국소침 윤마취시 Epinephrine 효과에 대한 관찰

金鳳謙,金容培,方裕鉉,朴種燮,柳在德 大韓成形外科學會 1983 Archives of Plastic Surgery Vol.10 No.1

The local anesthetics play a central and frundamental role, for they comprise, probably, the single most widely used group of durgs in the field of plastic surgery. Also many plastic surgical procedures require the use of a vasoconstrictor to reduce operative bleeding under both general and local anesthesia. Among local anesthetics, lidocaine, introduced by Lofgren in 1948, is one of most widely used local anesthetics and most frequently used for infiltration anesthesia with 0.5% to 1 0%solution. Also eqinephrine is one of the most potent and most useful vasoconstrictors for admixture with thesolution of local anesthetics for infiltration of tissue. In the clinical practice, it has been said that the concentration of lidocaine and epinephrine should be kept at the minimal level of effectiveness because of the epinephrine performs a dual service when is combined with lidocaine. In order to clarify the minimum concentration of the lidocaine and epinephrine respectively necessary for adequate duration of anesthesia, with less irritation of local tissue and less bleeding, the clinical observation and animal experiment were undertaken, and the following results were summarized. The most effective skin blanching by epinephrine was obtained with epinephrine concentration of 1 : 50,000 although some effect was still presented with epinephrine concentration of 1 : 800,000. The onset of maximum skin blanching following the local infiltration of lidocaine with epinephrine(1 : 50,000 to 1 : 400,000) was within 5 minutes and was lasting 20 to 40 minutes. When the skin incision was made 5 minutes to 15 minutes following local infiltration of epinephrine, the amount of bleeding was markedly decreased and no significant difference in the time of hemostasis was noticed(p〉0.1). Also no significant difference in the time of hemostasis was noticed in the different concentration (1 : 100,000 and 1 : 200,000) of epinephrine(p〉0.1). The optimum concentration of epinephrine is between 1 : 200,00 to 1 : 400,000 solution and the optimum concentration of lidocaine is 0.5%.

Consistency of The Kernel Estimators for Testing The Parallelism of Regression Lines

신봉섭 대신대학교 자연과학연구소 1994 自然科學硏究 Vol.1 No.-

송문섭외 3인 (1993)은 순서대립가설에 대하여 k개의 회귀직선이 평행한가를 검정하는 검정법을 제안하였다. 그들이 제안한 검정법은 Adichie (1976)의 점수통계량(scores test) 을 수정 한 것으로, 기울기의 Hodges-Lehmann 형태 추정량의 선형결합과 L_1-노름 추정량의 선형결합이다. 또한 검정통계량의 극한분산이 모집단에 의존하기 때문에 혼합잔차들을 이용한 커넬(kernel)추정을 사용하였다. 본 논문에서는 송문섭외 3인이 이용한 커넬추정량들이 각 직선에서의 표본수가 동일하다는 조건하에서 일치추정량임을 증명하였다. For the problem of testing the parallelism of several regression lines against ordered alternatives, Song et al. (1993) proposed the modified tests of Adichie (1976)'s scores test. Their tests are linear combinations of the robust estimators of slopes such as the Hodges-Lehmann type estimators and the L_1-norm estimators. Since the asymptotic variances of their test statistics include the quantities which depend on the underlying error distribution, they used the kernel esimates of these quantities. In this thesis, the corresponding kernel estimators are proved to be consistent.

확률분포의 난수생성기 제작과 활용에 관한 연구

신봉섭,권희용 안양대학교 자연과학연구소 1996 自然科學硏究 Vol.3 No.-

본 논문에서는 통계적 모의실험에서 자주 사용되는 여러 확률분포에 따르는 난수들의 생성기를 구현하고, 제작된 난수생성기가 실제 모의실험에서 유용하게 활용될 수 있음을 보였다. 구현된 난수생성기는 FORTRAN의 함수부프로그램이나 SUBROUTINE으로 제작되어 라이브러리로 구성한 것이다. 따라서 사용자가 간단한 link-과정을 통해 쉽게 활용할 수 있다. 또한 구현된 라이브러리의 각 SUBROUTINE들은 여러 가지 통계적인 검증을 거쳐 안정성을 확인하였고, 실제 모의실험을 통해서도 안정성에 문제가 없음을 볼 수 있다. In this thesis, a library of random number generators for various statistical distributions which often used in stochastic simulation is implemented and applied to the real situation of statistical simulation. The implemented library contains FORTRAN routines which are in the form of FUNCTION or SUBROUTINE, and thus user can simply use this library by linking it. Each routine of the implimented library was tested by the various procedures and proved to be very stable. This stability was also obtained through the real simulation.

통계교육용 통계소프트웨어의 구현에 대한 소고

신봉섭,최은홍 안양대학교 산업기술연구소 2004 自然科學硏究 Vol.11 No.1

본 연구는 통계교육에 활용할 수 있도록 고안된 통계소프트웨어 Basic_Stat의 구현과정과 실행과정을 다루었다. Basic_Stat에는 통계학에서 기본적으로 사용하는 확률분포들의 확률 및 분위수 계산과 기술통계량, 단일 표본과 두 개의 표본에서 모수(모평균, 모분산, 모비율 등)에 대한 추정과 검정, 분산분석법, 상관분석 및 회귀분석 등 기초통계학에서 다루는 내용들을 포함하고 있다. This paper deals with the implementation of the BASIC_STAT, which is a statistical software for statistics education. The BASIC_STAT contains various procedures useful for introductory statistics. Computing probabilities and quantiles of various statistical distributions, computing descriptive statistics, statistical inference about the population parameters of one or two samples, analysis of variation, correlation analysis, and regression analysis are available.

폐결핵치료 중인 환자에서 Rifampicin에 의해 유발된 위막성 대장염 2예

김봉진,권균홍,임창섭,김자영,홍정범,옥미선,배용목,김지연 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Pseudomembranous colitis (PMC) is a disease caused by Clostridium difficile proliferation. The causative drugs are clindamycin, third-generation cephalosporins, flouroquinolone and so on. Rifampicin has been reported as a cause of PMC in the 1980s, and the frequency of PMC is increasing because rifampicin is a first line drug for anti-tuberculosis therapy. Two patients were recently admitted to our hospital due to watery diarrhea for 1 month and they were diagnosed with PMC by sigmoidoscopy. Their onset age were 74, 72 years old and latent period of symptoms were 60, 129 days, respectively. In one case, the patient displayed coexisting hypertension and diabetes. The clinical symptoms improved after discontinuing the rifampicin and then administering oral metronidazole. We report here on two cases presumed to be rifampicin-induced PMC.

불균일 Winkler 탄성 기초위에 놓인 보의 자유진동과 안정성

최봉문,윤영식,윤충섭,류봉조 建陽大學校 1999 建陽論叢 Vol.- No.7

The paper deals with free vibration and stability analysis of a uniform Euler-Bernoulli beam resting on non-uniform Winkler elastic foundation. governing equations for the system are derived by using energy expressions. Solutions are approximately and numerically calculated by means of the finite element formulation. The solutions in the present paper are compared with other available ones without axial force. Finally, stability for cantilever and simply supported beams under a pure axial force is investigated.

구속운동을 받는 외팔보의 혼돈진동

최봉문,류봉조,윤충섭,임경빈 大田産業大學校 2000 한밭대학교 논문집 Vol.17 No.1

When the motion of vibrating structure is restrained by the adjacent objects, its vibration frequencies and mode shapes are changed. In general, the vibration characteristics of the system becomes unpredictable. Although the importance of the study on this type of vibration model increases in many engineering areas, most studies conducted to date were focused to the theoretical study on dynamic responses of the structure with stops, including a few experimental works. Specially, the study on the nonlinear phenomena due to the impact between a structure and stops have been mainly performed theoretically. It is, therefore, desired to find a way to have a better understanding on the vibration characteristics caused by the impact of a structure to stops. In the paper, both numerical analyses and experiments are conducted for a fixed-free beam that is restrained by the stops at the free end. The chaotic vibration characteristics of the nonlinear motion and the dynamic response of the system are investigated and presented for various magnetic forces between stops.

Vinyl腐蝕法에 依한 在來山羊 脾柱靜脈의 區域的 走行에 關한 硏究

金鍾涉,金武剛,金容根,元鳳來 慶尙大學校 1972 論文集 Vol.11 No.-

The studies were conducted to observe the segmental running of splenic trabecular veins, employing the vinylite corrosion technique in sixty adult Korean goats, and the following results were obteined: 1. The splenic trabecular veins of the goat were collected into 5 chief Rami of the splenic veins(called Rr. superior, media et inferior, Vv. polares superior et inferior), and the splenic parenchyma was divided into 3-8 intralienal venous segments by the course of trabecular veins. 2. Each intralienal venous segment was divided into 2-4 minute segments, therefore 7-22 minute segments were observed in the spleen. 3. The anastomoses were found between segments or minute segments. 4. The splenic arterial and venous system of the Korean goat took a individual course in the splenic parenchyma respectively.

일단계 GM-추정량을 이용한 두 회귀직선의 평행성 검정

심봉섭 안양대학교 자연과학연구소 1998 自然科學硏究 Vol.5 No.1

본 논문에서는 최대붕괴점과 유계영양함수를 갖는 일단계 GM-추정량을 이용하여 두 회귀직선의 평행성을 검정하는 로버스트 검정법을 제안하였다. 제안된 검정법은 Song et al.(1994,b)에 의하여 제안된 최소절단제곱 추정량을 초기치로 하는 일단계 GM-추정량에 근거하고 있으며, 모의실험과 예를 통하여 기존의 방법들보다 유의수준의 안정성과 검정력의 측면에서 매우 우수한 결과를 얻었다. For the problem of testing the parallelism of two regression lines, a robust procedure is proposed and examined. The proposed test statistic is based on the one step GM-estimators of slope parameters proposed by Song et al.(1994,b). These GM-estimators used the Leasst Trimmed Squares estimates as an initial values so as to obtain high breakdown point. Through a smll-sample Monte Carlo simulation the empirical levels and powers of proposed test are compared with other tests under various error distributions.

불확실성하에서의 손해보험회사 포트폴리오관리

정요섭,홍봉영 漢陽大學校 産業經營硏究所 1998 産業經營硏究 Vol.10 No.-