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      • KCI등재

        An FPGA-Based Modified Adaptive PID Controller for DC/DC Buck Converters

        Ling Lv,Changyuan Chang,Zhiqi Zhou,Yubo Yuan 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.2

        On the basis of the conventional PID control algorithm, a modified adaptive PID (MA-PID) control algorithm is presented to improve the steady-state and dynamic performance of closed-loop systems. The proposed method has a straightforward structure without excessively increasing the complexity and cost. It can adaptively adjust the values of the control parameters (Kp, Ki and Kd) by following a new control law. Simulation results show that the line transient response of the MA-PID is better than that of the adaptive digital PID because the differential coefficient Kd is introduced to changes. In addition, experimental results based on a FPGA indicate that the MA-PID control algorithm reduces the recovery time by 62.5% in response to a 1V line transient, 50% in response to a 500mA load transient, and 23.6% in response to a steady-state deviation, when compared with the conventional PID control algorithm.

      • SCIESCOPUSKCI등재

        An FPGA-Based Modified Adaptive PID Controller for DC/DC Buck Converters

        Lv, Ling,Chang, Changyuan,Zhou, Zhiqi,Yuan, Yubo The Korean Institute of Power Electronics 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.2

        On the basis of the conventional PID control algorithm, a modified adaptive PID (MA-PID) control algorithm is presented to improve the steady-state and dynamic performance of closed-loop systems. The proposed method has a straightforward structure without excessively increasing the complexity and cost. It can adaptively adjust the values of the control parameters ($K_p$, $K_i$ and $K_d$) by following a new control law. Simulation results show that the line transient response of the MA-PID is better than that of the adaptive digital PID because the differential coefficient $K_d$ is introduced to changes. In addition, experimental results based on a FPGA indicate that the MA-PID control algorithm reduces the recovery time by 62.5% in response to a 1V line transient, 50% in response to a 500mA load transient, and 23.6% in response to a steady-state deviation, when compared with the conventional PID control algorithm.

      • Fruit fly nutrition and proteomics

        Chiou Ling Chang 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.10

        Fruit fly is one of the most important pests for vegetables and crops worldwide. Since 1895, four species of fruit flies has invaded into Hawaii. In 2000, a group of scientists from Hawaii has initiated and implemented an area wide pest management program to suppress fruit fly population in Hawaii. Six techniques developed within the program has been transferred to many countries that have the fruit fly problem. Four techniques (monitoring, sanitation, bait spray, and male annihilation) are readily done by farmers. The other two techniques (sterile insect release and augmentative parasitoid release) involve mass fruit fly stock. Sterile insect technique (SIT) used in sterile insect release requires continuous mass rearing. Current mass rearing system has been satisfactory for rearing need. However, there are problems such as pesticide contamination of supporting material, spent diet management, labor intensive, and space issue. USDA-Agricultural Research Service looked for alternatives. In 2004, a novel fruit fly liquid diet has been developed. The core of this diet is using an inert substance (sponge cloth) to replace biological supporting material for mill feed (wheat product). During this diet development process, we have observed that fruit fly performance changes associate with the change of diet components. One of the most significant components is wheat germ oil. Larval diet supplemented with wheat germ oil (WGO) causes physiological reactions, such as increased fecundity and fertility, in some insects. Although the impact of WGO on insect physiology is important, the mechanisms of these actions are poorly understood. In this presentation, we will confirm our hypothesis that the addition of WGO to medium developed for larval oriental fruit flies modulates gene expression in the corresponding adults and further to identify when and how these gene expressed during different life cycle stages. We separately reared larvae of Bactrocera dorsalis on diets lacking or supplemented with WGO, and analyzed for expressed proteins in the resulting adult males and females by 2D-electrophoresis. Analysis of the gels revealed significant changes in expression levels of >70 proteins, 64 of which were identified by mass spectrometric analysis on MALDI-TOF/TOF. Apparent changes in expression levels for 6 of these proteins were confirmed by quantitative real-time PCR, showing that the changes in mRNA expression were reflected in changes in protein expression. These findings support the hypothesis that one mechanism of WGO actions in insect nutrition is the modulation of gene expression. Our goal is to identify molecular markers that serve as early indicators of the quality of insect culture media. Markers of deficient culture media will increase the efficiency of developing optimal systems for mass rearing beneficial insects and some pest species because decisions on culture media quality can be made without waiting through one or several life cycles.

      • Improvement of Bone Mineral Density and Markers of Proximal Renal Tubular Function in Chronic Hepatitis B Patients Switched from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide

        ( Tse-ling Fong ),( Brian Lee ),( Andy Tien ),( Mimi Chang ),( Carolina Lim ),( Ho S. Bae ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: Tenofovir alafenamide (TAF) is a novel prodrug that re-duces tenofovir plasma levels by 90% compared to tenofovir disoproxil fumarate (TDF), resulting in decreased bone mineral density (BMD) loss and renal toxicity. We aimed to study changes in BMD and markers of renal function of chronic hepatitis B (CHB) patients previously treated with TDF who were switched to TAF. Methods: This was a prospective single-arm open-label study of 75 CHB patients treated with TDF 300 mg daily who were switched to TAF 25 mg daily and followed for 24 weeks. All patients had been treated with TDF for at least 12 months and had HBV DNA < 21 IU/mL at the time of switch. BMD and markers of renal function were taken on the day of switch and repeated after 12 and 24 weeks of TAF treatment. Results: BMD significantly increased after switch from TDF to TAF from baseline to week 12 and remained stable at week 24. Mean percent changes from baseline to week 12 in hip and spine BMDs significantly increased (+ 12.9% and +2.4%, respectively). There were significantly more patients with gains in hip (86%) or spine (76%) BMD than patients who experienced loss (11% and 25%, respectively). No significant change in BMD was seen between week 12 and 24. There was no significant difference in eGFR<sub>CG</sub> from baseline to week 24. Significant improvement was observed in urinary beta-2 micro globulin/creatinine ratio between baseline and week 12 that remained through week 24 (median change from baseline to week 12 and 24; 1.5, 1.0 and 1.1 mcg/g respectively; P<0.01). Similar changes were observed with retinol binding protein/creatinine ratio at from baseline to week 12 and 24 (median change from baseline to week 12 and 24; 1.7, 1.3 and 1.4 mcg/g respectively; P<0.01). There was significant increase in fractional excretion of phosphate from baseline to week 24 (11.9 to 14.0; P<0.05). Phosphate threshold for renal tubular reabsorption decreased from baseline to week 12 (2.8 to 2.6 mg/dL). Conclusions: Switching from long-term TDF to TAF among CHB patients was associated with significant improvement in BMD and some markers of proximal renal tubular function. There was no improvement in urinary phosphate handling after the switch which suggests TDF has a direct effect on bone metabolism that is reversible. Longer term and larger studies are needed to confirm these findings.

      • KCI등재

        APPLICATION OF FUZZY LOGIC IN THE CLASSICAL CELLULAR AUTOMATA MODEL

        Chang, Chun-Ling,Zhang, Yun-Jie,Dong, Yun-Ying 한국전산응용수학회 2006 Journal of applied mathematics & informatics Vol.20 No.1

        In [1], they build two populations' cellular automata model with predation based on the Penna model. In this paper, uncertain aspects and problems of imprecise and vague data are considered in this model. A fuzzy cellular automata model containing movable wolves and sheep has been built. The results show that the fuzzy cellular automata can simulate the classical CA model and can deal with imprecise and vague data.

      • KCI등재

        Two Transition Metal Complexes: Magnetic Properties and Treatment Effect via Focused High-Intensity Ultrasound on Alzheimer’s Disease

        Chang-Lu Huo,Ting Yu,Cai-Ying Pei,Ling-Ling Liu,Ying-Rui Zhang,Ying-Li Zhang 한국고분자학회 2021 Macromolecular Research Vol.29 No.5

        Two novel coordination polymers (where Cu for the complex 1 and the Co for the complex 2) with distinct transition metal ions containing 4-(3,5-dicarboxylphenyl)-2- methylpyridine (H2L), the pyridyl-dicarboxylic acid ligand, have been produced under the solvothermal reaction conditions, and the two compounds’ performances and architectures were also characterized. The chemical formulae determined of two complexes are respectively [Cu(L)(H2O)]·H2O (1) and [Co3(L)2Cl2(H2O)2]·2H2O (2). Complex 1 exhibits a 2D network with a (3,6)-connected kgd topology based on the dinuclear [Cu2O2] units. In complex 2, the linear trinuclear [Co3(μ-Ocarboxylate)2(COO)2Cl2] units with mixed carboxylate and μ-Cl triple bridges are cross-linked by the L ligands into a 3D framework with a (3,6)-connected rtl topology. The complexes’ magnetic performances reflected that between consecutive metal ions, there exists the antiferromagnetic coupling. Their treatment activities on Alzheimer's disease (AD) via focused high-intensity ultrasound were evaluated. Firstly, the Annexin V-fluorescein isothiocyanate/propidium iodide staining was implemented for the assessment of the apoptotic neurons percentage after compounds treatment. Next, the Aβ accumulation in the neurons was also detected via employing the western blotting assay.

      • KCI등재

        Structure and Performances of xLiFePO4/C·(1 − x)Li3V2(PO4)3/C Cathode for Lithium-Ion Batteries by Using Poly(vinyl alcohol) as Carbon Source

        Chang-ling Fan,Wei-hua Zhang,Tao-tao Zeng,Ling-fang Li,Xiang Zhang,Shao-chang Han 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.11

        Poly(vinyl alcohol), whose pyrolysis carbon possesses high conductivity of 8.88 × 10−1 S/cm, was used to synthesize xLiFePO4/C·(1 − x)Li3V2(PO4)3/C cathode. It was characterized by X-ray diffraction, scanning electron microscopy, conductivity, cyclic voltammetry, and galvanostatic charge and discharge experiments. Results show that LiFePO4/C and Li3V2(PO4)3/C coexists in the cathode. The particles sizes of 0.75LiFePO4/C·0.25Li3V2(PO4)3/C (x = 0.75) are much smaller than 100 nm due to the role of poly(vinyl alcohol). Its conductivity is 8.79 × 10−2 S/cm. The oxidative and reductive peaks in cyclic voltammetry are sharp and symmetrical. Their low potential gaps indicate that the extractions and insertions of lithium ion possess excellent reversibility. Its discharge capacities at 1 and 5 C are 141.1 and 100.1 mAh/g. The more Li3V2(PO4)3/C in cathode results in the deterioration of electrochemical performances due to its low theoretical capacity. It is concluded that poly(vinyl alcohol) is an effective carbon source in the preparation of xLiFePO4/C·(1 − x)Li3V2(PO4)3/C composite cathode with excellent performances.

      • KCI등재후보

        Relationship between the FRAX® score and falls in community-dwelling middle-aged and elderly people

        Ling-Chun Ou,Yin-Fan Chang,Chin-Sung Chang,Ting-Hsing Chao,Ruey-Mo Lin,Zih-Jie Sun,Chih-Hsing Wu 대한골다공증학회 2016 Osteoporosis and Sarcopenia Vol.2 No.4

        Objectives: Falls is a risk factor for fracture. The FRAX® predicts fractures. Whether the FRAX® is associated with fall in both gender is inconclusive. The aim of our study is to evaluate the association between FRAX scores and falls. Methods: The cross-sectional study set from 2009 to 2010 included 1200 community-dwelling people who were systematically sampled in central Taiwan. The 1200 participants (men: 524; women: 676; ?40 years old) completed questionnaires about socioeconomic status; lifestyle; medical and fall history were completed. FRAX scores with and without bone mineral density (BMD) were calculated by using the Taiwan calculator. Results: A total of 19.8% participants fell down. Binary regression models showed that diabetes mellitus history (OR: 1.61; 95% CI: 1.03e2.52), the FRAX without BMD in a continuous major score (OR: 1.06; 95% CI: 1.03e1.09), continuous hip score (OR: 1.11; 95% CI: 1.05e1.16), categorical major score ? 10% (OR: 1.81; 95% CI: 1.25e2.61), and categorical hip score ? 3% (OR: 1.80; 95% CI: 1.30e2.50) were independent risk factors for falls. FRAX with BMD in a continuous major score (OR: 1.04; 95% CI: 1.02e1.06), continuous hip score (OR: 1.06; 95% CI: 1.02e1.09), categorical major score ? 10% (OR: 1.52; 95% CI: 1.09e2.12), and categorical hip score ? 3% (OR: 1.53; 95% CI: 1.13e2.09) were also independent risk factors. Conclusions: We concluded that FRAX® scores with and without BMD were unanimously correlated with falls in community-dwelling middleaged and elderly males and females.

      • Study on Simulation Analysis of Reduce Speed Effect for Wind Nets in Front of Crop

        ( Cheng-chang Lien ),( Zhu-yun Yeh ),( Wei-ling Sun ),( Jeng-liang Lin ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Due to frequent strong winds from its geographical location in Taiwan, which caused serious damage to vegetables and fruit trees, leading to a large loss of agricultural production. Wind nets can be used to reduce the wind speed in front of fruits and vegetables in order to reduce the impact of wind speed. The purpose of this study is to use Computational Fluid Dynamics(CFD), CFD simulation Software was used to simulate wind tunnel experiments with wind nets before fruits and vegetables to understand the wind tunnel with different ventilation rates under certain wind speed 40 m/s, to simulate the change of wind speed and the distribution of flow field behind the wind nets, Analyze and analyze the change of wind field and the effect of reducing the wind. The size of the wind net was 12m<sup>*</sup>6m. According to the CFD simulation results, when the strong wind blows through the wind nets, a negative pressure zone will be generated at a horizontal distance of 0h to 10h in the windshield leeway, and the height of the negative pressure zone will gradually decrease as the horizontal distance increases. The height of the negative pressure zone also decreases with the increase of the ventilation rate of the windbreak. In addition, the analysis results show that the ventilation rate of 40% of the windbreak, the negative pressure vortex gradually disappear, and have the best effect of reducing the wind.

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