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      • KCI등재

        가구 및 주거의 변화와 새로운 주택공급 방안의 모색

        장세훈(CHANG Se-Hoon) 지역사회학회 2007 지역사회학 Vol.9 No.1

        최근의 대규모 주택공급으로 주택 부족 문제는 많이 해소되었지만, 주택문제는 형태만 달리한 채 여전히 지속되고 있다. 이러한 점에 주목해서 이 글은 새로운 주택 문제의 현황을 살피고 그 대처 방안을 모색하고자 한다. 이를 위해 인구 및 주택 총조사 자료를 바탕으로 최근 사반세기 동안의 가구 구성 및 주거 실태의 변화와 주택 공급 추이를 살펴보고자 한다. 분석 결과 지난 25년간 가구 구성 및 주거 실태가 크게 바뀌었다. 우선 가구 수가 크게 늘었을 뿐 아니라 1인 가구, 한 부모 가구 등이 새로운 가구 유형으로 자리 잡았다. 또 주거 양식에서도 아파트 비중이 크게 늘어나고, 주거빈곤 가구가 격감하고 있다 주택 공급 차원에서도 주택 건설이 활발하게 이루어져 주택보급률이 100%를 넘어서고 신규 주택의 규모가 갈수록 커지는 등, 많은 변화가 일어났다. 이처럼 가구 규모가 줄고 세대 구성이 단출해지는데, 공급 주택의 규모는 증가 일로에 있어, 주택 과소비 및 미분양이 문제되고 있다. 또 다양한 가구 구성을 감안하지 않은 채 ‘표준 주택’이 획일적으로 공급되어, 주택 수급의 불일치 문제가 제기되고 있다. 더 나아가 취약 가구의 주거 불안 문제는 완화될 조짐을 보이지 않고 있다. 가구-주택간 부조응에서 비롯된 이 같은 주택 문제를 해소하기 위해서는 물량 위주의 주택공급 방안에서 벗어나, 주택 수요자의 사회적, 인구학적 변화에 관심을 갖고 주택 공급 방식을 다변화하면서 취약 가구의 주거 빈곤을 완화시키려는 노력이 뒤따라야 할 것이다. Massive housing construction since 1990s smoothed out housing shortage problems, but housing problems in general continue only to change their appearances. Focusing on this fact, this paper aims to examine the new housing problems and explore the policy responses. For this study, I will discuss the trends of household composition, housing conditions and housing provisions, based on the population and housing census data in 1990-2005. According to this study, household composition and housing conditions greatly changed for 25 years. The number of households was remarkably increasing and new household types like one-person households, single parents households became established. The proportion of apartment was beyond half of total housings and housing-poor households were decreasing swiftly. And the massive housing construction resulted in ‘ the age of housing supply rate 100%’ and the size of new housings was continuously expanding. Therefore the decreasing household size and the simplified household composition collide with the increasing housing size. It becomes the cause of housing over-consumption and accumulation of unsold apartments. And the standardized housing construction paying no regard to the various household compositions leads to the disparity between housing demand and supply. In addition to this, the socially weak households are still experiencing housing insecurities. In order to solve these housing problems resulting from household-housing inconsistencies, we should escape from housing supply-side strategy and pay more attention to its demand-side, especially consumers' social and demographic change. And we should make an effort to diversify housing types and alleviate the housing-poverty conditions of the socially weak house holds.

      • 알코올 투여로 온 흰쥐의 혈액성분의 변화와 간조직 손상과의 상호관계에 관한 연구

        조만희,김창세 순천향대학교 1986 논문집 Vol.9 No.2

        The white rats were divided by 3 groups; 0.6g(group A), 1.8g(group B) and 4.8g(group C) of alcohol per kg of body weight. The ethanol has been administered to the stomach with a polyethylene catheter using 20% ethanol solution for 30 days. In 5 day interval from the begining, the white rats were sacrificed to collect sample for blood analysis and histopathological observation. And the following results were obtained. 1. The most variable changes of blood components to be influenced by alcohol administration were; alcohol concentration, activities of liver ADH and GOT, numbers of RBC and WBC, amounts of triglyceride and total cholesterol and α₂-globulin fraction. 2. The liver histopathological changes, depending on the amounts and feeding days from the alcohol administration, were observed; normal finding on 1st to 10th and after then mild ballooning degeneration, necrosis of hepatic parenchymal cells in portal tract, mild infiltration of lymphocytes and fats degeneration. 3. The interrelationship between changes of blood components and histopathological damage of liver were coincide on 10th to 20th in the aspects of remarkable changes. From the above summary the amount and duration of ethanol-administration were influenced on changes of blood components and histopathological findings of liver while the early period usually 1st to 10th day was observed no more pathological changes but after then significants changes observed. From the above result there were suggested that the alcohol retaining in the body in a long period were results to appear in biochemical metabolic change.

      • 알코홀이 r-GTP 활성에 미치는 인삼의 영향

        이상한,조만희,신경현,김창세 순천향대학교 1989 논문집 Vol.12 No.3

        This study was carried out to investigate the effects on the changes of the r-glutamyl transpeptidase activity of ethanol-administered white rats. There was classified into group; ethanol treated group(group A), ethanol treated group which was pretreated with ginseng extract(group B), ginseng extract treated group(group C), and ginseng extract treated group which was pretreated with ethanol(group D). White rats of four groups were treated with combined 1% ginseng extract and / or 20% ethanol for 30 days, and were measured the changes of r-GTP activity on the serum, hepatic and renal tissue sample collected at 5 days interval. Following results have been obtained. 1. The changes of serum r-GTP activity were significantly decreased in ethanol treated group B which was pretreated with ginseng extract than in ethanol treated group A. The values were highly significant at the 20th day of feeding. 2. The changes of hepatic r-GTP activity were more increased in group A and decreased in group D. The values were found significantly lowest in 10th and highest in 5th days. 3. The changes of renal r-GTP activity were more increased in group A and decreased in group D. The values were significantly highest in 10th and lowest in 20th days. Based on these results it was found that the changes of r-GTP activity between serum and hepato-renal tissue were exist and the protective action of ginseng against alcohol degradative effects was noted.

      • KCI등재

        측두하악관절 골관절염 환자의 진단에서 Cone Beam 전산화 단층촬영의 유용성

        노창세,정연화,태일호,고명연,안용우,Roh, Chang-Se,Jung, Yun-Hoa,Tae, Il-Ho,Ko, Myung-Yun,Ahn, Yong-Woo 대한안면통증구강내과학회 2009 Journal of Oral Medicine and Pain Vol.34 No.1

        This study is designed to assess Relationship between clinical diagnosis of Temporomandibular Joint Disorder and diagnostic finding of Cone Beam Computed Tomography(CBCT) The author performed clinical examination for TMD Patients who visited Orofacial pain clinic, Jin-ju ooo Dental office. CBCT(Cone beam computed tomography) was taken for 190 joints in 95 subjects. A Oral medicine and Oral radiologist evaluated CBCT each other. then we compared with that result, Condyle bony changes were classified by no bone change, flattening, erosion and osteophyte. The obtained results were as follow: 1. The Kappa index of the diagnosis between oral medicine and oral radiogist were high, the index of diagnosis by degenerative joint disease were more higher. 2. The Kappa index of panoramic view and CBCT was low, more condylar bone chages were observed by CBCT diagnosis 3. Condylar bone changes of the 54.2% of non-DJD group clinicaly was observed by CBCT diagnosis and no bone changes of the 15.3% of DJD group.was observed by CBCT 4. TMJ pain was associated with erosion of condyle bone change of TMJ. Crepitation and longest duration of TMD were associated with osteophytic bone change.

      • 알코올 및 인삼액이 효소활성도에 미치는 영향에 관한 연구

        신경현,조만희,김창세 순천향대학교 1994 논문집 Vol.17 No.2

        This study was investigated for the change of r-GTP, CPK activity and CPK-isoenzyme by alcohol and Ginseng administration, The normal white S.D rats were classified with four groups; ethanol treated was group A, ethanol pretreated group combined pretreated with Ginseng extract was group B, Ginseng extract treated was group C, and Ginseng extract treated group combined pretreated with ethanol was group D. The white rats of four groups were treated with 20%, 30%, 40% ethanol and/or 1% Ginseng extract. Then enzyme activities such as r-GTP, CPK and CPK-isoenzyme had been measared in serum, hepatic, and renal tissues. The sample was collected by 5 day intervalus for 25 days. The following results were obtained. 1. The changes of serum r-GTP activities were significantly increased in ethanol-treated group, decreased in Ginseng-treated group. 2. The changes of hepatic r-GTP activites were significantly increased in ethanol-treated group, decreased in Ginseng-treated group. 3. The changes of renal r-GTP activites were significantly increased in ethanol-treated group, decreased in ginseng-treated group. 4. The changes of serum CPK activites were significantly increased in ethanol-treated group, decreased in ginseng-treated group. 5. The changes of hepatic and renal tissue CPK activites were not significant. 6. The changes of serum and hepatic tissue CPK-isoengyme were significantly increased in ethanol-treated group, decreased in ginseng-treated group combined pretreated with ethanol. 7. The changes of CPK-isoengyme, CPK 1 and CPK 2 were not significant.

      • Carotenoids 식이와 알코올이 혈액학적 성분과 간조직에 미치는 영향에 관한 연구

        조만희,김연선,이상한,우기민,장예진,김창세 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

        Alcohol is well known agent which can damage the human tissues such as liver via stimulating lipid peroxidation and storage, denaturation of macromolecules, and inhibiting protein metabolism. On the other hand, carotenoids in addition to vitamins A, C, E and lipoic acid, play important roles in protecting these oxidative damages as well as preventing the production of free radicals. This study was carried out to elucidate the precise effects of alcohol administration into rats on the antioxidative functions of dietary carotenoids and isolated β-carotene, and to find out any parameters to uncover more detailed biochemical mechanisms of these agents. For these purposes, two different approaches were performed: 1) examination of the changes in hematological parameters (e.g., total proteins, A/G ratio, ALT/AST et. al) and statistical correlations among inter- and intragroups, 2) examination of the histopathological changes by an electron microscope. The results were analyzed and summarized as following; (1) Carrot diet for one week caused a slight increase in albumin. A/G ratio and AST levels, and a slight decrease in ALT, ALP, BUN and uric acid levels. Two-week alcohol administration following carrot diet increased total proteins, albumin A/G ratio and BUN levels. However, both groups were shown to have little significant changes in cholesterol concentrations. (2) Cheese diet for one week caused a significant increase in total proteins, albumin, AST, ALP, uric acid and total cholesterol levels, and a significant decrease in A/G ratio and glucose concentrations. However, two-week β-carotene diet following cheese intake increased total proteins albumin, A/G ratio, BUN and total cholesterol levels, whereas AST, ALT, ALP and uric acid levels were decreased. (3) Alcohol administration for one week caused an increase in AST activities and a decrease in total proteins, albumin, ALT, ALP and BUN levels. A successive β-carotene diet following alcohol administration increased total proteins, albumin, ALT, ALP and BUN levels, whereas decreased AST and uric acid levels. However, there were not significant changes in A/G ratio, glucose and total cholesterol levels in both groups. (4) β-carotene diet for one week caused a slight increase in albumin, glucose, AST and uric acid levels, and a slight decrease in ALP and BUN levels. Two-weeks alcohol administration following β-carotene diet increased albumin, glucose, BUN and total cholesterol levels, whereas decreased AST, ALT, ALP and uric acid levels. (5) Although the pathological investigation on the liver did not reveal significant changes, cheese diet group (CH-BC/1-CH) was shown to have some lipid deposits. Some results were unexpected and different from typical hematological changes shown by other researchers. Nonetheless, these results strongly suggest that the liver damage or hepatism caused by alcohol intake affects many kinds of biochemical metabolisms, which results in significant changes in many hematological parameters. In addition, dietary carotenoid and isolated β-carotene were shown to have protective roles against the biochemical changes by alcohol intake.

      • 金長生의 修己論

        張世浩 慶星大學校 1988 論文集 Vol.9 No.1

        Kin Cnang-Saeng's theory of self-discipline is characteristic of "Shindok". It is based on his hard self-discipline ; according to Kim Chang-Saeng's attitude man cannot act without considerations of self-discipline. Man should practice moral principles to " Tien-Li." The bases of such act are performed under complete recognition of "Li" through "Ching" and "Tsun-yang." And it is equivalent to Kim Cnang-Saeng's attitude toward the study of philosophy. Unlike scholars before him, he particularly regards "Hsiao-Hsueh" and "Chia-Li" as primary sources. He thinks that man can achieve moral act through internal self-discipline directly coming from pracitcal act. This self-discipline of Kim Chang-Saeng's may result from complete "Cnontong" (keeping orthodoxy).

      • 담배 박각시나방 Manduca sexta의 계획된 세포죽음동안의 Proteasome의 변화

        이구봉,우기민,조만희,이상한,장예진,김창세 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

        모든 진핵세포의 주요 단백질 분해요소인 proteasome은 변성되거나 상해된 불필요한 단백질을 제거할 뿐만 아니라, 세포주기를 비롯한 다양한 대사과정들의 주요 효소들을 필요 시 적절히 분해함으로써 항상성을 유지시키는 필수적인 효소로 잘 알려져 있다. 또한 proteasome은 특정 포유동물 조직의 계획된 세포죽음(programmed cell death 또는 apoptosis)와 밀접하게 관련되어 있다고 보고된 바, 본 연구에서는 담배 박각시나방(Manduca sexta)의 변태과정에서 일어나는 마디간 근육(intersegmental muscle)의 급격한 파괴과정동안의 proteasome의 변화양상을 발현 및 단백질 분해활성을 중점으로 조사하였다. 정상근육과 파괴직전의 근육으로부터 proteasome을 분석한 결과 단백질 분해활성이 최소한 6배 이상 증가하였으며, proteasome의 주요 구성성분들의 발현 변화를 각각의 항체(antibody)를 이용하여 조사한 결과 세포죽음 직전에 급격히 증가함을 보였다. 이러한 구성성분들의 발현증가가 proteasome 복합체 형성을 통해 활성의 증가를 일으키는지 조사한 결과, 세포내에서 실질적으로 단백질 분해활성을 담당한다고 여겨지는 26S proteasome(2,000 kDa)의 위치에서 커다란 활성의 변화와 구성성분의 증가를 볼 수 있었다. 따라서, 담배 박각시나방의 계획된 세포죽음 현상은 특정 호르몬의 신호에 의해 proteasome의 발현이 급격히 증가하여 26S proteasome의 복합체 형태로 세포 내 대부분의 단백질들을 분해함으로써 30시간이내 근육조직을 완전히 소멸시키는 것을 알 수 있었다. 한편, proteasome을 구성하는 특정 구성성분의 과다 발현이 세포의 단백질 분해현상에 어떠한 영향을 미치는 지 조사하기 위하여 쥐의 fibroblast cell에 26S proteasome의 ATPase 구성성분인 m56 유전자를 삽입한 후 세포의 추출물로부터 proteasome의 양과 활성의 변화를 관찰하였다. Proteasome을 초원심분리로 추출하여 관찰한 결과, 담배 박각시나방의 경우와는 달리 유전자 삽입 세포는 모든 실험에서 정상 세포와 전혀 차이를 보이지 않았다. 이 결과로부터 세포의 생명 유지에 필수적이고 매우 다양한 기능을 가진 proteasome은 40여개의 구성성분들의 발현이 매우 정교하게 조절되고 있으며, 특정 세포죽음 자극(apoptotic signal)이 왔을 때 일련의 구성 성분들의 발현과 26S proteasome 복합체 형성이 증가함으로써 그 기능을 수행하는 것을 알 수 있으며, 보다 자세한 연구는 비정상적 단백질 분해나 세포죽음을 동반하는 여러 질환들의 원인과 현상을 규명할 수 있으며, 또한 그 활성을 조절함으로써 궁극적인 치료의 방향도 제시 가능할 것으로 기대된다.

      • KCI등재
      • 에타놀 정맥투여 고양이의 뇌압 변화에 관한 연구

        김세훈,장석종,박해근 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

        It has been well known that respiratory status has affected the intracranial pressure by' changing the brain blood flow, and also ethanol has affected the respiratory system by inhibiting the respiratory center and has affected cardiovascular system by inhibiting the cardiac performance and decreasing the total peripheral resistance. However, effect of ethanol on intracranial pressure has not been studied satisfactorily. Thus, following experiment was performed to examine the change of the intracranial pressure after ethanol administration in the cats. Ethanol was infused intravenously by lg ethanol per kg body weight for 15 minutes. Intracranial pressure was measured through balloon inserted between epidura and skull. Arterial blood pH, Po_2, Pco_2, ethanol concentration were measured. The results obtained are surnmerized as follows. Blood ethanol concentration increased by linear and peaked at 15 minutes(blood ethanol concentration was 409±31 mg%). Po_2, Pco_2. and pH at 15 minutes were 80. 3±5. lmmHg, 49.2±3.3mmHg and 7.24 =0.015 respectively. Blood pressure began to decrease and arterial pulse pressure began to increase at 10 minutes and more and more at 15 minutes respectively. Intracranial pressure began to increase at 10 minutes (blood ethanol concentration was 316±33 mg%) and peaked as 168.7±11.4% contrast to control at 15 minutes and also amplitude of intracranial pulse wave was increased. From the above results, it was suggested that intracranial presssure and amplitude of intracranial pulse wave were increased significantly by inhibiting respiratory center and thereby dilatating cerebral blood vessels with intravenous ethanol administration.

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