종합건강 피검진자의 건강증진 행위와 관련요인

이진희,박재순,서순림 여성건강간호학회 1999 여성건강간호학회지 Vol.5 No.3

The purpose of this study was to identify the health promotion behavior and its related factors of persons who wanted a comprehensive health check-up in order to provide a basis for health education to promote health enhancing behavior. Study variables were induced from Pender's Health Promotion Model. The subjects were 160 persons who had a check-up at the health promotion center in a university hospital in Tae-Gu, between September 8 and 22. 1998. The following instruments were used in the study : Lee Tae Wha's Health Promoting Life-style Profile. Park Chaff Soon's Self-efficacy Instrument and Moon Jeong Soon's Perceived Benefit and Barrier Instrument. Data was collected by self-reporting questionnaire. Analysis of the data was done by SAS program, t-test, ANOVA and Pearson-Correlation Coefficient. The results of this study were as follows. 1. The average score for the health-promotion behavior was 104.64. In the subcategories, self-actualization showed the highest degree of performance and physical exercise showed the lowest degree of performance. 2. In the relation of general characteristics of subjects to the level of health-promoting behavior, the male, the married, the group with several symptoms showed a high level of health-promoting behavior. 3. The relationship between the degree of performance in health-promotion behavior and its correlates were as follows : Self-efficacy was positively correlated to health promotion behavior, while the perceived barrier was correlated negatively. But the perceived benefit did not show a significant correlation with health promotion behavior. Results suggest that the development of programs with strategies to strengthen doing physical exercise and concerning health, increase self-efficacy and exclude the barriers to health promotion is recommended to individuals seeking a comprehensive health check-up.

국산 알벨다졸(안젠탈^(�))의 臟內線蟲類에 대한 驅蟲效果

蔡鐘一,洪性台,孫運睦,李純炯 대한화학요법학회 1986 대한화학요법학회지 Vol.4 No.1

An anthelmintic trial of albendazole was carried out an total of 186 inhabitants of Namhaegun, Kyongsangnam-do. For this purpose they were examined for their intestinal parasites, by cellophane thick smear and/or anal swab techniques before and 2 weeks after anthelmintic treatment. The examinations revealed A. lumbricoides 5.9%, T. trichiura 26.9%, E. vermicularis 52.4%, Echinostomia sp. 0.02% and Taenia sp. 0.01%. The infected cases were treated with 400㎎ single dose of albendazola. The egg negative conversion rate(NCR) and the egg reduction rate(ERR) were calculated based upon the results of pre and post-fecal examinations. For Ascaris, NCR was 87.5%, ERR 97.1%, and NCR 51.1% and ERR 78.6% for Trichuris. NCR was 100% for Enterobius. Albendazole(Alzental) is regarded as one of recommendable anthelmintics for the nationwide mass treatment programme of intestinal nematodes especially for ascariasis.

녹차 Catechin이 Streptozotocin으로 유발된 당뇨쥐 심장에서의 항산화계와 Lipofuscin 함량에 미치는 영향

채영미,박모라,이순재 한국노화학회 1998 한국노화학회지 Vol.8 No.3

國産 Praziquantel (Cestocide^(�)의 無鉤條蟲 및 廣節裂頭條蟲에 對한 治療效果

蔡鐘一,孫運睦,洪性琮,李純炯,徐丙卨 대한화학요법학회 1985 대한화학요법학회지 Vol.3 No.2

Praziquantel(Cestocide^ⓡ), Korean product, was tested for its efficacy in the treatment of Taenia saginata and Diphylobothrium latum infection during the period from May 1983 to October 1985, A total of 30 patients were treated with 10~30㎎/㎏ single dose of praziquantel and purged with 20~30g of magnesium sulfate to recover the worms. The results were as follows: 1. The patients were 26 cases of T. saginata and 4 cases of D. latum and after the treatment all of them discharged tapeworm segments with or without their scolices. The scolex recovery rate was 43.3%(from 11 and 2 cases of T. saginata and D. Iatum respectively). 2. The follow[up examination for eggs and/or proglottides performed 2~3 months later or 11 out of 17 scolex-unidentified cases gave all negative results. From the results it is concluded that praziquantel(Cestocide^ⓡ) in 10㎎/㎏ single dose is highly effective in treatment of these tapeworm infections.

요꼬가와吸蟲症 治療에 있어서 Praziquantel(Distocide^(�))의 效果

李純炯,蔡鐘一,洪性琮,全英淑,徐丙卨 대한화학요법학회 1984 대한화학요법학회지 Vol.2 No.2

國産 praziquantel(Distocide^(ⓡ))의 요꼬가와吸蟲感染에 대한 治療效果를 알아보기 위하여 전라남도 강진군 탐진강 流域의 住民 중에서 68名의 蟲卵陽性者를 색출하고 體重당 100㎎/㎏의 praziquantel을 單回 투여한 후 70일에 追跡大使檢査를 실시하여 驅蟲效果를 判定하였다. 結果는 다음과 같다. 1. 총 45名의 追跡檢査者 중 41名이 蟲卵陰轉되어 91.1%의 治療率(care rate)을 보였으며 이들의 投藥前 E.P.G 合計가 125,600이었던 것이 投藥後 800으로 減少되어 99.4%의 蟲卵率을 보였다. 2. 驅蟲效果는 投藥前 感染强度(E.P.G)에 따라 다소 다른 것으로 나타났으며 輕感染者일수록 높은 效果를 보였다. 3. 藥劑服用에 의한 副作用은 2例에서 가벼운 頭痛이나 현기증을 호소한 이외에는 전혀 문제되지 않았다. 이상의 結果로 볼 때 國産 praziquantel(Distocide^(ⓡ)) 요꼬가와吸蟲症에 대하여 10㎎/㎏ 單回投與로 매우 우수한 驅蟲效果를 보이는 것이 立證되었고 效果, 投藥法, 副作用 등을 감안할 때 집단치료 약제로서 손색이 없을 것으로 생각되었다. Fraziquantel(Cistocide", Chinpoc:-g Pharm. Co). a 'croad spectrum anthelmintic zgzirs: tremato6es and cestodes, ~ 5 - i - a ~ tested for its efficacy In treatment of A!letclgonin.zis yok~govias infection. during the priod fron? Jzmsry t o Ajmi. 1984. A total of 68 egg ~ o s i t i r e cases TTES selected from the inhabitants of Kangjin-gun, South Choila Do, 2nd treated a i t h lOmg/kg ?x<:- weight of I;raziquar.te! in single dose. Among them 25 heavy infection cases were purged ~ i t l 20-20g of magnesium sulfzte(MIgS04) one hour after the treatrcent. Follow up stool exammztion was done after 70 days and the drug efficacy was estimated in terms of cure(=egg negati7-e conversion) and egg reduction rates. The results were as follows: 1. AIiong 45 follm- up cases 41 were cured(91.1% in cure rate) and the pre-treatment E.P. G.(eggs per gram of feces). 125,600, was reduced to 800 after the treatment(gg.4X in egg reduction rate). 2. The cure rates x-ere dependent upon the degiee of E.P.G.; the lower the intensity of infection before treatment, the higher the cure rate was obtained. 3. There x-ere nearly no side effects due t o drug administration except f o r slight degree of headache and dizziness in 2 cases. From these results, it is concluded that lOmg/kg single dose of praziquantel (Distocide") is highly recommendable in treatment of M. gokogawat infection.

구리- Chromazurol S 錯物形成과 구리의 吸光光度定量

黃在順,高錫梵 全北大學校 文理科大學 1975 論文集 Vol.2 No.-

Copper(Ⅱ) reacts rapidly with chromazurol S(CAS) (3"-sulpho-2", 6"-dichloro-3, 3'-dimethyl-4'-hydroxyfuchson-5, 5' dicarboxylic acid, sodium salt) in water-ethanol solution at pH 6.7 to form a blue solution of a 1:1 complex having abosorption peak at 590nm, The copper(Ⅱ)-CAS complex is stable for at least twelve hours. The system conforms to Beer's law. Optimum range for 1.00cm optical path is 1×10 exp (-6) to 1.3×10 exp (-5)M of copper(Ⅱ). The order of the additin of reagents has no effect upon the absorbance. The molar absorptivity at 590nm is 3.0×10 exp (4)liter mole^-1 cm^-1 and the sensitivity which give the absorbance of 0.001 is 0.0021 ug cm^-2. Among twelve kinds of metal ions only Sn(Ⅱ)and Bi(Ⅱ) ions seriously interfered with the determination. The composition ratio and the formation constant of the copper(Ⅱ)-chromazurol S complex have been evaluated from spectrophotometric data.

自然界의 放射性 落塵과 大氣中의 放射能 測定 및 未知 核種의 核種分析

이채순,하영숙 梨花女子大學校 藥學硏究所 1967 梨花藥學硏究 Vol.- No.8

Radioactivities being observed of the radioactive fallout and air-borne dust in the vicinity of Seoul area by the end window type Geiger Mu¨ller counter (Tracerlab, TGC-2 G.M. tube window thickness 1.8 mg/㎠), the daily variation of these radioactivities concentration in July 1967 were revealed to be similar. The radionuclide analysis of the unknown radioisotopes were undertaken by using of single channel radiation analyzer (Nuclear Chicago, Model 1820 A), and the Feather's method, the radiounclides Co^60 HF^181 were discriminated by former method and the P^32 by later method.

吸蟲症 및 條蟲症 治療에 있어서의 Praziquantel

李純炯,蔡鐘一 대한화학요법학회 1985 대한화학요법학회지 Vol.3 No.2

Praziquantel, a broad-spectrum anthelmintic against various kinds of trematodes and cestodes, was reviewed in terms of its pharmacokinetics, in vitro and in vivo effects on wormsi mode of action, clinical application and side effects. Orally administered praziquantel is absorbed rapidly though gastrointestinal tract, metabolized in the liver and excreted in urine and feces. It causes rapid contraction of worms and extensive vacuolization of their tegument and/or parenchymal layers, which results in the worm death. Such effects are known to be calcium(Ca^++)dependent. Clinically it can be used in the treatment of infections by liver flukes, lung flukes, intestinal flukes, schistosomes, adult and/or larval tapeworms. Various kinds of side effects may occur but they are usually mild and transient. Points to be further studied were discussed.

STZ 유발 당뇨쥐에서 시간에 따른 생리적 항산화계의 변화

이순재,양정아,김성옥,최정화,신주영,채영미,차복경 대구효성가톨릭대학교 응용과학연구소 1997 응용과학연구논문집 Vol.5 No.-

The purpose of this study was to investigate change of physiological antioxidative system according to the time in streptozotocin-induced diabetic rats. Sprague-Dawley male rats weighing 150±10gm were randomly assigned to one normal and five STZ-induced diabetic groups. Diabetic groups were classified to experimental period. Diabetes was experimentally induced by intravenous injection of 55 mg/kg of body weight of STZ in citrate buffer(PH 4.3) after 6 weeks feeding of three experimental diets. Animals were sacrificed at 0, 3, 6, 12, 18th days of diabetic states. 1. Activity of superoxide dismutase(SOD) in liver was increased in that of diabetic mellitus(DM) groups at 3th day but that of DM groups was not significant from 6th day according to period. Glutathion peroxidase(GPX) was significantly decreased in DM groups from 6th day 2. Reduced glutathione(GSH) contents in liver significantly decreased in diabetic groups from 3rd day compared with those of DM groups according to the period. Oxidized glutathione(GSSG) was higher from 6th day. GSH/GSSG ratio was significantly lower than that of normal group from 3rd day to all experimental period 3. Contents of vitamin E in liver of DM groups were significantly decreased compared with that of normal group from 6th day. 4. Lipid peroxide(LPO) contents in liver of DM groups were significantly increased compared with that of normal group from 3rd day. The present results indicate that STZ-induced diabetic rats were reduced by antioxidative defense system and taken by peroxidate damage in tissue compared with normal group from 3rd day or 6rd day after injection STZ. It lended to acceleration all diabetic groups but no significance according to the experimental time.

鑛産物工業分析法에 關한 定性實驗的硏究

黃在順 全北大學校 1957 論文集 Vol.1 No.-