http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Carreño (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
Santiago Sánchez-Beitia,Daniel Luengas-Carreño,Paulo B. Lourenço 한국강구조학회 2021 International Journal of Steel Structures Vol.21 No.6
The X-ray diff raction technique for determining residual stresses in construction steels has been commonly used in the international scientifi c community for decades. Taking advantage of the concepts on which the technique is based, the authors have previously calibrated and used the technique for the in situ determination of the stress states of metallic structures in service. This article presents an advance in the latter utility by means of the laboratory calibration of the X-ray diff raction technique in corrugated steel. The interaction between radiation and steel is complex, so, in the scientifi c community, it is considered pertinent to resort to empirical and experimental calibration processes. Two bars of corrugated steel were subjected to increasing tensile loads. The load states introduced in the testing machine were compared with those determined by X-ray diff raction. The correlation between the values of the loads applied and those determined by the proposed technique is excellent. The experimental conditions of the calibration tests are precisely detailed so that they are easily reproducible. This work represents a necessary fi rst step in employing the technique in the buildings or civil works.
-
Mixtures of Cellulose Fibers from Pineapple Leaves, Ionic Liquid, and Alkanolamines for CO2 Capture
María Fernanda Agudelo Hernández,Marisol Fernández Rojas,Franciele Bernard,Sandra Einloft,Luz Angela Carreño Diaz 한국섬유공학회 2020 Fibers and polymers Vol.21 No.12
Researchers around the world are looking for ways to improve or develop new technologies to mitigate theemissions of CO2 present in greenhouse gases. Amines are currently the most used substances to capture CO2. The ionicliquids (ILs), however, have also been considered promising materials. Recently, mixtures of ILs and amines have beenstudied for this purpose. The ILs are also being supported in solid matrices (polymers, zeolites, cellulose, and membranes) toobtain stable, easy to handle, and reusable materials. Cellulose fibers make a promising matrix, considering their affinity withCO2, renewable feature, and thermal, mechanical, and chemical stability. To improve the CO2 capture capacity by usingcellulose and the mixture of ILs and amines, we prepared mixtures of the ionic liquid 1-butyl-3-methylimidazoliumtetrafluoroborate [BMIM][BF4] and monoethanolamine or triethanolamine. Then, we dropped the mixtures on naturalcellulose fibers from pineapple leaves. This paper reports the characterization of the composite materials by FTIR, XRD,XPS, FESEM, and TGA-FTIR in order to evaluate their structure, composition, morphology, and thermal behavior. We alsoreport the CO2 sorption capacity at 25 °C and 25 bar as determined by the pressure-decay technique as well as the CO2selectivity using a CO2/CH4 mixture. We found that the fiber with an alkaline treatment containing 35 % of IL and 35 % ofTEA captures the highest amount of CO2 (141 mg of CO2/g of fiber) and that the mixture TEA/IL is more selective for CO2.
-
Chopra, A,O-Sullivan, I,Carr, J,Kim, T S,Cohen, E P Nature Publishing Group 2007 Cancer gene therapy Vol.14 No.6
In a prior report (Int J Cancer 2006; 119: 339–348), we described a new vaccination strategy for squamous cell carcinoma (SCC). The vaccine was prepared by transfer of unfractionated DNA-fragments (25 kb) from KLN205 cells, a squamous carcinoma cell line (DBA/2 origin; H-2<SUP>d</SUP>) into LM cells, a highly immunogenic mouse fibroblast cell line (C3H/He origin; (H-2<SUP>k</SUP>)). As only a small proportion of the transfected cell population was expected to have incorporated DNA segments that included genes specifying antigens associated with the squamous carcinoma cells, we devised a novel strategy to enrich the vaccine for immunotherapeutic cells. Enhanced immunity to squamous carcinoma was induced in tumor-bearing mice treated solely by immunization with the enriched vaccine, which translated into prolonged survival without toxicity. Here, we describe the characteristics of the cell populations infiltrating established squamous carcinomas undergoing regression in mice immunized with vaccines enriched for immunotherapeutic cells. The results indicated that CD8+ T cells were predominant and that T-regulatory cells (FoxP3+, CD4/CD25+, CD4/CD62L<SUP>high</SUP>, CD4/CTLA-4e) were relatively deficient in the regressing tumors. Inflammatory infiltrates were not detected in various organs and tissues of mice immunized with the DNA-based vaccine.Cancer Gene Therapy (2007) 14, 573–582. doi:10.1038/sj.cgt.7701040; published online 23 March 2007
-
Prevalence of tumor BRCA1 and BRCA2 dysfunction in unselected patients with ovarian cancer
( Roshni D Kalachand ),( Ciaran O’riain ),( Sinead Toomey ),( Aoife Carr¸ Bsc ),( Kirsten M Timms ),( Sharon O’toole ),( Stephen Madden ),( Mark Bates ),( John J O’leary ),( Noreen Gleeson ),( Dearbha 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.5
Objective The therapeutic benefits of poly(ADP-ribose) polymerase inhibitors highlight the need to evaluate BRCA1/2 defects in tubal/ovarian cancer (OC). We sought to determine the pattern and disease characteristics associated with tumor BRCA1/2 mutations and BRCA1 methylation in women with OC. Methods We obtained 111 OC specimens from 2 university hospitals and assessed BRCA1/2 mutations and BRCA1 methylation in tumor DNA. The frequency and pattern of BRCA1/2 defects were examined. Associations between patient/disease characteristics and BRCA1/2 defects were ascertained (Fisher’s exact test). Platinum-free interval (PFI), progressionfree survival (PFS), and overall survival (OS) based on the underlying BRCA1/2 defect were determined (Kaplan-Meier analysis [log-rank test]). Results We observed a BRCA1/2 dysfunction rate of 40% (28/70) in high-grade serous tubal/ovarian cancer (HGSC), including 14.3% BRCA1 methylation (n=10), 7.1% BRCA1 mutation (n=5), and 18.6% BRCA2 mutation (n=13). Defects in BRCA1/2 genes were associated with stage III/IV HGSC (BRCA1 methylation: P=0.005 [stage III/IV] and P=0.004 [HGSC]; BRCA1/2 mutation: P=0.03 [stage III/IV] and P<0.001 [HGSC]). Patients with BRCA1/2-mutated cancers showed improved OS (hazard ratio [HR], 0.65; 95% confidence interval [CI], 0.43-0.99; P=0.045) and a trend toward improved PFI (HR, 0.48; 95% CI, 0.22-1.06; P=0.07) and PFS (HR, 0.72; 95% CI, 0.51-1.03; P=0.07). No survival differences were observed between BRCA1-methylated and BRCA1/2 wild-type non-BRCA1-methylated cancers. Conclusion We observed a high tumor BRCA1/2 dysfunction rate in HGSC with a unique predominance of BRCA2 over BRCA1 mutations. While BRCA1/2 mutations conferred survival benefits in OC, no such association was observed with BRCA1 methylation.
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
