암세포주의 세포외기질단백에 미치는 Nocodazole의 영향

정병욱,김주영,이융창 대한해부학회 1997 Anatomy & Cell Biology Vol.30 No.5

정상 면역인에서 동시에 발생한 베체트병과 결핵성 림프절염 1례

이병욱 외 중앙대학교 의과대학 의학연구소 2011 中央醫大誌 Vol.36 No.1/2

Behçet's disease is an idiopathic systemic vasculitis which manifests with recurrent oral or genital ulcer, various skin lesions and ocular lesions. The strategies of treatment for Behçet's disease frequently include various immunosuppressants, such as systemic steroids, azathioprine, cyclosporine A, cyclophosphamide, and infliximab. These immunosuppressive agents attenuate the cell-medicated immunity of hosts and predispose them to the development of tuberculosis. Cases in which pulmonary tuberculosis, intestinal tuberculosis, and tuberculous meningoencephalitis are developed in Behçet's disease patients who had been taking immunosuppressive drugs, including corticosteroids, are frequently reported worldwide. However, no case has been reported in which tuberculous lymphadenitis was concurrently diagnosed with Behçet's disease, especially in a patient who is not under immunosuppressive therapy. We describe here the case of a 28-year-old woman presenting fever who was simultaneously diagnosed as having Behçet's disease and tuberculous cervical lymphadenitis.

합병증이 동반된 Meckel씨 게실 2례 보고

정병욱,박동일,이준희,서정욱,원유홍,김웅,신현종,권영무 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

합병증이 동반된 Meckel씨 게실을 가진 환자의 치료에 대한 필요성은 과정이 문제이다. 하지만 우연히 만나는 게실의 처치는 논란 중이다. 부수적인 게실 절제술(incidental diverticulectomy)의 제안자는 증상이 있는 게실의 외과적 처치는 중요한 이환 및 사망률은 지적한다. 이를 반대하는 사람들은 전 생애를 통해 합병증의 위험성이 낮게 나타나므로 필요가 없다고한다. 게실의 예방적 제거는 개복술시 우연히 발견 될 때 시행한다. 이는 남아있는 게실이 나중에 합병증을 일으키는 것보다 술후 합병증의 위험성이 매우 적음을 알 수 있다. 저자들은 합병증이 동반된 Meckel씨 게실 2예를 경험하였기에 문헌 고찰과 더불어 보고하는 바이다. The necessity for therapy with complicated Meckel's diverticular is a matter of course.However, management of the incidentally encountered diverticulum is controversial. Proponents of incidental diverticulectomy point to the significant morbidity and mortality rates of surgical treatment of symptomatic divenicular. Other authors base their opposition to incidental diveniculectomy on the low risk of complications developing during lifetime. Prophyillctic removal of the diveniculum is indicated when it is found incidentally at laparotomy, because there are few postoperative complications and the risk exists that the remaining diverticulum may be the cause of later complication. The 2 cases of complicated Meckel's diverticulum are reported with a brief review of literature.

좌각차단을 동반한 심부전증 환자에 실시한 양심실 심박조율기 치료 : 증례 보고

김찬욱,차태준,김성만,김민대,권성일,서수홍,최병주,주승재,이재우 고신대학교 의학부 2002 高神大學校 醫學部 論文集 Vol.17 No.1

Epidemiological studies suggest that 30-50% of patients diagnosed with symptomatic congestive heart failure(CHF) have electrocardiographic evidence of a major intraventricular conduction delay, which may worsen left ventricular systolic and diastolic dysfunction through asynchronous ventricular contraction and paradoxical interventricular septal wall motion. Biventricular pacing is an emerging therapy allowing simultaneous electrical stimulation of the both ventricles with an implantable pacing system and it improves hemodynamics and well-being of patient by reducing ventricular asynchrony. Recently, we underwent biventricular DDD pacemaker implantation in a patient with CHF and Left bundle branch block and was significantly improved exercise tolerance and quality of life in that patient.

朝鮮後期 自治와 抵抗組織으로서의 鄕會

安秉旭 聖心女子大學校 1986 論文集 Vol.18 No.-

KSDeNTM 공정에서 C/P 비, SRT, 온도 및 질산염 농도가 인 제거에 미치는 영향

김병군,서인석,홍성택,김도군,천상욱 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

In this study, the effects of C/P ratio, SRT, temperature and nitrate concentration on the phosphorus removal efficiency of KSDeN™ process (KOWACO-Ssangyong DeNutrient process) was investigated with a pilot plant, which is fed with the grit chamber effluent of 'J' MWWTP (Municipal Wastewater Treatment Process). During the operating period, T-P removal efficiency was more than 80% at C/P ratio (TCOD_Cr/T-P ratio) of 35 or above, and it was higher at relatively low temperature and high C/P ratio. At SRT (Sludge Retention Time)'s of 3-28 days, phosphorus removal efficiency increased up to 90% until the SRT reached 20 days. The phosphorus removal efficiency decreased rapidly with more than 20 days of SRT, which showed that the optimal SRT is 20 days for the T-P removal of KSDeN™ process. Effluent T-P concentration increased with increasing temperature. It is considered that the competition on organic compounds between PAOs (Phosphorus Accumulating Organisms) and denitrifiers resulted in lowering T-P removal by activating nitrifiers at 15℃ or above. The release of phosphorus was influenced by nitrate concentration in anaerobic/anoxic tank. When the nitrate concentration was higher than 2 ㎎/L, the release of phosphorus was disturbed by denitrifiers. SCOD and PO^3-_4-P profile with each reactors of KSDeN™ process showed typical behavior of phosphorus release and luxury uptake by PAOs.

심인성 신체화 증상의 좌우 편재

이병욱,남궁기,민성길 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

Objects : The purpose of this study was to examine chief somatic complaints and their correlation to laterality in the body, and severity of anxiety and depression. Methods : The sixty-one patients were examined. The diagnostic criteria used was DSM-Ⅲ-R. The severity of depression and anxiety was assessed with Hamilton's depression scale and Hamilton's anxiety scale, respectively. The demographic data of the subjects were also analyzed. Results : The chief psychogenic somatic symptoms that were complained by patients occurred significantly more on the left side than on the right side(Left : Right : Both=62.3% : 19.7% : 18.0%). Headache was the most common somatic symptoms and headache and other symptoms were significantly more on the left. The demographic data did not make a difference between the left and right-sided groups. The diagnosis did not make a difference between the left and right-sided groups. The score of anxiety or depression were higher in the left-sided group than the right-sided group, but not statistically significant. conclusions : These results suggest that the laterality of psychogenic somatic symptoms seems to be more related with left hemisphere.

이갈이 환자의 다면적 인성검사의 특성

박병욱,이희철,장문정,심주철 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.3

연구목적 : 다면적 인성검사를 통해 이갈이군의 심리적 특성을 알아보고 이갈이 환자의 성별, 가족력, 발병기간, 이갈이 유형, 동반된 통증 유무에 따른 심리적 특성의 차이를 알아보고자 하였다. 방 법 : 1998년 1월부터 8월까지 개인 치과의원을 방문한 환자들 중 46명의 이갈이군, 41명의 대조군을 대상으로, 이갈이군과 대조군의 심리적 특성, 이갈이 환자의 성별, 가족력 유무, 이갈이 기간, 이갈이 유형, 통증과 같은 동반증상유무에 따른 심리적 특성의 차이를 알아보기 위해 다면적 인성검사를 실시하였다. 결 과 : 이갈이군이 대조군보다 모든 임상척도에서 높은 점수를 나타냈으나 남성특성-여성특성 척도점수를 제외하고는 통계적 유의성이 없었다. 가족력이 있는 이갈이군이 가족력이 없는 이갈이군보다 반사회성 척도가 높았다. 이갈이군에서 남자가 여자보다 교정척도(K) 점수가 높게 나타났으며 여자는 편집증 척도점수가 높게 나타났다. 발병기간에 따른 차이는 없었으며 이갈이 종류의 비교에서는 이악물기형이 다른형보다 내향성 척도가 유의하게 높았다. 저작근 통증, 경통, 두통과 같은 동반된 통증 유무에 따른 차이는 없었다. 결 론 : 다면적 인성검사상 일부 항목에서 높은 점수를 나타낸 것으로 이갈이 환자의 심리적 특성을 규정짓기는 어려우나 이갈이군이 대조군에 비해서 다면적 인성검사상 모든 척도가 상승되어 있고, 이갈이의 성별, 가족력, 이갈이의 종류에 따라 일부 척도의 점수가 상승되어 있는 것은 이들이 서로 다른 심리적 특성을 가질 가능성을 시사한 것이라고 판단되며, 이는 치료에 있어서도 좀 더 개별화된 접근이 필요함을 시사한다. Objectives : The aim of this study was to evaluate the psychological characteristics of the patients with bruxism by Minnesota Multiphase Personality Inventory (MMPI). Methods : MMPI was administered to 87 patients(46 bruxism group and 41 control group) who had visited a local dental clinic from January to August 1998. Results : The bruxism group had a higher score than control group in Masculinity-Femininity (Mf) scale. There were no differences between bruxism group and control group on the distribution of Depression(D), Psychopatic Deviate(Pd), Paranoia(Pa), Psychasthenia(Pt) scales. The bruxism group with the family history showed higher score than the bruxism group without family history in Pd scale. Male bruxism group had a higher score than female bruxism group in Defensiveness(K) scale and female bruxism group had higher score than male bruxism group in Pa scale. The bruxism group of clenching type had a higher score than the bruxism group of mixed type in Social Introversion(Si) scale. There were no differences in MMPI score between those who had and did not have symptoms such as masticatory muscle pain, neck pain, and headache. Conclusion : It is concluded that individualized approach may be effective to the evaluation of psychological disturbances which might be related to sex, family history and, type of bruxism, while we did not find significant differences in personality characteristics between the bruxism and control groups.

兩側 및 單側 電氣衝擊療法後의 腦波變化에 對한 硏究

楊秉煥,정경천,李定均,卞容旭 大韓神經精神醫學會 1979 신경정신의학 Vol.18 No.2

Changes on EEG after bilateral and unilateral ECT was studied in 12 young adult schizophrenic patients who were admitted st Seoul Municipal Mental Hospital. Their EEC data were obtained during the interictal period of serial ECT sessions and subjected to global quantitative analysis by visual assessment. Some significant findings are summarizcol as follows: Repeated ECT resulted in increased EEG slow wave activity more see in the frontal and temporal leads which became gradually generalized in forms of occasional burst and run. No spike and focalized activities were seen. The degree of slowing and its amplitude was directly related to the number of ECT sessions. As the successive four to six treatments were administered, the slowing became more persistent and widespreaded with high voltage paroxysmal activities, while the alpha rhythm became disturbed and disappeared. After seven to eight serial treatment, the percent time delta remained constant in plateau or falled off. Fourteen days after the last 10th treatment, 34 percent time of slow wave activities was recorded in frontal lead of bilateral ECT group and 25 percent of unilateral ECT group. Minor lateralized asymmetries of frequancy and amplitude which were predominently right sided, appeared more in the right unilateral ECT group (4 in 6 cases) than the bilateral group (1 in 6 cases). The amount of post-ECT slow wave activity did not revealed major difference between these kinds of ECTs and was closely related to the number of ECT sessions and to the pretreatment EEG with individual variations. No relationship was found between the therapeutic response, degree of amnesia or confusion, and EEG findings after electroconvulsive therapy.

核然料에 關한 硏究 : α-UO_3의 構造的 特性 Structural Characteristics of α-UO_3

李秀一,曺秉旭,洪光俊 조선대학교 기초과학연구소 1984 自然科學硏究 Vol.7 No.1

α-UO_3 have been prepared from uranyl acetate solution by the thermal decomposition method. The materials structure were examined by surface morpholgy, X-ray diffraction and optical density spectrum. The results showed that α-UO_3 exists two different crystalline forms depending on the temperature of precipitation ; hexagonl α-UO_3 at 350℃ and orthorhombic α-UO_3 at 600℃.