. Simulations are performed using nonlinear finite element analysis. The proposed method is applied in an analysis of a simple reinforced concrete structure and the Reuipu Elementary School (an existing structure), with analysis results then compared to actual onsite observations. The proposed method obtained results very close to onsite observations, indicating the efficiency of the proposed model in simulating structural system behavior.

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